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| 1 | Early diagnosis and prediction of severity in acute pancreatitis using the urine trypsinogen-2 dipstick test:A prospective study显示文摘瞄准:评估量杆(Actim 胰腺炎) 在尖锐胰腺炎(AP ) 为严厉的早诊断和预言测试的 trypsinogen-2 的使用。方法:有 AP 的 92 个病人在这研究被包括。控制组是从非胰腺的原因有剧烈腹的疼痛的 25 个病人。尿 trypsinogen-2 量杆测试(UTDT ) 和常规诊断测试在所有病人被执行。病人们被亚特兰大分类作为有温和或严重的胰腺炎划分成二个组。结果:UTDT 是积极的在里面(94.6%)(8%) 87 AP 病人并且在二控制(P <
0.05 ) 。积极 UTDT 在 61 被发现(92.4%) 66 (71.7%) 有温和胰腺炎并且在所有(100%) 的病人 26 (28.3%) 与严重胰腺炎(P >
0.05 ) 。UTDT 确实在温和胰腺炎与那相比在严重胰腺炎更长持续了(6.2 +/- 2.5 d 对 2.0 +/- 1.43 d, P <
0.05 ) 。敏感,特性,积极预兆的价值,否定预兆的价值(NPV ) ,积极可能性比率(PLR ) 和 UTDT 的否定可能性比率(NLR ) 分别地是 91% , 72% , 96.6% , 70.4% , 3.4 和 0.1。结论:UTDT 是为承认上的使用的一个简单、快速、可靠的方法。它在 AP 为严厉的早诊断和预言有高特性和低 NLR。然而,它的相对低的 NPV 不允许 trypsinogen-2 量杆测试是为尖锐胰腺炎的诊断的一个独立工具;另外的常规诊断工具的使用仍然是一个要求。 | Erdinc Kamer Haluk Recai Unalp Hayrullah Derici Tugrul Tansug Mehmet Ali Onal | 2007 | World Journal of Gastroenterology2007，13，46： | 14 |
| 2 | Prognostic efficacy of inflammation-based markers in patients with curative colorectal cancer resection显示文摘AIM To evaluate the prognostic significance of neutrophilto-lymphocyte ratio(NLR), platelet-to-lymphocyte ratio(PLR), lymphocyte-to-monocyte ratio(LMR), and prognostic nutritional index(PNI) and other clinicopathological factors in patients undergoing curative resection of colon cancer.METHODS183 patients with histologically proven colorectal cancer who had undergone potentially curative resection between 2010 and 2016 at Ankara Numune Training and Research Hospital were retrospectively analyzed and clinicopathological characteristics included age, sex, tumor type, grade, size and localization, the number of metastatic and total number of lymph nodes removed, vascular and perineural invasion of the tumor, TNM stages, tumor marker levels(CEA, CA19-9, AFP, CA-125, CA15-3), complete blood counts, albumin levels, overall survival(months), NLR, PLR, LMR and PNI ratios were retrospectively reviewed and analyzed from the electronic database. The primary outcome measure was overall survival.RESULTS Regarding overall survival, on univariate analysis the following variables were significantly associated with poor outcome following resection: T-stage(P = 0.037), lymph node invasion(P = 0.037), cancer stage(P = 0.034), CEA(P = 0.042), CA19-9(P = 0.004), and PNI(P = 0.001). To evaluate the independent prognostic value, multivariate Cox proportional hazard analysis to control for other prognostic factors was used. Using cancer-specific death as an end point for NLR, PLR, LMR, PNI and CA19-9 the optimal cut off values were calculated by ROC analysis. Regarding overall survival, on multivariate analysis high CA19-9(HR = 1.001, 95%CI: 1.00-1.002, P = 0.012) and low PNI(HR = 0.938, 95%CI: 0.891-0.987, P = 0.014) were the only variables independently associated with shortened overall survival. Patients with a PNI < 35 had a median OS of 52.25 mo. In contrast, patients with an PNI > 35 had a median OS of 66 mo. Patients with a CA 19-9 < 17 had a median OS of 66 mo and in patients with a CA19-9 > 17 had a median OS of 53.76 mo.CONCLUSION This study shows that decrease in the PNI and increase in CA 19-9 is associated with poor survival in patients with resectable colon cancer. | özgür Akgül Erdinc Cetinkaya Metin Yalaza Sabri özden Mesut Tez | 2017 | World Journal of Gastrointestinal Oncology2017，9，7： | 11 |
| 3 | Same-day colonoscopy preparation with Senna alkaloids and bisacodyl tablets:A pilot study显示文摘AIM:To evaluate the efficacy of same-day bowel preparation with Senna alkaloids combined with bisacodyl tablets in routine colonoscopy procedures.METHODS:Between March and June 2013,a sameday bowel preparation was implemented in our endoscopy unit.The preparation consisted of a semi-liquid,fiber-free diet one day prior to the procedure,with two bisacodyl tablets after lunch and dinner,and 250 mL of Senna alkaloid with 1.5 L of drinking water at 6 am the day of the procedure.The quality control parameters of colonoscopy were evaluated and implemented according to the guidelines of the American Society for Gastrointestinal Endoscopy.The pre-procedure,duringprocedure and post-procedure patient data were collected and analyzed:(1) pre-procedure(age,gender,comorbid diseases,colonoscopy indications,complete lack of compliance with the bowel preparation protocol);(2) during-procedure(sedation dose,duration of colonoscopy,withdrawal time,cecal intubation rate,polyp detection rate,Boston Bowel Preparation Scores and presence of foam and clear liquid); and(3) postprocedure(visual analogue scale score,pain during the procedure,patient satisfaction and premature withdrawal due to the insufficient bowel preparation).RESULTS:A total of 75 patients were included in this study with a mean age of 54.64 ± 13.29 years; 53.3%(40/75) were female and 46.7%(35/75) were male.A complete lack of compliance with the bowel preparation protocol was seen in 6.7% of patients(5/75).The mean total duration of colonoscopy was 16.12 ± 6.51 min,and the mean withdrawal time was 8.89 ± 4.07 min.The cecal intubation rate was 93.8%(61/64) and the polyp detection rate was 40%(30/75).The mean Boston Bowel Preparation Score was 7.38 ± 1.81,with the following distribution:right colon,2.34 ± 0.89; transverse colon,2.52 ± 0.67; left colon,2.52 ± 0.63.The mean visual analogue scale score was 4.59 ± 1.57.Due to insufficient bowel preparation,seven patients(7/75; 9.3%) were asked to repeat the procedure.Of these,five patients had poor or modest compliance with the protocol,and two patients reported constipation.Premature withdrawal due to insufficient bowel preparation was 2.7%(2/75).The overall satisfaction with the protocol was 86.7%(65/75),with patients reporting they would prefer the same protocol in a repeat procedure.CONCLUSION:The same-day administration of Senna alkaloids appears to be a safe and effective bowel cleansing protocol for colonoscopy procedures. | Erdinc Yenidogan Ismail Okan Huseyin Ayhan Kayaoglu Gokhan Giray Akgul Mufit Sansal Servet Tali Zeki Ozsoy Mustafa Sahin | 2014 | World Journal of Gastroenterology2014，20，41： | 7 |
| 4 | Role of self expandable stents in management of colorectal cancers显示文摘Acute malignant colorectal obstruction is a complication of colorectal cancer that can occur in 7%-29% of patients. Self-expanding metallic stent placement for malignant colorectal obstruction has gained popularity as a safe and effective procedure for relieving obstruction. This technique can be used in the palliation of malignant colorectal obstruction, as a bridge to elective surgery for resectable colorectal cancers, palliation of extracolonic malignant obstruction, and for nonmalignant etiologies such as anastomotic strictures, Crohn's disease, radiation therapy, and diverticular diseases. Self-expanding metallic stent has its own advantages and disadvantages over the surgery in these indications. During the insertion of the self-expanding metallic stent, and in the followup, short term and long term morbidities should be kept in mind. The most important complications of the stents are perforation, stent obstruction, stent migration, and bleeding. Additionally, given the high risk of perforation, if a patient is treated or being considered fortreatmentwith antiangiogenic agents such as bevacizumab, it is not recommended to use self-expanding metallic stent as a palliative treatment for obstruction. Therefore, there is a need for careful clinical evaluation for each patient who is a candidate for this procedure. The purpose of this review was to evaluate self-expanding metallic stent in the management of the obstruction of the colon due to the colorectal and extracolonic obstruction. | erdinc cetinkaya ahmet bulent dogrul mehmet bulent tirnaksiz | 2016 | World Journal of Gastrointestinal Oncology2016，8，1： | 6 |
| 5 | Increased melatonin levels in aqueous humor of patients with proliferative retinopathy in type 2 diabetes mellitus显示文摘AIM: To report the association between melatonin levels in aqueous humor and serum, and diabetic retinopathy(DR) grade in type 2 diabetic patients.·METHODS: Aqueous humor and plasma samples from26 patients with DR(in nonproliferative and proliferative stages) and 14 control subjects were collected during cataract surgery after 6 p.m. Melatonin concentrations were determined using an enzyme-linked immunosorbent assay(ELISA).·RESULTS: Melatonin levels were significantly higher in the aqueous humor of patients with proliferative diabetic retinopathy(PDR) [18.57 ±2.67 pg/m L(range 15.20-23.06)vs 13.63±2.71 pg/m L(range 10.20-20.20), P =0.0001], but not in those with nonproliferative retinopathy(NPDR)[13.79±2.56 pg/m L(range 9.80-20.10) vs 13.63±2.71 pg/m L(range 10.20-20.20), P =0.961] compared to controls. There was decrement in the plasma melatonin level of patients with PDR, but no significant differences between the plasma melatonin levels of the study groups [ 5. 37 ±1.74 pg/m L(range 2.85-8.65) vs 6.11±1.90 pg/m L(range3.13-9.41), P =0.293], or between control and DR groups[NPDR 6.11 ±1.90 pg/m L(range 3.13-9.41) vs control6.15±1.91 pg/m L(range 2.18-9.86); PDR(5.37±1.74 pg/m L(range 2.85-8.65) vs control 6.15 ±1.91 pg/m L(range2.18-9.86), P =0.808, P =0.264].·CONCLUSION: Elevated melatonin levels in aqueous humor in PDR may indicate the level to be associated with DR severity. | Erdinc Aydin Semsettin Sahin | 2016 | International Journal of Ophthalmology(English edition)2016，9，5： | 4 |
| 6 | Effect of the ion nitriding surface hardening process on fa- tigue behavior of AISI 4340 steel 显示文摘 | Sule Y S Kahraman S Erdinc K | 2008 | Mater Charact2008，59，： | 1 |
| 7 | Profile changes of patients treated with and without premolar extractions 显示文摘 | Erdinc AE Nanda RS Dandajena TC | 2007 | Am J Orthod Dentofacial Orthop2007，132，3： | 1 |
| 8 | The risk factors for inections acquired by cerebral hemorrhage and cerebral in- farct patients in a neurology intensive care unit in Turkey显示文摘 | Yilmaz GR Cevik MA Erdinc FS | 2007 | Jpn J infect Dis2007，60，23： | 1 |
| 9 | Perception of pain during orthodontic treatment with fixed appliances显示文摘 | Erdinc AM Dincer B | 2004 | Eur J Orthod2004，26，1： | 1 |
| 10 | Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes显示文摘 | Raghu Kadaba Hanna Birke Jun Wang Steven Hooper Claudia D Andl Francesco Di Maggio Erdinc Soylu Mohammed Ghallab Daniel Bor Fieke EM Froeling Satyajit Bhattacharya Anil K Rustgi Erik Sahai Claude Chelala Peter Sasieni Hemant M Kocher | 2013 | J. Pathol2013，，1： | 1 |
| 11 | Moderate exercise with a dietaryvitamin C and e combination protects against streptozotocin-in-duced oxidative damage to the kidney and lens in pregnant rats显示文摘 | Simsek M Nazirogˇlu M Erdinc A | 2005 | Exp Clin Endocrinol Diabetes2005，113，1： | 1 |
| 12 | Efficiency of prostacyclin in the treatment of protamine - mediated fight ventficular failure and acute pulmonary hypentensio 显示文摘 | Ocal A Kiris I Erdinc M | 2005 | Tohoku J Exp Med2005，207，1： | 1 |
| 13 | A comparison of different treatment techniques for posterior cross - bite in mixed dentition显示文摘 | ERDINC A E UGUR T ERBAY E | 1999 | Am J Orthod Dentofacil Orthop1999，116，3： | 1 |
| 14 | Long-term results of balloon dacryocystoplasty: success rates according to the site and severity of the obstruction显示文摘 | Konuk O Ilgit E Erdinc A | 2008 | Eye (Lond)2008，22，： | 1 |
| 15 | Perception of pain during orthodontic treatment with fixed appliances显示文摘 | Erdinc AM Dincer B | 2004 | Eur J Orthod2004，26，1： | 1 |
| 16 | Oxidative stress and ferritin levels in haemodialysis patients显示文摘 | Senol E Ersoy A Erdinc S | 2008 | Nephrol Dial Transplant2008，23，2： | 1 |
| 17 | Surgical anatomy of the cervical sympathetic trunk during anterolateral approach to cervical spine显示文摘 | Erdinc Civelek Aykut Karasu Tufan Cansever | | 0，，： | 1 |
| 18 | Quadrature- error compensation and corresponding effects on the performance of fully deeoupled MEMS gyroscopes 显示文摘 | ERDINC T SAID E A TAYFUNA | 2012 | Journal of Micro-electromechanical Systems2012，21，3： | 1 |
| 19 | Optical coherence tomographic assessment of diabetic macular edema:com parison with fluorescein angiagraphic and clinical findings显示文摘 | Ozdek SC Erdinc MA Gurelik G | 2005 | Ophthalmolagica2005，219，2： | 1 |
| 20 | The risk factors for infections acquired by cerebral hemorrhage and cerebral infarct patients in a neurology intensive care unit in Turkey显示文摘 | Yilmaz GR Cevik MA Erdinc FS | 2007 | Jpn J Infect Dis2007，60，23： | 1 |
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