|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Immunohistochemical assessment of angiogenesis in hepatocellular carcinoma and surrounding cirrhotic liver tissues显示文摘AIM: To investigate whether vascular endothelial growth factor (VEGF) was over-expressed in hepatocellular carcinoma (HCC) or in surrounding cirrhotic liver tissues.METHODS: Immunohistochemistry was performed to investigate the expression of VEGF proteins in HCC tissues from 105 consecutive patients undergoing curative resection for HCC. The immunostaining results and related clinicopathologic materials were analyzed with statistical methods. Kaplan-Meier method was used to calculate survival curves, and Log-rank test was performed to compare differences in survival rates of the patients with positive HCC staining and negative VEGF.RESULTS: VEGF-positive expression was found in 72 of105 HCC patients (68.6%). Capsular infiltration (P= 0.005),vascular invasion (P = 0.035) and intrahepatic metastasis(P=0.008) were observed more frequently in patients with VEGF-positive expression than in those with VEGFnegative expression. Kaplan-Meier curves showed that VEGF-positive expression was associated with a shorter overall survival (P = 0.014). VEGF-positive expression was found in 47 of tissues 68 HCC (69.1%), and VEGF-positive expression was found in 54 of 68 surrounding cirrhotic liver tissues (79.4%). VEGF-positive expression was significantly higher in surrounding cirrhotic liver tissues than in HCC (P= 0.017).CONCLUSION: VEGF may play an important role in the angiogenesis and prognosis of HCC, as well as in the angiogenesis of liver cirrhosis. | GeertuDeli Can-HaoJin RongMu SongYang YueLiang DeChen MasatoshiMakuuchi | 2005 | World Journal of Gastroenterology2005，11，7： | 19 |
| 2 | 催化剂活性组成对纳米碳纤维产率和微结构的影响显示文摘采用沉积 沉淀法制备了活性组成可控的镍铁系列催化剂 ,以CO/H2 为碳源 ,在 6 0 0℃下进行了纳米碳纤维的催化生长 ,考察了催化剂活性组成变化对纳米碳纤维产率和微结构的影响 .结果表明 ,镍铁系列催化剂具有较好的催化活性 ,在反应36h内没有失活 ,催化剂中Fe的存在有利于提高纳米碳纤维的产率 .表征结果表明 ,纳米碳纤维的直径分布较为均匀 ,在 2 0~ 5 0nm之间 ,比表面积为 130~ 2 0 0m2 / g;纳米碳纤维中石墨层与轴之间夹角随催化剂中Fe含量的增大而增大 ;TPO结果表明 ,Fe的存在提高了纳米碳纤维的石墨化程度 .结合纳米碳纤维的生长机理 ,认为活性组成的变化影响了CO与催化剂表面的反应和碳在金属中的扩散 ,进而影响纳米碳纤维的产率和微结构 . | 赵铁均 朱贻安 李平 DeChen 戴迎春 袁渭康 AndersHolmen | 2004 | 催化学报2004，25，10： | 12 |
| 3 | The MOOC/SPOC Based'1+M+N'Multi-University Collaborative Teaching and Learning Mode:Practice and Experience显示文摘Since 2012, the MOOCs, the massive open online courses, have brought big influences on the higher education in the world. How to use MOOCs to help universities rather than bother them to improve their education level and quality becomes an important issue. In China, many universities have explored the new modes and approaches for MOOC/SPOC-based teaching and learning. Especially, the China MOOC Association on Computing Education(CMOOC association), established in 2014, has done a set of successful practice and achieved fruitful experiences on MOOC courses development and computer education reform. Based on the practical experiences, a MOOC/SPOC based '1+M+N' multi-university collaborative teaching and learning mode is presented, which is adapted to the real situation of Chinese university education. In the paper, the practices and experiences of CMOOC association are introduced, the MOOC/SPOC based '1+M+N' multi-university collaborative teaching and learning mode and its approaches are described. Finally, the suggestions for MOOCs development and applications are also presented. | Xiaofei Xu Dechen Zhan Ce Zhang Dianhui Chu Weihua Guo | 2018 | 计算机教育2018，，12： | 11 |
| 4 | Typical earthquake-induced soft-sediment deformation structures in the Mesoproterozoic Wumishan Formation, Yongding River Valley, Beijing, China and interpreted earthquake frequency | Su Dechen Sun Aiping | 2012 | Journal of Palaeogeography2012，1，1： | 10 |
| 5 | Effect of removing silica in rice husk for the preparation of activated carbon for supercapacitor applications显示文摘Renewable biomass-derived activated carbons have attracted attentions for supercapacitor applications. Rice husk is a kind of abundant biomass, which has been studied for the preparation of hierarchical activated carbons. Rice husk is rich in silica. Silica in rice husk affects the formation of pore structure in the KOH activation process, which further affects the electrochemical performance of the resultant activated carbon for supercapacitors. In this paper, the effects of silica in rice husk on the activation process were investigated. When the silica in rice husk is not removed, KOH preferentially reacts with silica to produce silicate, which hinders the formation and enlargement of mesopores;the obtained activated carbon exhibits high microporous ratio, high specific area (up to 3263 m^2/g), high specific capacitance (315 F/g at 0.5 A/g), but poor rate capability (51.7%capacitance retention with increasing the current density from 0.5 A/g to 20 A/g). When the silica in rice husk is removed, the pores produced by the removal of silica are etched to mesopores in activation process;the obtained activated carbon exhibits high mesoporous ratio, relative high specific surface area of 2804 m2/g and relative high capacitance of 278 F/g at 0.5 A/g with excellent rate capability (76.6%capacitance retention with increasing the current density from 0.5 A/g to 20 A/g). | Dechen Liu Wenli Zhang Weimin Huang | 2019 | Chinese Chemical Letters2019，30，6： | 7 |
| 6 | Deformed stromatolites in marbles of the Mesoproterozoic Wumishan Formation as evidence for synsedimentary seismic activity显示文摘The Mesoproterozoic Wumishan Formation consists mainly of dolomites that represent diagenetically transformed limestones deposited in a shallow peritidal environment.Although the environment was tectonically stable,the study area in the Changping District(north of the Beijing area) was affected by synsedimentary earthquakes.Later,the dolomites in the study area were intruded by a granite.This resulted in contact metamorphism of the dolomites,changing them in a halo around the intrusion into marble.This marble,which is exposed near Taoyukou Village,shows some levels with well-developed stromatolites.The stromatolites contain structures that point at deformation when the stromatolites had not yet been lithified,and thus represent soft-sediment deformation structures.The stromatolites apparently built up during a time-span when repeated deformational processes affected the still unlithified sediment,from the sedimentary surface down to maximally a few decimeters.The deformed stromatolites thus represent seismites,which feature is exceptionally rarely recognizable in marble. | A.J.(Tom) van Loon Su Dechen | 2013 | Journal of Palaeogeography2013，2，4： | 7 |
| 7 | Highly biocompatible BSA-MnO_2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy显示文摘More recently, the biomedical applications of MnO_2 in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However,research on a near infrared(NIR) photothermal response of MnO_2 was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin(BSA)-reduced and stabilized MnO_2 nanoparticles(BSA-MnO_2 NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO_2 NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent. | Yuzhen Wang Yujun Song Guixian Zhu Dechen Zhang Xuewu Liu | 2018 | Chinese Chemical Letters2018，29，11： | 5 |
| 8 | Label-free fiber nanograting sensor for real-time in situ early monitoring of cellular apoptosis显示文摘The achievement of functional nanomodules for subcellular label-free measurement has long been pursued in order to fully understand cellular functions.Here,a compact label-free nanosensor based on a fiber taper and zinc oxide nanogratings is designed and applied for the early monitoring of apoptosis in individual living cells.Because of its nanoscale dimensions,mechanical flexibility,and minimal cytotoxicity to cells,the sensing module can be loaded in cells for long term in situ tracking with high sensitivity.A gradual increase in the nuclear refractive index during the apoptosis process is observed,revealing the increase in molecular density and the decrease in cell volume.The strategy used in our study not only contributes to the understanding of internal environmental variations during cellular apoptosis but also provides a new platform for nonfluorescent fiber devices for investigation of cellular events and understanding fundamental cell biochemical engineering. | Danran Li Nina Wang Tianyang Zhang Guangxing Wu Yifeng Xiong Qianqian Du Yunfei Tian Weiwei Zhao Jiandong Ye Shulin Gu Yanqing Lu Dechen Jiang Fei Xu | 2022 | Advanced Photonics2022，4，1： | 5 |
| 9 | KOH Direct Activation for Preparing Activated Carbon Fiber from Polyacrylonitrile-based Pre-oxidized Fiber显示文摘 | GAO Lili LU Haiyan LIN Haibo SUN Xiuyun XU Jianling LIU Dechen LI Yang | 2014 | Chemical Research in Chinese Universities2014，30，3： | 4 |
| 10 | Nanoelectrochemical architectures for high-spatial-resolution single cell analysis显示文摘The analysis of single cells instead of cell populations is important for characterizing cellular heterogeneity and elucidating the cellular signalling pathways. Nanoelectrodes have emerged as an increasingly important tool for biomolecule analyses at the single-cell level with high spatial or temporal resolution. Various electrochemical methods, such as amperometry and scanning electrochemical microscopy(SECM), have been applied. Research to date has focused on the development of new nanoelectrochemical architectures, such as arrays, to achieve higher spatial resolution and faster analysis rates for single-cell analysis. In this review, the fabrication of these new nanoelectrochemical architectures and their applications in high spatial resolution single-cell analyses are discussed. The recent progress of Chinese researchers is highlighted. | Junyu Zhou Dechen Jiang Hong-Yuan Chen | 2017 | Science China Chemistry2017，60，10： | 3 |
| 11 | Enhancing interaction performance of soft pneumatic-networks grippers by skeleton topology optimization显示文摘The inherent compliance of soft materials imbues robots,generally referred to as soft robots,with particular advantages in producing adaptive and safe interactions.However,the mainstream design paradigms of soft robots have been focused on pursuing large free motions only,usually at the expense of greatly decreased stiffness,leading to limited capability of withstanding external loads in interactive scenarios.There is a pressing need to incorporate the interaction specifications at the design stage to embody soft robots with not only proper deformability but equally importantly,considerable stiffness to perform complex tasks in practical applications.Here,inspired by the dexterity of human hands,we propose a computational design framework for soft grippers with a focus on improving their interaction performance in power grasping or precision grasping mode.The design paradigm rests on attaching a relatively stiffer skeleton layer to the parametric pneumatic networks based actuator which is widely used due to the geometric advantage,and the skeleton layout is designed for customized interaction conditions by a level set based topology optimization approach.As expected,the optimized skeleton layouts exhibit specified structural features highly relevant to the predefined concentrated loads for precision grip or distributed loads for power grip,which physically implies the compromise between deformability and stiffness.Since the interaction forces are difficult to measure in situ,we devise power and precision grasping scenarios and evaluate the critical actuation pressure of the object’s falling instead.The experiments qualitatively demonstrate the superiority of each specified design.This work represents an initial step toward the rational design for interaction in soft robots. | CHEN ShiTong WANG YuSheng LI DeChen CHEN FeiFei ZHU XiangYang | 2021 | Science China(Technological Sciences)2021，64，12： | 2 |
| 12 | Open Shape Model Based on Absolute Frame in Three-dimensional Space显示文摘 | Liu Yongshan Gao Shiwei Wang Dechen | | 0，，03： | 1 |
| 13 | Th1/Th2 immune response显示文摘 | Dechene L | 2002 | J Allergy Clin Immunol2002，110，3： | 1 |
| 14 | Genesis of an unusual clastic dike in an uncommon braided river deposit显示文摘A clastic dike containing unusually large clasts occurs in the Quaternary deposits that unconformably cover the Mesoproterozoic sediments in the Fangshan District,Beijing area,China.The material into which the dike intruded is also uncommon because it consists mainly of loess-type silts that were deposited by braided rivers.The intrusion of the dike is explained as the result of the expulsion of pore water into the coarse,gravel-containing layers of a braided river system.The large size of the clasts in the dike is explained by an exceptionally strong upwards directed flow which owed its high energy to a high hydrostatic pressure that had been built up because pore water could not gradually seep through the impermeable silt-sized material during ongoing burial.This uncommon dike is compared with a second example,in similar Quaternary sediments covering the Mesozoic rocks in the Huairou District. | Su Dechen A.J.(Tom) van Loon Sun Aiping | 2013 | Journal of Palaeogeography2013，2，2： | 1 |
| 15 | A Specification-based Approach for Retrieval of Reusable Business Component forSoftware Reuse显示文摘 | Meng Fanchao Zhan Dechen Xu Xiaofei | 2006 | International Journal of Computer Science2006，1，4： | 1 |
| 16 | High Prevalence of Mental Disorders and Emotional Distress in Patients with Chronic Spontaneous Urticaria显示文摘 | Staubach P Dechene M Metz M | 2011 | Acta Dermato-Venereo- logica2011，91，5： | 1 |
| 17 | Correlates of vaginal colonization with group B among pregnant women 显示文摘 | Dechen TC Sunlit K Ranabir P | 2010 | J Glob Infect Dis2010，2，3： | 1 |
| 18 | Research on logistics domain-oriented cloud resource management model and architecture显示文摘To address the challenges posed by resource shortage or surplus to enterprises productivity,Internet platforms have been widely used,which can balance shortage and surplus in broader environments. However,the existing resource management models lack openness,sharing ability and scalability,which make it difficult for many heterogeneous resources to co-exist in the same system. It is also difficult to resolve the conflicts between distributed self-management and centralized scheduling in the system. This paper analyzes the characteristics of resources in the distributed environment and proposes a new resource management architecture by considering the resource aggregation capacity of cloud computing. The architecture includes a universal resource scheduling optimization model which has been applied successfully in double-district multi-ship-scheduling multi-container-yard empty containers transporting of international shipping logistics. Applications in all these domains prove that this new resource management architecture is feasible and can achieve the expected effect. | 张小东 Zhan Dechen Chu Dianhui | 2017 | High Technology Letters2017，23，1： | 1 |
| 19 | Multi-plant purchase co-ordination based on multi-agent system in an ATO environment 显示文摘 | OBOULHAS T XU XIAOFEI ZHAN DECHEN | 2005 | Journal of Manufacturing Technology Management2005，16，6： | 1 |
| 20 | Methicillin- resistant Staphylococcus aureus: Prevalence and current susceptibility pattern in Sikkim显示文摘 | Dechen C Tsering Ranabir Pal Sumit Kar | 2011 | J Glob Infect Dis2011，3，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员