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| 1 | Endoscopic anti-reflux therapy for gastroesophageal reflux disease显示文摘Gastroesophageal reflux disease has an increasing incidence and prevalence worldwide.A significant proportion of patients have a suboptimal response to proton pump inhibitors or are unwilling to take lifelong medication due to concerns about long-term adverse effects.Endoscopic anti-reflux therapies offer a minimally invasive option for patients unwilling to undergo surgical treatment or take lifelong medication.The best candidates are those with a good response to proton pump inhibitors and without a significant sliding hiatal hernia.Transoral incisionless fundoplication and nonablative radiofrequency are the techniques with the largest body of evidence and that have been tested in several randomized clinical trials.Band-assisted ligation techniques,anti-reflux mucosectomy,antireflux mucosal ablation,and new plication devices have yielded promising results in recent noncontrolled studies.Nonetheless,the role of endoscopic procedures remains controversial due to limited long-term and comparative data,and no consensus exists in current clinical guidelines.This review provides an updated summary focused on the patient selection,technical details,clinical success,and safety of current and future endoscopic anti-reflux techniques. | Enrique Rodríguez de Santiago Eduardo Albéniz Fermin Estremera-Arevalo Carlos Teruel Sanchez-Vegazo Vicente Lorenzo-Zúñiga | 2021 | World Journal of Gastroenterology2021，27，39： | 9 |
| 2 | New Framework Based on Fusion Information from Multiple Landslide Data Sources and 3D Visualization显示文摘Recent monitoring techniques employ multiple sources of information for the characterization of the phenomenon to be studied, being the coupling and adjustment of multi-source data one of the first challenges to consider and solve. The authors propose a new framework of the multi-source and multi-temporal data-oriented fusion for the characterization of landslide events. The main objective is to generate 3D virtual models(in the form of dense point clouds) and feed them back with the characteristic of soil and subsoil information. The scheme consists of three main steps. The first one is on-site data collection(geological characterization, geophysical measurements, GPS measurements, and UAV/drone mapping). The second step is generation of a high-resolution 3D virtual model(~1-inch spatial resolution) from the frames acquired through the UAV using the structure of motion(SfM) processing;the developed virtual model is optimized with GPS measurements to minimize geolocation error and eliminate distortions. The last step is assembling of the acquired data in the field and densified point cloud considering the different nature of the data, re-escalating procedure and the information stacking layer. | Fermin Villalpando Jose Tuxpan Jose Alfredo Ramos-Leal Simon Carranco-Lozada | 2020 | Journal of Earth Science2020，31，1： | 6 |
| 3 | Multiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeutics显示文摘Multiple myeloma is a hematological malignancy inwhich clonal plasma cells proliferate and accumulate within the bone marrow. The presence of osteolytic le-sions due to increased osteoclast(OC) activity and sup-pressed osteoblast(OB) function is characteristic of the disease. The bone marrow mesenchymal stromal cells(MSCs) play a critical role in multiple myeloma patho-physiology, greatly promoting the growth, survival, drug resistance and migration of myeloma cells. Here, we specifically discuss on the relative contribution of MSCs to the pathophysiology of osteolytic lesions in light of the current knowledge of the biology of my-eloma bone disease(MBD), together with the reported genomic, functional and gene expression differences between MSCs derived from myeloma patients(pMSCs) and their healthy counterparts(dMSCs). Being MSCs the progenitors of OBs, pMSCs primarily contribute to the pathogenesis of MBD because of their reduced osteogenic potential consequence of multiple OB inhibi-tory factors and direct interactions with myeloma cells in the bone marrow. Importantly, pMSCs also readily contribute to MBD by promoting OC formation and ac-tivity at various levels(i.e., increasing RANKL to OPG expression, augmenting secretion of activin A, uncou-pling ephrinB2-EphB4 signaling, and through augment-ed production of Wnt5a), thus further contributing to OB/OC uncoupling in osteolytic lesions. In this review, we also look over main signaling pathways involved in the osteogenic differentiation of MSCs and/or OB activity, highlighting amenable therapeutic targets; in parallel, the reported activity of bone-anabolic agents(at preclinical or clinical stage) targeting those signaling pathways is commented. | Antonio Garcia-Gomez Fermin Sanchez-Guijo M Consuelo del Caizo Jesus F San Miguel Mercedes Garayoa | 2014 | World Journal of Stem Cells2014，6，3： | 5 |
| 4 | Down-regulation of cell surface CXCR4 by HIV-1 显示文摘 | Choi B Gatti PJ Fermin CD | 2008 | Virol J2008，5，： | 1 |
| 5 | Design of ultra-wideband substrate integrated waveguide(SIW) filters in zigzag topology显示文摘 | Fermin mira jordi mateu Santiago cogollos Vicente E.boria | | 0，，05： | 1 |
| 6 | Efferent Vagal Nerve Stimulation Attenuates Gut Barrier Injury After Burn: Modulation of Intestinal Occludin Expression显示文摘 | Todd W. Costantini Vishal Bansal Carrie Y. Peterson William H. Loomis James G. Putnam Fermin Rankin Paul Wolf Brian P. Eliceiri Andrew Baird Raul Coimbra | 2010 | The Journal of Trauma: Injury Infection and Critical Care2010，，6： | 1 |
| 7 | SJES14121200034975显示文摘 | Kenneth Cusi Zhi Chang Steve Harrison Romina Lomonaco Fernando Bril Beverly Orsak Carolina Ortiz-Lopez Joan Hecht Ariel E. Feldstein Amy Webb Christopher Louden Martin Goros Fermin Tio | 2014 | Journal of Hepatology2014，，1： | 1 |
| 8 | Region growing with pulse-coupled neural networks: an alternative to seeded re-gion growing 显示文摘 | Stewart R D Fermin I Opper M | 2002 | IEEE Transactions on Neural Networks2002，13，6： | 1 |
| 9 | Evidence for model- based action planning in a sequential finger movement task显示文摘 | FERMIN A YOSHIDA T ITO M | 2010 | J Motor Behavior2010，42，6： | 1 |
| 10 | Region growing with pulse-coupled neural networks: an alternative to seeded region grow- ing 显示文摘 | STEWART R D FERMIN I OPPER M | 2002 | IEEE Transactions on Neural Network2002，13，6： | 1 |
| 11 | Region growing with pulse-coupled neural networks: an alternative to seeded region growing 显示文摘 | Stewart Robert D Fermin Iris Opper Manfred | 2002 | IEEE Trans Neural Networks2002，13，6： | 1 |
| 12 | In-stent restenosis:contributions of inflammatory responses and arterial injury to neointimal hyperplasia显示文摘 | Kornowski R Hong M Fermin F | 1998 | J Am Coll Cardiol1998，31，1： | 1 |
| 13 | Serum alanine aminotransferase predicts interventricular septum thickness and left ventricular mass in patients with nonalcoholic fatty liver disease显示文摘 | Juan Ybarra Sandra Fernández Joan Sánchez-Hernández June H. Romeo Carlos Ballesta-Lopez Javier Guell Fermin Mearin | 2014 | European Journal of Gastroenterology & Hepatology2014，，6： | 1 |
| 14 | Finite volume solvers and moving least-squares approximations for the compressible Navier-Stokes equations on unstructured grids显示文摘 | Cueto-Felgueroso L Colominas I Fermin N | | 0，，45： | 1 |
| 15 | Significance of nanophytoplankton photosynthesis and primary production in a coastal upwelling system (R a de Vigo, NW Spain) 显示文摘 | TILSTONE G H FIGUEIRAS F G FERMIN E G | 1999 | Marine Ecology Progress Series1999，183，： | 1 |
| 16 | 铈对Ti-V-Cr-Fe储氢合金显微组织的影响显示文摘使用V-Fe合金为原料制备了Ti24.93V31.17Cr37.40Fe6.50Cex固溶体储氢合金,采用EPMA和XRD对合金显微组织和相结构进行了分析。结果表明,不含Ce的Ti24.93V31.17Cr37.40Fe6.50合金由BCC主相和分布于晶界的Ti9.7Fe3.3O3和TiO0.325相组成。当Ce添加于合金后,随着合金中Ce含量的增加,Ti9.7Fe3.3O3和TiO0.325相含量明显减少。Ce的添加抑制了富Ti相的析出,促进了合金元素尤其是Ti的均匀分布。此外,随Ce含量增加,合金BCC主相平均原子半径和晶格常数随之增大,有利于增大合金的储氢容量。 | 黄倬 Fermin Cuevas 刘晓鹏 蒋利军 Michel Latroche E. Leroy 杜军 | 2009 | 中国稀土学报2009，27，1： | 1 |
| 17 | Papaya ringspot virus resistance of transgenic rainbow and sunup is affected by gene dosage,plant development,and coat protein homology显示文摘 | ENNANT P FERMIN G FITICH M M | 2001 | European Journal of Plant Pathology2001，107，： | 1 |
| 18 | Universal and Reconfigurable to UPS Active Power Filter for Line Conditioning显示文摘 | FERMIN B SALVADOR M FERNANDO Y | | 0，，01： | 1 |
| 19 | Comparison of pre-reducing agents for antimony determination by hydride generation atomic fluorescence spectrometry显示文摘 | Ricard Miravet Jose Fermin Lopez-Sanehez Roser Rubio | 2004 | Anal Chim Acta2004，511，2： | 1 |
| 20 | Binding of the promen fluorescent probe to human serum albumin:a fluorescence spectroscopic study显示文摘 | Fermin Moreno | 1999 | Chemico-Biological Interaction1999，121，： | 1 |
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