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| 1 | A single administration of fish oil inhibits the acute inflammatory response in rats显示文摘Objective: To investigate the antiinflammatory effects of a single administration of fish oil(FO) on the acute inflammatory response. Methods: The paw edema and pleurisy models were used to evaluate the effects of FO dissolved in olive oil(FOP) orally administered in a single dose in rats. Nitric oxide(NO) concentrations in the pleural exudate were performed according to the Griess method and the cytokine concentrations were determined by Luminex bead-based multiplex assay. Results: FOP treatment(30 and 300 mg/kg) significantly reduced paw edema. FOP treatment at 18.75, 37.5, 75.0, 150.0, and 300 mg/kg decreased both the volume of pleural exudate and cellular migration into the pleural cavity and each of these doses presented the same effectiveness. Treatment with FOP(300 mg/kg) reduced NO, TNF-α, IL-1β, and IL-6 concentrations in the pleural exudate. Conclusions: The present data provide evidence that FO has inhibitory effects on the acute inflammatory response when administered in a single dose in rats. This effect might be attributable to a direct inhibitory effect of FO on the production or release of inflammatory mediators that are involved in the pathological processes evaluated herein. | Laura Licia Milani de Arruda Franciele Queiroz Ames Damila Rodrigues de Morais Renata Grespan Ana Paula Maziero Gil Maria Angelica Raffaini Covas Pereira Silva Jesui Vergilio Visentainer Roberto Kenji Nakamura Cuman Ciomar Aparecida Bersani-Amado | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，8： | 2 |
| 2 | Contribution of hip abductor strength to physical function in patients with total knee arthroplasty显示文摘 | Piva SR Teixeira PE Almeida GJ Gil AB DiGioia AM 3rd Levison TJ Fitzgerald GK | 2011 | Physical therapy2011，91，2： | 1 |
| 3 | Osteolysis associated with cemented total knee arthroplasty显示文摘 | Griffin FM Scoderi GR Gil is AM | | 0，，05： | 1 |
| 4 | Epidemiology of advanced Therapies fur the treatment of Diabetic foot ulcers in outpatient care settings显示文摘 | AM Gil|igan CR Waycaster | 2015 | Value in Health2015，18，3： | 1 |
| 5 | Fasciola hepatica:humoral and cytokine responses to a member of the saposin-like protein family following delivery as a DNA vaccine in mice显示文摘 | Espino AM Osuna A Gil R | 2005 | Exp Parasitol2005，110，4： | 1 |
| 6 | Advances in the treatment of prolactinomas显示文摘 | Gil|am MP Molitch ME Lombardi G | 2006 | Endocr Rev2006，27，5： | 1 |
| 7 | Assessment of sperm factors possibly involved in early recurrent pregnancy loss 显示文摘 | Gil - Villa AM Cardona - Maya W Agarwal A | 2010 | Fertil Steril2010，94，4： | 1 |
| 8 | Nutrient uptake rates by the alien alga Undaria pinnatifida (Phaeophyta) (Nuevo Gulf, Patagonia, Argentina) when exposed to diluted sewage effluent显示文摘 | Américo I. Torres Mónica N. Gil José L. Esteves | 2004 | Hydrobiologia (-)2004，，1： | 1 |
| 9 | NMR relaxometry and MRI for food quality control:Application to dairy products and processes显示文摘 | Belton PS Gil AM Webb GA | | 0，，： | 1 |
| 10 | Quality control of reactive oxygen species measurement by luminol - dependent chemiluminescence assay 显示文摘 | Kobayashi H Gil - Guzman E Mahran AM | 2001 | J Androl2001，22，4： | 1 |
| 11 | Quality control of reactive oxygen species measurement by luminol - dependent chemiluminescence assay显示文摘 | Kobayashi H Gil - Guzman E Mahran AM | 2001 | J Androl2001，22，4： | 1 |
| 12 | Multidrug resistance gene (MDRI) expression in the colonic mucosa of patients with refractory ulcerative colitis显示文摘 | Sambuelli AM Negreira SM Gil AH | | 0，，01： | 1 |
| 13 | Agenesis of the infe-rior vena cava associated with lower extremities and pelvic ve- nous thrombosis显示文摘 | Gil RJ Perez AM Arias JB | 2006 | J Vasc Surg2006，44，5： | 1 |
| 14 | Fasciola hepatica: humoral and cytokine responses to a member of the saposin-like protein family following delivery as a DNA vaccine in mice 显示文摘 | Espino AM Osuna A Gil R | 2005 | Exp Parasitol2005，110，4： | 1 |
| 15 | Managing dentin hypersensitivity显示文摘 | Orchardson R Gil am DG | | 0，，07： | 1 |
| 16 | Surgical planning and microvascular reconstruction of the mandible with a fibular flap using computer-aided design, rapid prototype modelling, and precontoured titanium reconstruction plates: a prospective study显示文摘 | Sieira Gil R Roig AM Obispo CA | 2015 | Br J Oral Maxillofac Surg2015，53，1： | 1 |
| 17 | The effects of a novel bioglass dentifrice on dentine sensitivity:a scanning electron microscopy investigation显示文摘 | Gil am DG Tang JY Mordan NJ | | 0，，： | 1 |
| 18 | Role of heparanase-driven inflammatory cascade in pathogenesis of diabetic nephropathy显示文摘 | Goldberg R Rubinstein AM Gil N | 2014 | Diabetes2014，63，12： | 1 |
| 19 | Metabolic signatures of cancer unveiled by NMR spectroscopy of human biofluids显示文摘 | Duarte IF Gil AM | 2012 | Prog Nucl Magn Reson Spectrosc2012，62，： | 1 |
| 20 | Study of compositional changes of Mango during ripening by use of nuclear magnetic resonace spectroscopy显示文摘 | Gil AM Durate IF Delgadillo I | 2000 | J Agric Food Chem2000，48，： | 1 |
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