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| 1 | Corrigendum to “Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis” [Cancer Lett. 328 (2) (2012) 212–221]显示文摘 | Angela L. McCleary-Wheeler Gwen A. Lomberk Frank U. Weiss Günter Schneider Muller Fabbri Tara L. Poshusta Nelson J. Dusetti Sandra Baumgart Juan L. Iovanna Volker Ellenrieder Raul Urrutia Martin E. Fernandez-Zapico | 2013 | Cancer Letters2013，，1： | 2 |
| 2 | The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis显示文摘 | Ortiz EM Dusetti NJ Vasseur S | 1998 | Gastroenterolog1998，114，： | 1 |
| 3 | Lithostathine, an inhibitor of CaCO3 crystal growth in pancreatic juice, induces bacterial aggregation显示文摘 | Iovanna J Frigerio JM Dusetti N | 1993 | Pancreas1993，8，59： | 1 |
| 4 | Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant显示文摘 | Mancardi S Stanta G Dusetti N | 1999 | Experimental Cell Research1999，246，2： | 1 |
| 5 | Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant显示文摘 | Mancardi S Stanta G Dusetti N | 1999 | Experimental Cell Research1999，246，2： | 1 |
| 6 | The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis显示文摘 | Ortiz EM Dusetti NJ Vasseur S | 1998 | Gastroenterology1998，114，4： | 1 |
| 7 | Mechanism of PAP I gene induction during hepatocarcinogenesis: clinical implications显示文摘 | Dusetti NJ Montalto G Ortiz EM | 1996 | Br J cancer1996，74，11： | 1 |
| 8 | An ionizable supramolecular dendrimer nanosystem for effective siRNA delivery with a favorable safety profile显示文摘Gene therapy using small interfering RNA(siRNA)is emerging as a novel therapeutic approach to treat various diseases.However,safe and efficient siRNA delivery still constitutes the major obstacle for clinical implementation of siRNA therapeutics.Here we report an ionizable supramolecular dendrimer vector,formed via self-assembly of a small amphiphilic dendrimer,as an effective siRNA delivery system with a favorable safety profile.By virtue of the ionizable tertiary amine terminals,the supramolecular dendrimer has a low positively charged surface potential and no notable cytotoxicity at physiological pH.Nonetheless,this ionizable feature imparted sufficient surface charge to the supramolecular dendrimer to enable formation of a stable complex with siRNA via electrostatic interactions.The resulting siRNA/dendrimer delivery system had a surface charge that was neither neutral,thus avoiding aggregation,nor too high,thus avoiding cytotoxicity,but was sufficient for favorable cellular uptake and endosomal release of the siRNA.When tested in different cancer cell lines and patient-derived cancer organoids,this dendrimer-mediated siRNA delivery system effectively silenced the oncogenes Myc and Akt2 with a potent antiproliferative effect,outperforming the gold standard vector,Lipofectamine 2000.Therefore,this ionizable supramolecular dendrimer represents a promising vector for siRNA delivery.The concept of supramolecular dendrimer nanovectors via self-assembly is new,yet easy to implement in practice,offering a new perspective for supramolecular chemistry in biomedical applications. | Dinesh Dhumal Wenjun Lan Ling Ding Yifan Jiang Zhenbin Lyu Erik Laurini Domenico Marson Aura Tintaru Nelson Dusetti Suzanne Giorgio Juan Lucio Iovanna Sabrina Pricl Ling Peng | 2021 | Nano Research2021，14，7： | 1 |
| 9 | Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant显示文摘 | Mancardi S Stanta G Dusetti N | 1999 | Exp Cell Res1999，246，2： | 1 |
| 10 | Cloning and expression of the rat vacuole membrane protein I (VMP1) ,a new gene ae tivated in pancreas with acute pancreatitis, which promotes vacuole formation 显示文摘 | Dusetti NJ Jiang Y Vaccaro MI | 2002 | Biochem Biophys Res Cornmun2002，290，2： | 1 |
| 11 | Lymphatic endothelial tumors induced by intraperitoneal injection of incomplete Freund's adjuvant显示文摘 | Mancardi S Stanta G Dusetti N | 1999 | Exp Cell Res1999，246，2： | 1 |
| 12 | The pancreatitis associated protein Ⅲ(PAPⅢ),a new member of the PAP gene family显示文摘 | Frigerio J M Dusetti N J Garrido P | 1993 | Biochim Biophys Acta1993，1216，： | 1 |
| 13 | The pancreatitisassociated protein 1 promoter allows targeting to the pancrease of a foreign gene,whose expression is up-regulated during pancreatic inflammation显示文摘 | Dusetti NJ Vasseur S Ortiz EM | 1997 | J Biol Chem1997，272，9： | 1 |
| 14 | Cloning and expression of the rat vacuole membrane protein 1 (VMPI),a new gene activated in pancreas with acute pancreatitis,which promotes vacuole formation显示文摘 | Dusetti NJ Jiang Y Vaeearo MI | | 0，，02： | 1 |
| 15 | Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation 显示文摘 | Dusetti NJ Jiang Y Vaccaro MI | 2002 | Biochem Biophys Res Commun2002，290，2： | 1 |
| 16 | Cloning and expression of the rat vacuole membrane protein I(VMP1), a new gene activated in pancreas with acute panereatitis, which promotes vacuole formation 显示文摘 | Dusetti N J Jiang Y Vaccaro M l | 2002 | Biochemical and Biophysical Research Communications2002，290，2： | 1 |
| 17 | Cloning and expression of the rat vacuole membrane protein 1 (VMP1) ,a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation显示文摘 | Dusetti NJ Jiang Y Vaccaro MI | 2002 | Biochem Biophys Res Commun2002，290，2： | 1 |
| 18 | Expression profiling in pancreas during the acute phase of pancreatitis using cDNA microarrays显示文摘 | Tomasini R Azizi A | 2000 | Biochem Biophys Res Commun2000，277，3： | 1 |
| 19 | Cloning and expression of the rat vacuole membrane protein 1 (VMP1), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation 显示文摘 | Dusetti NJ Jiang YF Vaecaro MI | 2002 | Biochem Biophys Res Commun2002，290，2： | 1 |
| 20 | Cloning and expression of the rat vacuole membrane protein 1 ( VMP1 ), a new gene activated in pancreas with acute pancreatitis, which promotes vacuole formation 显示文摘 | Dusetti NJ Jiang Y Vaccaro | 2002 | Biochem Biophy Res Commum2002，290，2： | 1 |
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