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| 1 | Dynamic and ultrastructural study of sphincter of Oddi in early-stage cholelithiasis in rabbits with hypercholesterolemia显示文摘AIM To study the relationship between pre-formation of gallstone and the kinetics and ultra-structure of sphincter of Oddi.METHODS Adult female rabbits were used anddivided into 3 groups,and fed with either normalor high cholesterol diet for four or eight weeks.Each group contained eight rabbits.Themanometry of sphincter of Oddi,biliarycineradiography,gallbladder volumemeasurement and ultrastructure observationunder electron microscope were performed.RESULTS In groups Ⅰ and Ⅱ,the basalpressure in low-pressure ampulla or highpressure zone of sphincter of Oddi waselevated,the amplitude of phasic contractionwas decreased and the volume of gallbladderwere increased,with a significant difference(P<0.01)from those of control.Gallstones werefound in group Ⅱ rabbits(7/8).Undercineradiography,low-pressure ampulla showeda spasmodic status without apparent peristalticcontraction.Under electron microscope,insidethe muscular cells of sphincter of Oddi,loosening of microfilament and swelling ofplasmosomes which congregated at the top wereobserved.The amount showed no obviouschange under nitric oxide synthase(NOS)stain.CONCLUSION Twisting of the microfilamentand disarrangement of kink macula densa insidethe muscular ceils suggested that the sphincterof Oddi was under spasmodic status.Theimpaired diastolic function caused andaggravated the stasis of cystic bile.Theswelling plasmosome could be one of theimportant factors in elevating the tonic pressureof sphincter of Oddi. | Wei JG Wang YC Du F Yu HJ | 2000 | World Journal of Gastroenterology2000，6，1： | 19 |
| 2 | 持续气道正压通气在预防阻塞性睡眠呼吸暂停患者心血管事件中的作用显示文摘阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)导致阵发性低氧血症,夜间交感神经系统激活,血压、氧化应激和炎症指标的升高以及高凝血症。较大的胸内负压波动也会给心脏和大血管施加机械应力。基于人群和睡眠诊所的队列研究显示,OSA与心脑血管事件,特别是脑卒中相关。 | McEvoy RD Antic NA Heeley E Luo Y Ou Q Zhang X Mediano O Chen R Drager LF Liu Z Chen G Du B McArdle N Mukherjee S Tripathi M Billot L Li Q Lorenzi-Filho G Barbe F Redline S Wang J Arima H Neal B White DP Grunstein RR Zhong N Anderson CS 练桂丽 叶鹏 | 2016 | 中华高血压杂志2016，24，11： | 4 |
| 3 | Improved 2-D Stability Margin Test for 2-D Discrete Systems | XIAO Yang\ DU Xiyu Institute of Information Science, Northern Northern Jiaotong University, Beijing, 100044 Rolf Unbehuen is with Lehrstuhl f Allgemeine und Theoretische Elektrotechnik UniversitT Erlangen Nrnberg, Cauerstr.7, 91058, Germany | 1998 | Systems Science and Systems Engineering1998，8，2： | 3 |
| 4 | Quality control measures for lowering the seroconversion rate of hemodialysis patients with hepatitis B or C virus显示文摘BACKGROUND: Hemodialysis (HD) patients are at high risk of infection by hepatitis B virus (HBV) or hepatitis C virus (HCV). The present study was designed to determine the impact of quality control measures on the prevention of transmission of blood-borne viruses. METHODS: A total of 6182 adult maintenance HD patients from all HD units in Zhejiang Province were recruited on January 1, 2007. The baseline demographic and clinical characteristics were recorded and all patients were followed up until death or survival at 4 years later. The Quality Control Standards of Hemodialysis were gradually implemented in HD units. The HBV or HCV seroconversion rates of the recruited patients were calculated and compared every year during the observation period. RESULTS: The prevalence of HBV was 8.3% at the beginning of the study, and 6.6% for HCV. With the implementation of the HD quality control measures, the HBV seroconversion rate tended to decrease year by year (χ 2 =6.620, P=0.085), and the HCV seroconversion rate decreased significantly (χ 2 =10.41, P=0.015). Compared with the data in 2007, the HBV seroconversion rate (χ 2 =4.204, P=0.040, relative risk ratio 0.393, 95% CI 0.156-0.991) and the HCV seroconversion rate (χ 2 =7.373, P=0.007, relative risk ratio 0.386, 95% CI 0.189-0.787) decreased significantly in 2010. CONCLUSION: Quality control measures for HD decreased the seroconversion rates of HBV or HCV in HD patients, showing that updated quality control measures reduce the risk for transmission of blood-borne viruses in the HD population. | Jing Yuan,Yi Yang, Fei Han, Ping Zhang, Xiao-Ying Du, Hua Jiang and Jiang-Hua Chen The Kidney Disease Center, First Affiliated Hospital, Zhejiang University School of Medicine (Yuan J, Yang Y, Han F, Zhang P, Du XY, Jiang H and Chen JH) and Hemodialysis Quality Control Center of Zhejiang Province (Yuan J, Zhang P, Du XY and Chen JH), Hangzhou 310003, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，3： | 2 |
| 5 | PHAPI, CAS and Hsp70 promote apoptosome formation by preventing Apaf- 1 aggregation and enhancing nucleotide exchange on Apaf- 1 显示文摘 | Kim HE Jiang X Du F | 2008 | Mol Cell2008，30，2： | 1 |
| 6 | Antioxidant capacity and the relationship with polyphenol and vitamin cin actinidia fruits显示文摘 | Du GR Li M J Ma F W | 2009 | Food Chemistry2009，，113： | 1 |
| 7 | Calcium-sensitive potassi- um channelopathy in human epilepsy and paroxysmal move- ment disorder显示文摘 | Du W Bautista J F Yang H | 2005 | Nat Genet2005，37，7： | 1 |
| 8 | Nanoparticle networks reduce the flammability of polymer nanocomposites 显示文摘 | Kashiwagi T Du F M Douglas J F | 2005 | Nature Materials2005，4，12： | 1 |
| 9 | Argonaute2 cleaves the anti - guide strand of siRNA during RISC activation 显示文摘 | Rand TA Petersen S Du F | 2005 | Cell2005，123，4： | 1 |
| 10 | Effects of ultrahigh pressure extraction conditions on yields and antioxidant activities of flavonoid from Laoying Tea显示文摘 | Ji H F Zhang L W Du A L | 2011 | International Journal of Food Engineering2011，7，5： | 1 |
| 11 | Controlled synthesis ofmesoporous Si02/Ni3Si205(0H)4 core-shell microsphereswith tunable chamber structures via a self -templatemethod显示文摘 | Guo Z Y Du F L Li G C | 2008 | Chem Commu2008，，： | 1 |
| 12 | Comparison of Batho, ETAR and Monte Carlo dose calculation method in CT based patient methods 显示文摘 | du Plessis F C Willemse C A L6tter M G | 2001 | Medical Physics2001，28，4： | 1 |
| 13 | Modified Postannealing of the Ge Condensation Process for Better-strained Si Material and Devices 显示文摘 | Liu X Y Ma X B Du X F | 2010 | Journal of Vacuum Science & Technology B : Microelectronics and Nanometer Structures2010，28，5： | 1 |
| 14 | Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia 显示文摘 | WANG P GUAN Y F DU H | 2012 | Autophagy2012，8，1： | 1 |
| 15 | Diversity of the predominant spoilage bacteria in water-boiled salted duck during storage显示文摘 | LIU F WANG D DU L | | 0，，05： | 1 |
| 16 | Physiological characteristics change of Aesculus chinensis seeds during nauural dehydration显示文摘 | Yu F Y Du Y Shen Y B | | 0，，02： | 1 |
| 17 | Genetic diversity of wild Au- ricularia auricula-judae revealed by ISSR analysis 显示文摘 | Du P Cui B K Zhang C F | 2013 | Bio- chemical Systematics and Ecology2013，48，： | 1 |
| 18 | Simultaneous determination of six active components in crude and processed Fructus Corni by high performance liquid chromatography显示文摘 | Du W F Cai H Wang M Y | 2008 | J Pharm Biomed Anal2008，48，1： | 1 |
| 19 | Myeloid-derived suppressor cells suppress antitmnor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer显示文摘 | Yu J Du W Yan F | 2013 | J Immunol2013，190，7： | 1 |
| 20 | Who Is Talking? An Ontology - based OpinionLeader Identification Framework forWord - of - mouth Marketingin Online Social Blogs 显示文摘 | Li F Du T C | 2011 | Decision Support Systems2011，，51： | 1 |
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