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| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | Comparison of high-resolution ultrasound and MR-enterography in patients with inflammatory bowel disease显示文摘AIM:To compare the results of high-resolution ultrasound(HR-US) and magnetic resonance enterography(MRE) examinations in patients with inflammatory bowel disease(IBD).METHODS:The reports of 250 consecutive cases with known IBD,who had an MRE and HR-US examination,were retrospectively analyzed.Using a patient-based approach we evaluated morphological disease features such as affected bowel wall,stenosis,abscess and fistula.The comparison between the two modalities was based on the hypothesis,that any pathological change described in any imaging modality was a true finding,as no further standard of reference was available for complete assessment.RESULTS:Two hundred and fifty examinations representing 207 different patients were evaluated.Both modalities assessed similar bowel wall changes in 65% of the examinations,with more US findings in 11% and more MRE findings in 15%.When the reports were analyzed with regard to 'bowel wall inflammation',US reported more findings in 2%,while MRE reported more findings in 53%.Stenoses were assessed to be identical in 8%,while US found more in 3% and MRE in 29%(P < 0.01).For abscess detection,US showed more findings in 2%(n = 4) while MRE detected more in 6%(n = 16).US detected more fistulas in 1%(n = 2),while MRE detected more in 13%(n = 32)(P < 0.001).The most common reason for no detected pathology by US was a difficult to assess anatomical region(lesser pelvis,n = 72).CONCLUSION:US can miss clinically relevant pathological changes in patients with IBD mostly due to difficulty in assessing certain anatomical regions. | Andreas G Schreyer Cynthia Menzel Chris Friedrich Florian Poschenrieder Lukas Egger Christian Dornia Gabriela Schill Lena M Dendl Doris Schacherer Christl Girlich Ernst-Michael Jung | 2011 | World Journal of Gastroenterology2011，17，8： | 7 |
| 3 | Surgery for Ductal Adenocarcinoma of the Pancreatic Head: Staging, Complications, and Survival after Regional versus Extended Lymphadenectomy显示文摘 | Doris Henne-Bruns Ilka Vogel Jutta Lüttges Günter Kl?ppel Bernd Kremer | 2000 | World Journal of Surgery2000，，5： | 2 |
| 4 | Myeloma renal disease: presentation and outcome 显示文摘 | Doris T Kathrine G Kieron D | 2006 | Nephron C|in Pract2006，10，1： | 1 |
| 5 | Geochemistry of the Rare Earth elements in spilites from the oceanic and continental crust显示文摘 | Albert Günter Herrmann Mark J. Potts Doris Knake | 1974 | Contributions to Mineralogy and Petrology1974，，1： | 1 |
| 6 | Full-spectrum cardiac surgery through a minimal incision:mini-sternotomy (lower half) technique显示文摘 | Doty D B Di Russo G B Dory J R | 1998 | Ann Thorac Surg1998，65，2： | 1 |
| 7 | Maffornation of cortial develop6 J ment in adult patients显示文摘 | Tinuper P Doris G Bisulli F | 2003 | Epileptic Disord2003，2，： | 1 |
| 8 | Sens Actuators B显示文摘 | Guidi V Cardinali G C Dori L | 1998 | 49(1-2):88-921998，49，12： | 1 |
| 9 | Interactive relations between universities and firms: Empirical evidence for Austria 显示文摘 | Doris S Andras S Helmut G | 2001 | Journal of Technology Transfer2001，26，3： | 1 |
| 10 | The effect of three different calcium phosphate implant coatings on bone deposition and coating resorption:a long-term histological study in sheep显示文摘 | Christian S Doris M Walter G | 2005 | Clinicai Oral Implants Research2005，16，： | 1 |
| 11 | The Development of Dtaxonomy of Career Competencies for Professional Women 显示文摘 | Hackett G Betz N E Dory M S | 1985 | Sex Roles1985，，12： | 1 |
| 12 | Surgery for Ductal Adenocarcinoma of the Pancreatic Head: Staging, Complications, and Survival after Regional versus Extended Lymphadenectomy显示文摘 | Doris Henne-Bruns Ilka Vogel Jutta Lüttges Günter Kl?ppel Bernd Kremer | 2000 | World Journal of Surgery2000，，5： | 1 |
| 13 | Ectopic Expression of Hu- man telomerase RNA component results in increased telomerase activity and elongated telomeres in bovine blastocysts 显示文摘 | Wiebke G Wilfried B Doris H | 2012 | Biol Reprod2012，10，： | 1 |
| 14 | Ligand accessibility as means to control cell response to bioactive bilayer membranes显示文摘 | Dori Y Havazelet B P Satija S K Fields G B | 2000 | J Biorned Mater Res2000，50，1： | 1 |
| 15 | Changes in the initial slope of the QRS in ischemic patients and normal subjects undergoing scintigraphy with dipyridamole 显示文摘 | Dori G Gershinsky M Ben-Haim S | 2010 | Comput Biol Med2010，40，1112： | 1 |
| 16 | Exercise stress testing,myocardial perfusion imaging and stress echocardiography for detecting restenosis after successful percutaneous transluminal coronary angioplasty:a review of performance 显示文摘 | Dori G Denekamp Y Fishman S Bitterman H | 2003 | J Intern Med2003，253，3： | 1 |
| 17 | Exercise stress testing, myocardial perfusion imaging and stress echocardiography for detecting restenosis after successful percutaneous transluminal coronary angioplasty: a review of performance显示文摘 | DORI G DENEKAMP Y FISHMAN S | 2003 | J Intern Med2003，253，： | 1 |
| 18 | Outcome of Liver Transplantation Based on Donor Graft Quality and Recipient Status显示文摘 | B. Nemes F. Gelley G. Zádori L. Piros J. Perneczky L. Kóbori I. Fehérvári D. G?r?g | 2010 | Transplantation Proceedings2010，，6： | 1 |
| 19 | Exercise stress testing, myocardial perfusion imaging and stress echocardiography for detecting restenosis after successful percutaneous transluminal coronary angioplasty : a review of performance 显示文摘 | Dori G Denekamp Y Fishman S | 2003 | J Intern Med2003，253，3： | 1 |
| 20 | ECG variability contour-a reference for evaluating the significance of amplitude ECG changes in twostates显示文摘 | DORI G BITTERMAN H | 2008 | Physiological measurement2008，29，： | 1 |
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