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| 1 | Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease显示文摘AIM: To investigate the effect of vitamin supplements on homocysteine levels in patients with celiac disease. METHODS: Vitamin B6, folate, vitamin B12, and fasting plasma homocysteine levels were measured in 51 consecutive adults with celiac disease [median (range) age 56 (18-63) years; 40% men, 26 (51%) had villous atrophy, and 25 (49%) used B-vitamin supplements] and 50 healthy control individuals matched for age and sex. Finally, the C677T polymorphism of 5,10-methylene tetrahydrofolate reductase (MTHFR) was evaluated in 46 patients with celiac disease and all control individuals. RESULTS: Patients with celiac disease and using vitamin supplements had higher serum vitamin B6 (P = 0.003),folate (P < 0.001), and vitamin B12 (P = 0.012) levels than patients who did not or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively). Lower plasma homocysteine levels were found in patients using vitamin supplements than in patients who did not (P = 0.001) or healthy controls (P = 0.003). However, vitamin B6 and folate, not vitamin B12, were significantly and independently associated with homocysteine levels. Twenty-four (48%) of 50 controls and 23 (50%) of 46 patients with celiac disease carried the MTHFR thermolabile variant T-allele (P = 0.89). CONCLUSION: Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management. | Muhammed Hadithi Chris JJ Mulder Frank Stam Joshan Azizi J Bart A Crusius Amado Salvador Pea Coen DA Stehouwer Yvo M Smulders | 2009 | World Journal of Gastroenterology2009，15，8： | 3 |
| 2 | Genetic diversity of HCV among various high risk populations(IDAs,thalassemia,hemophilia,HD patients) in Iran显示文摘Objective:To determine the patterns of distribution of HCV genotypes among high risk population in north of Iran.Methods:A cross-sectional study was conducted on 135 HCV RNA-positive high risk individuals including thalassemia,hemophilia,patients under hemodialysis and intravenous drug addicts.HCV genotypes were determined based on amplification with type-specific primers methods.Results:Among the 187 anti-HCV positive samples,only 135 (72.2%)gave HCV-RNA positvity.Over all,the most identified HCV type was genotype 3a(51.1%) followed by 1a(27.4%),1b(8.2%).Sixteen(11.9%)out of 135 HCV RNA-positive participants have infected with more than one genotype or subtypes as follow:1a/1b in 11(8.2%),2/3a in 3 (2.2%),and 1a/1b/3a in 2(1.5%).Stratification of participants revealed that HCV subtype 3a was more prominent in thalassemia,hemophilia and HD patients but 1a and 1b were frequent in intravenous drug addicts.Conclusions:This study is the first report on HCV genotypes among Iranian subjects with different exposure categories resided in Mazandaran.where genotype 3a was found to be the most frequent genotype in thalassemia,hemophilia,and hemodialysis patients but not in IDAs.Since the addiction age is decreasing in Iran and a lot of addicts are IDAs.it might change the subtype pattern of HCV in general population. | Rafiei A Darzyani Azizi M Taheri S Haghshenas MR Hosseinian A Makhlough A | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，7： | 2 |
| 3 | Post-earthquake outbreak of cutaneous leish-maniasis in a rural region of southern Iran 显示文摘 | Fakoorziba MR Baseri A Eghbal F Rezaee S Azizi K Moe- menbellab-Fard MD | 2011 | Ann Trop Med Parasitol2011，105，3： | 1 |
| 4 | Determination of fatty acids and total lipid content in oil seed of 25 pomegranates varieties grown in Iran显示文摘 | Fadavi A Barzegar M Azizi H M | 1998 | J Food Comp Anal1998，，19： | 1 |
| 5 | Imatinib mesylate: an innovation in treatment of autoimmune diseases 显示文摘 | Azizi G Mirshafiey A | 2013 | Recent Pat Inflamm Allergy Drug Diseov2013，7，25： | 1 |
| 6 | Potentialuse of stem cells from bone marrow to repair the extracellular matrix and central nervous system 显示文摘 | PROCKOP D J AZIZI S A COLTER D | 2000 | Biochem Soc Trans2000，28，4： | 1 |
| 7 | Viral peptide immunogens: current challenges and opportunities显示文摘 | Azizi A Diaz-Mitoma F | 2007 | J Pept Sci2007，13，12： | 1 |
| 8 | Pilot study of combined blockade of the renin-angiotensin system in essential hypertensive patients显示文摘 | Azizi M Linhart A Alexander J | 2000 | J Hypertens2000，18，： | 1 |
| 9 | Expert consensus: renal denervation for the treatment of hypertension 显示文摘 | Pathak A Girerd X Azizi M | 2012 | Diagn Interv Imaging2012，93，5： | 1 |
| 10 | Management of hyperthyroidism dur- ing pregnancy and lactation显示文摘 | Azizi F Amouzegar A | 2011 | Eur J Endocrinol2011，164，6： | 1 |
| 11 | Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin Ⅱ-renin feedback interruption显示文摘 | AZIZI M MENARD J BISSERY A | 2004 | J Am Soc Nephrol2004，15，12： | 1 |
| 12 | Tangling effect in fibrillated cellulose reinforced nanocomposites 显示文摘 | Azizi Samir M A S AUoin F Paillet M | 2004 | Macromolecules2004，37，11： | 1 |
| 13 | Electrochemical behavior of gold cyanidation in the presence of a sulfide-rich industrial ore versus its major constitutive sulfide minerals 显示文摘 | AZIZI A PETRE C F OLSEN C LARACHI F | 2010 | Hydrometallurgy2010，101，： | 1 |
| 14 | Electrochemical nucleation and growth of Co and Co-Fe alloys on Pt/Si substrates显示文摘 | SAHARI A AZIZI A SCHMERBER G ABES M BUCHER J P DINIA A | 2006 | Catalysis Today2006，113，34： | 1 |
| 15 | The role of Mycoplasma ovi- pneumoniae and Mycoplasma arginini in pneumonic lungs of slaugh- tered sheep显示文摘 | Azizi S Tajbakhsh E Rezaii A | 2011 | Revue M6diclne V6terinare2011，162，： | 1 |
| 16 | Leveraging strategies to increase gold cyanidation in the presence of sulfide minerals-- Packed bed electrochemical reactor approach 显示文摘 | AZIZI A PETRE C F LARACHI F | 2012 | Hydrometallurgy2012，11，： | 1 |
| 17 | Effect of microencapsulation and resistant starch on the probiotic survival and sensory properties of synbiotic ice cream显示文摘 | HOMAYOUNI A AZIZI A EHSANI M R | 2008 | Food Chemistry2008，111，1： | 1 |
| 18 | Effects of CB1 receptor antagonist within the nucleus accumbens on the acquisition and expression of morphine - induced conditioned place preference in morphine - sensitized rats 显示文摘 | Azizi P Haghparast A Hassanpour - Ezatti M | 2009 | Behav Brain Res2009，197，1： | 1 |
| 19 | Review of recent research into cellulosic whiskers,their properties and their application in nanocomposite field显示文摘 | Azizi S Fannie A Alain D | | 0，，02： | 1 |
| 20 | Viability of calcium-alginate- microencapsulated probiotic bacteria in Iranian yo- gurt drink (Doogh) during refrigerated storage and under simulated gastrointestinal conditions显示文摘 | MORTAZAVIAN A M EHSANI M R AZIZI A | 2008 | Australian Journal of Dairy Technology2008，63，1： | 1 |
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