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1Effect of preoperative immunonutrition and other nutrition models on cellular immune parameters显示文摘AIM:To evaluate the effects of preoperative immunonutrition and other nutrition models on the cellular immunity parameters of patients with gastrointestinal tumors before surgical intervention.In addition,effects on postoperative complications were examined. METHODS:Patients with gastrointestinal tumors were randomized into 3 groups.The immunonutrition group received a combination of arginine,fatty acids and nucleotides.The second and third group received normal nutrition and standard enteral nutrition,respectively.Nutrition protocols were administered for 7 d prior to the operation.Nutritional parameters,in particular prealbumin levels and lymphocyte subpopulations(CD4+,CD8+,CD16+/56+,and CD69 cells)were evaluated before and after the nutrition protocols.Groups were compared in terms of postoperative complications and duration of hospital stay. RESULTS:Of the 42 patients who completed thestudy,16 received immunonutrition,13 received normal nutrition and 13 received standard enteral nutrition. prealbumin values were low in every group,but this parameter was improved after the nutritional protocol only in the immunonutrition group(13.64±8.83 vs 15.98±8.66,P=0.037).Groups were similar in terms of CD4+,CD16+/56,and CD69+prior to the nutritional protocol;whereas CD8+was higher in the standard nutrition group compared to the immunonutrition group.After nutritional protocols,none of the groups had an increase in their lymphocyte subpopulations.Also,groups did not differ in terms of postoperative complications and postoperative durations of hospital stay. CONCLUSION:Preoperative immunonutrition provided a significant increase in prealbumin levels,while it did not significantly alter T lymphocyte subpopulation counts,the rate of postoperative complications and the duration of hospital stay.Yusuf Gunerhan Neset Koksal Umit Yasar Sahin Mehmet Ali Uzun Emel Ek■ioglu-Demiralp 2009World Journal of Gastroenterology2009,15,4:21
2Intraperitoneal chemotherapy and its evolving role in management of gastric cancer with peritoneal metastases显示文摘Advanced gastric cancer(GC) has been recognized as lethal disease when peritoneal metastases(PM) occurred.There is no standard treatment for advanced GC with PM.Until 1980s,the therapeutic arena for these patients had remained stagnant,with no therapeutic approach having shown a survival gain in GC with PM.However,cytoreductive surgery(CRS) with peritonectomy procedures and intraperitoneal chemotherapy(IPC) promising new combined therapeutic approach to achieve disease control for GC with PM.The recent publications changed the GC with PM treatment landscape by providing an evidence that CRS and IPC led to prolongation in overall survival(OS).This review will provide an overview of the evolving role of CRS and IPC in the management of advanced GC with PM in the current era.Emel Canbay Yutaka Yonemura Bjorn Brucher Seung Hyuk Baik Paul H.Sugarbaker 2014Chinese Journal of Cancer Research2014,26,1:10
3Effects of estrogen replacement therapy on apoptosis and vascular endothelial growth factor expression in ocular surface epithelial cells:An experimental study显示文摘AIM:To investigate the effects of estrogen replacement therapy (ERT) on apoptosis and vascular endothelial growth factor (VEGF) expression in ocular surface in an experimental rat model.· METHODS:Forty female,Wistar rats were randomized in 4 groups in the study.Subcutaneous ERT (17β-estradiol,10g/kg/day) was administered to the first group without ovariectomy and to the second group with ovariectomy for three months.Third group had only ovariectomy and fourth group had sham operation.All rats were sacrificed in estrous cycles determined by vaginal smear test and their right eyes were enucleated at the end of the third month.Enucleated eyes were analyzed by immunohistochemical method for expressions of caspase-3,bcl-2,VEGF and TUNEL assay.· RESULTS:Caspase-3 expression of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.005),and group 2 (P =0.007).TUNEL score of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.006).TUNEL score of corneal epithelium was significantly higher in group 3 than group 2 (P =0.012),and group 4 (P =0.002).There was no significant difference between groups in that bcl-2 and VEGF expressions.· CONCLUSION:We determined increased apoptosis in ocular surface epithelial cells in ovariectomized rats.ERT and endogen estrogen decreased the apoptosis,and did not result in difference in VEGF expression between the groups.Estrogen may be beneficial for the treatment of apoptosis-mediated ocular surface disorders such as dry eye.Further studies are needed on this subject for a better understanding of the role of estrogen and to provide a new insight for treatment and prevention of apoptosis-mediated ocular surface disorders.Fatih zcura Sema Oru Dndar Emel Dikicioglu etin Nahit Beder Mehmet Dndar 2012International Journal of Ophthalmology(English edition)2012,5,1:7
4New treatment modalities in Alzheimer’s disease显示文摘Alzheimer’s disease (AD) is still a major public health challenge without an effective treatment to prevent or stop it. Routinely used acetylcholinesterase inhibitors and memantine seem to slow disease progression only to a limited extend. Therefore, many investigations on new drugs and other treatment modalities are ongoing in close association with increasing knowledge of the pathophysiology of the disease. Here, we review the studies about the new treatment modalities in AD with a classification based on their main targets, specifically pathologic structures of the disease, amyloid and tau, neural network dysfunction with special interest to the regulation of gamma oscillations, and attempts for the restoration of neural tissue via regenerative medicine. Additionally, we describe the evolving modalities related to gut microbiota, modulation, microglial function, and glucose metabolism.Emel Koseoglu 2019World Journal of Clinical Cases2019,7,14:7
5Structure-property relationships in ILs: A study of the alkyl chain length dependence in vaporisation enthalpies of pyridinium based ionic liquids显示文摘The enthalpies of vaporization for the series of pyridinium-based ionic liquids with bis(trifluoromethylsulfonyl)imide anion [CnPy][NTf2] (n = 2, 3, 4, 5, and 6) have been determined with the quartz crystal microbalance technique combined with the Langmuir evaporation. The linear dependence of vaporization enthalpies on the chain length has been revealed. New approach based on volumetric, surface tension, and speed of sound measurements has been developed for estimation of heat capacity differences between gas and liquid phase, which were required for adjustment of measured vaporization enthalpies to the ref- erence temperature 298 K.ZAITSAU Dzmitry H. YERMALAYEU Andrei V. EMEL'YANENKO Vladimir N. VEREVKIN Sergey P. WELZ-BIERMANN Urs SCHUBERT Thomas 2012Science China Chemistry2012,55,8:4
6Association of Apolipoprotein E Polymorphisms in Patients with Non-Alcoholic Steatohepatitis显示文摘Ali Sazci Gurler Akpinar Cem Aygun Emel Ergul Omer Senturk Sadettin Hulagu 2008Digestive Diseases and Sciences2008,,12:3
7Dynamics of circulating microparticles in chronic kidney disease and transplantation:Is it really reliable marker?显示文摘The deterioration of endothelial structure plays a very important role in the development of vascular diseases. It is believed that endothelial dysfunction starts in the early stage of kidney disease and is a risk factor of an unfavorable cardiovascular prognosis. Because a direct assessment of biological states in endothelial cells is not applicable, the measurement of endothelial microparticles(EMPs) detached from endothelium during activation or apoptosis is thought to be a marker of early vascular disease and endothelial dysfunction in children with chronic kidney disease(CKD). Few studies have shown increased circulating EMPs and its relationship with cardiovascular risk factors in patients with CKD.MPs contain membrane proteins and cytosolic material derived from the cell from which they originate. EMPs having CD144, CD 146, CD31+/CD41-, CD51 and CD105 may be used to evaluate the vascular endothelial cell damage and determine asymptomatic patients who might be at higher risk of developing cardiovascular disease in CKD and renal transplant.Ismail Dursun Sibel Yel Emel Unsur 2015World Journal of Transplantation2015,5,4:3
8Dissimilar friction welding of 6061-T6 aluminum and AISI 1018 steel: Properties and microstructural characterization显示文摘Emel Taban Jerry E. Gould John C. Lippold 2009Materials and Design2009,,5:2
9Gastric Necrosis and Perforation Caused by Acute Gastric Dilatation: Report of a Case显示文摘Mustafa Turan Metin ?en Emel Canbay Kursat Karadayi Esin Yildiz 2003Surgery Today2003,,4:2
10Preoperative Carcinoembryonic Antigen Level Predicts Prognosis in Patients with Pseudomyxoma Peritonei Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy显示文摘Emel Canbay Haruaki Ishibashi Shouzou Sako Akiyoshi Mizumoto Masamitsu Hirano Masumi Ichinose Nobuyuki Takao Yutaka Yonemura 2013World Journal of Surgery2013,,6:2
11Percutaneous imaging-guided treatment of hydatid liver cysts: Do long-term results make it a first choice?显示文摘Adnan Kabaalio?lu Ka?an ?eken Emel Alimoglu Ali Apaydin 2006European Journal of Radiology2006,,1:2
12Differentiating a large abdominal cystic lymphangioma from multicystic mesothelioma: report of a case显示文摘Hiroshi Nagata Yutaka Yonemura Emel Canbay Haruaki Ishibashi Makoto Narita Makio Mike Nobuyasu Kano 2014Surgery Today2014,,7:2
13The rs2228570 Variant of the Vitamin D Receptor Gene is Associated with Essential Tremor显示文摘Dear Editor,Essential tremor(ET)is one of the most common movement disorders of unknown etiology[1,2],having an overall prevalence of 4%in the general population[2].The age at onset has been reported to be between 15 years and 20 years,and penetrance to be complete at between50 years and 70 years.It seems to be a progressive neurological disorder,and can lead to substantial disability in some patients.Although it presents some degree of clinical variability,it occurs in sporadic(SET)and familial(FET)forms with heterogeneity of expression between and within families[3].ET is characterized essentially by a postural and kinetic tremor most often affecting the arms,but it can also affect other parts of the body[4].Nonetheless,familial expression of ET has been linked to some loci[5–7].Ali Sazci Nihal Uren Halil Atilla Idrisoglu Emel Ergul 2019Neuroscience Bulletin2019,35,2:2
141,3-bis(-aminopropyl)tetramethyldisiloxane modified epoxy resins:curing and characterization显示文摘EMEL Y ISKENDER Y 1998Polymer1998,39,89:1
157-year survey after percutaneous dilatational tracheotomy on a medical intensive care unit显示文摘PIA L ANNEMARIE S EMEL G 2010J Investigat Med2010,58,8:1
16Effects of Pentoxifylline on TNF-α Production by Peripheral Blood Mononuclear Cells in Patients with Nonalcoholic Steatohepatitis显示文摘Deniz G. Duman Filiz Ozdemir Esra Birben Ozlem Keskin Emel Ek?io?lu-Demiralp Cigdem Celikel Omer Kalayci Cem Kalayci 2007Digestive Diseases and Sciences2007,,10:1
17The manufacture of microencapsulated phase change materials suitable for the design of thermally enhanced fabrics显示文摘Nihal Sarier Emel Onder 2007Thermochimica Acta2007,452,:1
18Laboratory method for rating the effectiveness of detergent additives in automotive gasolines显示文摘V. E. Emel’yanov S. K. Kyuregyan K. B. Rudyak 1981Chemistry and Technology of Fuels and Oils1981,,8:1
19Interactions of some Schiff base compounds with mild steel surface in hydrochloric acid solution显示文摘Emel Bayol Tijen G i rten Ali G rten A 2008Materials Chemistry and Physics2008,,6:1
20Local fracture of thin metallic films during electromagnetic loading显示文摘Emel Y O A 2008Technical Physics2008,53,7:1
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