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| 1 | Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects显示文摘AIM: To establish an association between the serum leptin levels and the development of gallstone disease (GD).METHODS: We carried out a non-matched case-controlled study in a university hospital in Mexico City. Two hundred and eighty-seven subjects were included: 97 cases with gallstones and 190 controls. Body mass index (BMI), fasting plasma leptin, insulin, serum lipid, and lipoprotein levels were measured. Insulin resistance was calculated by homeostasis model assessment (HOMA-IR). Unconditional logistic regression analysis (univariate and multivariate)stratified by BMI was used to calculate the risk of GD.RESULTS: The multivariate conditional regression analysis revealed a model for those patients with BMI <30. The selected variables in the model were HOMA-IR index with OR = 1.31, P= 0.02 and leptin higher than median with OR = 2.11, P= 0.05. In the stratum of BMI ≥30, we did not find a useful model.CONCLUSION: We concluded that insulin resistance and the development of GD appears to be associated with serum leptin levels in subjects with overweight, but not in obese subjects with similar metabolic profiles. | Nahum Méndez-Sánchez Luisa B Bermejo-Martínez Yolanda Vi(n|~)als Norberto C Chavez-Tapia Irina Vander Graff Guadalupe Ponciano-Rodríguez Martha H Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，39： | 11 |
| 2 | Sex-influenced association of nonalcoholic fatty liver disease with coronary heart disease显示文摘 | Mary F. Feitosa Alexander P. Reiner Mary K. Wojczynski Mariaelisa Graff Kari E. North Jeffrey J. Carr Ingrid B. Borecki | 2013 | Atherosclerosis2013，，： | 2 |
| 3 | Translational control of malignancy: the mRNA cap-binding protein, eIF-4E, as a central regulator of tumor formation, growth, invasion and metastasis显示文摘 | Zimmer SG De Benedetti A Graff JR | 2000 | Anticancer Res2000，20，： | 2 |
| 4 | Methylation-specitlc PCR:a novel PCR assay for methylation status of CpG islands显示文摘 | Herman JG Graff JR Myohanen S | 1996 | Proc Natl Acad Sci USA1996，93，18： | 1 |
| 5 | Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands 显示文摘 | Jeremy R Graff JR | 1996 | Proc Natl Acad Sci USA1996，93，18： | 1 |
| 6 | Factors in tonsillectomy mortalily显示文摘 | Alexander D W Graff T D Kelley E | 1965 | Arch Otolaryngol1965，82，4： | 1 |
| 7 | Role of heart-type fatty acid-binding protein in early detection of acute myocardial infarction显示文摘 | Allan HB Graff WL | 2000 | Clinical Chemistry2000，，46： | 1 |
| 8 | Methylation-special PCR:a novel PCR assasy for methylation status of CpG islands显示文摘 | HERMAN J G GRAFF J R MYOHANEN S | 1996 | Proc Natl Acad Sci USA1996，93，： | 1 |
| 9 | Methylation-specific PCR:a novel PCR assay for methylation status of CpG islands显示文摘 | Herman JG Graff JR Myohanen S | 1996 | Proc Natl Acad Sci USA1996，93，18： | 1 |
| 10 | Methylation-specific PCR: a novel PCR assay for methylation status of CpG island显示文摘 | Herman J G Graff R Myohanen S | 1996 | Proc Natl Acad Sci USA1996，93，18： | 1 |
| 11 | Resistant starch has little effect on appetite, food intake and insulin secretion of healthy young men显示文摘 | de ROOS N HEIJNEN M L de GRAFF C | 1995 | European Journal of Clinical Nutrition1995，49，7： | 1 |
| 12 | Expression of group IIa secretory phospholipase A2 increases with prostate tumor grade 显示文摘 | Graff JR Konicek BW Deddens J A | 2001 | Clin Cancer Res2001，7，： | 1 |
| 13 | Use of a remifen- tanil propofol mixture for pediatric flexible fiberoptic broncho scopy sedation显示文摘 | Berkenbosch JW Graff GR Stark JM | 2004 | Paediatr Anaesth2004，14，11： | 1 |
| 14 | Use of a remifentanil-propofol mixture for pediatric flexible fiberoptic bronchoscopy sedation显示文摘 | Berkenbosch JW Graff GR Stark JM | | 0，，11： | 1 |
| 15 | Vitamin D and macular thickness in the elderly:an optical coherence tomography study显示文摘 | Graffe A Beauchet O Fantino B | 2014 | Invest Oph- thalmol Vis Sci2014，55，8： | 1 |
| 16 | Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands显示文摘 | Graff J R Myohanen S | 1996 | Proc Natl Acad Sci USA1996，93，18： | 1 |
| 17 | eIF-4E expression and its role in malig-nancies and metastases显示文摘 | De Benedetti A Graff J R | 2004 | Oncogene2004，23，18： | 1 |
| 18 | Methylation-specific PCR:A novel PCR assay for methylation status of CpG islands显示文摘 | Herman JG Graff JR Baylin SB | 1996 | Proc Natl Acad Sci USA1996，93，： | 1 |
| 19 | Role of heart-type fatty acidbinding protein in early detection of acute myocardial infarction 显示文摘 | Ghani F Wu AH Graff L | 2000 | Clin Chem2000，46，5： | 1 |
| 20 | Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes 显示文摘 | Silva J P Kohler M Graff C | 2000 | Nat Genet2000，26，3： | 1 |
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