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	题名	作者	年代	出处	被引量
1	胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。	Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉叶鹏	2017	中华高血压杂志2017，25，9：	2
2	Autophagosome-associated variant isoforms of cytosolic enzymes显示文摘	Fengsrud M Raiborg C Berg TO Strmhaug PE Ueno T Erichsen ES Seglen PO	2000	Biochem J2000，352，3：	1
3	Alteration of immunological properties of bovine serum albumin by covalent attachment of polyethylene glycol显示文摘	ABUCHOWSKI A VAN ES T PALCZUK N C	1977	J Biol Chem1977，252，11：	1
4	CPP32,a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interlerkin-1 betas-converting enzyme显示文摘	FERNANDES-ALNERMRI T LITWACK G ALNERMRI ES	1994	J Biol Chem1994，269，30：	1
5	Incidence,prevention and treatment of pressure ulcers in intensive care patients :a longitude study显示文摘	Shashin ES Dassen T Halfens ILl	2008	J Eva[ CIin Praet2008，14，4：	1
6	CPP32 a novel human apoptotic protein with homology to Cae- norhabditis elegans cell death protein Ced-3 and mammalian in- terleukin-1 betaeonverting enzyme显示文摘	FERNANDES-ALNEMRI T LITWACK G ALNEMRI ES	1994	J Biol Chem1994，269，30：	1
7	Profile of microbial communities present in tibico(sugary kefir)grains from different Brazilian States显示文摘	da CP MIGUEL M G CARDOSO P G MAGALHES K T	2011	World Journal of Microbiology and Biotechnology2011，27，8：	1
8	Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18显示文摘	Wataganara T LeShane ES Farina A	2003	Hum Genet2003，112，2：	1
9	Maternal serum cell-free fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18显示文摘	Wataganara T LeShane ES Farina A	2003	Hum Genet2003，112，2：	1
10	Gefitinib versus doeetaxel in previously treated non-smalbeell lung cancer(INTEREST): arandomised phase Ⅲ trial 显示文摘	Kim ES Hirsh V Mok T	2008	Lancet2008，372，9652：	1
11	Workshop report on Hodgkin ' s disease and related diseases (grey zone' lymphoma) 显示文摘	Rtldiger T Jaffe ES Delsol G	1998	Ann On- col1998，95，：	1
12	Molecular characterization of NF-HEV, a nuclear factor preferentially expressed in human high endothelial venules 显示文摘	Baekkevold ES Rottigne M Yamanaka T	2003	Am J Pathol2003，163，1：	1
13	Firing distance estimation through the analysis of the gunshot residue deposit pattern around the bullet entrance hole by inductively coupled plasma-mass spectrometry:an experimental study显示文摘	Santos A Magalh?es T Vieira DN		0，，01：	1
14	Active learning paradigms for CBIR systems based on optimum-path forest classification 显示文摘	da SILVA A T FALC?O A X MAGALH?ES L P	2011	Pattern Recognition2011，44，12：	1
15	Maternal serum cellfree fetal DNA levels are increased in cases of trisomy 13 but not trisomy 18 显示文摘	Wataganara T LeShane ES Farina A	2003	Hum Genet2003，112，2：	1
16	Cholesterol and the risk of renal dysfunction in apparently healthy men显示文摘	Schaeffner ES Kurth T Curhan GC	2003	J Am Soc Nephrol2003，14，8：	1
17	Bibliotherapy and Perceptions of Death by Young Children显示文摘	Jeffrey T Thomas ES Michael B	1998	Journal of Poetry Therapy1998，12，2：	1
18	Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection显示文摘	Daar ES Moudgil T Meyer RD	1991	N Engl J Med1991，324，14：	1
19	Research ethics in animal models显示文摘	Miziara I D Magalha es A T Santos M d	2012	Braz J Otorhinolaryngol2012，78，2：	1
20	Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST):a randomized phase Ⅲ trial显示文摘	Kim ES Hirsh V Mok T		0，，9652：	1

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