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| 1 | Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial显示文摘 | Martijn HGM van der Pas Eva Haglind Miguel A Cuesta Alois Fürst Antonio M Lacy Wim CJ Hop Hendrik Jaap Bonjer | 2013 | Lancet Oncology2013,,: | 17 |
| 2 | Autoimmune hepatitis and anti-tumor necrosis factor alpha therapy:A single center report of 8 cases显示文摘This article describes cases of anti-tumor necrosis factor(TNF)-α-induced autoimmune hepatitis and evaluates the outcome of these patients in relation to their immunosuppressive strategy. A retrospective analysis of medical records was performed in our center, in order to detect cases of autoimmune hepatitis(AIH) associated with anti-TNF biologic agents. We describe and analyze eight cases of AIH following anti-TNF therapy, 7 with infliximab and 1 with adalimumab. A distinction should be made between induction of autoimmunity and clinically evident autoimmune disease. Liver biopsy is useful in detecting the role of the TNF-α antagonist in the development of AIH. The lack of relapse after discontinuing immunosuppressive therapy favors, as in this case series, an immune-mediated drug reaction as most patients with AIH have a relapse after treatment is suspended. Although AIH related to anti-TNF therapy is rare, a baseline immunological panel along with liver function tests should be performed in all patients with autoimmune disease before starting biologics. | Susana Rodrigues Susana Lopes Fernando Magro Hélder Cardoso Ana Maria Horta e Vale Margarida Marques Eva Mariz Miguel Bernardes Joanne Lopes Fátima Carneiro Guilherme Macedo | 2015 | World Journal of Gastroenterology2015,21,24: | 9 |
| 3 | ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy显示文摘响应滋养的应力,房间开始能导致改编或死亡的一个 autophagy 节目。位于从饥饿发信号到 autophagy 的开始下面的机制充分没被理解。在当前的学习,我们证明 PARP-1 的缺席或 inactivation 强烈推迟导致饥饿的 autophagy。我们发现了那 DNA 损坏是由 γ 测量了的导致饥饿的 autophagy 的一个早事件; -H2AX 累积和彗星试金,与在两个参数显示减小的 PARP-1 猛烈房间。在饥饿期间,导致 ROS 的 DNA 损坏激活 PARP-1,导致 ATP 弄空(在滋养的剥夺以后的一个早事件) 。PARP-1 的缺席弄钝 AMPK 激活并且阻止了 mTOR 活动的完全的损失,导致在 autophagy 的延期。PARP-1 弄空在饥饿的房间赞成 apoptosis,建议在滋养的剥夺以后的 autophagy 和 PARP-1 激活的一个支持幸存的角色。在 PARP-1 变异的老鼠的出生不满一月的婴儿使遭到了到尖锐饥饿的 vivo 结果表演,也显示缺乏的肝 autophagy,暗示为在导致饥饿的 autophagy 的 PARP-1 的一个生理的角色。因此,表明小径的 PARP 是 autophagy 承诺追随者饥饿的起始的步骤的一个关键管理者。 | Jose Manuel Rodriguez-Vargas Maria Jose Ruiz-Magana Carmen Ruiz-Ruiz Jara Majuelos-Melguizo Andreina Peralta-Lea Maria Isabel Rodriguez Jose Antonio Munoz-Gaimez Mariano Ruiz de Almodovar Eva Siles Abelardo Lopez Rivas Marja Jaattela F Javier Oliver | 2012 | Cell Research2012,22,7: | 8 |
| 4 | Clinical use of dendritic cells for cancer therapy显示文摘 | Sébastien Anguille Evelien L Smits Eva Lion Viggo F van Tendeloo Zwi N Berneman | 2014 | Lancet Oncology2014,,7: | 3 |
| 5 | Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study显示文摘 | Pierre Fenaux Ghulam J Mufti Eva Hellstrom-Lindberg Valeria Santini Carlo Finelli Aristoteles Giagounidis Robert Schoch Norbert Gattermann Guillermo Sanz Alan List Steven D Gore John F Seymour John M Bennett John Byrd Jay Backstrom Linda Zimmerman David M | 2009 | Lancet Oncology2009,,: | 2 |
| 6 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021,18,9: | 2 |
| 7 | Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death显示文摘 | Alexander Seiler Manuela Schneider Heidi F?rster Stephan Roth Eva K. Wirth Carsten Culmsee Nikolaus Plesnila Elisabeth Kremmer Olof R?dmark Wolfgang Wurst Georg W. Bornkamm Ulrich Schweizer Marcus Conrad | 2008 | Cell Metabolism2008,,3: | 2 |
| 8 | The denaturation of circular enterocin AS-48 by urea and guanidinium hydrochloride显示文摘 | EVA S C VLADIMIR V F G/kLVEZ A | 2002 | Biochimica ET Biophysica Acta2002,1598,: | 1 |
| 9 | Determination of water-soluble hexavalent chromium in clinker samples bywavelength-dispersive x-ray fluorescence spectrometry after concentration in activated layers显示文摘 | Eva M Claudia F S Marta T | 2010 | Applied Spectroscopy2010,64,: | 1 |
| 10 | Understanding environmental influences on walking显示文摘 | Neville Owen Nancy Humpel Eva Leslie Adrian Bauman James F Sallis | 2004 | American Journal of Preventive Medicine2004,,1: | 1 |
| 11 | Composition of fatty acids and lipid classes in bulk products generated during enzymic hydrolysis of cod(Gadusmorhua)by-products显示文摘 | Egidijus D Eva F Rasa S | 2005 | Process Biochemistry2005,40,8: | 1 |
| 12 | FLUXNET:A New Tool to Study theTemporal and Spatial Variability of Ecosystem-scale Carbon Dio-xide,Water Vapor,and Energy Flux Densities显示文摘 | DENNIS B Eva F Gu L H | 2001 | Bulletin of the Amer-ican Meteorological Society2001,82,11: | 1 |
| 13 | Antifriction coatings of Pb-Sn-Cu alloy electro-deposited from methanesulphonate bath 显示文摘 | DANILOV F I PROTSENKO V S VASIL'EVA E A | 2011 | Transactions of the Institute of Metal Finishing2011,89,3: | 1 |
| 14 | Ligment reconstraction with or without tendon interposition to treat primary thumb carpometacarpal osteoarthritis 显示文摘 | Gabriele K Gert P Eva F | 2004 | J Bone Joint Surg(Am)2004,86,2: | 1 |
| 15 | Ceramic membrane ultrafihration of anionic and nonionic surfactant solutions 显示文摘 | Eva F Benito J M Pazos C | 2005 | Journal of Membrane Science2005,246,1: | 1 |
| 16 | The role of active oxygen species in plant signal transduction 显示文摘 | FRANK V EVA V JAMES F D | 2001 | Plant Science2001,161,3: | 1 |
| 17 | Laparoscopic versus open surgery for rectal cancer (COLOR II): short-term outcomes of a randomised, phase 3 trial显示文摘 | Martijn HGM van der Pas Eva Haglind Miguel A Cuesta Alois Fürst Antonio M Lacy Wim CJ Hop Hendrik Jaap Bonjer | 2013 | Lancet Oncology2013,,: | 1 |
| 18 | Resistant starch and the'bntyrate revolution'显示文摘 | Brouns F Kettlitz B Arrigoni Eva | 2002 | Trends in Food Science & Technology2002,13,: | 1 |
| 19 | Content of polyunsaturated fatty-acids and cholesterol in musde tissue of tench (Tinca tinca),common carp(Cyprinus carpio)and hybrid of bighead carp (Aristichthys nobilis)with silver carp (Hypophthalmichthys molitrix )显示文摘 | Vacha F Eva T | 1995 | Polskie archiwum hydrobiology1995,42,12: | 1 |
| 20 | Energy balance closure at FLUXNET sites显示文摘 | KELL W ALLEN G EVA F | 2002 | Agricultural and Forest Meteorology2002,113,: | 1 |