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| 1 | Starting glargine in insulin-nave type 2 diabetic patients based on body mass index is safe显示文摘AIM:To evaluate the safety of four insulin titration algorithms in a homogeneous population of insulin-na ve type 2 diabetic patients.METHODS:We conducted a 24-wk,open,single-center study with 92 insulin-na ve type 2 diabetes patients who failed treatment with one or two oral drugs.The patients were randomized to one of the four following algorithms:LANMET(n=26)and LANMET PLUS(n=22)algorithms,whose patients received a fixed initial insulin dose of 10 U,and DeGold(n=23)and DeGold PLUS(n=21)algorithms,whose patients’initial insulin dose was based on their body mass index(BMI).In addition,patients in the PLUS groups had their insulin titrated twice a week from 2 to 8 U.In the other two groups,the titration was also performed also twice a week,but in a fixed increments of 2 U.The target fasting glucose levels for both groups was 100 mg/dL.RESULTS:There was no significant difference in efficacy parameters.There was no significant difference when comparing moderate hypoglycemia events in algorithms starting with a 10 U fixed dose and algorithms based on BMI.However,there was a significant increase in moderate hypoglycemia events among the PLUS treated patients when the LANMET and DeGold algorithms were compared with the 2 fast-titration PLUS algorithms.We observed 12 hypoglycemia events in the first group,which corresponded to 0.94 events/patient per year,and we observed 42 events in the second group,which corresponded to 2.81 events/patient per year(P<0.037).No further significant differences were observed when other comparisons between the algorithms were carried out.CONCLUSION:Starting insulin glargine based on BMI is safe,but fast titration algorithms increase the risk of moderate hypoglycemia. | Denise R Franco Juliana Baptista Fatima RM Abreu Risoneide B Batista Freddy G Eliaschewitz | 2014 | World Journal of Diabetes2014，5，1： | 2 |
| 2 | Outcomes of submucosal(T1b) esophageal adenocarcinomas removed by endoscopic mucosal resection显示文摘AIM To investigate the outcomes and recurrences of p T1 b esophageal adenocarcinoma(EAC) following endoscopic mucosal resection(EMR) and associated treatments.METHODS Patients undergoing EMR with pathologically confirmed T1 b EAC at two academic referral centers were retrospectively identified.Patients were divided into 4 groups based on treatment following EMR:Endoscopic therapy alone(group A),endoscopic therapy with either chemotherapy,radiation or both(group B),surgicalresection(group C) or no further treatment/lost to follow-up(<12 mo)(group D).Pathology specimens were reviewed by a central pathologist.Follow-up data was obtained from the academic centers,primary care physicians and/or referring physicians.Univariate analysis was performed to identify factors predicting recurrence of EAC.RESULTS Fifty-three patients with T1 b EAC underwent EMR,of which 32(60%) had adequate follow-up ≥ 12 mo(median 34 mo,range 12-103).There were 16 patients in group A,9 in group B,7 in group C and 21 in group D.Median follow-up in groups A to C was 34 mo(range 12-103).Recurrent EAC developed overall in 9 patients(28%) including 6(38%) in group A(median:21 mo,range:6-73),1(11%) in group B(median:30 mo,range:30-30) and 2(29%) in group C(median 21 mo,range:7-35.Six of 9 recurrences were local;of the 6 recurrences,5 were treated with endoscopy alone.No predictors of recurrence of EAC were identified.CONCLUSION Endoscopic therapy of T1 b EAC may be a reasonable strategy for a subset of patients including those either refusing or medically unfit for esophagectomy. | Darren D Ballard Neel Choksi Jingmei Lin Eun-Young Choi B Joseph Elmunzer Henry Appelman Douglas K Rex Hala Fatima William Kessler John M DeWitt | 2016 | World Journal of Gastrointestinal Endoscopy2016，8，20： | 2 |
| 3 | Pancreaticobiliary and duode- nal perforations after periampullary endoscopic proce- dures : diagnosis and management显示文摘 | Fatima J Baron T H Topazian M D Houghton S G Iqbal C W Ott B J | 2007 | Arch Surg2007，142，： | 1 |
| 4 | Path Planning of Mobile Robot Based on Modification of Vector Field Histogram using Neuro-- Fuzzy Algorithm 显示文摘 | All H Hamad Fatima B Ibrahim | 2010 | International Journal of Advancements in Computing Technology2010，2，3： | 1 |
| 5 | Modification of the molar anionic charge density of acetone-formaldehyde-sulfite dispersant to improve adsorption behavior and effectiveness in the presence of cement fluid loss polymer 显示文摘 | Plank J Fatima D B Nils Recalde L | 2009 | Journal of Applied Polymer Science2009，111，4： | 1 |
| 6 | Microbical contamination of stored hydrocarbon fuels and its control显示文摘 | CHRISTINE C G FATIMA M B JOAN K | 2003 | Journal of Microbiology2003，32，4： | 1 |
| 7 | Adsorption of Direct Red 2 on bentonite modified by cetyltrimethylammonium bromide 显示文摘 | Zohra B Aicha K Fatima S | 2008 | Chemical Engineering Journal2008，136，23： | 1 |
| 8 | Pollen parent enhances fruit size and quality in intervarietal crosses in guava (Psidium guajava)显示文摘 | Usman M Samad W A Fatima B | | 0，，1： | 1 |
| 9 | Extracellular invertase is an essential component of cytokinnin-mediated delay of senescence显示文摘 | LARA M E B GARCIA M C G FATIMA T | 2004 | The Plant Ce112004，16，： | 1 |
| 10 | Green chemistry ap- proaches to the synthesis of 5-Alkoxycarbonyl-4-aryl-3,4- dihydropyrimidin-2 (1H)-ones by a three-component cou- pling of one-pot condensation reaction: Comparison of ethanol, water, and solvent-free conditions 显示文摘 | Bose D S Fatima L Mereyala H B | 2003 | Journal of Organic Chemistry2003，68，2： | 1 |
| 11 | Antimicrobial susceptibili- ty pattern of clinical isolates of Pseudomonas aeruginosa isolat- ed from patients of lower respiratory tract infections显示文摘 | Fatima A Naqvi S B Khaliq S A | 2012 | Spring- erplus2012，1，1： | 1 |
| 12 | Shelf life of shrimp (Penaeus merguiensis) stored in ice and partially frozen显示文摘 | Fatima R Khan M A Qadri R B | 1988 | J Sci Food Agric1988，42，： | 1 |
| 13 | Green chemistry approaches to the synthesis of 5-alkoxycarbonyl-4-aryl-3,4- dihydropyrimidine-2 (1 H)-ones by a three-component coupling of one-pot condensation reaction : comparson of ethanol, wa- ter and solvent-free conditions显示文摘 | BOSE D S FATIMA L MEREYALA H B | 2002 | J Org Chem2002，68，： | 1 |
| 14 | Serrated polyps of the colon: how reproducible is their classification?显示文摘 | Arzu Ensari Banu Bilezik?i Fatima Carneiro Gülen Bülbül Do?usoy Ann Driessen Ay?e Dursun Jean-Fran?ois Flejou Karel Geboes Gert de Hertogh Anne Jouret-Mourin Cord Langner Ir?s D. Nagtegaal Johan Offerhaus Janina Orlowska Ari Ristim?ki Julian Sanz-Ortega B | 2012 | Virchows Archiv2012，，5： | 1 |
| 15 | Native-like tertiary struc- ture in the Mucor miehei lipase molten globule state ob- tained at low pH 显示文摘 | Fatima S Ahmad B Khan R H | 2007 | IUBMB Life2007，59，3： | 1 |
| 16 | Focussed Microwave - assisted Sample Preparation: Total Phenol Determination in Petroleum Refinery Effluents by Flow Injection Spectrophotometry 显示文摘 | Maria Cristina B Quaresma Ricardo J Cassella Mariade Fatima B | 2004 | Microchemical Journal2004，78，1： | 1 |
| 17 | Success of Trichogramma chilonis (Ishii) for area-wide control of sugarcane borers in Pakistan显示文摘 | Ashraf M Fatima B | 1996 | British Crop Protection Council1996，，1： | 1 |
| 18 | Label-free global serum proteomic profiling reveals novel celecoxib-modulated proteins in familial adenomatous polyposis patients显示文摘 | Fatima N Chelius D Luke B T | 2009 | Cancer Genomics Proteomics2009，6，1： | 1 |
| 19 | Characterization and effect of edible coatings on minimally processed garlic quality显示文摘 | MAIA E R FATIMA F S N ALVARENGA B D | 2008 | Carbohydrate Polymers2008，72，3： | 1 |
| 20 | Development of a chemically modified electrode based on carbon paste and functionalized silica gel for preconcentration and voltammetric determination of mercury (Ⅱ)显示文摘 | ALEIXO L M DE FATIMA M SOUZA B | 1993 | Analytica Chimica Acta1993，271，1： | 1 |
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