|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Vascular endothelial growth factor gene polymorphisms in North Indian patients with recurrent miscarriages显示文摘 | Shagun Aggarwal Farah Parveen Rehan Mujeeb Faridi Shubha Phadke Minal Borkar Suraksha Agrawal | 2010 | Reproductive BioMedicine Online2010，，： | 2 |
| 2 | Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide显示文摘The amyloid aggregation of peptides and proteins is a hallmark of neurological disorders and type 2 diabetes.Human islet amyloid polypeptide(IAPP),co-secreted with insulin by pancreaticβ-cells,plays dual roles in both glycemic control and the pathology of type 2 diabetes.While IAPP can activate the NLRP3 inflammasome and modulate cellular autophagy,apoptosis and extracellular matrix metabolism,no data is available concerning intracellular protein expression upon exposure to the polypeptide.More surprisingly,how intracellular protein expression is modulated by nanoparticle inhibitors of protein aggregation remains entirely unknown.In this study,we first examined the changing proteomes ofβTC6,a pancreaticβ-cell line,upon exposure to monomeric,oligomeric and fibrillar IAPP,and detailed cellular protein expression rescued by graphene quantum dots(GQDs),an IAPP inhibitor.We found that 29 proteins were significantly dysregulated by the IAPP species,while majority of these proteins were nucleotide-binding proteins.Collectively,our liquid chromatography tandem-mass spectrometry,fluorescence quenching,helium ion microscopy,cytotoxicity and discreet molecular dynamics simulations data revealed a remarkable capacity of GQDs in regulating aberrant protein expression through H-bonding and hydrophobic interactions,pointing to nanomedicine as a new frontier against human amyloid diseases. | Ava Faridi Yunxiang Sun Monika Mortimer Ritchlynn R.Aranha Aparna Nandakumar Yuhuan Li Ibrahim Javed Aleksandr Kakinen Qingqing Fan Anthony W.Purcell Thomas P.Davis Feng Ding Pouya Faridi Pu Chun Ke | 2019 | Nano Research2019，12，11： | 2 |
| 3 | Killer immunoglobulin-like receptors (KIRs) and HLA-C allorecognition patterns implicative of domi- nant activation of natural killer cells contribute to recurrent mis- carriages 显示文摘 | Faridi RM Agrawal S | 2011 | Hum Reprod2011，26，2： | 1 |
| 4 | Long-term follow-up and prognostic significance of angiogenic basic fibroblast growth factor (bFGF) expression in patients with breast cancer显示文摘 | Faridi A Rudlowski C Biesterfeld S | 2002 | Pathol Res Pract2002，198，1： | 1 |
| 5 | Stress and protective factors in individuals at ultra-high risk for psychosis,first episode psychosis and healthy controls显示文摘 | Pruessner M Srividya Nr Faridi K | 2011 | Schizophrenia Research2011，129，1： | 1 |
| 6 | Oncogenic potential of Human Papillomavirus (HPV) and its relation with cervical cancer显示文摘 | Faridi R Zahra A Khan K Idrees M | | 0，，： | 1 |
| 7 | Antimicrobial potential of Glycyrrhiza glabra roots 显示文摘 | Gupta V K Fatima A Faridi U | 2008 | J Ethnopharmacol2008，，116： | 1 |
| 8 | Synthesis of chalcone derivatives on steroidal framework and their anticancer activities显示文摘 | Saxena H O Faridi U Kumar J | | 0，，13： | 1 |
| 9 | Interleukin-1 gene cluster variants and recurrent pregnancy loss among North Indian women :retrospective study and meta-analysis 显示文摘 | Agrawal S Parveen F Faridi RM | 2012 | Re- prod BioMed Online2012，24，3： | 1 |
| 10 | In situ hybridization of ribosomal DNA to rose chromosomes显示文摘 | Ma Y Islam - Faridi M N Crane C F | 1997 | Journal of Heredity1997，88，2： | 1 |
| 11 | BCG vaccination reac-tion in low birth weight infants显示文摘 | Kaur S Faridi MM Agarwal KN | 2002 | Indian J Med Res2002，116，： | 1 |
| 12 | A prospective study ofironstatus in exclusively breastfed term infants up to6months of age显示文摘 | Raj S Faridi M Rusia U | 2008 | Int Breastfeed J2008，3，1： | 1 |
| 13 | Synthesis of chal- cone derivatives on steroidal framework and their antican- cer activities显示文摘 | Saxena HO Faridi U Kumar JK | 2007 | Steroids2007，72，13： | 1 |
| 14 | HELLP syndrome 显示文摘 | Rrath W Faridi A Dudenhausen JW | 2000 | J Perinat Med2000，28，4： | 1 |
| 15 | Long-term follow-up and prog- nosis significance of angiogenic basic fibroblast growth factor (bFGF)ex- pression in patients with breast cancer 显示文摘 | Faridi A Rudlowski C Biesterfeld S | 2002 | Pathol Res Pract2002，198，1： | 1 |
| 16 | A new look at flux-free ultrasonic soldering显示文摘 | FARIDI H R DEVLETIAN J H LE H P | 2000 | Welding Journal2000，79，9： | 1 |
| 17 | Polypyrrole and Polypyrrole-tungstate Electropolymerization Coatings on Carbon Steel and Evaluating Their Corrosion Protection Performance via Electrochemical Impedance Spectroscopy 显示文摘 | Sabouri M Shahrabi T Faridi H R | 2009 | Prog Org Coat2009，64，4： | 1 |
| 18 | Proteomics indicates modulation of tubulin polymerization by L-menthol inhibiting human epithelial colorectal adenocarcinoma cell proliferation显示文摘 | Faridi U Sisodia B S Shukla A K | 2011 | Proteomics2011，11，10： | 1 |
| 19 | Primary angiosarcoma of breast 显示文摘 | Haroon S Faridi N Lodhi FR | 2013 | J Coll Physicians Surg Pak2013，23，5： | 1 |
| 20 | Oncogenic potential of Human papillomavirus(HPV)and its relation with cervical cancer显示文摘 | Faridi R Zahra A Khan K | 2011 | Virol J2011，8，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员