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| 1 | 3-Dimensional liver volume assessment in patients with hepatitis B virus-related liver cirrhosis during long-term oral nucleos(t)ide analogues therapy显示文摘AIM To assess the effect of long-term oral nucleos(t)ide analogues(NUCs) therapy on liver volume change in patients with suppress hepatitis B virus(HBV)-related liver cirrhosis.METHODS We reviewed the data of na?ve patients with HBVrelated liver cirrhosis, who had taken oral NUCs therapy, between 2003 and 2007 at Chonbuk University Hospital. We analyzed two consecutive sets of abdominal computerized tomography scans-one at the time oftreatment initiation and another at the second-year follow-up. Liver volume was calculated by 3-dimensional liver extraction volumetry program.RESULTS A total of 55 patients(34 males) were included. There was 114.3 m L ± 167.8 m L(12.9% ± 17.9%) of increase in liver volume during the two years of NUCs therapy(993.8 m L ± 242.8 m L at baseline vs 1108.1 m L ± 263.3 m L at two-year follow-up, P < 0.001). The ratio of the measured baseline liver volume to the estimated standard liver volume was improved from 70.8% to 78.0%. An increase in liver volume was shown not only in patients with compensated cirrhosis(P = 0.046) but also in those with decompensated cirrhosis(P < 0.001). Significant factors for volume increases were Child-Turcotte-Pugh grade and model for end-stage liver disease score improvement without virological breakthrough. In multiple linear regression analysis, delta albumin and delta alanine aminotransferase levels showed a significant association with the increase in liver volume(P = 0.002 and 0.005, respectively).CONCLUSION Long-term oral NUCs therapy in patients with HBVrelated liver cirrhosis lead to significant increase in liver volume assessed with 3-dimensional liver extraction volumetry program. | Chang Hun Lee In Hee Kim Jin Chang Moon Seung Young Seo Seong Hun Kim Sang Wook Kim Seung Ok Lee Soo Teik Lee Dae Ghon Kim Jae Do Yang Hee Chul Yu | 2017 | World Journal of Gastroenterology2017，23，2： | 6 |
| 2 | Neoadjuvant Chemoradiotherapy Affects the Indications for Lateral Pelvic Node Dissection in Mid/Low Rectal Cancer with Clinically Suspected Lateral Node Involvement: A Multicenter Retrospective Cohort Study显示文摘 | Heung-Kwon Oh Sung-Bum Kang Sung-Min Lee Soo Young Lee Myoung Hun Ihn Duck-Woo Kim Ji Hoon Park Young Hoon Kim Kyung Ho Lee Jae-Sung Kim Jin Won Kim Jee Hyun Kim Tae-Young Chang Sung-Chan Park Dae Kyung Sohn Jae Hwan Oh Ji Won Park Seung-Bum Ryoo Seung-Yo | 2014 | Annals of Surgical Oncology2014，，： | 2 |
| 3 | Enzyme-amplified SERS immunoassay with Ag-Au bimetallic SERS hot spots显示文摘Surface-enhanced Raman scattering(SERS)enables rapid detection of single molecules with high specificity.However,quantitative and sensitive SERS analysis has been a challenge due to the lack of reliable SERS-active materials.In this study,we developed a quantitative SERS-based immunoassay using enzyme-guided Ag growth on Raman labeling compound(RLC)-immobilized gold nanoparticle(Au NP)-assembled silica NPs(SiO2@Au-RLC@Ag).The enzyme amplified Ag+reduction as well as Ag growth on the RLC-immobilized Au NP-assembled silica NPs(SiO2@Au-RLC),which resulted in a significant increase in SERS signal.In the presence of target antigens such as immunoglobulinG(IgG)or prostate-specific antigen(PSA),Ab1-Antigen-Ab2 immune complex with alkaline phosphatase triggered an enzyme-catalyzed reaction to convert 2-phospho-L-ascorbic acid(2-phospho-L-AA)to ascorbic acid(AA).As produced AA reduced Ag+to Ag,forming an Ag hot spot on the surface of SiO2@Au-RLC,which enhanced the SERS signal of SiO2@Au-RLC@Ag in a solution with a target antigen concentration.The plasmonic immunoassay for IgG detection showed a high linearity of SERS intensity in the range of 0.6 to 9.0 ng/mL with a detection limit(LOD)of 0.09 ng/mL,while an LOD of 0.006 ng/mL was obtained for PSA.The results indicate that the sensitivity of our novel SERS-based immunoassay is higher than that of conventional enzyme-based colorimetric immunoassays. | Xuan-Hung Pham Eunil Hahm Tae Han Kim Hyung-Mo Kim Sang Hun Lee Sang Chul Lee Homan Kang Ho-Young Lee Dae Hong Jeong Hak Soo Choi Bong-Hyun Jun | 2020 | Nano Research2020，13，12： | 2 |
| 4 | Modelling of the thermal behaviour of an ultracapacitor for a 42-V automotive electrical system显示文摘 | Dae Hun Lee Ui Seong Kim Chee Burm Shin | 2008 | Journal of Power Sources2008，175，： | 1 |
| 5 | Expression of Cancer-Testis Antigens MAGE-A3/6 and NY-ESO-1 in Non-Small-Cell Lung Carcinomas and Their Relationship with Immune Cell Infiltration显示文摘 | Sang Hyun Kim Sangyull Lee Chang Hun Lee Min Ki Lee Young Dae Kim Dong Hoon Shin Kyung Un Choi Jee Yeon Kim Do Youn Park Mee Young Sol | 2009 | Lung2009，，6： | 1 |
| 6 | Clinical Outcomes of Patients with Liver Cirrhosis Who Underwent Curative Surgery for Gastric Cancer: A Retrospective Multi-center Study显示文摘 | Hyun Joo Jang Jung Han Kim Hun Ho Song Kyung Hee Woo Mi Kim Sea Hyub Kae Jin Lee Ji Wong Cho Jung Hun Kang Soon Il Lee Soo Jung Gong Jung Ae Lee Dae Young Zang | 2008 | Digestive Diseases and Sciences2008，，2： | 1 |
| 7 | Simultaneous carbon capture and nitrogen removal during supercritical water oxidation显示文摘 | Young Ho Shin Hong-shik Lee Bambang Veriansyah Jaehoon Kim Dae Sung Kim Hun Wook Lee Yong-Suk Youn Youn-Woo Lee | 2012 | The Journal of Supercritical Fluids2012，，： | 1 |
| 8 | Modelling of the thermal behaviour of an ultracapacitor for a 42 V automotive electrical system显示文摘 | Dae Hun Lee Ui Seong Kim Chee Burm Shin | 2008 | Journal of Power Sources2008，175，1： | 1 |
| 9 | p53 alteration independently predicts poor outcomes in patients with endometrial cancer: A clinicopathologic study of 131 cases and literature review显示文摘 | Eun-Ju Lee Tae-Joong Kim Dae Shick Kim Chel Hun Choi Jeong-Won Lee Je-Ho Lee Duk-Soo Bae Byoung-Gie Kim | 2009 | Gynecologic Oncology2009，，： | 1 |
| 10 | Direct lipiodol injection used for a radio-opaque lung marker: stability and histopathologic effects显示文摘 | Woon Jung Kwon Hak Jin Kim Yeon Joo Jeong Chang Hun Lee Kun-Il Kim Yeong Dae Kim Jong Hwa Lee | 2011 | Experimental Lung Research2011，，5： | 1 |
| 11 | Phase I study of autologous dendritic cell tumor vaccine in patients with non-small cell lung cancer显示文摘 | Soo-Jung Um Young Jin Choi Ho-Jin Shin Cheol Hun Son You-Soo Park Mee Sook Roh Yun Seong Kim Young Dae Kim Soo-Keol Lee Min Ho Jung Min Ki Lee Choonhee Son Pil Jo Choi Jooseop Chung Chi-Dug Kang Eun-Yup Lee | 2010 | Lung Cancer2010，，： | 1 |
| 12 | Effects of mechanical vibration on critical heat flux in vertical annulus tube显示文摘 | Dae Hun Kim Yong Ho Lee Soon Heung Chang | 2007 | Nuclear Engineering and Design2007，，237： | 1 |
| 13 | Transmesocolic hernia with strangulation in a patient without surgical history: Case report显示文摘Transmesenteric hernias have bimodal distribution and occur in both pediatric and adult patients. In the adult population, the cause is iatrogenic, traumatic, or inflammatory. We report a case of transmesocolic hernia in an elderly person without any preoperative history. An 84-year-old Korean female was admitted with midabdominal pain and distension for 1 d. On abdominal computed tomography, we diagnosed transmesocolic hernia with strangulated small bowel obstruction, and performed emergency surgery. The postoperative period was uneventful and she was discharged 11 d after surgery. Hence, it is important to consider the possibility of transmesocolic hernia in elderly patients with signs and symptoms of intestinal obstruction, even in cases with no previous surgery. 2013 Baishideng. All rights reserved. | Peel Jung Min Dae Kim Tae Hyun Ryu Sung Ho Choi Han Se Kim Kang Hun Lee Jhong Hyun Park | 2013 | World Journal of Gastroenterology2013，19，12： | 1 |
| 14 | Monitoring of sequencing batch reactor for nitrogen and phosphorus removal using neural networks 显示文摘 | Sung Hun Hong Min Woo Lee Dae Sung Lee | 2007 | Biochemical Engineering Journal2007，35，3： | 1 |
| 15 | Common bile duct stone caused by a phytobezoar显示文摘 | Tae Oh Kim Seong Hun Lee Gwang Ha Kim Jeong Heo Dae Hwan Kang Geun Am Song Jun Woo Lee Mong Cho | 2006 | Gastrointestinal Endoscopy2006，，2： | 1 |
| 16 | Monitoring of sequencing batch reactor for nitrogen and phosphorus removal using neural networks 显示文摘 | Sung Hun Hong Min Woo Lee Dae Sung Leem et el | 2007 | Biochemical Engineering Journal2007，35，3： | 1 |
| 17 | Low temperature-mediated repression and far-red light-mediated induction determine morning FLOWERING LOCUS T expression levels显示文摘In order to flower in the appropriate season,plants monitor light and temperature changes and alter downstream pathways that regulate florigen genes such as Arabidopsis(Arabidopsis thaliana)FLOWERING LOCUS T(FT).In Arabidopsis,FT messenger RNA levels peak in the morning and evening under natural long-day conditions(LDs).However,the regulatory mechanisms governing morning FT induction remain poorly understood.The morning FT peak is absent in typical laboratory LDs characterized by high red:far-red light(R:FR)ratios and constant temperatures.Here,we demonstrate that ZEITLUPE(ZTL)interacts with the FT repressors TARGET OF EATs(TOEs),thereby repressing morning FT expression in natural environments.Under LDs with simulated sunlight(R:FR=1.0)and daily temperature cycles,which are natural LD-mimicking environmental conditions,FT transcript levels in the ztl mutant were high specifically in the morning,a pattern that was mirrored in the toe1 toe2 double mutant.Low night-to-morning temperatures increased the inhibitory effect of ZTL on morning FT expression by increasing ZTL protein levels early in the morning.Far-red light counteracted ZTL activity by decreasing its abundance(possibly via phytochrome A(phyA))while increasing GIGANTEA(GI)levels and negatively affecting the formation of the ZTL-GI complex in the morning.Therefore,the phyA-mediated high-irradiance response and GI play pivotal roles in morning FT induction.Our findings suggest that the delicate balance between low temperature-mediated ZTL activity and the far-red light-mediated functions of phyA and GI offers plants flexibility in fine-tuning their flowering time by controlling FT expression in the morning. | Hayeon Kim Hye Won Kang Dae Yeon Hwang Nayoung Lee Akane Kubota Takato Imaizumi Young Hun Song | 2024 | Journal of Integrative Plant Biology2024，66，1： | 0 |
| 18 | Erratum to: Enzyme-amplified SERS immunoassay with Ag-Au bimetallic SERS hot spots显示文摘Erratum to Nano Research 2020,13(12):3338-3346 htts://doi.org/00.1007/s12274-020-3014-3 One author name and corresponding affiliation of the original version of this article were unfortunately mislabeled. | Xuan-Hung Pham Eunil Hahm Tae Han Kim Hyung-Mo Kim Sang Hun Lee SangChul Lee Homan Kang Ho-Young Lee Dae Hong Jeong Hak Soo Choi Bong-Hyun Jun | 2021 | Nano Research2021，14，3： | 0 |
| 19 | Efficiency Improvement of 590 nm AIGalnP Light Emitting Diode with a Reflective Top Electrode显示文摘 | Hyung Joo Lee Young Dae Cho Young Jin Kim Choong Hun Lee Jae Hoon Kim Hwa Sub Oh Su Chang Ahn | 2014 | Journal of Physical Science and Application2014，4，2： | 0 |
| 20 | Real-world outcomes of ibrutinib therapy in Korean patients with relapsed or refractory mantle cell lymphoma:amulticenter,retrospective analysis显示文摘Dear Editor,Despite the introduction of novel front-line therapies including rituximab plus high-dose cytarabine followed by consolidative autologous stem cell transplantation(ASCT)and salvage therapy with bendamustine,lenalidomide or bortezomib,mantle cell lymphoma(MCL)is still considered incurable and most patients experience relapse or refractory(RR)disease. | Jun Ho Yi Seok Jin Kim Dok Hyun Yoon Cheolwon Suh Myung Hee Chang Deok Hwan Yang Jae-Cheol Jo Shin Young Hyun Hyeon-Seok Eom Jeong-Ok Lee Ji Hyun Kwon Sang Hoon Han Seung-Shin Lee Jae-Yong Kwak Se Hyung Kim Dae Sik Kim Ji Hyun Lee Sung Yong Oh Hun Mo Ryoo Hyo Jung Kim Won Seog Kim | 2021 | Cancer Communications2021，41，3： | 0 |
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