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| 1 | Management of pancreaticobiliary disease using a new intra-ductal endoscope:The Texas experience显示文摘AIM:To evaluate a new single-operator mini-endoscope, Spyglass,for its performance,feasibility and safety in the management of pancreaticobiliary disease. METHODS:In a multicenter retrospective analysis of patients undergoing intraductal endoscopy,we evaluated 128 patients(71 men,mean age 57.6 years).Indications were therapeutic(TX)in 72(56%) and diagnostic(DX)in 56(44%). RESULTS:Peroral endoscopy was performed in 121 and percutaneous in seven.TX indications included CBD stones in 41,PD stones in six,and biliary strictures in 25.DX indications included abnormal LFT’s in 15, abnormal imaging in 38 and cholangiocarcinoma staging in three.Visualization of the stone(s)was considered good in 31,fair in six,and poor in four. Advancement of the electrohydraulic lithotripsy probe was not possible in three patients and proper targeting of the lesion was partial in four patients.A holmium laser was used successfully in three patients.Ductal clearance was achieved in 37 patients after one procedure and in four patients after two procedures.Diagnosis of biliary strictures was modified in 20/29 and confirmed to be malignant in 10/23.Of the modified patients,no diagnosis was available in 17.Spyglass demonstrated malignancy in 8/17 and non-malignancy in nine.Suspected pathology by imaging studies and abnormal LFT’s was modified in 43/63(66%).Staging of cholangiocarcinoma demonstrated multicentric cholangiocarcinoma in 2/3.There was no morbidity associated with the use of Spyglass. CONCLUSION:Spyglass Spyscopeis a first generation, single operator miniature endoscope that can evaluate and treat various biliary and pancreatic tract diseases. | Douglas S Fishman Paul R Tarnasky Sandeep N Patel Isaac Raijman | 2009 | World Journal of Gastroenterology2009，15，11： | 22 |
| 2 | Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial显示文摘 | Stephen B Hanauer Brian G Feagan Gary R Lichtenstein Lloyd F Mayer S Schreiber Jean Frederic Colombel Daniel Rachmilewitz Douglas C Wolf Allan Olson Weihang Bao Paul Rutgeerts | 2002 | The Lancet2002，，9317： | 6 |
| 3 | The modified method of charawith adjusted advection显示文摘 | Douglas J J r Huang C S Pereira F | 1999 | Numer Math1999，83，： | 2 |
| 4 | The relationship between atopy and chronic rhinosinusitis显示文摘 | Robinson S Douglas R Wormald P J | 2006 | Am J Rhinol2006，20，6： | 1 |
| 5 | Measuring velocity dispersion and attenuation in the exploration seismic frequency band显示文摘 | Langqiu F S Bernd M Douglas R S | 2009 | Geophysics2009，72，2： | 1 |
| 6 | Environmentalstability of selected petroleum hydrocarbon source and weatheringratios显示文摘 | Douglas G S Bence A E Prince R C | 1996 | Environmental Science&Technology1996，30，7： | 1 |
| 7 | An introduction to DNA microarrays for gene expression analysis显示文摘 | Karakach T K Flight R M Douglas S E | 2010 | Chemometrics Intell Lab Syst2010，104，1： | 1 |
| 8 | Health effects of recreational exposure to cyanobacteria(bluegreen algae) during recreational water-related activities显示文摘 | Pilotto L S Douglas R M Burch M D | 1997 | Australian and New Zealand Journal of Public Health1997，21，： | 1 |
| 9 | Multicriteria optimization with a multiobjective golden section line search显示文摘 | Douglas A G V Ricardo H C T Rodney R S | 2012 | Mathematical Programming2012，131，12： | 1 |
| 10 | Geotextile tubes as submerged dykes for shoreline management in Malaysia显示文摘 | LEE E C DOUGLAS R S | 2012 | Geotextiles and Geomembranes2012，30，： | 1 |
| 11 | First break timing: arrival onset times by direct correlation显示文摘 | Joseph B M Douglas R S | 1999 | Geophysics1999，64，5： | 1 |
| 12 | Structure - function analysis of a conserved aromatic cluster in the N - terminal domain of human epidermal growth factor 显示文摘 | MARY B M DOUGLAS K TADAKI S R | 1998 | Protein Engineering1998，11，11： | 1 |
| 13 | Soil classification using electric cone penetrometer, symposium on cone penetration testing and experience 显示文摘 | Douglas J B Olsen R S | 1981 | Geotechnieal Engineering Division: ASCE1981，，： | 1 |
| 14 | Identification and expression analysis of hepcidin-like antimicrobial peptides in bony fish显示文摘 | Douglas S E Gallant J W Liebscher R S | 2003 | Dev Comp Immunol2003，27，： | 1 |
| 15 | Vascular Endothelial Growth Factor (VEGF) isoform expression and activity in human and murine lung injury显示文摘 | Medford A R L Douglas S K Godinho S I H | 2009 | Respiratory Research2009，10，1： | 1 |
| 16 | Direct detection of 16SrRNA in soil extracts by using oligonucleotide mi- croarrays 显示文摘 | Jack S Douglas R C Fred J B | 2001 | Applied and Environmental Microbiology2001，67，10： | 1 |
| 17 | Three-dimen-sional structure of an antigenic mutant of the influenza virushemagglutinin显示文摘 | Knossow M Daniels R S Douglas A R | 1984 | Nature1984，311，5987： | 1 |
| 18 | Sensor for transient heat flux at a surface with throughflow 显示文摘 | Polat S Heiningen A R P V Douglas W J M | 1991 | International Journal of Heat and Mass Transfer1991，34，6： | 1 |
| 19 | Multilineage potential of adult human mesenchymal stem cells 显示文摘 | Pittenger MF Mackay AM Beck SC Jaiswal RK Douglas R Mosca JD Moorman MA Simonetti DW Craig S Marshak DR | 1999 | Science1999，284，： | 1 |
| 20 | Identification andexpression analysis of hepcidin-like antimicrobial peptides inbony fish显示文摘 | Douglas S E Gallant J W Liebscher R S | 2003 | Developmental and Comparative Immunology2003，27，67： | 1 |
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