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| 1 | Serum leptin levels and insulin resistance are associated with gallstone disease in overweight subjects显示文摘AIM: To establish an association between the serum leptin levels and the development of gallstone disease (GD).METHODS: We carried out a non-matched case-controlled study in a university hospital in Mexico City. Two hundred and eighty-seven subjects were included: 97 cases with gallstones and 190 controls. Body mass index (BMI), fasting plasma leptin, insulin, serum lipid, and lipoprotein levels were measured. Insulin resistance was calculated by homeostasis model assessment (HOMA-IR). Unconditional logistic regression analysis (univariate and multivariate)stratified by BMI was used to calculate the risk of GD.RESULTS: The multivariate conditional regression analysis revealed a model for those patients with BMI <30. The selected variables in the model were HOMA-IR index with OR = 1.31, P= 0.02 and leptin higher than median with OR = 2.11, P= 0.05. In the stratum of BMI ≥30, we did not find a useful model.CONCLUSION: We concluded that insulin resistance and the development of GD appears to be associated with serum leptin levels in subjects with overweight, but not in obese subjects with similar metabolic profiles. | Nahum Méndez-Sánchez Luisa B Bermejo-Martínez Yolanda Vi(n|~)als Norberto C Chavez-Tapia Irina Vander Graff Guadalupe Ponciano-Rodríguez Martha H Ramos Misael Uribe | 2005 | World Journal of Gastroenterology2005，11，39： | 11 |
| 2 | Resistant starch has little effect on appetite, food intake and insulin secretion of healthy young men显示文摘 | de ROOS N HEIJNEN M L de GRAFF C | 1995 | European Journal of Clinical Nutrition1995，49，7： | 1 |
| 3 | Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes 显示文摘 | Silva J P Kohler M Graff C | 2000 | Nat Genet2000，26，3： | 1 |
| 4 | Implications of the spatial variability of landfill emission rates on geospatial analyses 显示文摘 | SPOKAS K GRAFF C MORCET M | 2003 | Waste Management2003，23，7： | 1 |
| 5 | New descriptors of T-wave morphology are independent of heart rate 显示文摘 | Andersen MP Xue JQ Graff C | 2008 | J Electrocardiol2008，41，6： | 1 |
| 6 | Two- frame 3D particle tracking 显示文摘 | PEREIRA F STUER H GRAFF E C | 2006 | Measurement Science & Technology2006，17，7： | 1 |
| 7 | Impaired insulin secretion and beta-cell loss in tissues specific knockout mice with mitochondrial diabetes显示文摘 | Silva J P Kohler M Graff C | 2000 | Nat Genet2000，26，： | 1 |
| 8 | Differential regulation of CDllb on γδ T ceils and monocytes in response to unripe apple polyphenols显示文摘 | Graff J C Jutila M A | 2007 | Journal of Leukocyte Biology2007，82，3： | 1 |
| 9 | Variable modulation of opioid brain uptake by P-glycoprotein in mice显示文摘 | Dagenais C Graff CL Pollack GM | 2004 | Biochem Pharmacol2004，67，2： | 1 |
| 10 | 心电图预激表现与心血管病和死亡风险的关系:哥本哈根心电图研究结果显示文摘大部分心室预激患者临床发病过程中的心电图资料来源于三级医疗中心。为了调查患有心电图预激的初级保健人群的长期预后,来自丹麦哥本哈根Rigshospitalet心脏中心分子心脏病学实验室的研究人员在2001—2011年收集了328638例初级保健患者的电子心电图数据,确定了310例心电图显示预激(年龄8~85岁)的个体。并从丹麦全国注册管理机构获取关于患者药物、合并症和临床结局的资料。随访中位数为7.4(四分位间距4.6~10.3)年。 | 刘莉 叶鹏 Skov MW Rasmussen PV Ghouse J Hansen SM Graff C Olesen MS Pietersen A Torp-Pedersen C HaunsS Kφber L Svendsen JH Holst AG Nielsen JB | 2017 | 中华高血压杂志2017，25，10： | 1 |
| 11 | Nasal drug administration: potential for targeted central nervous system delivery 显示文摘 | Graff C L Pollack G M | 2005 | J Pharm Sci2005，94，6： | 1 |
| 12 | Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes显示文摘 | Silva JP Kohler M Graff C | 2000 | Nat Genet2000，26，3： | 1 |
| 13 | Variable modulation of opioid brain uptake by P-glycoprotein in mice 显示文摘 | Dagenais C Graff CL Pollack GM | 2004 | Biochem Pharmacol2004，67，2： | 1 |
| 14 | The Identification of Spiromesifen,a Recently Introduced Pesticide, Using Approaches to ChemicalUnknown Analysis显示文摘 | WILSON D K GRAFF C L | 2013 | Journal of Forensic Sciences2013，58，1： | 1 |
| 15 | Experiments on membrane filtration of diluent at wastewater treatment plants in the netherlands显示文摘 | Van der Graff J H J M Kramer J F Seytried C F | 1999 | Water Sci Technol1999，39，5： | 1 |
| 16 | A review of the importance of cryptosporidlosis in farm animals 显示文摘 | GRAFF D VANOPDENBOSCH D C ORTEGA E | 1999 | Int J Parasitol1999，29，： | 1 |
| 17 | Reference values of electrocardiogram repolarization variables in a healthy population显示文摘 | HAARMARK C GRAFF C ANDERSEN M P | 2010 | J Electrocardiol2010，43，： | 1 |
| 18 | Variable modulation of opioid brain uptake by P-glycoprotein in mice 显示文摘 | Graff CL Pollack GM Dagenais C | 2004 | Biochem Pharmacol2004，67，2： | 1 |
| 19 | J-shaped association between QTc interval duration and the risk of atrial fibrillation:results from the copenhagen ECG study显示文摘 | Nielsen JB Graff C Pietersen A | 2013 | Joumal of the American College of Cardiology2013，61，25： | 1 |
| 20 | T-wave morphol- ogy reveals greater effect of D, L-sotalol than QTc显示文摘 | GRAFF C ANDERSEN M P XUE J Q | 2008 | J Electro- cardiol2008，41，6： | 1 |
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