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| 1 | 水飞蓟素的肝脏保护作用研究(英文)显示文摘目的:研究水飞蓟素对人正常肝细胞(Chang细胞株)的保护作用,尤其是其抗氧化活性和对细胞抗凋亡的保护作用。方法:采用400μmol/L H2O2处理Chang细胞20 min后,通过二氯荧光黄(dichlorofluorescein,DCF)荧光强度检测细胞内自由基水平,并检测了细胞活性及细胞内Bax表达水平和ATP水平。结果:水飞蓟素明显降低了DCF荧光信号,显示细胞内自由基生成减少。MTT实验结果显示水飞蓟素可增强细胞活性,增加细胞内ATP水平,而减少促凋亡蛋白Bax的转录和表达水平。结论:水飞蓟素可抑制Bas表达,具有保护细胞抗氧化应激所致自由基损伤的作用。水飞蓟素可作为治疗特异性肝脏疾病的有效辅助药物。 | Frank J.Burczynski 汪谷奇 David Nguyen 陈宇非 Howard J.Smith 巩跃文 | 2012 | 中南大学学报(医学版)2012，37，1： | 4 |
| 2 | Ground-Based LiDAR Improves Phenotypic Repeatability of Above-Ground Biomass and Crop Growth Rate in Wheat显示文摘Highly repeatable,nondestructive,and high-throughput measures of above-ground biomass(AGB)and crop growth rate(CGR)are important for wheat improvement programs.This study evaluates the repeatability of destructive AGB and CGR measurements in comparison to two previously described methods for the estimation of AGB from LiDAR:3D voxel index(3DVI)and 3D profile index(3DPI).Across three field experiments,contrasting in available water supply and comprising up to 98 wheat genotypes varying for canopy architecture,several concurrent measurements of LiDAR and AGB were made from jointing to anthesis.Phenotypic correlations at discrete events between AGB and the LiDAR-derived biomass indices were significant,ranging from 0.31(P<0:05)to 0.86(P<0:0001),providing confidence in the LiDAR indices as effective surrogates for AGB.The repeatability of the LiDAR biomass indices at discrete events was at least similar to and often higher than AGB,particularly under water limitation.The correlations between calculated CGR for AGB and the LiDAR indices were moderate to high and varied between experiments.However,across all experiments,the repeatabilities of the CGR derived from the LiDAR indices were appreciably greater than those for AGB,except for the 3DPI in the water-limited environment.In our experiments,the repeatability of either LiDAR index was consistently higher than that of AGB,both at discrete time points and when CGR was calculated.These findings provide promising support for the reliable use of ground-based LiDAR,as a surrogate measure of AGB and CGR,for screening germplasm in research and wheat breeding. | David M.Deery Greg J.Rebetzke Jose A.Jimenez-Berni Anthony G.Condon David J.Smith Kathryn M.Bechaz William D.Bovill | 2020 | Plant Phenomics2020，2，1： | 4 |
| 3 | The mitochondria‐targeted anti‐oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients显示文摘 | Edward J.Gane FrankWeilert David W.Orr Geraldine F.Keogh MichaelGibson Michelle M.Lockhart Christopher M.Frampton Kenneth M.Taylor Robin A. J.Smith Michael P.Murphy | 2010 | Liver International2010，，7： | 2 |
| 4 | The mitochondria‐targeted anti‐oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients显示文摘 | Edward J.Gane FrankWeilert David W.Orr Geraldine F.Keogh MichaelGibson Michelle M.Lockhart Christopher M.Frampton Kenneth M.Taylor Robin A. J.Smith Michael P.Murphy | 2010 | Liver International2010，，7： | 1 |
| 5 | Cardiorespiratory and muscular fitness associations with older adolescent cognitive control显示文摘Background:Participation in physical activity supports greater cardiorespiratory fitness(CRF),a correlate of cognitive control.However,the relationship between muscular fitness(MF)and cognitive control is less clear.The present study investigated the differential relationship of CRF and MF with cognitive control in older adolescents.Methods:This cross-sectional study involved students(1517 years old,n=541,43%female)from 20 secondary schools who completed tests of inhibition(modified flanker task),working memory(n-back task),CRF(Progressive Aerobic Cardiovascular Endurance Run),and MF(standing long jump and push-up test).Multilevel analyses tested the association between CRF or MF and cognitive outcomes while accounting for the influence of the other fitness variable and relevant demographic factors.Results:CRF predicted response accuracy during incongruent flanker trials,the condition requiring greater inhibition.For the working memory task,CRF predicted greater target accuracy and greater d’scores on the 1-back task,requiring lesser amounts of working memory.In the 2-back task,which requires greater amounts of working memory,CRF also predicted greater target and non-target accuracy and d’scores.Comparatively,MF did not predict any cognitive outcomes after adjustment for CRF.Conclusion:CRF was selectively related to better performance during task conditions that require greater amounts of inhibition and working memory.This finding suggests that CRF,but not MF,may benefit cognitive control in older adolescents.This selective influence of CRF on older adolescents’cognition highlights the value of aerobic physical activity. | Tatsuya T.Shigeta Angus A.Leahy Jordan J.Smith Narelle Eather David R.Lubans Charles H.Hillman | 2021 | Journal of Sport and Health Science2021，10，1： | 1 |
| 6 | Comprehensive, in operando, and correlative investigation of defects and their impact on device performance显示文摘Despite the long history of research that has focused on the role of defects on device performance, the studies have not always been fruitful. A major reason is because these defect studies have typically been conducted in a parallel mode wherein the semiconductor wafer was divided into multiple pieces for separate optical and structural characterization, as well as device fabrication and evaluation. The major limitation of this approach was that either the defect being investigated by structural characterization techniques was not the same defect that was affecting the device performance or else the defect was not characterized under normal device operating conditions. In this review, we describe a more comprehensive approach to defect study, namely a series mode, using an array of spatially-resolved optical, electrical, and structural characterization techniques, all at the individual defect level but applied sequentially on a fabricated device. This novel sequential approach enables definitive answers to key questions, such as:(ⅰ) how do individual defects affect device performance?(ⅱ) how does the impact depend on the device operation conditions?(ⅲ) how does the impact vary from one defect to another? Implementation of this different approach is illustrated by the study of individual threading dislocation defects in GaAs solar cells. Additionally,we briefly describe a 3-D Raman thermometry method that can also be used for investigating the roles of defects in high power devices and device failure mechanisms. | Yong Zhang David J.Smith | 2022 | Journal of Semiconductors2022，43，4： | 1 |
| 7 | Helicobacter pylori infection and the risks of Barrett’s oesophagus: A population‐based case–control study显示文摘 | Aaron P.Thrift NirmalaPandeya Kylie J.Smith Adèle C.Green Nicholas K.Hayward Penelope M.Webb David C.Whiteman | 2012 | Int J Cancer2012，，10： | 1 |
| 8 | 查看详情显示文摘 | Martin Endemann Philippe Gaz é David J.Smith Karl Hoeming Burkhard Fladt Roland Gefiner | | 0，，： | 1 |
| 9 | Understanding Policy Networks:towards a Dialectical Approach显示文摘 | Marsh David Martin J.Smith | | 0，，： | 1 |
| 10 | 如果世界是个一百人的村落显示文摘如果我们把全世界的人口按照现有比例压缩成一个100人的村子,情况就会是这样:这个村子里有:61个亚洲人,12个欧洲人13人来自西半球的南、北美洲13个非洲人,剩下的那个人来自南太平洋52人是女性,48人是男性70人是有色人种。 | David J.Smith Shelath Armstrory 杨晓玲 | 2003 | 新东方英语(中英文版)2003，0，8： | 0 |
| 11 | 系统评价类综述与普通综述:标准及复杂性探究显示文摘本文是由Robert T.Sataloff,Ehab Y.Hanna,李大庆教授等20余位耳鼻咽喉头颈外科领域知名期刊主编共同撰写的一篇针对系统评价等不同类型综述文章标准及复杂性分析的述评类文章。该文章将于2021年7月在包括《世界耳鼻咽喉头颈外科杂志(英文)》,Journal of Voice,Head&Neck,American Journal of Rhinology&Allergy,The Laryngoscope等20余本国际知名耳鼻咽喉头颈外科期刊同时以英文版本刊出,为了便于中国读者对该内容进行深入了解,在获得相应授权后,本刊特别邀请刘争教授团队对该文章进行翻译,同期在本刊以中文版本刊登。希望本文对广大读者在撰写综述类文章时有所裨益。 | Robert T.Sataloff Matthew L.Bush Rakesh Chandra Douglas Chepeha Brian Rotenberg Edward W.Fisher David Goldenberg Ehab Y.Hanna Joseph E.Kerschner Dennis H.Kraus John H.Krouse Daqing Li Michael Link Lawrence R.Lustig Samuel H.Selesnick Raj Sindwani Richard J.Smith James R.Tysome Peter C.Weber D.Bradley Welling 张心浩(译) 刘争(译) | 2021 | 中华耳鼻咽喉头颈外科杂志2021，56，7： | 0 |
| 12 | Impact of Varying Light and Dew on Ground Cover Estimates from Active NDVI,RGB,and LiDAR显示文摘Canopy ground cover(GC)is an important agronomic measure for evaluating crop establishment and early growth.This study evaluates the reliability of GC estimates,in the presence of varying light and dew on leaves,from three different ground-based sensors:(1)normalized difference vegetation index(NDVI)from the commercially available GreenSeeker®;(2)RGB images from a digital camera,where GC was determined as the portion of pixels from each image meeting a greenness criterion(i.e.,ðGreen−RedÞ/ðGreen+RedÞ>0);and(3)LiDAR using two separate approaches:(a)GC from LiDAR red reflectance(whereby red reflectance less than five was classified as vegetation)and(b)GC from LiDAR height(whereby height greater than 10 cm was classified as vegetation).Hourly measurements were made early in the season at two different growth stages(tillering and stem elongation),among wheat genotypes highly diverse for canopy characteristics.The active NDVI showed the least variation through time and was particularly stable,regardless of the available light or the presence of dew.In addition,between-sample-time Pearson correlations for NDVI were consistently high and significant(P<0:0001),ranging from 0.89 to 0.98.In comparison,GC from LiDAR and RGB showed greater variation across sampling times,and LiDAR red reflectance was strongly influenced by the presence of dew.Excluding times when the light was exceedingly low,correlations between GC from RGB and NDVI were consistently high(ranging from 0.79 to 0.92).The high reliability of the active NDVI sensor potentially affords a high degree of flexibility for users by enabling sampling across a broad range of acceptable light conditions. | David M.Deery David J.Smith Robert Davy Jose A.Jimenez-Berni Greg J.Rebetzke Richard A.James | 2021 | Plant Phenomics2021，3，1： | 0 |
| 13 | Systematic and other reviews: Criteria and complexities显示文摘Review articles can be extremely valuable.They synthesize information for readers,often provide clarity and valuable insights into a topic;and good review articles tend to be cited frequently.Review articles do not require Institutional Review Board(IRB)approval if the data reviewed are public(including private and government databases)and if the articles reviewed have received IRB approval previously. | Robert T.Sataloff Matthew L.Bush Rakesh Chandra Douglas Chepeha Brian Rotenberg Edward W.Fisher David Goldenberg Ehab Y.Hanna Joseph E.Kerschner Dennis H.Kraus John H.Krouse Daqing Li Michael Link Lawrence R.Lustig Samuel H.Selesnick Raj Sindwani Richard J.Smith James R.Tysome Peter C.Weber D.Bradley Welling | 2021 | World Journal of Otorhinolaryngology-Head and Neck Surgery2021，7，3： | 0 |
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