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| 1 | Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria显示文摘 | Bruno Dubois Howard H Feldman Claudia Jacova Harald Hampel José Luis Molinuevo Kaj Blennow Steven T DeKosky Serge Gauthier Dennis Selkoe Randall Bateman Stefano Cappa Sebastian Crutch Sebastiaan Engelborghs Giovanni B Frisoni Nick C Fox Douglas Galasko Ma | 2014 | Lancet Neurology2014，，6： | 7 |
| 2 | Integrated photonic systems based on transformation optics enabled gradient index devices显示文摘Integrated photonics is expected to play an increasingly important role in optical communications,imaging,computing and sensing with the promise for significant reduction in the cost and weight of these systems.Future advancement of this technology is critically dependent on an ability to develop compact and reliable optical components and facilitate their integration on a common substrate.Here we reveal,with the utility of the emerging transformation optics technique,that functional components composed of planar gradient index materials can be designed and readily integrated into photonic circuits.The unprecedented design flexibility of transformation optics allows for the creation of a number of novel devices,such as a light source collimator,waveguide adapters and a waveguide crossing,which have broad applications in integrated photonic chips and are compatible with current fabrication technology.Using the finite-difference time-domain method,we perform full-wave numerical simulations to demonstrate their superior optical performance and efficient integration with other components in an on-chip photonic system.These components only require spatially-varying dielectric materials with no magnetic properties,facilitating low-loss,broadband operation in an integrated photonic environment. | Qi Wu Jeremiah P Turpin Douglas H Werner | 2012 | Light(Science & Applications)2012，1，1： | 6 |
| 3 | Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease显示文摘BACKGROUND Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin(FC)and fecal lactoferrin(FL)in monitoring inflammatory bowel diseases(IBD)-Crohn's disease(CD)and ulcerative colitis(UC).However,their correlation to endoscopic scores,disease severity and affected intestinal surface has not been extensively investigated.AIM To correlate FL,and for comparison white blood cell(WBC)and C-reactive protein(CRP),with endoscopic scores,disease extent and location in CD and UC.METHODS Retrospective analysis in 188 patients who had FL,CRP and WBC determined within 30 d of endoscopy.Disease location,disease extent(number of intestinal segments involved),disease severity(determined by endoscopic scores),timing of FL testing in relation to colonoscopy,as well as the use of effective fast acting medications(steroids and biologics)between colonoscopy and FL measurement,were recorded.RESULTS In 131 CD and 57 UC patients,both CRP and FL-but not WBC-distinguished disease severity(inactive,mild,moderate,severe).In patients receiving fastacting(steroids or biologics)treatment in between FL and colonoscopy,FL showed a higher correlation to endoscopic scores when tested before vs after the procedure(r=0.596,P<0.001,vs r=0.285,P=0.15 for the Simple Endoscopic Score for CD;and r=0.402,P=0.01 vs r=0.054 P=0.84 for Disease Activity Index).Finally,FL was significantly correlated with the diseased mucosal surface(colon-ileocolon>small bowel)and the number of inflamed colon segments.CONCLUSION FL and CRP separated disease severity categories with FL showing lower discriminating P-values.FL showed a close correlation with the involved mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before the procedure–this indicating that inflammatory activity changes associated with therapy might be rapidly reflected by FL levels.FL can accurately and timely characterize intestinal inflammation in IBD. | Marrieth G Rubio Kofi Amo-Mensah James M Gray Vu Q Nguyen Sam Nakat Douglas Grider Kim Love James H Boone Dario Sorrentino | 2019 | World Journal of Gastrointestinal Pathophysiology2019，10，5： | 4 |
| 4 | Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal Cancer显示文摘 | Douglas K Rex John H Bond Sidney Winawer Theodore R Levin Randall W Burt David A Johnson Lynne M Kirk Scott Litlin David A Lieberman Jerome D Waye James Church John B Marshall Robert H Riddell | 2002 | The American Journal of Gastroenterology2002，，6： | 3 |
| 5 | Defining the specific physiological requirements for c- Myc in T cell development显示文摘 | Douglas NC Jacobs H Bothwell AL | 2001 | Nat Immunol2001，2，4： | 2 |
| 6 | 全球冰淇淋研究与工艺的发展趋势显示文摘几个世纪前人们就开始生产冰淇淋及相关的甜点。冰淇淋的历史如同一段老照片背后的传奇,让人联想起健康、传统、居家乐趣和民间故事。今天的冰淇淋已经成为一个全球性的大产业,却仍然保持着很多的传统。本文综述了冰淇淋及相关冷冻甜点在配方、原料和加工设备方面的最新进展。 | H Douglas Goff 张智武 | 2007 | 中国乳业2007，，11： | 2 |
| 7 | Miniature reeonfigurable three-dimensional fractal tree antennas 显示文摘 | Joshua S P Douglas H W | 2004 | IEEE Trans on Antennas Propagat2004，52，8： | 1 |
| 8 | Polyurethane/polystyrene one- shot interpenetrating polymer networks with good damping ability:Transition broadening through cross-linking, internetwork grafting and compatibilization 显示文摘 | Douglas H J Schafer F U | 1996 | Polymer Advanced Technology1996，7，4： | 1 |
| 9 | The evolution of manufacturing cells: An action research study显示文摘 | Satya Chakravorty S Douglas N H | 2008 | European J of Operational Research2008，188，1： | 1 |
| 10 | An overview of fractal anten-na engineering research 显示文摘 | DOUGLAS H W SUMAN G | 2003 | IEEE Antennas and Propaga- tion2003，，3： | 1 |
| 11 | Orthodontic tooth movement in the prednisolone-Treated rat显示文摘 | Colin K Laurence J Douglas H | 2000 | Angle Orthod2000，70，： | 1 |
| 12 | Determination of extractable and bound condensed tannin concentrations in forage plants, protein concentrate meals and cereal grains显示文摘 | Terrill T H Rowan A M Douglas G B | 1992 | Journal of the Science of Food and Agriculture1992，58，3： | 1 |
| 13 | 查看详情显示文摘 | T H Douglas A C Joseph | | 0，，： | 1 |
| 14 | A theory of production 显示文摘 | Cobb C W Douglas P H | 1928 | American Economic Review1928，，1： | 1 |
| 15 | Guidelines for Conscious Sedation and Monitoring During Gastrointestinal Endoscopy显示文摘 | J.Patrick Waring Todd H Baron William K Hirota Jay L Goldstein Brian C Jacobson Jonathan A Leighton J.Shawn Mallery Douglas O Faigel | 2003 | Gastrointestinal Endoscopy2003，，3： | 1 |
| 16 | Phenylbutazone toxicosis in equidae a biochemical and pathophysiologic study显示文摘 | Snow DH Douglas TA Thompson H | 1981 | Am J Vet Res1981，42，10： | 1 |
| 17 | Effects of stunting, diarrhoeal disease, and parasitic infection during infancy on cognition in late childhood: a follow-up study显示文摘 | Douglas S Berkman Andres G Lescano Robert H Gilman Sonia L Lopez Maureen M Black | 2002 | The Lancet2002，，9306： | 1 |
| 18 | Human RhoGAP domain- containing proteins: structure, function and evolutionary relation- ships显示文摘 | Peck J Douglas G 4th Wu C H | 2002 | FEBS Lett2002，528，13： | 1 |
| 19 | Mesoscale meteorological and air quality impacts of increased urban albedo and vegetation 显示文摘 | TAHA H DOUGLAS S HANEY J | 1997 | EnergBuild1997，25，： | 1 |
| 20 | High mobility InGaZnO4 thin-film transistors on paper 显示文摘 | LIM W DOUGLAS E A KIM S H | 2009 | Applied Physics Letters2009，94，7： | 1 |
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