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148篇 您的检索式:作者名="Gavin H"
    题名 作者 年代 出处 被引量
1Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-1igase signaling effector DWARF3显示文摘Li-Hua Zhao X Edward Zhou Wei Yi Zhongshan Wu Yue Liu Yanyong Kang Li Hou Parker W de Waal Suling Li Yi Jiang Adrian Scaffidi Gavin R Flematti Steven M Smith Vinh Q Lam Patrick R Griffin YonghongWang Jiayang Li Karsten Melcher H Eric Xu 2015Cell Research2015,25,11:7
2Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies显示文摘在地岬基因的 Oncogenic 变化在人的癌症是很普通的,导致有描绘得好的选择优点,而且不太听说得好的危险的房间。我们执行了一幅大规模 loss-of-function 屏幕识别被转变 KRAS 的结肠癌房间,然而并非由缺乏这 oncogene 的衍生物要求的基因。最高得分的基因然后在 KRAS 变异、野类型的癌症房间的一块更大的面板被测试。表示 oncogenic KRAS 的癌症房间被发现高度依赖于抄写因素 GATA2 和 DNA 复制开始管理者 CDC6。与已知的目标用许多药扩大这分析,我们发现有变异的 KRAS 的癌症房间与 topoisomerase 抑制显示出选择嗜好到 proteasome 功能,以及合成致命性。联合指向引起的这些功能改善了相对野类型的房间 KRAS 变异的房间杀死。这些观察建议新奇目标和在地岬变异的癌症为最佳的效果联合存在治疗的新方法,它传统地被看作对治疗高度倔强。Michael Steckel Miriam Molina-Arcas Britta Weigelt Michaela Marani Patricia H Warne Hanna Kuznetsov Gavin Kelly Becky Saunders Michael Howell Julian Downward David C Hancock 2012Cell Research2012,22,8:5
3An antigen produced by splicing of noncontiguous peptides in the reverse order 显示文摘Warren E H Vigneron N J Gavin M A 2006Science2006,313,5792:1
4Time,Teams,and Task Performance:Changing Effects of Surface and Deep Level Diversity on Group Functioning显示文摘Harrison D A K H Price J H Gavin A T Florey 2002Academy of Management Journal2002,45,:1
5Application of the coupled MIKE SHE/MIKE 11 modelling system to lowland wet grassland in southeast England 显示文摘Thompson J R Sorenson H R Gavin H 2004Journal of Hydrology2004,293,:1
6Function analysis of microbial communities in aerobic - anaerobic SBR fed with different phosphorus/carbon (P/C) ratios 显示文摘Kong Y H Michael Beer Gavin N R 2002Microbiology2002,148,8:1
7R5 Model for Case-based Reasoning显示文摘Gavin Sun Z H 2003Knowledge--based Systems2003,16,1:1
8Lung function prediction equations derived from health South African gold miners显示文摘Eva H Gavin C Rob D 2000Occup Environ Med2000,57,:1
9High-order limit state functions in the response surface method for structural reliability analysis 显示文摘Gavin H P Yau S C 2008Structural Sofety2008,30,2:1
10Modelling actual,reference and equilibrium evaporation from a temperate wet grassland显示文摘Gavin H Agnew C A 2004Hydrological Processes2004,,18:1
11Application of the coupled MIKE SHE/MIKE 11 modeling system to lowland wet grassland in southeast England显示文摘THOMPSON J R SORENSON H R GAVIN H 2004Journal of Hydrology2004,293,:1
12Electro-rheological damper I : analysis and design 显示文摘Gavin H P Hanson R I) Filisko F E 1996Transactions of the ASME Journal Applied Mechanic1996,63,:1
13A parametric study of linear and non-linear passively damped seismic isolation systems for buildings 显示文摘Alhan C Gavin H 2004Engineering Structures2004,26,4:1
14CD133,a novel marker for human prostatic epithelial stem cells显示文摘Gavin D Craig N Shona H 2004J Cell Science2004,117,16:1
15Microtubule-microfilament Synergy in the Cytoskeleton 显示文摘GAVIN R H 1997Int Rev Cytol1997,173,:1
16Modeling actual, reference and equilibrium evaporation from temperate wet grassland显示文摘Gavin H Agnew C A 2004Hydrological Processes2004,18,2:1
17Activity of glycolyticenzymes in the gut of Hormogaster elisae (OligechaetaHormogastridae) 显示文摘Gavin M H Lattaud C Trigo D 2000Soil Biology & Biochemistry2000,,92:1
18DNA barcoding of Pacific Canada' s fishes 显示文摘Steinke D Zemlak T S Gavin H 2009Mar Biol2009,156,:1
19The chemistry of suspended particulate material in a highly contarninated embayment of port Jackson(Australia) under quiescent,high-wind and heavy-rainfall conditions显示文摘Gavin B Laura O H 0,,03:1
20Application of the coupled MIKE11/MIKE SHE mode- ling system to a lowland wet grassland in southeast England显示文摘THOMPSON J R SRENSON H R GAVIN H 2004Journal of Hydronautics2004,293,14:1
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