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| 1 | Archaea and the human gut:New beginning of an old story显示文摘Methanogenic archaea are known as human gut inhabitants since more than 30 years ago through the detection of methane in the breath and isolation of two methanogenic species belonging to the order Methanobacteriales,Methanobrevibacter smithii and Methanosphaera stadtmanae.During the last decade,diversity of archaea encountered in the human gastrointestinal tract(GIT)has been extended by sequence identification and culturing of new strains.Here we provide an updated census of the archaeal diversity associatedwith the human GIT and their possible role in the gut physiology and health.We particularly focus on the still poorly characterized 7th order of methanogens,the Methanomassiliicoccales,associated to aged population.While also largely distributed in non-GIT environments,our actual knowledge on this novel order of methanogens has been mainly revealed through GIT inhabitants.They enlarge the number of final electron acceptors of the gut metabolites to mono-di-and trimethylamine.Trimethylamine is exclusively a microbiota-derived product of nutrients(lecithin,choline,TMAO,L-carnitine)from normal diet,from which seems originate two diseases,trimethylaminuria(or Fish-Odor Syndrome)and cardiovascular disease through the proatherogenic property of its oxidized liver-derived form.This therefore supports interest on these methanogenic species and its use as archaebiotics,a term coined from the notion of archaea-derived probiotics. | Nadia Gaci Guillaume Borrel William Tottey Paul William O’Toole Jean-Fran?ois Brugère | 2014 | World Journal of Gastroenterology2014，20，43： | 5 |
| 2 | Prognostic impact of cathepsin D and c-erbB-2 oncoprotein in a subgroup of node-negative breast cancer patients with low histological grade tumors显示文摘 | Gaci Z Bouin-Pineau MH Gaci M | 2001 | Int J Oncol2001，18，4： | 1 |
| 3 | Investigation of suspected deficient Fas-mediated apoptosis in a father and son显示文摘 | Hanlon MG Gacis ML Kakakios AM Kilham H | | 0，，： | 1 |
| 4 | GAA instability in Fried- reich' s ataxia shares a conunon, DNA - directed and intraallelic mechanism with other trinucleotide diseases显示文摘 | Gacy AM Goellner GM Spiro C | 1998 | Mol Cell1998，1，4： | 1 |
| 5 | Investigation of suspected deficient Fas-mediated apoptosis in a father and son显示文摘 | Hanlon MG Gacis ML Kakakios AM Kilham H | 2001 | Cytometry2001，43，3： | 1 |
| 6 | Prognosis impact of cathepsin D and cerbB-2 oncoportein in a subgroup of node-negative breast cancer patients with low histological grade tumors 显示文摘 | Gaci Z Bouin-Pineau MH Gaci M | 2001 | Int J Oncol2001，18，4： | 1 |
| 7 | Prognostic impact of cathepsin D and c-erbB-2 oncoprotein in a subgroup of node-negative breast cancer patients with low histological grade tumors显示文摘 | Gaci Z Bouin-Pineau MH Gaci M | 2001 | Int J H Oncol2001，18，4： | 1 |
| 8 | Working through the heart: A transpersonal approach to family support and education 显示文摘 | LE GACY S S | 1998 | Psychiatric Rehabilitation Journal1998，22，2： | 1 |
| 9 | Prognosuie impact of cathepsin D and C-erbB oneoprotrin in a subgroup of modeneganve breast cancer patienes with low histological grade tumors显示文摘 | Gaci Z Bouin Pineou M H Gaci M | 2001 | Inc J Onco2001，18，4： | 1 |
| 10 | Prognostic impact of cathepsin D and c-erbB-2 oncoprotein in a subgroup of nodenegative breast cancer patients with low histological grade tumors 显示文摘 | Gaci Z Bouin-Pineau MH Gaci M | 2001 | Int J Oncol2001，18，4： | 1 |
| 11 | Prognostic impact of cathepsin D and c-erbB-2 oncoprotein in a subgroup of node-negative breast cancer patients with low histological grade tumors显示文摘 | Gaci Z Bouin-Pineau MH Gaci M | 2001 | Int J Oncol2001，18，4： | 1 |
| 12 | Unique Characteristics of the Pyrrolysine System in the 7th Order of Methanogens: Implications for the Evolution of a Genetic Code Expansion Cassette显示文摘 | Guillaume Borrel Nadia Gaci Pierre Peyret Paul W. O’Toole Simonetta Gribaldo Jean-Fran?ois Brugère Kyung Mo Kim | 2014 | Archaea2014，，： | 1 |
| 13 | Three-stage continuous culture system with a self-generated anaerobia to study the regionalized metabolism of the human gut microbiota显示文摘 | David Feria-Gervasio William Tottey Nadia Gaci Monique Alric Jean-Michel Cardot Pierre Peyret Jean-Fran?ois Martin Estelle Pujos Jean-Louis Sébédio Jean-Fran?ois Brugère | 2014 | Journal of Microbiological Methods2014，，： | 1 |
| 14 | Trinucle- otide repeats that expand in human disease form hairpin structures in vitro显示文摘 | GACY A M GOELLNER G JURANIC N | 1995 | Cell1995，81，4： | 1 |
| 15 | Prognostic impact of cathepsin D and C-erbB-2 oncoprotein in a subgroup of node-negative breast cancer patients with low histological grade tumors显示文摘 | Gaci Z Bouin-Pineau MH Gaci M | 2001 | Int J Oncol2001，18，4： | 1 |
| 16 | Tumour cells secrete a vascular permeability factor that promotes accumulation of ascites fluid显示文摘 | Senger DR Gaci SS Dvorak AM | 1983 | Science1983，219，： | 1 |
| 17 | The use of wavelet-based denoising techniques to enhance the first-arrival picking on seismictraces显示文摘 | GACI S | 2014 | IEEE Transactions on Geoscience and Remote Sensing2014，52，8： | 1 |
| 18 | Archaebiotics:proposed therapeuticuse of archaea to prevent trimethylaminuria and cardiovascular disease显示文摘 | Brug^re JF Borrel G Gaci N | 2014 | Gut Microbes2014，5，1： | 1 |
| 19 | Stabilities of intrastrand pyrimidine motif DNA and RNA triple helices显示文摘 | Hoyne P R Gacy A M McMurray C T | | 0，，： | 1 |
| 20 | GAA instability in Friedreich's Ataxia shares a common,DNA-directed and intraallelic mechanism with other trinucleotide diseases显示文摘 | Goellner GM Spiro C | 1998 | Mol Cell1998，1，： | 1 |
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