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| 1 | Usefulness of duodenal biopsy during routine upper gastrointestinal endoscopy for diagnosis of celiac disease显示文摘瞄准:在一张成年西班牙的人口在平淡的上面的胃肠的内视镜检查法期间在十二指肠的活体检视性能描述趋势,并且在临床的实践为乳糜泻的诊断分析它的值。方法:在当承担上面的胃肠的内视镜检查法时,执行的十二指肠的活体检视的 15 年趋势(1990 ~ 2004 ) 被学习。我们与贫血症或长期的腹泻在全面的组,并且在亚群分析了乳糜泻的流行。结果:十二指肠的活体检视在 13 678 上面的胃肠的内视镜检查法(7.6%) 中的 1033 个被执行;这的使用的增加在学习时期上被观察(1.9% 在 1990-1994, 5% 在 1995-1999 并且 12.8% 在 2000-2004 ) 。乳糜泻在 22 个病人(2.2%) 被诊断,这比在男人在女人是更经常的(3% 和 1% 分别地) 。十四从 514 (2.7%) 有贫血症的病人, 12 从 141 (8.5%) 与长期的腹泻并且 8 (19%) 从 42,与贫血症,正长期的腹泻有乳糜泻。一个古典临床的演讲在 55% 盒子中被观察, 23% 病人联系了疱疹样皮炎和 64% 介绍贫血症;9% 被家庭屏蔽诊断并且 5% 由秘密成员基因 hypertransaminasaemia。结论:在成年人在平淡的上面的胃肠的内视镜检查法期间承担的十二指肠的活体检视,逐渐地被合并了到临床的实践,并且是为在象有贫血症或长期的腹泻的那些那样的高风险组的乳糜泻的诊断的一个有用工具。 | S Riestra F Domínguez E Fernández-Ruiz E García-Riesco R Nieto E Fernández L Rodrigo | 2006 | World Journal of Gastroenterology2006，12，31： | 4 |
| 2 | Recombinant streptokinase vs hydrocortisone suppositories in acute hemorrhoids:A randomized controlled trial显示文摘AIM: To compare the efficacy and safety of recombinant streptokinase(rSK) vs hydrocortisone acetate-based suppositories in acute hemorrhoidal disease.METHODS: A multicenter(11 sites), randomized(1:1:1), open, controlled trial with parallel groups was performed. All participating patients gave their written,informed consent. After inclusion, patients with acute symptoms of hemorrhoids were centrally randomized to receive, as outpatients, by the rectal route, suppositories of rSK 200000 IU of one unit every 8 h(first 3 units)and afterwards every 12 h until 8 administrations were completed(schedule A), one unit every 8 h until 6 units were completed(schedule B), or 25 mg hydrocortisone acetate once every 8 h up to a maximum of 24 administrations. Evaluations were performed at 3, 5,and 10 d post-inclusion. The main end-point was the 5thday response(disappearance of pain and bleeding, and≥ 70% reduction of the lesion size). Time to response and need for thrombectomy were secondary efficacy variables. Adverse events were also evaluated.RESULTS: Groups were homogeneous with regards to demographic and baseline characteristics. Fifth day complete response rates were 156/170(91.8%; 95%CI:87.3-96.2), 155/170(91.2%; 95%CI: 86.6%-95.7%),and 46/170(27.1%; 95%CI: 20.1%-34.0%) with rSK(schedule A and B) and hydrocortisone acetate suppositories, respectively. These 64.6% and 63.9%differences(95%CI: 56.7%-72.2% and 55.7%-72.0%)were highly significant(P < 0.001). This advantage was detected since the early 3rd day evaluation(68.8% and64.1% vs 7.1% for the rSK and active control groups,respectively; P < 0.001) and was maintained even at the late 10 th day assessment(97.1% and 93.5% vs67.1% for rSK and hydrocortisone acetate, respectively;P < 0.001). Time to response was 3 d(95%CI: 2.9-3.1)for both rSK groups and 10 d(95%CI: 9.3-10.7) in the hydrocortisone acetate group. This difference was highly significant(P < 0.001). All subgroup stratified analyses(with or without thrombosis and hemorrhoid classification) showed a statistically significant advantage for the rSK groups. Thrombectomy was necessary in4/251 and 14/133 patients with baseline thrombosis in the rSK and hydrocortisone acetate groups, respectively(P < 0.001). There were no adverse events attributable to the experimental treatment.CONCLUSION: rSK suppositories showed a significant advantage over a widely-used over-the-counter hydrocortisone acetate preparation for the treatment of acute hemorrhoidal illness, as well as having an adequate safety profile. | Francisco Hernández-Bernal Georgina Castellanos-Sierra Carmen M Valenzuela-Silva Karem M Catasús-Alvarez Osmany Martínez-Serrano Odalys C Lazo-Diago Cimara H Bermúdez-Badell José R Causa-García Juan E Domínguez-Suárez Pedro A López-Saura 无 | 2015 | World Journal of Gastroenterology2015，21，23： | 2 |
| 3 | Heroin-related noncardiogenie pulmonary edema:a case series显示文摘 | Dom E | 2001 | Chest2001，120，5： | 1 |
| 4 | Prophylactic antibiotics for mesh inguinal hernioplasty:a meta-analysis显示文摘 | Sanabria A Domínguez LC Valdivieso E | | 0，，03： | 1 |
| 5 | Effect of porins and plasmid-mediated AmpC β-lactamases on the efficacy of β-lactams in rat pneumonia caused by Klebsiella pneumoniae显示文摘 | Padilla E Alonso D Doménech-Sánchez A | 2006 | Antimicrob Agents Chemother2006，50，： | 1 |
| 6 | Klebsiella pneu-moniae AcrAB efflux pump contributes to antimicrobial resistance and virulence显示文摘 | Padilla E Llobet E Doménech-Sánchez A | 2010 | Antimicrob Agents Chemother2010，54，1： | 1 |
| 7 | Mining the Web's link structure computer显示文摘 | CBAKRA BARTIS DOM B E GIBSON D | | 0，，08： | 1 |
| 8 | Retrograde nailing offemur:surgical technique with tibial traction显示文摘 | Garcia Crespo R Moro E Dom inguezI | | 0，，： | 1 |
| 9 | Mining the Web' s link structure显示文摘 | Chakrabarti S Dom B E Kumar S R | 1999 | Computer1999，32，8： | 1 |
| 10 | Capital Adjustment Patterns in Manufacturing Plants 显示文摘 | Mark E Doms Timothy Dunne | 1998 | Review of Economic Dynamics1998，，2： | 1 |
| 11 | Association of Pseudomonas anguilliseptica infection with winter disease' in sea bream,Sparus aurata L显示文摘 | DOM(E)NECH A FERN(A)NDEZ-GARAYZ(A)BAL J F GARCíA J A | 1999 | J Fish Dis1999，22，： | 1 |
| 12 | Alkali treatment of viscose cellulosic fibers from eucalyptus wood:Structural,morphological,and thermal analysis显示文摘 | Rojo E Alonso M Domínguez J C | 2013 | Journal of Applied Polymer Science2013，130，3： | 1 |
| 13 | Osteoporosis and diabetes显示文摘 | Dom inguez LJ Muratore M Quarta E | | 0，，04： | 1 |
| 14 | A new classification for HIV-I显示文摘 | Berger E A Doms R W Fenyo E M | 1998 | Nature1998，391，： | 1 |
| 15 | Mining the Web's Link Structure显示文摘 | Dom B E Kumar S R etal | 1999 | Computer1999，32，8： | 1 |
| 16 | Increased numbers of myeloid and lymphoid IL-10 producing cells in spleen of pigs with naturally occurring postweaning multisystemic wasting syndrome显示文摘 | CRISCI E BALLESTER M DOMíINGUEZ J | | 0，，3： | 1 |
| 17 | Baseline toxic mixtures of non-toxic chemicals: 'Solubility addition' increases exposure for solid hydrophobic chemicals 显示文摘 | Smith K E C Schmicdt S N Dom N | 2013 | Environmental Science & Technology2013，47，4： | 1 |
| 18 | Host cell-catalyzed Spalmitoylation mediates Golgi targeting of the legionella ubiquitin ligase Gob X显示文摘 | LIN Y H DOMS A G CHENG E | 2015 | J Biol Chem2015，290，25： | 1 |
| 19 | Production of antioxidants by non-isothermal autohydrolysis of lignocellulosic wastes显示文摘 | Conde E Moure A Domínguez H | 2011 | LWT-Food Science and Technology2011，44，2： | 1 |
| 20 | Barriers Perceived by Teachers at Work, Coping Strategies, Self-efficacy and Burnout 显示文摘 | Betoret Femando Dom e nech Artiga Amparo G 6 mez | 2010 | The Spanish Journal of Psychology2010，13，2： | 1 |
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