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96篇 您的检索式:作者名="Colonno"
    题名 作者 年代 出处 被引量
1Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032)显示文摘Fiona McPhee Amy K. Sheaffer Jacques Friborg Dennis Hernandez Paul Falk Guangzhi Zhai Steven Levine Susan Chaniewski Fei Yu Diana Barry Chaoqun Chen Min S. Lee Kathy Mosure Li-Qiang Sun Michael Sinz Nicholas A. Meanwell Richard J. Colonno Jay Knipe Paul S 2012Antimicrobial Agents and Chemotherapy2012,,10:2
2二次冠状动脉旁路移植术的临床疗效显示文摘目的评价二次冠状动脉旁路移植术的临床疗效。方法51例病人(占医院同期进行冠状动脉旁路移植术病人的2.5%)进行二次冠状动脉旁路移植术,距首次手术(15.1±5.8)年。10例采用非体外循环冠状动脉旁路移植术(OPCABG),41例采用体外循环冠状动脉旁路移植术(CABG)。正中切口43例,左胸侧切口8例。结果3例行CABG病人手术后呼吸衰竭,需呼吸机辅助。所有病人住ICU(2.2±0.7)天,住院(9.2±2.4)天。术后死亡2例(3.9%),采用OPCABG和CABG者各1例,死亡原因分别为急性心肌梗死、低心排血量综合征和呼吸功能衰竭、重症肺炎。完全再血管化44例,其中行OPCABG者6例,CABG者38例。部分再血管化7例,行OPCABG者4例,CABG者3例。结论CABG和OPCABG行二次冠状动脉旁路移植术均安全,疗效满意,能达到完全再血管化的目的。穆军升 张健群 Cloud Deville Colonno Giorgio 2010中华胸心血管外科杂志2010,,1:2
3Entecavir resistance is rare in nucleoside na? ve patients with hepatitis B显示文摘Colonno RJ Rose Batdick CI 2006Hepatology2006,44,:1
4Characterization of antiviral in transgenic mice expressing hepatitis B virus显示文摘Julander JG Colonno RJ Sidwell RW 2003Antiviral Res2003,59,3:1
5Assessment at three years shows high barrier to resistance is maintained in entecavir treated nueleoside naive patients while resistance emergence in creases over time in lamivudine refractory patients显示文摘Colonno RJ Rose RE Pokomowski K 2006Hepatology2006,44,41:1
6Ribavirin and mycophenolic acid markedly potentiate the anti-hepatitis B virus activity of entecavir显示文摘Ying C Colonno R Clercq ED 2007Antiviral Res2007,73,3:1
7Long-term entecavir treatment result in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection显示文摘Colonno RJ Genovesi EV Medina I 2001J Infect Dis2001,184,10:1
8Long-term entecavir treatment results in sustainedan tiviral eficacy and prolonged life span in the wood-chuck model of chronic hepatitis infection 显示文摘Colonno R J Genovesi EV Medina I 2001Infect Dis2001,184,10:1
9In vitro inhibition of hepadnavirus polymcrases by the triphosphates of BMS-200475and lobucavir显示文摘 Hamatake RK Colonno RJ 1998Antimicrob Agents Chemother1998,42,12:1
10Mechanistic characterization and molecular modeling of hepatitis B virus polymerase resistance to entecavir 显示文摘Walsh AW Langley DR Colonno RJ 2010PLoS One2010,5,2:1
11Emergence ofentecavir resistant hepatitis B virus after one year of therapy in phase Ⅱ&Ⅲ studies is only observed in lamivudine refractory patients显示文摘Colonno RJ Rose R Levine SM 2004Hepatology2004,4041,:1
12Characteri-zation of antiviral in transgenic mice expressing hepatitis B virus显示文摘Julander JG Colonno RJ Sidwell RW 2003Antiviral Res2003,59,3:1
13Antigenic conserva- tion and divergence between the viral-specific proteins of poliovir- us type 1 and various picornaviruses显示文摘Emini EA Schleif WA Colonno RJ 1985Virology1985,140,1:1
14In vitro inhibition of hepadnavirus polymerasas by the triphosphates of BMS_200475 and lobueavir显示文摘Seifer M Hamatake RK Colonno R J 1998Antimierob Agents Chemother1998,42,12:1
15In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir显示文摘Seifer M Hamatake RK Colonno RJ 1998Antimicrob Agents Chemother1998,42,12:1
16Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection显示文摘Colonno R J Genovesi EV Medina I 2001J Infect Dis2001,184,10:1
17In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir显示文摘SEIFER M HAMATAKE R K COLONNO R J 1998Antimicrob Agents Chemother1998,42,12:1
18Entecavir two year resistance update: no resistance observed in nucleoside naive patients and low frequency resistance emergence in lamivudine refractory patients 显示文摘Colonno RR Rose R Levine S 2005Hepatology2005,42,1:1
19Entecavir resistance is rare in nucleoside naive patients with hepatitis B 显示文摘Colonno R J Rose R Baldick C J 2006Hepatology2006,44,6:1
20In vitro inhibition of hepadnavirus polymerases by the triphosphates of BM8- 200475 and fobueavir显示文摘Seifer M Hamatake RK Colonno RJ 1998Antimicrob Agents Chemother1998,42,12:1
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