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| 1 | Gallbladder polyps: Factors affecting surgical decision显示文摘AIM: To determine the factors affecting the decision to perform surgery, and the efficiency of ultrasonography (USG) in detecting gallbladder polyps (GP). METHODS: Data for 138 patients who underwent cholecystectomy between 1996 and 2012 in our clinic with a diagnosis of GP were retrospectively analyzed. Demographic data, clinical presentation, principal symptoms, ultrasonographic and histopathological findings were evaluated. Patients were evaluated in individual groups according to the age of the patients (older or younger than 50 years old) and polyp size (bigger or smaller than 10 mm) and characteristics of the polyps (pseudopolyp or real polyps). χ 2 tests were used for the statistical evaluation of the data. RESULTS: The median age was 50 (26-85) years and 91 of patients were female. Of 138 patients who underwent cholecystectomy with GP diagnosis, only 99 had a histopathologically defined polyp; 77 of them had pseudopolyps and 22 had true polyps. Twenty-one patients had adenocarcinoma. Of these 21 patients, 11 were male, their median age was 61 (40-85) years and all malignant polyps had diameters > 10 mm (P< 0.0001). Of 138 patients in whom surgery were performed, 112 had ultrasonographic polyps with diameters < 10 mm. Of the other 26 patients who also had polyps with diameters > 10 mm, 22 had true polyps. The sensitivity of USG was 84.6% for polyps with diameters > 10 mm (P < 0.0001); however it was only 66% in polyps with diameters < 10 mm. CONCLUSION: The risk of malignancy was high in the patients over 50 years old who had single polyps with diameters > 10 mm. | Pinar Sarkut Sadik Kilicturgay Ali Ozer Ersin Ozturk Tuncay Yilmazlar | 2013 | World Journal of Gastroenterology2013，19，28： | 12 |
| 2 | REKF and RUKF for pico satellite attitude estimation in the presence of measurement faults显示文摘When a pico satellite is under normal operational conditions, whether it is extended or unscented, a conventional Kalman filter gives sufficiently good estimation results. However, if the measurements are not reliable because of any kind of malfunctions in the estimation system, the Kalman filter gives inaccurate results and diverges by time. This study compares two different robust Kalman filtering algorithms, robust extended Kalman filter(REKF) and robust unscented Kalman filter(RUKF), for the case of measurement malfunctions. In both filters, by the use of defined variables named as the measurement noise scale factor, the faulty measurements are taken into the consideration with a small weight, and the estimations are corrected without affecting the characteristic of the accurate ones. The proposed robust Kalman filters are applied for the attitude estimation process of a pico satellite, and the results are compared. | Halil Ersin Sken Chingiz Hajiyev | 2014 | Journal of Systems Engineering and Electronics2014，25，2： | 9 |
| 3 | Effects of glutamine and curcumin on bacterial translocation in jaundiced rats显示文摘AIM: To investigate the effect of curcumin on bacterial translocation and oxidative damage in an obstructive jaundice model and compare the results to glutamine, an agent known to be effective and clinically used. METHODS: Twenty-four female Wistar-Albino rats, weighing 200-250 g, were randomly divided into three groups (8 in each group). After ligation of the common bile duct in all animals, GroupⅠ received oral normal saline, Group Ⅱ received oral glutamine and Group Ⅲ received oral curcumin for seven days. Blood samples via cardiac puncture, tissue samples (terminal ileum, liver and mesenteric lymph node) and peritoneal fluid were obtained from the animals at the time of death to investigate bacterial translocation and oxidative damage. RESULTS: We observed that both glutamine and curcumin reduced bacterial translocation in blood, hepatocellular damage, plasma cytokine levels, oxidative tissue damage and apoptosis significantly compared to the control group. Additionally, glutamine showed protective effects on ileal epithelium and reduced villus atrophy. CONCLUSION: On the basis of these findings, both curcumin and glutamine are thought to be effective in preventing or reducing bacterial translocation and oxidative damage in obstructive jaundice. | Oguzhan Karatepe Ersin Acet Muharrem Battal Gokhan Adas Ahu Kemik Merih Altiok Gulcin Kamali Safiye Koculu Atahan Catay Sedat Kamali Servet Karahan | 2010 | World Journal of Gastroenterology2010，16，34： | 5 |
| 4 | Cementomimetics——constructing a cementum-like biomineralized microlayer via amelogenin-derived peptides显示文摘Cementum is the outer-,mineralized-tissue covering the tooth root and an essential part of the system of periodontal tissue that anchors the tooth to the bone. Periodontal disease results from the destructive behavior of the host elicited by an infectious biofilm adhering to the tooth root and left untreated,may lead to tooth loss. We describe a novel protocol for identifying peptide sequences from native proteins with the potential to repair damaged dental tissues by controlling hydroxyapatite biomineralization. Using amelogenin as a case study and a bioinformatics scoring matrix,we identified regions within amelogenin that are shared with a set of hydroxyapatite-binding peptides (HABPs) previously selected by phage display. One 22-amino acid long peptide regions referred to as amelogenin-derived peptide 5 (ADP5) was shown to facilitate cell-free formation of a cementum-like hydroxyapatite mineral layer on demineralized human root dentin that,in turn,supported attachment of periodontal ligament cells in vitro. Our findings have several implications in peptide-assisted mineral formation that mimic biomineralization. By further elaborating the mechanism for protein control over the biomineral formed,we afford new insights into the evolution of protein-mineral interactions. By exploiting small peptide domains of native proteins,our understanding of structure-function relationships of biomineralizing proteins can be extended and these peptides can be utilized to engineer mineral formation. Finally,the cementomimetic layer formed by ADP5 has the potential clinical application to repair diseased root surfaces so as to promote the regeneration of periodontal tissues and thereby reduce the morbidity associated with tooth loss. | Mustafa Gungormus Ersin E Oren Jeremy A Horst Hanson Fong Marketa Hnilova Martha J Somerman Malcolm L Snead Ram Samudrala Candan Tamerler Mehmet Sarikaya | 2012 | International Journal of Oral Science2012，4，2： | 5 |
| 5 | 牙本质粘结剂和氢氧化钙在人牙和羊牙直接盖髓的比较研究显示文摘目的比较一步法牙本质粘结剂(Prime&Bond2.1)和氢氧化钙在直接盖髓方面的生物相容性。材料和方法选择30颗羊牙和20颗完整的人前磨牙。备洞,车针(390#)造成穿髓。25颗牙齿(15颗羊牙和10颗人牙)粘结剂盖髓,对照组(12颗羊牙和10颗人牙)氢氧化钙盖髓。所有窝洞用复合树脂充填。3颗羊牙作为空白对照。治疗后的第7天和第90天拔除牙齿,进行组织学分析和细菌学检测。结果第7天时,以粘接剂盖髓的人牙和羊牙中,粘接剂下方出现了严重的炎性反应,并可观察到冠髓的软组织结构遭到破坏。以氢氧化钙盖髓的所有牙齿则表现为仅限于穿髓区域的轻度炎性反应。第90天时,粘接剂组9颗羊牙中的3颗表现出慢性炎症反应,其余6颗为轻度牙髓反应,且9颗羊牙均有牙本质桥形成;而粘接剂盖髓人牙组中,观察到的是缺乏牙本质桥形成和持续而不缓解的炎症。对照组氢氧化钙盖髓的所有牙,包括羊牙和人牙,都有牙本质桥形成的牙髓修复反应。采用Spearman等级相关分析表明炎症的出现和细菌染色没有相关性(P〉0.05)。结论Prime&Bond2.1粘接体系用于羊牙盖髓时,能促进牙髓愈合和牙本质桥形成,但当其作为盖髓剂用于人牙时,尚不能获得像氢氧化钙那样的盖髓效果。 | Nazan Kocatas Ersin Nesrin Eronat 范蓉(译) 张成飞(校) | 2007 | 中国口腔医学继续教育杂志2007，10，1： | 2 |
| 6 | Does pelvic injury trigger erectile dysfunction in men?显示文摘 | H. Huseyin Ceylan Ersin Kuyucu Remzi Erdem Gokhan Polat Ferit Yllmaz Bilal Gumus Mehmet Erdil | 2015 | Chinese Journal of Traumatology2015，18，4： | 2 |
| 7 | Anti-inflammatory efficiency of levobupivacaine in an experimental colitis model显示文摘AIM:To investigate the efficiency of levobupivacaine in treating experimentally induced colitis in rats.METHODS:Colitis was induced by trinitrobenzene sulfonic acid and ethanol in 30 rats under general anesthesia,and 10 rats were used as a sham group.Subsequent to induction of colitis,rats were divided into three groups;budesonide group received 0.1 mg/kg budesonide,levobupivacaine group received 10 mg/kg levobupivacaine and saline group received 1 mL saline solution via rectal route for 7 d.In the sham group,only routine rectal catheterization was performed without use of any material.At the end of 7 d,laparotomy and total colectomy were performed for histopathological ex-amination in all rats and blood samples were drawn for measurement of tumor necrosis factor(TNF)-αand interleukin(IL)-6 following cardiac puncture.Macroscopic and microscopic evaluations of the specimens were performed by a pathologist blinded to group assignment of the rats.RESULTS:Weight loss(P=0.016)and macroscopic examination scores(P=0.001)were significantly higher in saline group than others.Histopathological scoring was comparable between all colitis groups(P=0.350).There was no significant difference in TNF-αlevels and IL-6 levels(P=0.150).CONCLUSION:The significant improvement in macroscopic scores suggests that levobupivacaine may have topical anti-inflammatory effects in an experimental colitis model;however,this finding was not supported by microscopic findings. | Ugur Duman Aysun Yilmazlar Ersin Ozturk Sibel Aker Emre Sarandol Tuncay Yilmazlar | 2010 | World Journal of Gastroenterology2010，16，20： | 2 |
| 8 | Primary hepatic carcinosarcoma显示文摘BACKGROUND:Primary hepatic carcinosarcoma is a rare malignant tumor containing an intimate mixture of carci- nomatous and sarcomatous elements.Reports on risk factors, epidemiology,and pathogenesis of the tumor as well as the experience in its treatment are limited. METHOD:We present a case of primary carcinosarcoma of the liver in a 69-year-old man who complained of right hypochondrial pain and weight loss for two months. RESULTS:Magnetic resonance imaging revealed a 14×12 cm mass in segments 7-8 and 4 of the liver with vena hepatica invasion.An ultrasonography-guided biopsy showed osteoid tissue without osteoblastic rimming.Vascular structures accompanied the osteoid tissue.The patient underwent surgery after a diagnosis of hemangioma.Intraoperative frozen sections revealed a carcinosarcoma associated with an osteosarcoma and cholangiocellular carcinoma components. CONCLUSIONS:Preoperative diagnosis of this rare primary hepatic malignant tumor may be difficult by biopsy owing to intratumoral heterogeneity.Highly mature areas of the osteosarcomatous component may lead to misdiagnosis of metaplastic bone tissue.Clinicopathologic features of this rare entity are discussed. | Mehmet elikbilek Kemal Deniz Edip Torun Tarιk Artιs Ersin zaslan kkes brahim Karahan Tahir Ercan Patιroglu mer zbakιr | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，1： | 2 |
| 9 | Oral and dental manifestations of gastroesophageal reflux disease in children: a preliminary study 显示文摘 | Ersin NK Oncaq O Tumqor G | 2006 | Pediatr Dent2006，28，3： | 1 |
| 10 | Adhesion and fatigue properties of Ti/TiB2/MoS2 graded-composite coatings deposited by closed-field unbalanced magnetron sputtering显示文摘 | Faruk Bidev (o)zlem Baran Ersin Arslan | | 0，，： | 1 |
| 11 | Diversity Analysis of Single and Multiple Beamforming显示文摘 | Ersin Sengul Enis Akay Ender Ayanoglu | 2006 | IEEE Transactions on communications2006，54，06： | 1 |
| 12 | Comparison of the classic limberg flap and modified limberg flap in the treatment of pilonidal sinus disease: A retrospective analysis of 416 patients显示文摘 | Murat Akin Sezai Leventoglu B. Bulent Mentes Hasan Bostanci Hakan Gokbayir Kadir Kilic Ersin Ozdemir Zafer Ferahkose | 2010 | Surgery Today2010，，8： | 1 |
| 13 | Forecasting volatility in oil prices with a class of nonlinear volatility models:smooth transition RBF and MLP neural networks augmented GARCH approach显示文摘In this study, the forecasting capabilities of a new class of nonlinear econometric models, namely, the LSTAR-LST-GARCH-RBF and MLP models are evaluated. The models are utilized to model and to forecast the daily returns of crude oil prices. Many financial time series are subjected to leptokurtic distribution, heavy tails, and nonlinear conditional volatility. This characteristic feature leads to deterioration in the forecast capabilities of traditional models such as the ARCH and GARCH models.According to the empirical findings, the oil prices and their daily returns could be classified as possessing nonlinearity in the conditional mean and conditional variance processes.Several model groups are evaluated:(i) the models proposed in the first group are the LSTAR-LST-GARCH models that are augmented with fractional integration and asymmetric power terms(FIGARCH, APGARCH, and FIAPGARCH);(ii) the models proposed in the second group are the LSTAR-LST-GARCH models further augmented with MLP and RBF type neural networks. The models are compared in terms of MSE, RMSE, and MAE criteria for in-sample and out-of-sample forecast capabilities. The results show that the LSTAR based and neural network augmented models provide important gains over the single-regime baseline GARCH models, followed by the LSTAR-LST-GARCH type models in terms of modeling and forecasting volatility in crude oil prices. | Melike Bildirici zgÖrü Ersin | 2015 | Petroleum Science2015，12，3： | 1 |
| 14 | Effects of nitric oxide synthase inhibition on spatial discrimination learning and central DA2 and mACh receptors显示文摘 | Ersin O. Koylu Lutfiye Kanit Dilek Taskiran Taner Dagci Burcu Balkan Sakire Pogun | 2005 | Pharmacology, Biochemistry and Behavior2005，，1： | 1 |
| 15 | Effects of somatostin analogues and vitamin C on bacterial translocation in an experimental intestinal obstr- cution model of rats显示文摘 | Ersin S Oymaci E | 2000 | J Invest Surg2000，13，： | 1 |
| 16 | Effects of somatostatin analogues and vitamin C on bacterial translocation in an experimental intestinal obstruction model of rats显示文摘 | Akyildiz M Ersin S Oymaci E | 2000 | Invest Surg2000，13，3： | 1 |
| 17 | Synthesis of clay-based superabsorbent composite and its sorption capability显示文摘 | Yasemin Bulut Gülten Ak?ay Duygu Elma I. Ersin Serhatl? | 2009 | Journal of Hazardous Materials2009，，1： | 1 |
| 18 | Geochemistry and Zircon U-Pb Dates of Felsic-Intermediate Members of the Late Cretaceous Yüksekova Arc Basin: Constraints on the Evolution of the Bitlis–Zagros Branch of Neotethys(Elazig, E Turkey)显示文摘During the Late Cretaceous in the Eastern Mediterranean, the northern branch of the southern Neotethys was closed by multiple northward subductions. Of these, the most northerly located subduction created the Baskil continental arc at around 82–84 Ma. The more southerly and intra-oceanic subduction, on the other hand, produced an arc-basin system,the Yüksekova Complex, as early as the late Cenomanian–early Turonian. The abundant and relatively well-studied basaltic rocks of this complex were intruded by dykes, sills and small stocks of felsic–intermediate rocks, not previously studied in detail. The intrusives collected from five different localities in the Elazig region of eastern Turkey are all subalkaline, with low Nb/Y values. Most of them have been chemically classified as rhyodacites/dacites, whereas a small number appear to be andesites. In normal mid-ocean-ridge basalt(N-MORB)-normalised plots, the intrusives are characterised by relative enrichments in Th and La over Nb, Zr, Hf, Ti and high field strength elements(HREEs), indicating their derivation from a subduction-modified source. While their relatively high, positive εN d(i) values(+6.4 and +7.2) might suggest a depleted mantle source for their ultimate origin, somewhat radiogenic Pb values indicate a sedimentary contribution to the source of the rocks. The overall geochemical characteristics indicate their generation in an oceanic arc setting. The zircon U-Pb Laser ablation-inductively coupled plasma-mass spectrometry(LA-ICP-MS) data obtained from five felsic-intermediate rock samples yielded intrusion dates of 80–88 Ma. This suggests that the Elazig oceanic arc-related intrusives are slightly younger than those of the Yüksekova arc-basin system, but coeval with the Baskil continental arc. However, the felsic–intermediate intrusives show different geochemical characteristics(oceanic arc-type, with a lack of crustal contamination)to those of the Baskil continental arc. This indicates that these two igneous systems are unrelated and likely developed in different tectonic settings. This, in turn, supports a geodynamic model in which the northern strand of the southern Neotethys was consumed by multiple northward subductions. | Melek URAL Kaan SAYIT Osman Ersin KORALAY Mehmet Cemal GONCUOGLU | 2021 | Acta Geologica Sinica(English Edition)2021，95，4： | 1 |
| 19 | Co -localization of cart peptide immunoreactivity and nitric oxide synthase activity in rat hypothalamus显示文摘 | Ersin OK Eduardo W Burcu B | 2000 | Brain Res2000，868，： | 1 |
| 20 | Oral and dental monifestations of gastroesophageal reflux disease in children:a preliminary study 显示文摘 | Ersin NK Oncag D Tumgor G | 2006 | Pediatr Dent2006，28，3： | 1 |
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