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| 1 | Immunological aspects of liver cell transplantation显示文摘Within the field of regenerative medicine, the liver is of major interest for adoption of regenerative strategies due to its well-known and unique regenerative capacity. Whereas therapeutic strategies such as liver resection and orthotopic liver transplantation(OLT) can be considered standards of care for the treatment of a variety of liver diseases, the concept of liver cell transplantation(LCTx) still awaits clinical breakthrough. Success of LCTx is hampered by insufficient engraftment/long-term acceptance of cellular allografts mainly due to rejection of transplanted cells. This is in contrast to the results achieved for OLT where longterm graft survival is observed on a regular basis and, hence, the liver has been deemed an immuneprivileged organ. Immune responses induced by isolated hepatocytes apparently differ considerably from those observed following transplantation of solid organs and, thus, LCTx requires refined immunological strategies to improve its clinical outcome. In addition, clinical usage of LCTx but also related basic research efforts are hindered by the limited availability of high quality liver cells, strongly emphasizing the need for alternative cell sources. This review focuses on the various immunological aspects of LCTx summarizing data available not only for hepatocyte transplantation but also for transplantation of non-parenchymal liver cells and liver stem cells. | Felix Oldhafer Michael Bock Christine S Falk Florian WR Vondran | 2016 | World Journal of Transplantation2016,6,1: | 3 |
| 2 | 类固体非晶态材料的变形与失效显示文摘自20世纪70年代以来,类固体非晶态材料变形与失效的理论模型相继出现,这些模型基于应力驱动分子重排从而在局部流动缺陷处发生剪切转变这一物理图像.该图像是现代剪切转变区理论的基础,也是本综述的焦点.我们将首先概述该理论框架并给出一些应用案例,特别是块体金属玻璃应力−应变测量结果的阐释,剪切带数值模拟分析和剪切转变区运动方程在自由边界计算中的应用.在本综述的第二部分,为简单起见,将关注非晶塑性的非热模型,并基于该模型说明剪切转变区理论是如何从非平衡热力学的系统描述中发展起来的. | Falk M L Langer J S 陈艳(译) 王云江(校) | 2021 | 力学进展2021,51,2: | 3 |
| 3 | Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032)显示文摘 | Fiona McPhee Amy K. Sheaffer Jacques Friborg Dennis Hernandez Paul Falk Guangzhi Zhai Steven Levine Susan Chaniewski Fei Yu Diana Barry Chaoqun Chen Min S. Lee Kathy Mosure Li-Qiang Sun Michael Sinz Nicholas A. Meanwell Richard J. Colonno Jay Knipe Paul S | 2012 | Antimicrobial Agents and Chemotherapy2012,,10: | 2 |
| 4 | Effect of composition and crystallization temperature on microstructure of Y and Er-SiAlON Iw-phase glass-ceramics显示文摘 | MACLAREN I FALK L K L DIAZ A HAMPSHIRE S | 2001 | Journal of the American Ceramic Society2001,84,7: | 1 |
| 5 | Combined effects of noise and ototoxic drugs显示文摘 | Falk S A | 1972 | Environ Health Perspect1972,,2: | 1 |
| 6 | Interaction among nitric oxide,reactive oxygen species, and antioxidants during endotoxemia - related acute renal failure显示文摘 | Wang W Jittikanont S Falk SA | 2003 | Am J Physiol Renal Physiol2003,284,: | 1 |
| 7 | Pigment epithelium derived factor (PEDF) is neuroprotective in two in vitro models of Parkinson's diseases显示文摘 | Falk T Zhang S Sherman SJ | 2009 | Neurosci Lett2009,458,2: | 1 |
| 8 | Signs and symptoms of urethritis and cervicitis among women with or without coplasma genitlium or Chlamydia traehomatis infection 显示文摘 | Falk L Fredund H Jensen S | 2005 | Sex Transm Infect2005,81,1: | 1 |
| 9 | Systemic chemothera- py with or without eetuximab in patients with reseetable eoloreetal liver metastasis: the New EPOC randomised con- trolled trial显示文摘 | Primrose J Falk S Finch-Jones M | 2014 | Lancet Oncol2014,15,6: | 1 |
| 10 | Effect of composition on crystallization of Y/Yb-Si-Al-O-N B-phase glasses显示文摘 | MENKE Y HAMPSHIRE S FALK L K L | 2007 | Journal of the American Ceramic Society2007,90,5: | 1 |
| 11 | Vascular endothelial growth factor B (VEGF-B) is up-regulated and exogenous VEGF-B is neuroprotective in a culture model of Parkinson' s disease 显示文摘 | Falk T Zhang S Sherman SJ | 2009 | Mol Neurodegener2009,4,: | 1 |
| 12 | Human interleukin-3receptor modulates bcl-2 mma and protein levels through pro-tein kinase c in tf-1 cells显示文摘 | Rinaudo M S Su K Falk L A | 1995 | Blood1995,86,: | 1 |
| 13 | Timing of Surgery after long- coupe neoadjuvant chemoradiotherapy for rectal cancer: a systematic review of the literature显示文摘 | Foster J D Jones E L Falk S | 2013 | Dis Colon Rectum2013,56,7: | 1 |
| 14 | Parvovirus B19 DNA in kidney tissue of patients with focal segmental glomeruloselerosis 显示文摘 | Tanawattanacharoen S Falk RJ Jennette JC | 2000 | Am J Kidney Dis2000,35,: | 1 |
| 15 | CONVERT : concurrent once - daily versus twice - daily radiotherapy - a new phase HI random- ized controlled trial for patients with limited - stage small cell lung cancer and good performance status 显示文摘 | Faivre - Finn C Falk S | 2009 | Lung Cancer2009,63,2: | 1 |
| 16 | Isolation,genetic and functional characterization of novel soil nirK-type denitrifiers 显示文摘 | Falk S Liu B Braker G | 2010 | Syst Appl Microbiol2010,33,6: | 1 |
| 17 | Cardiac disease in chronic obstructive pulmonary disease显示文摘 | Falk JA Kadiev S Criner GJ | | 0,,: | 1 |
| 18 | Promotions and incentives: the case of multistage elimination tournaments显示文摘 | Altmann S Falk A and Wibral M | 2012 | Journal of Labor Economics2012,30,1: | 1 |
| 19 | Exact prediction of a natural T cell epitope显示文摘 | Rotzschke O Falk K Stevanovic S | 1991 | Eur J Immunol1991,21,11: | 1 |
| 20 | Littoral cell angioma显示文摘 | Falk S Stutte H J Frizzear G | 1991 | Am J Surg Pathol1991,15,11: | 1 |