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| 1 | Management of pregnancy in Crigler Najjar syndrome type 2显示文摘Crigler Najjar syndrome is associated with indirect hyperbilirubinemia due to a deficiency of enzyme Uridine Di Phospho Glucoronosyl Transferase(UDPGT).Presented here is a case of a female in the first trimester of pregnancy,who was diagnosed to have type 2 Crigler Najjar syndrome.We also discuss the management of this rare disease especially in pregnancy.Unconjugated bilirubin can cross the placental barrier causing neuro-logical damage in the newborn.Patient was carefully monitored during pregnancy and treatment with pheno-barbitone in low doses was adjusted such that the serum bilirubin levels were below 10 mg/d L.Crigler Najjar syndrome being rare needs to be diagnosed early in pregnancy to avoid adverse fetal outcomes.Phenobarbitone being an inducer of enzyme UDPGT is used as the first line of treatment and is not teratogenic in the low doses used.Treatment protocol followed was on the basis of previous reported cases and successful perinatal outcome was achieved. | Alisha Nitin Chaubal Ruchir Patel Dhaval Choksi Kaivan Shah Meghraj Ingle Prabha Sawant | 2016 | World Journal of Hepatology2016，8，11： | 4 |
| 2 | Study of locust bean gum reinforced cyst-chitosan and oxidized dextran based semi-IPN cryogel dressing for hemostatic application显示文摘Severe blood loss due to traumatic injuries remains one of the leading causes of death in emergency settings.Chitosan continues to be the candidate material for hemostatic applications due to its inherent hemostatic properties.However,available chitosan-based dressings have been reported to have an acidic odor at the wound site due to the incorporation of acid based solvents for their fabrication and deformation under compression owing to low mechanical strength limiting its usability.In the present study semi-IPN cryogel was fabricated via Schiff's base cross-linking between the polyaldehyde groups of oxidized dextran and thiolated chitosan in presence of locust bean gum(LBG)known for its hydrophilicity.Polymerization at12C yielded macroporous semi-IPN cryogels with an average pore size of 124.57±20.31 mm and 85.46%porosity.The hydrophobicity index of LBG reinforced semi-IPN cryogel was reduced 2.42 times whereas the swelling ratio was increased by 156.08%compare to control cryogel.The increased hydrophilicity and swelling ratio inflated the compressive modulus from 28.1 kPa to 33.85 for LBG reinforced semi-IPN cryogel.The structural stability and constant degradation medium pH were also recorded over a period of 12 weeks.The cryogels demonstrated lower adsorption affinity towards BSA.The cytotoxicity assays(direct,indirect)with 3T3-L1 fibroblast cells confirmed the cytocompatibility of the cryogels.The hemolysis assay showed<5%hemolysis confirming blood compatibility of the fabricated cryogel,while whole blood clotting and platelet adhesion assays confirmed the hemostatic potential of semi-IPN cryogel. | Lalit Kumar Meena Pavani Raval Dhaval Kedaria Rajesh Vasita | 2018 | Bioactive Materials2018，3，3： | 4 |
| 3 | Biomimetic polycaprolactone-chitosan nanofibrous substrate influenced cell cycle and ECM secretion affect cellular uptake of nanoclusters显示文摘Biomimetic cell culture substrates are developed as an alternative to the conventional substrates.They provide necessary biochemical and biophysical cues to the cells from their surrounding environment for their optimal growth,behaviour and physiology.Changes in physiology of cells growing on biomimetic substrate can essentially affect results of in vitro biological experiments such as drug cytotoxicity,nanoparticle internalization or signalling pathways.As majority of ECM proteins are fibrous in nature,nanofibrous scaffolds have more biomimicking properties.Therefore,in this study,we developed ECM mimicking polycaprolactone-chitosan nanofiber substrate and evaluated its effect on cell morphology,proliferation,cell cycle and ECM production.Further,cellular uptake of BSA-AuNCs has been assessed on conventional and biomimetic substrate in order to demonstrate the effect of these events on cellular properties.It was observed that the cells that were grown for 15 days on the nanofibers,had majority of cells in the proliferative phase of cell cycle compared to TCPS.Moreover,these cells showed extensive collagen and fibronectin production.Due to these conditions C3H10T1/2 cells displayed higher cell internalization of BSA-AuNCs.Overall,this study indicates that the nano-topographical and biochemical environment could alter the cell proliferative behaviour and ECM production,which affects the cell internalization of BSA-AuNCs.Also,PCL-chitosan nanofibrous substrate could be a better alternative to TCPS for cell culture studies. | Dhwani Jhala Hilal Rather Dhaval Kedaria Juhi Shah Sanjay Singh Rajesh Vasita | 2019 | Bioactive Materials2019，4，1： | 4 |
| 4 | 曲霞可视喉镜在老年患者困难气道中的应用探讨显示文摘目的分析视曲霞斯美特视喉镜用于老年患者的困难气道的临床处理,在气管插管时的可行性与安全性进行探讨。方法从2015年9月至2016年6月手术患者中选择80例老年困难气道患者作为研究对象,在全身麻醉后随机分为两组,每组各40例,其中Q组使用曲霞斯美特可视喉镜插管,M组使用Macintosh直接喉镜进行插管。插管操作在两组患者中均由同一位主治医师以上职称、工作经验较为丰富的麻醉科医师完成.记录并分析诱导前、诱导时以及插管时、插管后心率、血压和血氧的变化情况,对比分析气管插管时间、成功率、并发症等情况。结果 Q组的插管的成功率明显优于M组,咽喉部黏膜没有明显的损害,血压、心率、血氧饱和度更为稳定。结论在老年患者的困难气道的处理中,曲霞斯美特可视喉镜比Macintosh喉镜更优势,操作过程中可清楚看见咽喉和气道的解剖结构,减轻了对咽喉部位的刺激和气管插管时的心血管反应。 | 张福清 叶根华 Siddique Dhaval | 2017 | 中国医药指南2017，15，24： | 3 |
| 5 | Prognostic impact of atrial fibrillation on clinical outcomes of acute coronary syndromes,heart failure and chronic kidney disease显示文摘Atrial fibrillation(AF) is the most common type of sustained arrhythmia,which is now on course to reach epidemic proportions in the elderly population. AF is a commonly encountered comorbidity in patients with cardiac and major non-cardiac diseases. Morbidity and mortality associated with AF makes it a major healthcare burden. The objective of our article is to determine the prognostic impact of AF on acute coronary syndromes,heart failure and chronic kidney disease. Multiple studies have been conducted to determine if AF has an independent role in the overall mortality of such patients. Our review suggests that AF has an independent adverse prognostic impact on the clinical outcomes of acute coronary syndromes,heart failure and chronic kidney disease. | Nileshkumar J Patel Aashay Patel Kanishk Agnihotri Dhaval Pau Samir Patel Badal Thakkar Nikhil Nalluri Deepak Asti Ritesh Kanotra Sabeeda Kadavath Shilpkumar Arora Nilay Patel Achint Patel Azfar Sheikh Neil Patel Apurva O Badheka Abhishek Deshmukh Hakan Paydak Juan Viles-Gonzalez | 2015 | World Journal of Cardiology2015，7，7： | 2 |
| 6 | 两个热带树种(柚木和印度实竹)叶面积指数估测异速生长方程(英文)显示文摘通过破坏性抽样、相片网格法和落叶采受器法,获得了印度Shoolpaneshwar野生动物禁猎区内生长的柚木和印度实竹叶面积指数。建立了一个异速生长方程来决定两个树种的叶面积指数。结果表明,异速生长方程获得的叶面积指数与破坏性抽样、相片网格法和落叶采受器法评估得到的指数值相近;2种测定方式下,柚木的均方根误差分别是0.90和1.15,印度实竹的均方根误差分别为0.38和0.46。估计的和计算获得的叶面积指数值匹配性较好,说明用建立的方程计算得到的2个树种叶面积指数的准确性较好。总之,冠幅伸展是一个估计树木叶面积较好的且敏感的参数。本文所提出的方程可以用作估计热带柚木和印度实竹叶面积指数。图4表1参22。 | Dhaval Vyas Nirav mehta J.Dina-karan N.S.R.Krishnayya | 2010 | Journal of Forestry Research2010，21，2： | 2 |
| 7 | 电源电子技术在降低能耗中的角色显示文摘全世界对能源消耗的关注日渐增加。作为减少能源消耗的两种方式,能源节省需要个人的自觉性加社会决策,而能效提升就纯粹是一个技术问题。美国使用的电能中的3%在电子电源转换过程中耗散为热量。因此电源电子产业,包括半导体公司、电源公司和终端产品制造商正在努力使这些损耗减少一半。他们所采用的方式就是提升大批量消费电子产品中的电源转换效率并降低待机能耗。 | Chuck Mullett Dhaval Dalal | 2008 | 今日电子2008，，4： | 2 |
| 8 | Beyond Megalopolis:Exploring America's New 'Megapllitan 'Geography显示文摘 | R E Lang D Dhavale | | 0，，01： | 1 |
| 9 | Online tuning of a steady state crude distillation unit model for real time applications显示文摘 | Dhaval J Dave Murtuza Z Dabhiya Satyadev S V K | 2003 | Journal of Process Control2003，13，3： | 1 |
| 10 | Graphene-polymer nanocomposites for structural and functional applications显示文摘 | Kesong Hu Dhaval D. Kulkarni Ikjun Choi Vladimir V. Tsukruk | 2014 | Progress in Polymer Science2014，，： | 1 |
| 11 | Cross-Polarization Cancellation in an Offset Parabolic Reflector Antenna Using a Corrugated Matched Feed显示文摘 | SHARMA S B PUJARA Dhaval CHAKRABARTY S B | 2009 | IEEE Antennas and Wireless Prop- agation Letters2009，，8： | 1 |
| 12 | Synthesis, characterization and thermolysis studies on new derivatives of 2,4,5-trinitroimidazoles: Potential insensitive high energy materials显示文摘 | H.S. Jadhav M.B. Talawar R. Sivabalan D.D. Dhavale S.N. Asthana V.N. Krishnamurthy | 2006 | Journal of Hazardous Materials2006，，1： | 1 |
| 13 | Managing platform architectures and manufacturing processes for m on-assembled rod ucts显示文摘 | MARC H M DHAVAL D | 2002 | The Journal of Product Innovation Management2002，，19： | 1 |
| 14 | Responding to Major Threats to Self-esteem: A Preliminary, Narrative Study of Ego-shock 显示文摘 | Campbell W K Baumeister R F Dhavale D | 2003 | Journal of Social and Clinical Psychology2003，22，1： | 1 |
| 15 | Significance of alterations in plasma lipid profile levels in breast cancer显示文摘 | Franky Dhaval Shah Shilin Nandubhai Shukla Pankaj Manubhai Shah | 2008 | Integr Cancer Ther2008，7，1： | 1 |
| 16 | Security versus status? a first look at the census's gated community data显示文摘 | SANCHEZ T W LANG R E DHAVALE D M | 2005 | Journal of Planning Education and Research2005，24，3： | 1 |
| 17 | Managing platform architectures and manufacturing processes for nonassembled products显示文摘 | Marc H. Meyer Dhaval Dalal | 2002 | The Journal of Product Innovation Management2002，，4： | 1 |
| 18 | Improvement in shelf - life and safety of perishable foods by plant essential oils and smoke antimicrobials 显示文摘 | Richard A Holley Dhaval Patel | 2005 | Food Microbiology2005，22，： | 1 |
| 19 | Activated alumina-promoted reaction of aldehydes with ethyl diazoacetate: a simple route to β-oxo esters 显示文摘 | DHAVALE D D PATIL P N MALl R S | 1994 | J Chem Res1994，1994，4： | 1 |
| 20 | Responding to Major Threats to Self-esteem: A Preliminary,Narrative Study of ego-shock 显示文摘 | Baumeister R F Dhavale D Tice D M | 2003 | Journal of Social and Clinical Psychology2003，22，1： | 1 |
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