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| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | Pathophysiologic correlates of acute porcine pleuropneumonia显示文摘 | Baarsch M J Foss D L Murtaugh M P | 2000 | Am J Vet Res2000，61，： | 1 |
| 3 | miR-1254 and miR-574-5p: serum-based microRNA biomarkers for early-stage non-small cell lung cancer显示文摘 | Foss K M Sima C Ugolini D | 2011 | J Thorac Oneol2011，6，： | 1 |
| 4 | Pathways of organic carbon oxidation in three continental margin sediments 显示文摘 | Canfield D E J? rgensen B B Fossing H | 1993 | Marine Geology1993，113，： | 1 |
| 5 | Using professional specialty competencies to guide course development 显示文摘 | Foss G F Janken J K Langford D R | 2004 | Journal of Nursing Educa- tion2004，43，8： | 1 |
| 6 | Tumor necrosis factor receptor-associated factor 1 is overexpressed in Reed-Stemberg cells of Hodgkin's disease and Epstein-Barr virus-transformed lymphoid cells 显示文摘 | Foss H D Demel G | 1999 | Blood1999，93，2： | 1 |
| 7 | Bone density, osteoarthrosis of the hip and fracture of the upper end of the femur 显示文摘 | FOSS M V BYERS P D | 1972 | Ann Rheum Dis1972，31，： | 1 |
| 8 | Dynamic line rating in the operating environment显示文摘 | Foss S D Maraio R A | | 0，，： | 1 |
| 9 | Intrathecal neostig-mine and sufentanil for early labor analgesia显示文摘 | Nelson KE D'Angelo R Foss ML et a1 | | 0，，91： | 1 |
| 10 | Pathways oforganic carbon oxidation in three continental margin sedi- ments显示文摘 | Canfield D E Jorgensen B B Fossing H | 1993 | Mar Geol1993，113，： | 1 |
| 11 | Eval- uation and development of a novel binocular treatment (I-BiT) system using video clips and interactive games to improve vision in children with amblyopia: study protocol for a randomised controlled trial显示文摘 | Foss A J Gregson R M MacKeith D | 2013 | Trials2013，14，1： | 1 |
| 12 | Gated importation of prothymocytes by adult mouse thymus is coordinated with their periodic mobilization from bone marrow显示文摘 | Donskoy E Foss D Goldschneider I | 2003 | J Immunol2003，171，7： | 1 |
| 13 | Estrogen and progesterone receptors in salivary gland adenoid cystic carcinoma显示文摘 | Shick P C Riordan G P Foss R D | 1995 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod1995，80，4： | 1 |
| 14 | Synthesis and biological evaluation of c-aminophosphonates as potent, subtype-selectivesphingosine 1-phosphate receptor qagonists and antagonists 显示文摘 | Frank W Foss Jr Ashley H Snyder Michael D Davis | 2007 | Bioorg Med Chem2007，15，2： | 1 |
| 15 | Pathways of organic carbon oxidation in three continental margin sediments显示文摘 | Canfield D E Jorgensen B B Fossing H | 1993 | Marine Geology1993，113，12： | 1 |
| 16 | Effects of time ,photoperiod ,and pinealectomy on ocular and plasma melatonin concentrations in the chick 显示文摘 | OSOL G SCHWARTZ B FOSS D C | 1985 | Gen Comp Endocrinol1985，58，3： | 1 |
| 17 | Differential regulation of macrophage interleukin-1 (IL-1),IL-12,and CD80-CD86 by two bacterial toxins显示文摘 | Zilliox M J Murtaugh M P | 1999 | Infect Immun1999，67，10： | 1 |
| 18 | Optimization of method for detecting and characterizing NOM by HPLC-size exclusion chromatography with UV and on-line DOC detection显示文摘 | Amy G Foss D | 2002 | Environ Sci Technol2002，36，5： | 1 |
| 19 | Use of protective equipment by in-line skaters : an observational study 显示文摘 | Beimess D J Foss RD Desmond KJ | 2001 | lnj Prey2001，1，： | 1 |
| 20 | Adjuvant danger signals increase the immune response to porcine reproductive and respiratory syndrome virus显示文摘 | Foss D L Zilliox M J Meier W et ai | 2002 | Viral Immunol2002，15，4： | 1 |
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