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    题名 作者 年代 出处 被引量
1The relationship between reduction in low-density lipoprotein cholesterol by statins and reduction in risk of cardiovascular outcomes: An updated meta-analysis显示文摘Philippa J. Delahoy Dianna J. Magliano Kate Webb Mendel Grobler Danny Liew 2009Clinical Therapeutics2009,,2:2
2925j Optimising post-operative Crohn’s disease management: best drug therapy alone versus colonoscopic monitoring with treatment step-up. The POCER study.显示文摘Peter De Cruz Michael A. Kamm Amy L. Hamilton Kathryn J. Ritchie Soula Krejany Alexandra Gorelik Danny Liew Lani Prideaux Ian C. Lawrance Jane M. Andrews Peter A. Bampton Miles Sparrow Timothy H. Florin Peter R. Gibson Henry Debinski Richard B. Gearry Fin 2013Gastroenterology2013,,5:1
3Cost-effectiveness of Crohn's disease post-operative care显示文摘AIM: To define the cost-effectiveness of strategies, including endoscopy and immunosuppression, to prevent endoscopic recurrence of Crohn's disease following intestinal resection.METHODS: In the 'POCER' study patients undergoing intestinal resection were treated with post-operative drug therapy. Two thirds were randomized to active care(6 mo colonoscopy and drug intensification for endoscopic recurrence) and one third to drug therapy without early endoscopy. Colonoscopy at 18 mo and faecal calprotectin(FC) measurement were used to assess disease recurrence. Administrative data, chart review and patient questionnaires were collected prospectively over 18 mo.RESULTS: Sixty patients(active care n = 43, standardcare n = 17) were included from one health service. Median total health care cost was $6440 per patient. Active care cost $4824 more than standard care over 18 mo. Medication accounted for 78% of total cost, of which 90% was for adalimumab. Median health care cost was higher for those with endoscopic recurrence compared to those inremission [ $ 26347( IQR 25045-27485) vs $2729(IQR 1182-5215), P < 0.001]. FC to select patients for colonoscopy could reduce cost by $1010 per patient over 18 mo. Active care was associated with 18% decreased endoscopic recurrence, costing $861 for each recurrence prevented. CONCLUSION: Post-operative management strategies are associated with high cost, primarily medication related. Calprotectin use reduces costs. The long term cost-benefit of these strategies remains to be evaluated.Emily K Wright Michael A Kamm Peter Dr Cruz Amy L Hamilton Kathryn J Ritchie Sally J Bell Steven J Brown William R Connell Paul V Desmond Danny Liew 2016World Journal of Gastroenterology2016,22,14:1
4Results of a Markov model analysis to assess the cost-effectiveness of statin therapy for the primary prevention of cardiovascular disease in Korea: The Korean Individual-Microsimulation Model for Cardiovascular Health Interventions显示文摘Hye-Young Kang Su-Kyoung Ko Danny Liew 2009Clinical Therapeutics2009,,:1
5Risk stratification for coronary artery disease in multi-ethnic populations:Are there broader considerations for cost efficiency?显示文摘Coronary artery disease(CAD) screening and diagnosis are core cardiac specialty services.From symptoms,autopsy correlations supported reductions in coronary blood flow and dynamic epicardial and microcirculatory coronaries artery disease as etiologies.While angina remains a clinical diagnosis,most cases require correlation with a diagnostic modality.At the onset of the evidence building process much research,now factored into guidelines were conducted among population and demographics that were homogenous and often prior to newer technologies being available.Today we see a more diverse multi-ethnic population whose characteristics and risks may not consistently match the populations from which guideline evidence is derived.While it would seem veryunlikely that for the majority,scientific arguments against guidelines would differ,however from a translational perspective,there will be populations who differ and importantly there are cost-efficacy questions,e.g.,the most suitable first-line tests or what parameters equate to an adequate test.This article reviews non-invasive diagnosis of CAD within the context of multi-ethnic patient populations.Pupalan Iyngkaran William Chan Danny Liew Jalal Zamani John D Horowitz Michael Jelinek David L Hare James A Shaw 2019World Journal of Methodology2019,9,1:0
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