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| 1 | Effect of preoperative immunonutrition and other nutrition models on cellular immune parameters显示文摘AIM:To evaluate the effects of preoperative immunonutrition and other nutrition models on the cellular immunity parameters of patients with gastrointestinal tumors before surgical intervention.In addition,effects on postoperative complications were examined. METHODS:Patients with gastrointestinal tumors were randomized into 3 groups.The immunonutrition group received a combination of arginine,fatty acids and nucleotides.The second and third group received normal nutrition and standard enteral nutrition,respectively.Nutrition protocols were administered for 7 d prior to the operation.Nutritional parameters,in particular prealbumin levels and lymphocyte subpopulations(CD4+,CD8+,CD16+/56+,and CD69 cells)were evaluated before and after the nutrition protocols.Groups were compared in terms of postoperative complications and duration of hospital stay. RESULTS:Of the 42 patients who completed thestudy,16 received immunonutrition,13 received normal nutrition and 13 received standard enteral nutrition. prealbumin values were low in every group,but this parameter was improved after the nutritional protocol only in the immunonutrition group(13.64±8.83 vs 15.98±8.66,P=0.037).Groups were similar in terms of CD4+,CD16+/56,and CD69+prior to the nutritional protocol;whereas CD8+was higher in the standard nutrition group compared to the immunonutrition group.After nutritional protocols,none of the groups had an increase in their lymphocyte subpopulations.Also,groups did not differ in terms of postoperative complications and postoperative durations of hospital stay. CONCLUSION:Preoperative immunonutrition provided a significant increase in prealbumin levels,while it did not significantly alter T lymphocyte subpopulation counts,the rate of postoperative complications and the duration of hospital stay. | Yusuf Gunerhan Neset Koksal Umit Yasar Sahin Mehmet Ali Uzun Emel Ek■ioglu-Demiralp | 2009 | World Journal of Gastroenterology2009,15,4: | 21 |
| 2 | Intraperitoneal chemotherapy and its evolving role in management of gastric cancer with peritoneal metastases显示文摘Advanced gastric cancer(GC) has been recognized as lethal disease when peritoneal metastases(PM) occurred.There is no standard treatment for advanced GC with PM.Until 1980s,the therapeutic arena for these patients had remained stagnant,with no therapeutic approach having shown a survival gain in GC with PM.However,cytoreductive surgery(CRS) with peritonectomy procedures and intraperitoneal chemotherapy(IPC) promising new combined therapeutic approach to achieve disease control for GC with PM.The recent publications changed the GC with PM treatment landscape by providing an evidence that CRS and IPC led to prolongation in overall survival(OS).This review will provide an overview of the evolving role of CRS and IPC in the management of advanced GC with PM in the current era. | Emel Canbay Yutaka Yonemura Bjorn Brucher Seung Hyuk Baik Paul H.Sugarbaker | 2014 | Chinese Journal of Cancer Research2014,26,1: | 10 |
| 3 | Effects of estrogen replacement therapy on apoptosis and vascular endothelial growth factor expression in ocular surface epithelial cells:An experimental study显示文摘AIM:To investigate the effects of estrogen replacement therapy (ERT) on apoptosis and vascular endothelial growth factor (VEGF) expression in ocular surface in an experimental rat model.· METHODS:Forty female,Wistar rats were randomized in 4 groups in the study.Subcutaneous ERT (17β-estradiol,10g/kg/day) was administered to the first group without ovariectomy and to the second group with ovariectomy for three months.Third group had only ovariectomy and fourth group had sham operation.All rats were sacrificed in estrous cycles determined by vaginal smear test and their right eyes were enucleated at the end of the third month.Enucleated eyes were analyzed by immunohistochemical method for expressions of caspase-3,bcl-2,VEGF and TUNEL assay.· RESULTS:Caspase-3 expression of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.005),and group 2 (P =0.007).TUNEL score of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.006).TUNEL score of corneal epithelium was significantly higher in group 3 than group 2 (P =0.012),and group 4 (P =0.002).There was no significant difference between groups in that bcl-2 and VEGF expressions.· CONCLUSION:We determined increased apoptosis in ocular surface epithelial cells in ovariectomized rats.ERT and endogen estrogen decreased the apoptosis,and did not result in difference in VEGF expression between the groups.Estrogen may be beneficial for the treatment of apoptosis-mediated ocular surface disorders such as dry eye.Further studies are needed on this subject for a better understanding of the role of estrogen and to provide a new insight for treatment and prevention of apoptosis-mediated ocular surface disorders. | Fatih zcura Sema Oru Dndar Emel Dikicioglu etin Nahit Beder Mehmet Dndar | 2012 | International Journal of Ophthalmology(English edition)2012,5,1: | 7 |
| 4 | New treatment modalities in Alzheimer’s disease显示文摘Alzheimer’s disease (AD) is still a major public health challenge without an effective treatment to prevent or stop it. Routinely used acetylcholinesterase inhibitors and memantine seem to slow disease progression only to a limited extend. Therefore, many investigations on new drugs and other treatment modalities are ongoing in close association with increasing knowledge of the pathophysiology of the disease. Here, we review the studies about the new treatment modalities in AD with a classification based on their main targets, specifically pathologic structures of the disease, amyloid and tau, neural network dysfunction with special interest to the regulation of gamma oscillations, and attempts for the restoration of neural tissue via regenerative medicine. Additionally, we describe the evolving modalities related to gut microbiota, modulation, microglial function, and glucose metabolism. | Emel Koseoglu | 2019 | World Journal of Clinical Cases2019,7,14: | 7 |
| 5 | Structure-property relationships in ILs: A study of the alkyl chain length dependence in vaporisation enthalpies of pyridinium based ionic liquids显示文摘The enthalpies of vaporization for the series of pyridinium-based ionic liquids with bis(trifluoromethylsulfonyl)imide anion [CnPy][NTf2] (n = 2, 3, 4, 5, and 6) have been determined with the quartz crystal microbalance technique combined with the Langmuir evaporation. The linear dependence of vaporization enthalpies on the chain length has been revealed. New approach based on volumetric, surface tension, and speed of sound measurements has been developed for estimation of heat capacity differences between gas and liquid phase, which were required for adjustment of measured vaporization enthalpies to the ref- erence temperature 298 K. | ZAITSAU Dzmitry H. YERMALAYEU Andrei V. EMEL'YANENKO Vladimir N. VEREVKIN Sergey P. WELZ-BIERMANN Urs SCHUBERT Thomas | 2012 | Science China Chemistry2012,55,8: | 4 |
| 6 | Association of Apolipoprotein E Polymorphisms in Patients with Non-Alcoholic Steatohepatitis显示文摘 | Ali Sazci Gurler Akpinar Cem Aygun Emel Ergul Omer Senturk Sadettin Hulagu | 2008 | Digestive Diseases and Sciences2008,,12: | 3 |
| 7 | Dynamics of circulating microparticles in chronic kidney disease and transplantation:Is it really reliable marker?显示文摘The deterioration of endothelial structure plays a very important role in the development of vascular diseases. It is believed that endothelial dysfunction starts in the early stage of kidney disease and is a risk factor of an unfavorable cardiovascular prognosis. Because a direct assessment of biological states in endothelial cells is not applicable, the measurement of endothelial microparticles(EMPs) detached from endothelium during activation or apoptosis is thought to be a marker of early vascular disease and endothelial dysfunction in children with chronic kidney disease(CKD). Few studies have shown increased circulating EMPs and its relationship with cardiovascular risk factors in patients with CKD.MPs contain membrane proteins and cytosolic material derived from the cell from which they originate. EMPs having CD144, CD 146, CD31+/CD41-, CD51 and CD105 may be used to evaluate the vascular endothelial cell damage and determine asymptomatic patients who might be at higher risk of developing cardiovascular disease in CKD and renal transplant. | Ismail Dursun Sibel Yel Emel Unsur | 2015 | World Journal of Transplantation2015,5,4: | 3 |
| 8 | Dissimilar friction welding of 6061-T6 aluminum and AISI 1018 steel: Properties and microstructural characterization显示文摘 | Emel Taban Jerry E. Gould John C. Lippold | 2009 | Materials and Design2009,,5: | 2 |
| 9 | Gastric Necrosis and Perforation Caused by Acute Gastric Dilatation: Report of a Case显示文摘 | Mustafa Turan Metin ?en Emel Canbay Kursat Karadayi Esin Yildiz | 2003 | Surgery Today2003,,4: | 2 |
| 10 | Preoperative Carcinoembryonic Antigen Level Predicts Prognosis in Patients with Pseudomyxoma Peritonei Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy显示文摘 | Emel Canbay Haruaki Ishibashi Shouzou Sako Akiyoshi Mizumoto Masamitsu Hirano Masumi Ichinose Nobuyuki Takao Yutaka Yonemura | 2013 | World Journal of Surgery2013,,6: | 2 |
| 11 | Percutaneous imaging-guided treatment of hydatid liver cysts: Do long-term results make it a first choice?显示文摘 | Adnan Kabaalio?lu Ka?an ?eken Emel Alimoglu Ali Apaydin | 2006 | European Journal of Radiology2006,,1: | 2 |
| 12 | Differentiating a large abdominal cystic lymphangioma from multicystic mesothelioma: report of a case显示文摘 | Hiroshi Nagata Yutaka Yonemura Emel Canbay Haruaki Ishibashi Makoto Narita Makio Mike Nobuyasu Kano | 2014 | Surgery Today2014,,7: | 2 |
| 13 | The rs2228570 Variant of the Vitamin D Receptor Gene is Associated with Essential Tremor显示文摘Dear Editor,Essential tremor(ET)is one of the most common movement disorders of unknown etiology[1,2],having an overall prevalence of 4%in the general population[2].The age at onset has been reported to be between 15 years and 20 years,and penetrance to be complete at between50 years and 70 years.It seems to be a progressive neurological disorder,and can lead to substantial disability in some patients.Although it presents some degree of clinical variability,it occurs in sporadic(SET)and familial(FET)forms with heterogeneity of expression between and within families[3].ET is characterized essentially by a postural and kinetic tremor most often affecting the arms,but it can also affect other parts of the body[4].Nonetheless,familial expression of ET has been linked to some loci[5–7]. | Ali Sazci Nihal Uren Halil Atilla Idrisoglu Emel Ergul | 2019 | Neuroscience Bulletin2019,35,2: | 2 |
| 14 | 1,3-bis(-aminopropyl)tetramethyldisiloxane modified epoxy resins:curing and characterization显示文摘 | EMEL Y ISKENDER Y | 1998 | Polymer1998,39,89: | 1 |
| 15 | 7-year survey after percutaneous dilatational tracheotomy on a medical intensive care unit显示文摘 | PIA L ANNEMARIE S EMEL G | 2010 | J Investigat Med2010,58,8: | 1 |
| 16 | Effects of Pentoxifylline on TNF-α Production by Peripheral Blood Mononuclear Cells in Patients with Nonalcoholic Steatohepatitis显示文摘 | Deniz G. Duman Filiz Ozdemir Esra Birben Ozlem Keskin Emel Ek?io?lu-Demiralp Cigdem Celikel Omer Kalayci Cem Kalayci | 2007 | Digestive Diseases and Sciences2007,,10: | 1 |
| 17 | The manufacture of microencapsulated phase change materials suitable for the design of thermally enhanced fabrics显示文摘 | Nihal Sarier Emel Onder | 2007 | Thermochimica Acta2007,452,: | 1 |
| 18 | Laboratory method for rating the effectiveness of detergent additives in automotive gasolines显示文摘 | V. E. Emel’yanov S. K. Kyuregyan K. B. Rudyak | 1981 | Chemistry and Technology of Fuels and Oils1981,,8: | 1 |
| 19 | Interactions of some Schiff base compounds with mild steel surface in hydrochloric acid solution显示文摘 | Emel Bayol Tijen G i rten Ali G rten A | 2008 | Materials Chemistry and Physics2008,,6: | 1 |
| 20 | Local fracture of thin metallic films during electromagnetic loading显示文摘 | Emel Y O A | 2008 | Technical Physics2008,53,7: | 1 |