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| 1 | Clarithromycin resistance in Helicobacter pylori and its clinical relevance显示文摘 | Xia HX Fan XG Talley NJ | 1999 | World Journal of Gastroenterology1999，5，3： | 26 |
| 2 | Localization of HCV RNA and capsid protein in human hepatocellular carcinoma显示文摘INTRODUCTIONThe relation of HCV to hepatocytic carcinoma(HCC) has been emphasized recently in low HBVinfection countries and regions.The distributionpatterns of HCV in liver tissues are not wellunderstood although studies on HCV infection inblood and hepatocytes have been conducted byPCR.In this study,42 liver cancers | Dai YM Shou ZP Ni CR Wang NJ Zhang SP | 2000 | World Journal of Gastroenterology2000，6，1： | 15 |
| 3 | 功能性消化不良、胃排空延迟和生活质量下降显示文摘功能性消化不良(FD)是一种临床上最常见的综合征,表现为慢性反复性中上腹疼痛或不适,传统的诊断检测方法不能检测出病因。许多FD患者诉说症状与饮食有关,但病理生理情况不明。25%~50%的FD患者发生胃排空延迟症状,这与胃窦部动力降低有关。其他FD的异常表现包括胃底容受性限制、胃扩张过度敏感和幽门螺杆菌(H.pylori)感染。 | Talley NJ Locke Ⅲ GR Lahr B Zinsmeister AR Tougas G Ligozio G Rojavin MA Tack J.Mayo Clinic Rochester MN 陆红 | 2006 | 胃肠病学2006，11，2： | 12 |
| 4 | 孕前血压及其到妊娠早期的变化:先兆子痫和妊娠期高血压的早期危险因素显示文摘先兆子痫和妊娠期高血压是常见的妊娠并发症,与母婴发病率显著相关。尽管对怀孕期间的危险因素进行了广泛的研究,但大多数患妊娠期高血压疾病的妇女并不被认为是高风险的,预防措施仍不清楚。研究者评估了妊娠前的血压及其到妊娠早期的变化,将其作为妊娠高血压疾病发展新的危险标志。 | 刘青(译) 刘莉(摘/审校) Nobles CJ Mendola P Mumford SL Silver RM Kim K Andriessen VC Connell M Sjaarda L Perkins NJ Schisterman EF | 2020 | 中华高血压杂志2020，28，12： | 12 |
| 5 | Static Theory for Planar Ferromagnets and Antiferromagnets | Feng Bo HANG Fang Hua LIN Courant Institute, 251 Mercer Street. New York. NY 10012, USA Dept. of Math, Princeton University, Fine Hall. Washington Road, Princeton, NJ 08544 USA. | 2001 | Acta Mathematica Sinica,English Series2001，17，4： | 8 |
| 6 | 埃索美拉唑能有效控制内镜阴性胃食管反流症状——6个月“按需治疗”对照试验显示文摘 | Talley NJ Lauritsen K Tunturi-Hihnala H Lind T Moum B Bang C Schulz T Omland TM Delle M Junghard O 钟捷 | 2003 | 中华消化杂志2003，23，1： | 6 |
| 7 | 混凝土对模板的侧压力显示文摘 | Gard.,NJ 许贤敏 | 1991 | 国外建筑科学1991，9，3： | 6 |
| 8 | road to stemness in hepatocellular carcinoma显示文摘Carcinogenic process has been proposed to relay on the capacity to induce local tissue damage and proliferative repair. Liver has a great regeneration capacity and currently, most studies point towards the dominant role of hepatocytes in regeneration at all levels of liver damage. The most frequent liver cancer is hepatocellular carcinoma(HCC). Historical findings originally led to the idea that the cell of origin of HCC might be a progenitor cell. However, current linage tracing studies put the progenitor hypothesis of HCC origin into question. In agreement with their dominant role in liver regeneration, mature hepatocytes are emerging as the cell of origin of HCC, although, the specific hepatocyte subpopulation of origin is yet to be determined. The relationship between the cancer cell of origin(CCO) and cancer-propagating cells, known as hepatic cancer stem cell(HCSC) is unknown. It has been challenging to identify the definitive phenotypic marker of HCSC, probably due to the existence of different cancer stem cells(CSC) subpopulations with different functions within HCC. There is a dynamic interconversion among different CSCs, and between CSC and non-CSCs. Because of that, CSC-state is currently defined as a description of a highly adaptable and dynamic intrinsic property of tumor cells, instead of a static subpopulation of a tumor. Altered conditions could trigger the gain of stemness, some of them include: EMT-MET, epigenetics, microenvironment and selective stimulus such as chemotherapy. This CSC heterogeneity and dynamism makes them out reach from therapeutic protocols directed to a single target. A further avenue of research in this line will be to uncover mechanisms that trigger this interconversion of cell populations within tumors and target it. | Teresita NJ Flores-Téllez Saúl Villa-Trevino Carolina Pina-Vázquez | 2017 | World Journal of Gastroenterology2017，23，37： | 4 |
| 9 | Polylogarithms and multiple zeta values from free Rota-Baxter algebras显示文摘We show that the shuffle algebras for polylogarithms and regularized MZVs in the sense of Ihara,Kaneko and Zagier are both free commutative nonunitary Rota-Baxter algebras with one generator.We apply these results to show that the full sets of shuffle relations of polylogarithms and regularized MZVs are derived by a single series.We also take this approach to study the extended double shuffle relations of MZVs by comparing these shuffle relations with the quasi-shuffle relations of the regularized MZVs in our previous approach of MZVs by renormalization. | GUO Li1,2 & ZHANG Bin3,1Center of Mathematical Sciences,Zhejiang University,Hangzhou 310027,China 2Department of Mathematics and Computer Science,Rutgers University,Newark,NJ 07102,USA 3Yangtze Center of Mathematics,Sichuan University,Chengdu 610064,China | 2010 | Science China Mathematics2010，53，9： | 4 |
| 10 | Post-cholecystectomy symptoms were caused by persistence of a functional gastrointestinal disorder显示文摘AIM:To classify gallstone disease as a basis for assessment of post-cholecystectomy symptoms.METHODS:One hundred and fifty three patients with a clinical and ultrasonographic diagnosis of gallstones filled out a structured questionnaire on abdominal pain symptoms and functional gastrointestinal disorder (FGID) before and at six months after cholecystectomy.Symptom frequency groups (SFG) were categorized according to frequency of pain attacks.According to certain pain characteristics in gallstone patients,a gallstone symptom score was accorded on a scale from one to ten.A visual analogue scale was used to quantify pain.Operative specimens were examined for size and magnitude of stone contents as well as presence of bacteria.Follow-up took place after six months with either a consultation or via a mailed questionnaire.Results were compared with those obtained pre-operatively to describe and analyze symptomatic outcome.RESULTS:SFG groups were categorized as severe (24.2%),moderate (38.6%) and mild (22.2%) attack frequency,and a chronic pain condition (15%).Pain was cured or improved in about 90% of patients and two-thirds of patients obtained complete symptom relief.Patients with the most frequent pain episodes were less likely to obtain symptom relief.FGID was present in 88% of patients pre-operatively and in 57% postoperatively (P=0.244).Those that became asymptomatic or improved with regard to pain also had most relief from FGID (P=0.001).No pre-operative FGID meant almost complete cure.CONCLUSION:Only one third of patients with FGID experienced postoperative relief,indicating that FGID was a dominant cause of post-cholecystectomy symptoms. | Malte Schmidt Karl Sφndenaa John A Dumot Steven Rosenblatt Trygve Hausken Maria Ramnefjell Gro Njφlstad Geir Egil Eide | 2012 | World Journal of Gastroenterology2012，18，12： | 4 |
| 11 | 内镜医师眼中胃肠病学家在未来消化肿瘤学中的作用显示文摘消化肿瘤学的发展需要创建一个多学科的团队。专攻消化肿瘤学的胃肠病学专家(肿瘤-胃肠病学家)也应该包含在这样高质量的团队中。为实现这一目标,肿瘤-胃肠病学家需接受与消化道肿瘤内镜诊断和治疗所有相关方面的充分培训。本文涵盖所有需要用来保证最佳诊治的专业技术。 | Guido NJ TYTGAT 陈海英 戈之铮 钱本余 | 2013 | 胃肠病学2013，18，8： | 3 |
| 12 | Apoptosis in gastric epithelium induced by helicobacter pylori infection: implications in gastric carcinogenesis显示文摘 | XIAHH TALLEY NJ | 2001 | Am J Gastroenterol2001，96，： | 3 |
| 13 | WONCA研究论文摘要汇编——患者安全素养干预对全科医学事故报道的影响:一项整群随机化试验显示文摘背景有益安全素养对有效提高患者安全性来说必不可少。目的评估两种患者安全素养干预对全科医学事故报道的影响。设计和地点使用混合方法进行一项整群随机化试验,在荷兰30所全科医学诊所进行患者安全素养问卷调查(干预1组)、以实践为基础的研讨会作为补充的问卷调查(干预2组)和无干预(控制组),研究这3种情况的效果。方法首要结局指标是全科医学事故报道数量,于研究开始和研究1年后进行评估。使用负二项式模型对数据进行分析。次要结局指标是质量、安全指标和安全素养。对安全素养问卷进行混合效果线性回归分析。结果干预1组与干预2组的全科医学事故报道数量均有所增长,分别增加了82个和224个。依据基线全科医学事故数量、诊所规模和认证状态进行调整,研究表明干预2组诊所全科医学事故报道数量是控制组诊所的42倍〔95%CI(9.81,177.50)〕,干预1组诊所全科医学事故报道数量是控制组诊所的5倍〔95%CI(1.17,25.49)〕。在随访调查中,3组患者安全素养员工感知方面比较,差异无统计学意义(P<0.05)。结论员工接受患者安全素养教育和进行相关讨论能够提高全科医学事故报道数量,增加相关团队智慧投入,有利于提高患者安全性。 | Verbakel NJ Langelaan M Verheij TJ 本刊编辑部 | 2015 | 中国全科医学2015，18，24： | 3 |
| 14 | 头颈部鳞癌术前放疗还是术后放疗——208例临床分析显示文摘近十年来,手术与放射的综合治疗已成为中晚期头颈部鳞癌的重要治疗手段之一。但放疗在术前、术后应用何者为优的问题仍在不断探索之中。从1964年10月至1985年4月,208例头颈部鳞癌患者在佛罗里达大学医学院采用手术与放射的综合治疗,其中术前放疗74例,术后放疗134例,现将二组疗效对比分析如下,以探讨治疗模式对治疗结果的影响。 | 王中和 RR米列奥 NJ卡西西 | 1991 | 中华放射肿瘤学杂志1991，0，3： | 3 |
| 15 | BATE curve in assessment of clinical utility of predictive biomarkers显示文摘In this paper,for time-to-event data,we propose a new statistical framework for casual inference in evaluating clinical utility of predictive biomarkers and in selecting an optimal treatment for a particular patient.This new casual framework is based on a new concept,called Biomarker Adjusted Treatment Effect (BATE) curve.The BATE curve can be used for assessing clinical utility of a predictive biomarker,for designing a subsequent confirmation trial,and for guiding clinical practice.We then propose semi-parametric methods for estimating the BATE curves of biomarkers and establish asymptotic results of the proposed estimators for the BATE curves.We also conduct extensive simulation studies to evaluate finite-sample properties of the proposed estimation methods.Finally,we illustrate the application of the proposed method in a real-world data set. | ZHOU XiaoHua 1,2,3,& MA YunBei 4,5 1 Northwest HSR&D Center of Excellence,VA Puget Sound Health Care System,Seattle,WA 98198,USA 2 Department of Biostatistics,University of Washington,Seattle,WA 98198,USA 3 Beijing International Center for Mathematical Research,Peking University,Beijing 100871,China 4 Department of Operations Research and Financial Engineering,Princeton University,Princeton,NJ 08540,USA 5 School of Statisitcs,Southwest University of Finance and Economics,Chengdu 611130,China | 2012 | Science China Mathematics2012，55，8： | 2 |
| 16 | Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota显示文摘 | GR Locke NJ Talley SL Fett AR Zinsmeister LJ Melton | 1997 | Gastroenterology1997，，5： | 2 |
| 17 | Iodide transport in a continuous line of cultured cells from rat thyroid显示文摘 | Weiss SJ Philp NJ Grollman EF | 1984 | Endocrinology1984，114，： | 2 |
| 18 | Activated T lymphocytes support osteoclast formation in vitro显示文摘 | Horwood NJ Kartsogiannis V Quinn JM | 1999 | Biochem Biophys Res Commun1999，265，1： | 2 |
| 19 | 1997年亚太地区关于幽门螺杆菌感染处理的共识会议报告显示文摘1997年8月30~31日在新加坡召开了1997关于幽门螺杆菌(Hp)感染处理的亚太地区共识会议。国际专家们作了有关Hp感染各方面最新进展的讲座。来自亚太地区的知名专家对各个地区的前景作了评估、总结。 正式报告后,与会代表们分组出席了诊断、治疗、消化不良和胃癌四个同时召开的工作组会议。 | SK LAM NJ TALLEY 沈兰兰 | 1998 | 胃肠病学1998，3，2： | 2 |
| 20 | 高密度脂蛋白可追踪脑卒中恢复情况显示文摘前瞻性队列研究质疑高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)在脑卒中风险预测中的价值。该文旨在探讨长期功能恢复与高密度脂蛋白(high density lipoprotein,HDL)蛋白质组和功能的关系。方法与结果:测定急性缺血性脑卒中后2个时间点(24小时,35例;96小时,20例)和35例对照组HDL蛋白组成和功能(胆固醇流出能力)的变化。 | Plubell DL Fenton AM Rosario S Bergstrom P Wilmarth PA Clark WM Zakai NA Quinn JF Minnier J Alkayed NJ Fazio S Pamir N 刘青(译) 刘莉(摘/审校) | 2020 | 中华高血压杂志2020，28，11： | 2 |
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