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| 1 | 1961-2005年宁夏极端降水事件变化趋势分析显示文摘利用1961—2005年宁夏逐日降水量资料,将降水量划分为9个级别,分析了宁夏45a来各级别降水日数的变化趋势。结果表明:年降水量以平均3.6mm/10a的速率减少;近15a来,冬、春季降水量明显减少,夏、秋季10.0mm以下降水日数明显减少,25.0mm以上降水日数明显增加。以1986年为界的气候变暖前后25.1~50.0mm级别的降水日数夏季和年增加的显著性概率分别达到了5%和1%,降水频率分布呈现向高级别降水量增加的变化趋势。 | 陈晓光 Declan Conway 陈晓娟 郑广芬 | 2008 | 气候变化研究进展2008，4，3： | 51 |
| 2 | 1961—2004年宁夏极端气温变化趋势分析显示文摘利用1961—2004年宁夏逐日最高、最低气温资料,分析了宁夏44a来最高、最低气温的变化趋势。结果表明:宁夏的最高、最低气温表现出了明显的变化趋势,最高气温<0℃的日数减少,>30℃的日数增加;在年平均最低气温升高的同时,极冷日数也在增加,相对于1961—1990年的平均值,20世纪90年代和21世纪最初的4a年极冷日数分别增加了1.1d和0.7d,距平百分率分别达350%和275%。 | 陈晓光 Declan Conway 郑广芬 陈晓娟 | 2008 | 气候变化研究进展2008，4，2： | 34 |
| 3 | Definition and classification of cancer cachexia: an international consensus显示文摘 | Kenneth Fearon Florian Strasser Stefan D Anker Ingvar Bosaeus Eduardo Bruera Robin L Fainsinger Aminah Jatoi Charles Loprinzi Neil MacDonald Giovanni Mantovani Mellar Davis Maurizio Muscaritoli Faith Ottery Lukas Radbruch Paula Ravasco Declan Walsh Andrew | 2011 | Lancet Oncology2011，，5： | 8 |
| 4 | Outcomes after robot-assisted laparoscopic radical prostatectomy显示文摘用 da Vinci 外科的系统的帮助机器人的 laparoscopic 激进分子前列腺切除术(RALRP ) 现在在在经济条件允许这种昂贵的技术的安装的许多国家的普遍使用。自从它首先在 2000 被执行,争吵包围了过程,与加亮支持它的使用的证据的缺乏的许多批评家。尽管有我证实的水平的缺乏,病人的许多大研究不管多么证实了过程可行、安全,与低病态。可得到的长术语的 oncological 数据似乎证明从机器的途径的结果至少传统的开的激进的前列腺切除术匹配那些。功能的结果也似乎令人满意,尽管使随机化控制审判正在缺乏。这份报纸关于 perioperative 数据和复杂并发症和 oncologic 和功能的结果考察 RALRP 的当前的地位。 | Declan G. Murphy Benjamin J. Challacombe Anthony J. Costello | 2009 | Asian Journal of Andrology2009，11，1： | 6 |
| 5 | Protein tyrosine phosphatase non-receptor type 2 andinflammatory bowel disease显示文摘Genome wide association studies have associated single nucleotide polymorphisms within the gene locus encoding protein tyrosine phosphatase non-receptor type 2(PTPN2) with the onset of inflammatory bowel disease(IBD) and other inflammatory disorders. Expression of PTPN2 is enhanced in actively inflamed intestinal tissue featuring a marked up-regulation in intestinal epithelial cells. PTPN2 deficient mice suffer from severe intestinal and systemic inflammation and display aberrant innate and adaptive immune responses. In particular, PTPN2 is involved in the regulation of inflammatory signalling cascades, and critical for protecting intestinal epithelial barrier function, regulating innate and adaptive immune responses, and finally for maintaining intestinal homeostasis. On one hand, dysfunction of PTPN2 has drastic effects on innate host defence mechanisms, including increased secretion of pro-inflammatory cytokines, limited autophagosome formation in response to invading pathogens, and disruption of the intestinal epithelial barrier. On the other hand, PTPN2 function is crucial for controlling adaptive immune functions, by regulating T cell proliferation and differentiation as well as maintaining T cell tolerance. In this way, dysfunction of PTPN2 contributes to the manifestation of IBD. The aim of this review is to present an overview of recent findings on the role of PTPN2 in intestinal homeostasis and the impact of dysfunctional PTPN2 on intestinal inflammation. | Marianne R Spalinger Declan F McCole Gerhard Rogler Michael Scharl | 2016 | World Journal of Gastroenterology2016，22，3： | 4 |
| 6 | Efficacy of telemedicine on glycaemic control in patients with type 2 diabetes:A meta-analysis显示文摘BACKGROUND Telemedicine is defined as the delivery of health services via remote communication and technology.It is a convenient and cost-effective method of intervention,which has shown to be successful in improving glyceamic control for type 2 diabetes patients.The utility of a successful diabetes intervention is vital to reduce disease complications,hospital admissions and associated economic costs.AIM To evaluate the effects of telemedicine interventions on hemoglobin A1c(HbA1c),systolic blood pressure(SBP),diastolic blood pressure(DBP),body mass index(BMI),post-prandial glucose(PPG),fasting plasma glucose(FPG),weight,cholesterol,mental and physical quality of life(QoL)in patients with type 2 diabetes.The secondary aim of this study is to determine the effect of the following subgroups on HbA1c post-telemedicine intervention;telemedicine characteristics,patient characteristics and self-care outcomes.METHODS PubMed Central,Cochrane Library,Embase and Scopus databases were searched from inception until 18th of June 2020.The quality of the 43 included studies were assessed using the PEDro scale,and the random effects model was used to estimate outcomes and I2 for heterogeneity testing.The mean difference and standard deviation data were extracted for analysis.RESULTS We found a significant reduction in HbA1c[-0.486%;95%confidence interval(CI)-0.561 to-0.410,P<0.001],DBP(-0.875 mmHg;95%CI-1.429 to-0.321,P<0.01),PPG(-1.458 mmol/L;95%CI-2.648 to-0.268,P<0.01),FPG(-0.577 mmol/L;95%CI-0.710 to-0.443,P<0.001),weight(-0.243 kg;95%CI-0.442 to-0.045,P<0.05),BMI(-0.304;95%CI-0.563 to-0.045,P<0.05),mental QoL(2.210;95%CI 0.053 to 4.367,P<0.05)and physical QoL(-1.312;95%CI 0.545 to 2.080,P<0.001)for patients following telemedicine interventions in comparison to control groups.The results of the meta-analysis did not show any significant reductions in SBP and cholesterol in the telemedicine interventions compared to the control groups.The telemedicine characteristic subgroup analysis revealed that clinical treatment models of intervention,as well as those involving telemonitoring,and those provided via modes of videoconference or interactive telephone had the greatest effect on HbA1c reduction.In addition,interventions delivered at a less than weekly frequency,as well as those given for a duration of 6 mo,and those lead by allied health resulted in better HbA1c outcomes.Furthermore,interventions with a focus on biomedical parameters,as well as those with an engagement level>70%and those with a drop-out rate of 10%-19.9%showed greatest HbA1c reduction.The patient characteristics investigation reported that Hispanic patients with T2DM had a greater HbA1c reduction post telemedicine intervention.For self-care outcomes,telemedicine interventions that resulted in higher postintervention glucose monitoring and self-efficacy were shown to have better HbA1c reduction.CONCLUSION The findings indicate that telemedicine is effective for improving HbA1c and thus,glycemic control in patients with type 2 diabetes.In addition,telemedicine interventions were also found to significantly improved other health outcomes as well as QoL scores.The results of the subgroup analysis emphasized that interventions in the form of telemonitoring,via a clinical treatment model and with a focus on biomedical parameters,delivered at a less than weekly frequency and 6 mo duration would have the largest effect on HbA1c reduction.This is in addition to being led by allied health,through modes such as video conference and interactive telephone,with an intervention engagement level>70%and a drop-out rate between 10%-19.9%.Due to the high heterogeneity of included studies and limitations,further studies with a larger sample size is needed to confirm our findings. | Julia De Groot Dongjun Wu Declan Flynn Dylan Robertson Gary Grant Jing Sun | 2021 | World Journal of Diabetes2021，12，2： | 3 |
| 7 | 临坡条形基础下地基极限承载力多因素影响规律的数值分析显示文摘为了系统分析边坡对临坡基础极限承载力的影响,采用控制变量法和FLAC3D有限差分软件,分别针对不同坡顶距、坡角、相对密实度、基底宽度的荷载-位移曲线,研究了极限承载力、极限承载力弱化系数、极限承载力系数的多因素演化规律。结果表明:极限承载力、极限承载力弱化系数、极限承载力系数随坡顶距增加而增大,当坡顶距b与基底宽度B之比大于5时增长趋于停滞,但未达到平地地基数值;地基极限承载力、弱化系数随坡角增加近似线性减小,变化速率基本不受坡顶距的影响;地基极限承载力、极限承载力系数随砂土相对密实度增加而增大,同时受到坡顶距的影响,大坡顶距下随相对密实度的变化速率高于小坡顶距;地基极限承载力受基底宽度的影响程度小于坡顶距,随基底宽度增加小幅度增大,极限承载力系数随基底宽度的增大而减小;地基极限承载力弱化系数对相对密实度、基底宽度不敏感;减小坡角、提高相对密实度与增大坡顶距对极限承载力的提高有类似的效果,单纯通过增大坡顶距仍不能达到接近平地极限承载力的水平,适当地减小坡角、增加相对密实度可增大接近平地地基极限承载力的可能性。研究结果可为临坡工程施工方案选择提供借鉴,对推动临坡地基的工程定量计算具有重要作用。 | 李震 默杨 任连伟 刘尚各 PHILLIPS Declan | 2018 | 水利水电技术2018，49，7： | 2 |
| 8 | Genomic organisation and allelic diversity within coding and non-coding regions of the Ovar-DRB1 locus显示文摘 | Keith T. Ballingall Kathleen Fardoe Declan J. McKeever | 2008 | Immunogenetics2008，，2： | 1 |
| 9 | Data sharing:the next generation显示文摘 | Declan Butler | 2007 | NATURE2007，446，： | 1 |
| 10 | Improved resolution methods for (R,R)-and (S,S)-cyclohexane-1,2-diamine and (R)-and (S)-BINOL显示文摘 | Hans-Jorg Schanz Michael A Linseis Declan G Gilheany | 2003 | Tetrahedron:Asymmetry2003，14，： | 1 |
| 11 | Valuing the Subsurface Pathogen Treatment Barrier in Water Recycling Via Aquifers for Drinking Supplies显示文摘 | Declan P Peter D Simon T | | 0，，06： | 1 |
| 12 | Occurrence and genetic analysis of picorna-like viruses infecting worker bees of Apis mellifera L. populations in Devon, South West England显示文摘 | Andrea Baker Declan Schroeder | 2008 | Journal of Invertebrate Pathology2008，，2： | 1 |
| 13 | HSP27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells显示文摘 | Gorman AM Szegezdi E Declan J | 2005 | Biochem Biophys Res Commun2005，327，： | 1 |
| 14 | A Phase II Dose Titration Study of Thalidomide for Cancer-Associated Anorexia显示文摘 | Mellar Davis Wael Lasheen Declan Walsh Fade Mahmoud Leslie Bicanovsky Ruth Lagman | 2012 | Journal of Pain and Symptom Management2012，，1： | 1 |
| 15 | Recent advance in the understanding of fibrous filter beheaver under solid particle load 显示文摘 | DECLAN C WALSH | 1996 | Filtration and Separation1996，，7： | 1 |
| 16 | A crop model cross calibration for use in regional climate impacts studies 显示文摘 | Wei Xiong Ian Holmanc Declan Conway | 2008 | Ecological Modelling2008，213，4： | 1 |
| 17 | Long-term rectal administration of high-dose Sus- tained-release morphine tablets 显示文摘 | Declan W Pamela S | 2002 | Supportive Care in Cancer2002，10，8： | 1 |
| 18 | Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an Adult Autism Spectrum Disorder Diagnostic Clinic显示文摘 | C. Ellie Wilson Nicola Gillan Deborah Spain Dene Robertson Gedeon Roberts Clodagh M. Murphy Stefanos Maltezos Janneke Zinkstok Katie Johnston Christina Dardani Chris Ohlsen P. Quinton Deeley Michael Craig Maria A. Mendez Francesca Happé Declan G. M. Murph | 2013 | Journal of Autism and Developmental Disorders2013，，11： | 1 |
| 19 | Errors in Opioid Prescribing: A Prospective Survey in Cancer Pain显示文摘 | Philip E. Shaheen Susan B. LeGrand Declan Walsh Bassam Estfan Mellar P. Davis Ruth L. Lagman Mohammad Riaz Bushra Cheema | 2010 | Journal of Pain and Symptom Management2010，，4： | 1 |
| 20 | TGF-beta1-induced EMT can occur independently of its proapop-totic effects and is aided by EGF receptor activation显示文摘 | NEIL GD ORFHLAITH ES DECLAN AH | 2006 | Am J Physiol Renal Physiol2006，290，5： | 1 |
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