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| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | Optimising islet engraftment is critical for successful clinical islet transplantation显示文摘 | O Korsgren T Lundgren M Felldin A Foss B Isaksson J Permert N H Persson E Rafael M Rydén K Salmela A Tibell G Tufveson B Nilsson | 2008 | Diabetologia2008，，2： | 2 |
| 3 | Expression of vascular endothelial growth factor in lymphomas and Castleman's disease 显示文摘 | Foss HD Demel G Klotzbach H | 1997 | J Pathol1997，183，： | 1 |
| 4 | Using professional specialty competencies to guide course development 显示文摘 | Foss G F Janken J K Langford D R | 2004 | Journal of Nursing Educa- tion2004，43，8： | 1 |
| 5 | Tumor necrosis factor receptor-associated factor 1 is overexpressed in Reed-Stemberg cells of Hodgkin's disease and Epstein-Barr virus-transformed lymphoid cells 显示文摘 | Foss H D Demel G | 1999 | Blood1999，93，2： | 1 |
| 6 | Tem- plate-synthesized nanoscopic gold particles: optical spectra and the effects of particle size and shape显示文摘 | Foss Jr C A Hornyak G L Stockert J A | 1994 | J Phys Chem1994，98，： | 1 |
| 7 | On a Voronoi aggregative process related to a bivariate Poisson process 显示文摘 | Foss S G Zuyev S A | 1996 | Advances in Applied Probability1996，28，4： | 1 |
| 8 | Atherosclerotic lesions in lymphoma survivors treated with radiotherapy显示文摘 | Torgeir Wethal B?rd Nedregaard Rune Andersen Alexander Foss? May Brit Lund Anne Günther Stein Kval?y Sophie D. Foss? John Kjekshus | 2013 | Radiotherapy and Oncology2013，，： | 1 |
| 9 | Estrogen and progesterone receptors in salivary gland adenoid cystic carcinoma显示文摘 | Shick P C Riordan G P Foss R D | 1995 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod1995，80，4： | 1 |
| 10 | The effects of photoperiod and lid suture on eye grow th in chickens显示文摘 | Osol G Schw artz B Foss DC | 1986 | Invest Ophthalmol Vis Sci1986，27，2： | 1 |
| 11 | Effects of time ,photoperiod ,and pinealectomy on ocular and plasma melatonin concentrations in the chick 显示文摘 | OSOL G SCHWARTZ B FOSS D C | 1985 | Gen Comp Endocrinol1985，58，3： | 1 |
| 12 | Follicular shuttling of marginal zone B cells facilitates antigen transport显示文摘 | Cinamon G Zachariah MA Lain OM Foss FW Jr Cyster JG | 2008 | Nat Immunol2008，9，1： | 1 |
| 13 | Optimization of method for detecting and characterizing NOM by HPLC-size exclusion chromatography with UV and on-line DOC detection显示文摘 | Amy G Foss D | 2002 | Environ Sci Technol2002，36，5： | 1 |
| 14 | Frequent expression of the B-cell-specific activator protein in Reed-Sternberg cell of classical Hodgkin's disease provides further evidence for its B-cell origin显示文摘 | Foss H Reusch R Demel G | 1999 | Blood1999，94，9： | 1 |
| 15 | Expression of vascular endothelial growth factor in lymphomas and Castleman's disease 显示文摘 | Foss HD Araujo I Demel G | 1997 | J Pathol1997，183，1： | 1 |
| 16 | Optimization of method for detecting and characterizing NOM by HPLC-size exclusion chromatography with UV and on-line DOC detection 显示文摘 | Her N Amy G Foss D | 2002 | Environmental Science & Technology2002，36，5： | 1 |
| 17 | Using professional specialty competencies to guide course development 显示文摘 | Foss G F Janken J K Langford D R | 2004 | J Nuts E-duc2004，43，8： | 1 |
| 18 | Thick etch-through macroporous Si membrane from p-and n-Si, and fast pore etching and tuning the pore size from n-Si 显示文摘 | Kan P Y Y Foss S E Finstad T G | 2007 | Materials Science and Engineering B-Solid State Materials for Advanced Technology2007，137，13： | 1 |
| 19 | Expression of vascular endothelial growth factor in lymphomas and Castleman's disease显示文摘 | Foss HD Araujo I Demel G | 1997 | J Pathol1997，183，： | 1 |
| 20 | Template-synthesized nanoscopic goldparticle:optical spectra and the effects of particle显示文摘 | FOSS C A Jr HORNYAK G L STOCKERT J A MARTIN C R | 1994 | J Phys Chem1994，98，11： | 1 |
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