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1Protective effect of ascorbic acid on cyclophosphamide induced testicular gametogenic and androgenic disorders in male rats显示文摘Aim:To study the detrimental effects of cyclophosphamide on the testicular androgenic and gametogenic activities through endocrine inhibiton and/or induction of oxidative stress in male albino rats and to evaluate the protective effect of ascorbic acid.Methods:The testicular△^5,3β-hydroxysteroid dehydrogenase(HSD),17β-HSD,peroxidase and catalase activities along with the levels of malondialdehyde(MDA)and conjugated dienes in testicular tissue were measured for the evaluation of testicular oxidative stress.The plasma testosterone(T)level was measured by immunoassay7.Various germ cells at stage VⅡof spermatogenic cycle were quantified from testicular stained sections.Results:Cyclophosphamide treatment results in a significant inhibition in the testicular△^5,3β-HSDand17β-HSDactivities,a decrease in plasma T level and a diminution in the coumts of various gern cells,Moreover,this treatment was also associated with a significant inhibition of the peroxidase and catalase activities along with high levels of MDA and conjugated dienes in the testis.All these changes were reversed by ascorbic acid co-administration.Conclusion:Cyclophosphamide treatment at the dosage used caused testicular gametogenic and androgenic disor-ders as well as induced testicular oxidative stress that can be reversed by ascorbic acid co-administration.Ujjal Baran Das Mousumi Mallick Jogendra Mohan Debnath Debidas Ghosh 2002Asian Journal of Andrology2002,4,3:27
2Oxidative stress and nitric oxide in rats with alcohol-induced acute pancreatitis显示文摘AIM: Oxygen free radical mediated tissue damage is well established in pathogenesis of acute pancreatitis (AP).Whether nitric oxide (NO) plays a deleterious or a protective role is unknown. In alcohol-induced AP, we studied NO, lipooxidative damage and glutathione in pancreas, lung and circulation.METHODS: AP was induced in rats (n = 25) by injection of ethyl alcohol into the common biliary duct. A sham laparatomy was performed in controls (n = 15). After 24 h the animals were killed, blood and tissue sampling were done.RESULTS: Histopathologic evidence confirmed the development of AP. Marked changes were observed in the pulmonary tissue. Compared with controls, the AP group displayed higher values for NO metabolites in pancreas and lungs, and thiobarbituric acid reactive substances in circulation. Glutathione was lower in pancreas and in circulation. Glutathione and NO were positively correlated in pancreas and lungs of controls but negatively correlated in circulation of experimental group. In the experimental group, plasma thiobarbituric acid reactive substances were negatively correlated with pancreas thiobarbituric acid reactive substances but positively correlated with pancreas NO.CONCLUSION: NO increases in both pancreas and lungs in AP and NO contributes to the pathogenesis of AP under oxidative stress.Gülnur Andican Remisa Gelisgen Ethem Unal Osman Baran Tortum Sergülen Dervisoglu Tayfun Karahasanoglu Gülden Bur(?)ak 2005World Journal of Gastroenterology2005,11,15:18
3Long-term vision-threatening complications of phakic intraocular lens implantation for high myopia显示文摘AIM:To report the long-term vision-threatening complications in patients who underwent phakic intraocular lens(pIOLs)implantation for high myopia.METHODS:Thisstudywasdesignedfromaconsecutive series of phakic intraocular lens complication and corrective surgeries.Sixteen eyes of 13 patients had implantation of phakic intraocular lens for correction high myopia and developed serious complications have been included in this study.The mean age of patients was 38.6±6.35y(range 32-50y)and the mean time of history of pIOL implantation for high myopia was 6±2y(range 2-10y).Before corrective surgery,best spectaclecorrective visual acuity(BSCVA)ranged from perception to 20/200 in the eyes in which severe complications occurred.RESULTS:Corneal decompensation occurred in 12eyes of 9 high myopic patients after anterior chamber pIOL implantation.Rhegmatogenous retinal detachment(RRD)occurred in 4 eyes of 4 high myopic patients following anterior chamber and posterior chamber pIOL implantation.Patients with corneal decompensation,had combined procedures consisting of pIOL removal and penetrating keratoplasty(PKP).Removals of pIOL,phacoemulsification and pars plana vitrectomy(PPV)with silicone oil tamponade were performed in patients with RRD.After corrective surgeries,all patients but one(P+,patient 2,right eye)achieved moderate BSCVA ranged from 20/200 to 20/50 at the last visit.CONCLUSION:Phakic IOLs may be effective for thecorrection of high myopia.Although these IOLs may have severe complications and it affects safety and efficacy of this surgery.As seen here,corneal decompensation and rhegmatogenous retinal detachment are possible postoperative vision-threatening complications of phakic IOLs.Patients must be carefully examined before and after surgery for possible endothelial cell loss and vitreoretinal problems.Isil Bahar Sayman Muslubas Baran Kandemir Ayse Yesim Aydin Oral Suleyman Kugu Metin Dastan 2014International Journal of Ophthalmology(English edition)2014,7,2:14
4计及分布式电源无功特性的弱环配电网复仿射潮流算法显示文摘为解决前推回代复仿射潮流算法在弱环及多分布式电源(DG)接口类型配电网中的适用性问题,在详细分析前推回代复仿射潮流计算特点的基础上,引入基于道路矩阵的回路分析法来解决该适应性问题。随后,针对仿射算术无法在区间不确定性条件下准确描述DG无功控制特性的不足,采用无功灵敏度矩阵与电压灵敏度矩阵两步修正的方式,提出了可计及DG无功控制特性的复仿射潮流改进算法。最后,基于IEEE 33节点系统、PG&E 69节点系统以及实际113节点系统扩展的含多DG接口类型的不同规模配电网验证了所提算法的有效性与准确性。陈鹏伟 肖湘宁 Mesut BARAN 2019电力系统自动化2019,43,7:13
5Non-alcoholic fatty liver disease: What has changed in the treatment since the beginning?显示文摘Non-alcoholic fatty liver disease(NAFLD) is an umbrella term to describe the entire spectrum of this common liver disease. In patients with NAFLD, especially those with non-alcoholic steatohepatitis(NASH), most often have one or more components of the metabolic syndrome, but this is not universal. Although most patients with NAFLD share many clinical features, only a subset of patients develops significant liver inflammation and progressive fibrosis. On the other hand, not all patients with NASH exhibit insulin resistance. NASH can be seen in patients who are lean and have no identifiable risk factors. Many clinical studies have tried numerous drugs and alternative medicine, however, investigators have failed to identify a safe and effective therapy for patients with NASH. As summarized, the heterogeneity of pathogenic pathways in individual patients with NASH may warrant the development of an individualized treatment according to the underlying pathogenic pathway. The differentiation of pathogenetic targets may require the development of diagnostic and prognostic biomarkers, and the identification of genetic susceptibilities. At present, evidence-based medicine provides only a few options including life-style modifications targeting weight loss, pioglitazone and vitamin E in non-diabetic patients with biopsy-proven NASH.Bülent Baran Filiz Akyüz 2014World Journal of Gastroenterology2014,20,39:10
6Nucleos(t)ide analogs in the prevention of hepatitis B virus related hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is among the most common cancer types and causes of cancer related mortality worldwide.Almost 50% of all HCC cases globally are attributable to chronic hepatitis B virus(HBV) infection.The incidence rates of HCC in untreated Asian subjects with HBV infection was estimated to be 0.2% in inactive carriers,0.6% for those with chronic hepatitis without cirrhosis,and 3.7% for those with compensated cirrhosis.In Western populations,HCC incidences are reported to be 0.02% in inactive carriers,0.3% in subjects with chronic hepatitis without cirrhosis,and 2.2% in subjects with compensated cirrhosis.Despite effective antiviral treatment options which are able to transform chronic hepatitis into an inactive carrier state,the risk of HCC cannot be fully ruled out to exclude those patients from surveillance.Newer nucleos(t)ide analogues(NAs) as entecavir and tenofovir are very potent in terms of sustained virological suppression which leads to improved liver histology.However,they do not have any influence on the ccc DNA or integrated DNA of HBV in the liver.Nonetheless,viral replication is the only modifiable component among the established risk factors for HBV-related HCC with the current treatment options.In this review,it was aimed to summarize cumulative evidence behind the concept of prevention of HBV related HCC by NAs,and to discuss remaining obstacles to eliminate the risk of HCC.Bulent Baran 2015World Journal of Hepatology2015,7,13:8
7Comparison of visual and topographic outcomes of deep-anterior lamellar keratoplasty and penetrating keratoplasty in keratoconus显示文摘AIM:To compare visual,surgical and topographic outcomes of deep anterior lamellar keratoplasty(DALK)and penetrating keratoplasty(PK)for keratoconus(KC).METHODS:In this multicenter,prospective,randomized clinical trial 76 eyes of 71 KC patients operated between January 2011 and July 2014 in 2 tertiary referral hospitals were included. Consecutive patients were alternately selected to receive one of the two surgical methods. Thirty eight eyes underwent DALK with the big-bubble technique and 38 eyes underwent PK.RESULTS:Mean best spectacle corrected visual acuity(BSCVA)at the first postoperative week(P=0.012)and the first postoperative month(P<0.001)was statistically significantly higher in DALK group. The mean BSCVA at12 mo was not significantly different for DALK(0.30±1.99 log MAR)versus PK(0.40±0.33 log MAR)(P=0.104). The76.3% of the eyes had a BSCVA over 0.5 in DALK and 47.4%in PK group(P=0.009). The 7.9% of the eyes had a BSCVA of 1.0 in DALK and 5.3% in PK group(P=0.644). Mean spherical equivalent was-2.94 D in DALK and-3.09 D in PK group.Mean topographic astigmatism was 4.62 D and 4.18 D respectively. Regular topographic patterns were observed in 31(81.6%)of DALK and 29(76.3%)of PK(P=0.574). The most frequent topographic pattern was oblate asymmetric bow tie,seen in 39.5% in DALK and 23.7% in PK. CONCLUSION:Big bubble DALK provides an earlier visual improvement compare to PK. However,visual and topographic outcomes are similar to those in PK at 1y. Postoperative complications including rejection and intraocular pressure elevation are more frequent in PK. DALK is a safer alternative to PK for KC. However,intraoperativeperforation of the Descemet's membrane is a significant complication.Bora Yüksel Baran Kandemir Umut Duygu Uzunel Ozan Celik Sezgin Ceylan Tuncay Küsbeci 2017International Journal of Ophthalmology(English edition)2017,10,3:5
8以天然沥青岩为原料制备高压缩强度的泡沫炭(英文)显示文摘以安纳托利亚东南部的天然沥青岩为原料制备泡沫炭。所制泡沫炭的平均孔径和密度分别为150μm和800 kg/m3。主要研究了压力、温度、泄压时间及在最高温度时的停留时间对泡沫形成的影响,同时还评价了炭化过程对泡沫结构的影响。主要研究了压力、温度、泄压时间及在最高温度时的停留时间对泡沫炭进行了表征,并进行了密度及抗压强度分析。结果表明,1 323 K炭化后,泡沫炭压缩强度由10 MPa增加到18.7 MPa。沥青的灰分含量(41.76%)对泡沫炭的密度和压缩强度起重要作用。Deniz Baran Mehmet Ferhat Yardim Hüsnü Atakül Ekrem Ekinci 2013新型炭材料2013,28,2:4
9Comparison of contrast sensitivity and visual acuity between deep anterior lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus显示文摘AIM: To evaluate postoperative visual acuity and contrast sensitivity results following deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) in patients with keratoconus (KC). METHODS: All the patients' records with KC who had PK or DALK surgery between May 2010 and May 2011 were retrospectively reviewed. Sixty patients who underwent successful corneal transplantation for KC: 30 eyes underwent DALK and 30 eyes underwent PK were included in this study. Preoperative and postoperative mean logarithm of the minimum angle of resolution (logMAR) uncorrected visual acuity (UCVA), logMAR best spectacle-corrected visual acuity (BSCVA) and intraocular pressure (IOP) were evaluated. Contrast sensitivity tests (CS) were done preoperative and 2 months after all sutures had removed. All surgeries were performed under regional anesthesia (retrobulbar anesthesia) by 1 surgeon (B.K.) who was experienced in penetrating and lamellar keratoplasty techniques. RESULTS: The mean age of the DALK group was 29.67±4.95 (range 18-40) years and the PK group was 28.7±3.53 (range 18-39) years. Preoperatively there was no significant difference in the logMAR UCVA, logMAR BSCVA and IOP between the DALK (1.281±0.56; 0.97±0.85; 12.07±2.12mmHg) and PK (1.34±0.21; 0.98±0.21; 13±2.12mmHg) groups. One-year after surgery there was no significant difference in the mean logMAR UCVA and IOP between the DALK (0.46±0.37; 11.73±2.1mmHg) and PK (0.38±0.21; 12±2.12mmHg) groups. The mean contrast sensitivity was evaluated by CC-100 Topcon LCD at 1.5, 2.52, 4.23, 7.10 and 11.91 cycles per degree (cs/deg) spatial frequencies before and 2 months after the all sutures had removed. CONCLUSION: All patients with keratoconus in both DALK and PK groups performed good visual function postoperatively. The mean contrast sensitivity increased considerably at all spatial frequencies compared with preoperative levels in the DALK and PK groups. The mean post-operative evaluation of contrast sensitivity measurements was not significantly different between the two groups.Mehmet Orcun Akdemir Baran Kandemir Isil Bahar Sayman Cem Selvi OmerKamil Dogan 2012International Journal of Ophthalmology(English edition)2012,5,6:3
10Evaluation of cardiovascular risk in patients with Parkinson disease under levodopa treatment显示文摘BackgroundLevodopa 是在有 Parkinson 疾病(PD ) 的病人的中间的治疗的不可缺少的选择。因为 L-dopa 治疗被显示增加浆液 homocysteine 层次,为心血管的混乱的一个著名风险因素,有在 L-dopa 治疗下面的 PD 的病人将在为未来的增加的风险心血管的事件。这研究的目的是在 levodopa treatment.MethodsThe 学习下面与 PD 在病人评估心血管的风险人口在 L-dopa 治疗下面与自发的 PD 由 65 个病人组成了。控制组包括了 32 年龄,性匹配没有认知衰落的个人。Echocardiographic 大小,浆液 homocysteine 层次和主动脉的有弹性的参数与 PD 和 controls.ResultsAs 在病人之间被作比较 L-dopa 治疗的一个期望的特征, Parkinson 组有显著地更高的 homocystein 层次(15.1 ±3.9 µ mol/L 对 11.5 ±3.2 µ mol/L, P = 0.02 ) 。当时,大动脉的膨胀性在有 PD 的病人是显著地更低的与控制相比(4.8 ±1.5 dyn/cm 2 对 6.2 ±1.9 dyn/cm 2, P = 0.016 ) 。另外,有 PD 的病人有更高大动脉的紧张和大动脉的僵硬索引(13.4%±6.4% 对 7.4%±3.6% , P <0.001 和 7.3 ±1.5 对 4.9 ±1.9, P <0.001 分别地) 。而且,浆液 homocysteine 层次被发现断然与大动脉的僵硬索引被相关,在浆液 homocysteine 的大动脉的膨胀性和层次之间有否定关联(r = 0.674, P <0.001;r =− 0.602, P <0.001,分别地) 有在 L-dopa 治疗下面的 PD 的 .ConclusionsThe 病人增加了大动脉的僵硬并且与健康个人相比损害了心脏舒张的功能。提高的浆液 homocysteine 层次可以是可能的 pathophysiological 机制。Zeki Yuksel Gunaydln Fahriye Feriha Ozer Ahmet Karagoz Osman Bektas Mehmet Baran Karatas Ash Vural Adil Bayramoglu Abdullah Celik Mehmet Yaman 2016Journal of Geriatric Cardiology2016,13,1:3
11Colorectal stenting for palliation and as a bridge to surgery:A 5-year follow-up study显示文摘AIM: To evaluate the long-term effectiveness of colonic stents in colorectal tumors causing large bowel obstruction.METHODS: We retrospectively analyzed data from 49 patients with colorectal cancer who had undergone colorectal stent placement between January 2008 and January 2013. Patients' symptoms,characteristics and clinicopathological data were obtained by reviewing medical records. The obstruction was diagnosed clinically and radiologically. Histopathological diagnosis was achieved endoscopically. Technical success rate(TSR)was defined as the ratio of patients with correctly placed SEMS upon stent deployment across the entire stricture length to total number of patients. Clinical success rate(CSR) was defined as the ratio of patients with technical success and successful maintenance of stent function before elective surgery(regardless of number of SEMS deployed) to total number of patients. The surgical success rate(SSR) of colorectal stent as a bridge to surgery was defined as the ratio of patients with successful surgical procedures. Unsuccessful surgical outcomes were defined as being due to insufficient colonic decompression. The technical,clinical,surgical success rates and complications after stenting were assessed.RESULTS: The median age of patients was 64(36 to 89). 44.9% of patients were male and 55.1% were female. Eighteen patients had the obstruction located in the rectum,15 patients in the rectosigmoid region,10 patients in the sigmoid region,and 6 patients had a tumor causing obstruction in the proximal colon. Each patient was categorized pathologically as stage 2(32.7%,16 patients) or stage 3(42.9%,21 patients) and 12 patients(24.4%) had metastatic disease. None of the patients received chemotherapy before stenting. Stenting was undertaken in 37 patients as a bridge to surgery,and in 12 patients stents were used for palliation. Median time to surgery after stenting was 30 ± 91.9 d. All surgery was completed in one single operation and thus no colostomy with stoma was needed. The median overall survival rate of patients with stage 2-3 colorectal cancer was 53.1 mo and stage 4 was 37.1 mo(P = 0.04). Metastatic colorectal patients who were treated palliatively with stents had backbone chemotherapy with oxaliplatin and/or irinotecan-based regimens plus antiangiogenic therapies,especially bevacizumab. Resolution of the obstruction and clinical improvement was achieved in all patients. The technical,clinical and surgical success rates were 95.9%,100% and 94.6%,respectively.CONCLUSION: The efficacy and safety of colonic stents was demonstrated both as a bridge to surgery and for palliative decompression. In addition,results emphasize the importance of the skills of the endoscopist in colonic stenting.Baris Bayraktar Ibrahim Ali Ozemir Umut Kefeli Gokhan Demiral Julide Sagiro?lu Onur Bayraktar Gupse Adali Alp Ozcelik Osman Baran Tortum 2015World Journal of Gastroenterology2015,21,31:3
12Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation.Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? 2014World Journal of Gastroenterology2014,20,25:3
13Gastroesophageal reflux in asymptomatic obese subjects:An esophageal impedance-pH study显示文摘AIM:To investigate the relationship between reflux and body mass index(BMI) in the asymptomatic obese population using the impedance-p H technique.METHODS:Gastroesophageal reflux is frequent in the obese population.However,the relationship between acid reflux and BMI in asymptomatic obese people is unclear.Forty-six obese(BMI > 25 kg/m2) people were enrolled in this prospective study.We evaluated the demographic findings and 24-h impedance p H values of the whole group.Gas,acid(p H < 4),weak acid(p H = 4-7) and weak alkaline(p H ≥ 7) reflux parameters were analyzed.RESULTS:The mean age of patients was 49.47±12.24 years,and half of them were men.The mean BMI was 30.64±3.95 kg/m2(25.14-45.58 kg/m2).BMI of 23 was over 30 kg/m2.Seventeen patients had a comorbidity(hypertension,diabetes mellitus,or ischemic heart disease).Endoscopic examination revealed esophagitis in 13 of the 28 subjects(10Grade A,3 Grade B).The subjects were divided into two groups according to BMI(<30 and>30 kg/m2).Demographic and endoscopic findings,and impedance results were similar in these two groups.However,there was a positive correlation between BMI and total and supine p H<4 episodes(P=0.002,r=0.414;P=0.000,r=0.542),p H<4 reflux time(P=0.015,r=0.319;P=0.003,r=0.403),and De Meester score(P=0.012,r=0.333).CONCLUSION:Acid reflux is correlated with BMI in asymptomatic obese individuals.Filiz Akyüz Ahmet Uyanikoglu Fatih Ermis Serpil Arici ümit Akyüz Divison of Gastroenterology Department of Internal Medicine Faculty of Medicine Yeditepe University Bülent Baran Binnur Pinarbasi Nurdan Gul 2015World Journal of Gastroenterology2015,21,10:3
14一种生态友好的皮胶原固定方法—麻疯树籽油作为协同鞣剂的作用显示文摘采用麻疯树籽油作为协同鞣剂,与植物鞣剂共同应用于皮革鞣制中,克服了传统植鞣法中的大部分缺点。对鞣制系统的不同工艺参数进行研究。采用柔软测试仪对柔软性的改善效果量化。同时,采用新鲜成熟的真菌,如黑曲霉、黄曲霉和木霉菌作为接种物,考察鞣革的抗菌效果。研究表明,采用麻疯树籽油和植物鞣剂共同鞣制的新型鞣法,是一种利用可再生能源的可行性鞣法。Victor John Sundar Chellappa Muralidharan Asit Baran Mandal 陈小珂(译) 2015中国皮革2015,44,3:3
15Human adipose derived stem cells are superior to human osteoblasts (HOB) in bone tissue engineering on a collagen-fibroin-ELR blend显示文摘The ultrastructure of the bone provides a unique mechanical strength against compressive, torsional andtensional stresses. An elastin-like recombinamer (ELR) with a nucleation sequence for hydroxyapatitewas incorporated into films prepared from a collagen-silk fibroin blend carrying microchannel patternsto stimulate anisotropic osteogenesis. SEM and fluorescence microscopy showed the alignment ofadipose-derived stem cells (ADSCs) and the human osteoblasts (HOBs) on the ridges and in the groovesof microchannel patterned collagen-fibroin-ELR blend films. The Young's modulus and the ultimatetensile strength (UTS) of untreated films were 0.58 ± 0.13 MPa and 0.18 ± 0.05 MPa, respectively. After 28days of cell culture, ADSC seeded film had a Young's modulus of 1.21 ± 0.42 MPa and UTS of0.32 ± 0.15 MPa which were about 3 fold higher than HOB seeded films. The difference in Young'smodulus was statistically significant (p: 0.02). ADSCs attached, proliferated and mineralized better thanthe HOBs. In the light of these results, ADSCs served as a better cell source than HOBs for bone tissueengineering of collagen-fibroin-ELR based constructs used in this study. We have thus shown theenhancement in the tensile mechanical properties of the bone tissue engineered scaffolds by usingADSCs.Esen Sayin Rosti Hama Rashid JoséCarlos Rodríguez-Cabello Ahmed Elsheikh Erkan Türker Baran Vasif Hasirci 2017Bioactive Materials2017,2,2:2
16Assessment of traffic performance measures and safety based on driver age and experience:A microsimulation based analysis for an unsignalized T-intersection显示文摘Traffic safety and performance measures such as crash risk and queue lengths or travel times are influenced by several important factors including those related to environment,human,and roadway design,especially at intersections.Previous research has studied different aspects related to these factors,yet these characteristics are not fully investigated with a focus on age and experience of drivers.In this paper,we investigate this issue by using a two-phase approach via a case study application on a critical T-intersection in the City of Tallahassee,Florida.The first phase includes a scenario-based microsimulation analysis through the use of a microscopic simulation software,namely VISSIM,to illustrate the variations in traffic performance measures with respect to driver compositions of different age groups in the traffic stream.A variety of scenarios is created where the driving characteristics are provided as inputs to these scenarios in terms of decision making and risk taking.This is also supported by a sensitivity analysis conducted based on the driver composition in the traffic.The second phase includes the analysis of microsimulation outputs via a tool developed by Federal Highway Administration tool,namely the Surrogate Safety Assessment Model(SSAM),in order to determine the traffic conflicts that occur in each scenario.These conflicts are also compared with real-life crash data for validation purposes.Results show that(a) the differences in risk perception that affect driving behavior might be significant in influencing traffic safety and performance measures,and(b) the proposed approach is considerably successful in simulating the actual crash conflict points.Mehmet Baran Ulak Eren Erman Ozguven Ren Moses Thobias Sando Walter Boot Yassir AbdelRazig John Olusegun Sobanjo 2019Journal of Traffic and Transportation Engineering(English Edition)2019,6,5:2
17Energy Aspects of CO_2 Sorption in the Context of Sequestration in Coal Deposits显示文摘This paper summarises the results of experimental testing of carbon dioxide sorption on five coal samples. Sorption tests were done at the temperature 288, 298, 313 and 323 K, in the pressure range 0–5 MPa. The analysis of sorption isotherms and the effects of temperature on sorption capacity reveal that in the case of samples NR1, Pn, Tu, Be the temperature increase from 298 to 323 K led to 1.3-fold decrease of the sorption value. In the case of coal Th the decrease of sorption capacity was 3-fold. It appears that the analysis of maceral content plays a major role. In the case of coals, porosity is associated with the petrographic composition. The values of the isosteric heat of sorption and the work of expansion and desorption were derived for the investigated sorption systems. Test data reveal that for hard coals the isosteric heat is inversely proportional to the 'reserve' of volumetric work—a major parameter triggering the sudden release of gas from the coalbed, thus enabling us to assess the potential risk involved in rapid unsealing of the coalbed.Pawe Baran Katarzyna Zarebska Adam Nodzeński 2014Journal of Earth Science2014,25,4:2
18Ingested gastrointestinal foreign bodies: predisposing factors for complications in children having surgical or endoscopic removal显示文摘Baran Tokar Alper A. Cevik Huseyin Ilhan 2007Pediatric Surgery International2007,,2:2
19Guanylyl Cyclase C Suppresses Intestinal Tumorigenesis by Restricting Proliferation and Maintaining Genomic Integrity显示文摘Peng Li Stephanie Schulz Alessandro Bombonati Juan P. Palazzo Terry M. Hyslop Yihuan Xu Amy A. Baran Linda D. Siracusa Giovanni M. Pitari Scott A. Waldman 2007Gastroenterology2007,,2:2
20A transaction assessment method for allocation of transmission services 显示文摘BARAN M E BANUNARRYANAN V GARREN K E 1999IEEE Trans on Power Systems1999,14,3:2
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