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| 1 | Association of CagA and VacA presence with ulcer and non-ulcer dyspepsia in a Turkish population显示文摘AIM: The mostly known genotypic virulence features, of H. pyloriare cytotoxin associated gene A (ragA) and Vacuolating cytotoxin gene A (VacA). We investigated the association of these major virulence factors with ulcer and non-ulcer dyspepsia in our region.METHODS: One hundred and forty two dyspeptic patients were studied (average age 44.8±15.9 years, range 15-87years, 64 males and 78 females). Antral and corpus biopsies were taken for detecting and genotyping of H. pylori. 107patients who were H. pylori positive by histological assessment were divided into three groups according to endoscopic findings: Duodenal ulcer (DU), gastric ulcer (GU)and non-ulcer dyspepsia (NUD). The polymerase chain reaction (PCR) was used to detect CagA and VacA genes of H.pylori using specific primers.RESULTS: H.pyloriwas isolated from 75.4 % (107/142) of the patients. Of the 107 patients, 66 (61.7 %) were cagApositive and 82 (76.6 %) were Vacl-positive. CagA gene was positively associated with DU and GU (P<0.01, P<0.02),but not with NUD (P>0.05). Although VacA positivity in ulcer patients was higher than that in NUD group, the difference was not statistically significant (P>0.05).CONCLUSION: There is a significantly positive association between CagA genes and DU and GU. The presence of VacA is not a predictive marker for DU, GU, and NUD in our patients. | Kantarceken Bulent Aladag Murat Atik Esin Koksal Fatih Harputluoglu MMMurat Harputluoglu Hakan Karincaoglu Melih Ares Mehmet Yildirim Bulent Hilmioglu Fatih | 2003 | World Journal of Gastroenterology2003，9，7： | 8 |
| 2 | Meshless Method for Analysis of Permeable Breakwaters in the Proximity of A Vertical Wall显示文摘In the present work, the improved version of the meshless singular boundary method(ISBM) is developed for analyzing the performance of bottom standing submerged permeable breakwaters in regular normally incident waves and in the proximity of a vertical wall. Both single and dual prismatic breakwaters of rectangular and trapezoidal forms are examined. The physical problem is cast in terms of the Laplace equation governing an irrotational flow and incompressible fluid motion with appropriate mixed type boundary conditions, and solved numerically using the ISBM. To model the permeability of the breakwaters fully absorbing boundary conditions are assumed. Numerical results are presented in terms of hydrodynamic quantities of the reflection coefficients. These are firstly validated against the results of a multi-domain boundary element method(BEM) developed independently for a previous study. The agreement between the results of the two methods is excellent. The coefficients of reflection are then computed and discussed for a variety of structural conditions including the breakwaters height, width, spacing, and absorbing permeability. Effects of the proximity of the vertical plane wall are also investigated. The breakwater's width is found to have only marginal effects compared with its height. Permeability tends to decrease the minimum reflections. These coefficients show periodic variations with the spacing relative to the wavelength. Trapezoidal breakwaters are found to be more cost-effective than the rectangular breakwaters. Dual breakwater systems are confirmed to perform much better than single structures. | Nadji CHIOUKH Karim OUAZZANE Yal??n YüKSEL Benameur HAMOUDI Esin ?EVIK | 2019 | China Ocean Engineering2019，33，2： | 6 |
| 3 | Reflection and Transmission of Regular Waves from/Through Single and Double Perforated Thin Walls显示文摘In this paper, reflection and transmission coefficients of regular waves from/through perforated thin walls are investigated. Small scale laboratory tests have been performed in a wave flume firstly with single perforated thin Plexiglas plates of various porosities. The plate is placed perpendicular to the flume with the height from the flume bottom to the position above water surface. With this thin wall in the flume wave overtopping is prohibited and incident waves are able to transmit. The porosities of the walls are achieved by perforating the plates with circular holes.Model settings with double perforated walls parallel to each other forming so called chamber system, have been also examined. Several parameters have been used for correlating the laboratory tests' results. Experimental data are also compared with results from the numerical model by applying the multi-domain boundary element method(MDBEM)with linear wave theory. Wave energy dissipation due to the perforations of the thin wall has been represented by a simple yet effective porosity parameter in the model. The numerical model with the MDBEM has been further validated against the previously published data. | Nadji CHIOUKH Esin CEVIK Yalcin YUKSEL | 2017 | China Ocean Engineering2017，31，4： | 4 |
| 4 | Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury显示文摘AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion(IR) model and compare pretreatment and post-treatment use.METHODS: Selenium pre-treatment group(n =8) was treated with intraperitoneal(i.p.) selenium 0.5 mg/kg for7 d and terminated 24 h after the IR injury. Selenium posttreatment group( n = 8) was treated with i. p. selenium0.5 mg/kg for 7d after the IR injury with termination at the end of the 7d period. Sham group(n =8) received i.p.saline injections identical to the selenium volume for 7d with termination 24 h after the IR injury. Control group(n =8) received no intervention. Main outcome measures were retina superoxide dismutase(SOD), glutathione(GSH),total antioxidant status(TAS), malondialdehyde(MDA),DNA fragmentation levels, and immunohistological apoptosis evaluation.RESULTS: Compared to the Sham group, selenium pre-treatment had a statistical difference in all parameters except SOD. Post-treatment selenium also resulted in statistical differences in all parameters except the MDA levels. When comparing selenium groups, the pre-treatment selenium group had a statistically higher success in reduction of markers of cell damage such as MDA and DNA fragmentation. In contrast, the post-selenium treatment group had resulted in statisticallyhigher levels of GSH. Histologically both selenium groups succeeded to limit retinal thickening and apoptosis. Pre-treatment use was statistically more successful in decreasing apoptosis in ganglion cell layer compared to post-treatment use.CONCLUSION: Selenium was successful in retinal protection in IR injuries. Pre-treatment efficacy was superior in terms of prevention of tissue damage and apoptosis. | Alper Yazici Hasan Aksit Esin Sogutlu Sari Arzu Yay Haydar Ali Erken Dilek Aksit Harun Cakmak Kamil Seyrek Sitki Samet Ermis | 2015 | International Journal of Ophthalmology(English edition)2015，8，2： | 3 |
| 5 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016，8，9： | 3 |
| 6 | Inducible nitric oxide synthase and histopathological correlation in chronic viral hepatitis显示文摘 | Esin Atik Yusuf Onlen Lutfu Savas Figen Doran | 2007 | International Journal of Infectious Diseases2007，，1： | 2 |
| 7 | YALIKAVAK精品酒店,博德鲁姆-穆拉,土耳其显示文摘这座40间客房的精品酒店位于博德鲁姆的Yalikavak,美丽的爱琴海沿岸。设计通过在不同层高上交错布置遮蔽、半遮蔽和露天开放区域,营造出呼应场所地形、主导风向和景观的连续空间。 | Suna Birsen-Otay Sevim Aslan Ipek Yurekli Deniz Aslan Arda Inceoglu Kemal Ozmen Ilker Aksoy Ceren Hancioglu Esin Gumus Gunseli Dolluk 项琳斐 | 2010 | 世界建筑2010，，7： | 2 |
| 8 | Gastric Necrosis and Perforation Caused by Acute Gastric Dilatation: Report of a Case显示文摘 | Mustafa Turan Metin ?en Emel Canbay Kursat Karadayi Esin Yildiz | 2003 | Surgery Today2003，，4： | 2 |
| 9 | Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta-defensin-3 显示文摘 | Maisetta G Di Luca M Esin S | 2008 | Peptides2008，29，1： | 1 |
| 10 | Susceptibility of Strepto- coccus mutans and Actinobacillus actinomycetemcomitans to bac- tericidal activity of human beta-defensin 3 in biological fluids 显示文摘 | Maisetta G Batoni G Esin S | 2005 | J Antimicrob Agents Chemother2005，49，3： | 1 |
| 11 | Views on Turkey's impending ESCO market: Is it promising 显示文摘 | Esin Okay Nesrin Okay Konukman | 2008 | En- ergy Policy2008，，36： | 1 |
| 12 | Real-time multiple vehicle detection and tracking from a moving vehicle显示文摘 | Margrit Betke Esin Haritaoglu Larry S. Davis | 2000 | Machine Vision and Applications2000，，2： | 1 |
| 13 | An automatic diabetes diagnosis system based on LDA-Wavelet Support Vector Machine Classifier显示文摘 | Duygu ?ali?ir Esin Do?antekin | 2011 | Expert Systems With Applications2011，，7： | 1 |
| 14 | Diagnosis of liver cirrhosis in children based on colour Doppler ultrasonography with histopathological correlation显示文摘 | Davut Tüney M. Erkin Aribal Deniz Ertem Esin Kotilo?lu Ender Pehlivano?lu | 1998 | Pediatric Radiology1998，，11： | 1 |
| 15 | Rheological characterization of tahin/pekmez (sesame paste/concentrated grape juice) blends显示文摘 | Arslan E Yener ME Esin A | 2005 | Journal of Food Engineering2005，69，2： | 1 |
| 16 | The Microplastic Strain Energy Criterion Applied to Fatigue显示文摘 | Esin A | 1968 | J Basic Engineering1968，90，1： | 1 |
| 17 | Adaptive radiation therapy of breast cancer by repeated imaging during irradiation显示文摘Breast cancer is the most frequent cancer among females and also a leading cause of cancer related mortality worldwide.A multimodality treatment approach may be utilized for optimal management of patients with combinations of surgery,radiation therapy(RT)and systemic treatment.RT composes an integral part of breast conserving treatment,and is typically used after breast conserving surgery to improve local control.Recent years have witnessed significant improvements in the discipline of radiation oncology which allow for more focused and precise treatment delivery.Adaptive radiation therapy(ART)is among the most important RT techniques which may be utilized for redesigning of treatment plans to account for dynamic changes in tumor size and anatomy during the course of irradiation.In the context of breast cancer,ART may serve as an excellent tool for patients receiving breast irradiation followed by a sequential boost to the tumor bed.Primary benefits of ART include more precise boost localization and potential for improved normal tissue sparing with adapted boost target volumes particularly in the setting of seroma reduction during the course of irradiation.Herein,we provide a concise review of ART for breast cancer in light of the literature. | Omer Sager Ferrat Dincoglan Selcuk Demiral Bora Uysal Hakan Gamsiz Fatih Ozcan Onurhan Colak Yelda Elcim Esin Gundem Bahar Dirican Murat Beyzadeoglu | 2020 | World Journal of Radiology2020，12，5： | 1 |
| 18 | Evaluations of heavy metal pollution in sediment and Mullusbarbatus from the lzmir Bay ( Eastern Aegean) during 1997 - 2009 显示文摘 | Filiz K Aynur K Esin U | 2011 | Marine Pollution Bulletin2011，62，7： | 1 |
| 19 | Susceptibility of Streptococ- cus mutans and Actinobacillus actinomycetemcomitans to bacte- ricidal activity of human 13-defensin 3 in biological fluids显示文摘 | Maisetta G Batoni G Esin S et 01 | 2005 | An- timierob Agents Chemother2005，49，3： | 1 |
| 20 | Budget Deficits:Rhetoric and Reality显示文摘 | Robert Esiner | 1989 | Journal of Economic Perspectives1989，，2： | 1 |
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