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    题名 作者 年代 出处 被引量
1Regulating the stability of TGFβ receptors and Smads显示文摘转变生长因素尾(TGF 尾) 在胚胎、成年的纸巾控制细胞的行为。对血浆膜上的 serine/threonine kinase 受体有约束力的 TGF 尾激活 Smad 分子和另外的发信号蛋白质一起调整基因表示。在瞄准 TGF 下游地解释在发信号的网络的几个部件之间的协作的这评论,机制和模型,尾被介绍。我们讨论 TGF 尾 receptor/Smad 发信号的活动和持续时间怎么能被在小径影响关键蛋白质的稳定性的 translational 以后修正调整。我们加亮在这些机制和人的疾病之间的连接,例如组织纤维变性和癌症。Peter Lonn Anita Moren Erna Raja Markus Dahl Aristidis Moustakas 2009Cell Research2009,19,1:39
2Evaluation of acoustic radiation force impulse imaging for determination of liver stiffness using transient elastography as a reference显示文摘AIM: To evaluate cut-off values and performance of acoustic radiation force impulse imaging (ARFI) using transient elastography [FibroScan■ (FS)] as a reference. METHODS: Six hundred and six patients were enrolled in this study.All patients underwent liver stiffness measurement with FS (FS-LS) and ARFI (with shear wave velocity quantification; ARFI-SWV) and the performance of ARFI in comparison to FS was determined. Sixtyeight patients underwent liver biopsy. RESULTS: Significantly higher success rates for the determination of liver stiffness were found using ARFI as compared to FS [604/606 (99.7%) vs 482/606 (79.5%); P < 0.001]. ARFI-SWV correlated significantly with FS-LS (r = 0.920, P < 0.001). ARFI-SWV increased significantly with the stage of fibrosis (1.09 ± 0.13 m/s for patients with no significant fibrosis (FS-LS < 7.6 kPa); 1.46 ± 0.27 m/s for patients with significant liver fibrosis (7.6 < FS-LS ≤ 13.0 kPa); and 2.55 ± 0.77 m/s for patients with liver cirrhosis (FS-LS > 13.0 kPa)). ARFI-SWV cut-off values were identified for no significant fibrosis (1.29 m/s; sensitivity 91.4% and specificity 92.6%) and for liver cirrhosis (1.60 m/s; sensitivity 92.3% and specificity 96.5%). The optimal cut-off value for predicting liver fibrosis (F ≥ 2) was 1.32 m/s (sensitivity 87.0% and specificity 80.0%) and for liver cirrhosis (F4) 1.62 m/s (sensitivity 100% and specificity 85.7%), for patients who underwent liver biopsy. An excellent inter-and intraobserver reproducibility was observed for ARFI-SWV determinations. CONCLUSION: An ARFI-SWV cut-off value of 1.29 m/s seems to be optimal for patients with no significant liver fibrosis and 1.60 m/s for patients with liver cirrhosis.Gerald Kircheis Abdurrahman Sagir Christoph Vogt Stephan vom Dahl Ralf Kubitz Dieter Hussinger 2012World Journal of Gastroenterology2012,18,10:30
3Self-Assembly and Photocatalysis of Mesoporous TiO2 Nanocrystal Clusters显示文摘有大表面区域和提高的 photocatalytic 活动的锐钛矿 TiO2 的 Mesoporous nanocrystal 簇成功地被综合了。合成包含进亚微米簇,有硅石层的这些簇的涂层,移开器官的 ligands 并且改进簇的 crystallinity 的热处理,和暴露 mesoporous 催化剂的最后搬迁的硅石的恐水病的 TiO2 nanocrystals 自己组装。在硅石涂层的帮助下,簇不仅维持他们的小谷物尺寸而且在高温度在锻烧以后保留他们的 mesoporous 结构(与象 277 m2/g 一样高的赌注表面区域) 。蚀刻 SiO2 也导致在水里有高 dispersity 的簇。我们能识别最佳的锻烧温度生产拥有高 crystallinity 和大表面区域的 TiO2 nanocrystal 簇,因此由紫外光在照明下面在器官的分子的分解显示出优秀催化效率。与氮的方便的做在可见的光和自然日光把这些 nanocrystal 簇变换成活跃光催化剂。用 nanocrystals 形成明确的 mesoporous 簇的策略为与提高的活动和稳定性设计光催化剂答应一个万用、有用的方法。Qiao Zhang Ji-Bong Joo Zhenda Lu Michael Dahl Diana Q. L. Oliveira Miaomiao Ye Yadong Yin 2011Nano Research2011,4,1:17
4城市空间与交通——哥本哈根的策略与实践显示文摘简要介绍了哥本哈根通过优先可持续的交通模式,充分发挥骑车和步行给都市生活带来的积极效果,以及制订的一系列城市空间发展策略和这些策略提出的背景,并通过个案分析展示了这些策略是如何通过试验和公众参与而得到执行的。Jesper Dahl 李华东 王晓京 2011建筑学报2011,,1:10
5Animal models of pancreatitis: Can it be translated to human pain study?显示文摘Chronic pancreatitis affects many individuals around the world,and the study of the underlying mechanisms leading to better treatment possibilities are important tasks.Therefore,animal models are needed to illustrate the basic study of pancreatitis.Recently,animal models of acute and chronic pancreatitis have been thoroughly reviewed,but few reviews address the important aspect on the translation of animal studies to human studies.It is well known that pancreatitis is associated with epigastric pain,but the understanding regarding to mechanisms and appropriate treatment of this pain is still unclear.Using animal models to study pancreatitis associated visceral pain is difficult,however,these types of models are a unique way to reveal the mechanisms behind pancreatitis associated visceral pain.In this review,the animal models of acute,chronic and un-common pancreatitis are briefly outlined and animal models related to pancreatitis associated visceral pain are also addressed.Jing-Bo Zhao Dong-Hua Liao Thomas Dahl Nissen 2013World Journal of Gastroenterology2013,19,42:6
6高地应力岩体特殊照明峒室围岩支护设计显示文摘为特殊照明和交通安全在世界最长的双峒公路隧道——秦岭终南山隧道内设计了6个峒室,该隧道穿越中国陕西省秦岭山脉,最大埋深达1 800 m。在峒址附近的2个位置采用应力解除法量测岩石地应力,该处的岩石覆盖厚度分别为1 600和400 m,量测结果显示极高的地应力。为满足照明和行车安全的要求,每个峒室设计成纺锤型,长度为200 m,最大宽度为22 m。受到已建成隧道的限制,两峒室间最小岩柱厚度只有8 m。峒室的主要特征为:(1)高地应力;(2)岩石条件较好;(3)与峒室尺寸相比岩柱厚度很小,这些特征对围岩支护提出极大的挑战。围岩支护是依据岩体分类Q系统采用经验法设计,然后采用数值分析校核。临时支护和永久支护系统均采用喷射混凝土和锚杆。为保证施工和运行期的峒室稳定提出一整套实施程序,包括开挖、喷射混凝土、安装锚杆和监控措施。对于极高地应力区域的峒室采用柔性支护,允许岩体在永久支护安装前发生部分变形,从而保证峒室稳定及支护元件安全可靠地发挥效用。分别采用FLAC3D和Phase 2程序进行三维和二维数值分析,三维计算主要用于研究峒室的整体稳定及沿隧道轴向的三维效应;二维计算用于详细研究施工顺序和各支护单元的功效。数值分析显示喷射混凝土和锚杆在各施工阶段都能安全运作,从而验证了围岩支护设计。吕明 GRφV E DAHLE H 乔怀玉 文邦后 陈忠明 赵秋林 2008岩石力学与工程学报2008,27,1:4
7Meta‐analysis: the safety and efficacy of vaptans (tolvaptan, satavaptan and lixivaptan) in cirrhosis with ascites or hyponatraemia显示文摘E. Dahl L. L. Gluud N. Kimer A. Krag 2012Aliment Pharmacol Ther2012,,7:3
8ESPEN Guidelines on Enteral Nutrition: Liver disease显示文摘M. Plauth E. Cabré O. Riggio M. Assis-Camilo M. Pirlich J. Kondrup P. Ferenci E. Holm S. vom Dahl M.J. Müller W. Nolte 2006Clinical Nutrition2006,,2:3
9Further extension of the opine concept: Plasmids in Agrobacterium rhizogenes cooperate for opine degradation显示文摘Annik Petit Chantal David Gary A. Dahl Jeffrey G. Ellis Pierre Guyon Francine Casse-Delbart Jacques Tempé 1983MGG Molecular & General Genetics1983,,2:3
10The role of solute in grain refinement of magnesium显示文摘Y. C. Lee A. K. Dahle D. H. StJohn 2000Metallurgical and Materials Transactions A2000,,11:3
11生态博物馆原则:专业博物馆学者和当地居民的共同参与显示文摘陶维·达儿(Torveig Dahl) 张晋平(译) 2005中国博物馆2005,,3:3
12Development and predictive validity of the cirrhosis-associated ascites symptom scale: A cohort study of 103 patients显示文摘AIM To develop a scale of domains associated with the health-related quality-of-life(HRQOL) in patients with cirrhosis-related ascites.METHODS We initially undertook literature searches and a qualitative study in order to design a cirrhosis-associated ascites symptom(CAS) scale describing symptoms with a potential detrimental impact on health related quality of life(HRQL)(the higher the score, the worse the symptoms). Discriminatory validity was assessed in a validation cohort including cirrhotic patients with(1) tense/severe;(2) moderate/mild; or(3) no ascites(controls). Patients also completed chronic liver disease questionnaire(CLDQ) and the Euro QoL 5-Dimensions 5-Level(EQ-5D-5L) questionnaire evaluating HRQL. The relation between scale scores was analysed using Spearman correlations. RESULTS The final CAS scale included 14 items. The equivalent reliability was high(Chronbach's alpha 0.88). The validation cohort included 103 patients(72% men, mean age 62.4 years). The mean scores for each question in the CAS scale were higher for patients with severe/tense ascites than for mild/moderate ascites and controls. Compared with controls(mean = 9.9 points), the total CAS scale score was higher for severe/tense ascites(mean = 23.8 points) as well as moderate/mild ascites(mean = 18.6 points)(P < 0.001 both groups). We found a strong correlation between the total CAS and CLDQ score(rho = 0.82, P < 0.001) and a moderate correlation between the CAS and the EQ-5D-5L score(0.67, P < 0.001). CONCLUSION The CAS is a valid tool, which reflects HRQOL in patients with ascites.Agnete Nordheim Riedel Nina Kimer Anne-Sofie Houlberg Jensen Emilie Kristine Dahl Mads Israelsen Luise Aamann Lise Lotte Gluud 2018World Journal of Gastroenterology2018,24,15:3
13生物防治的前景——由细菌杀蚴剂到藻类显示文摘广义上的生物防治与防治水生双翅目,主要是指蚊虫的防治物,如捕食者、寄生性线虫已有专门的综述,苏云金杆菌与球形芽孢杆菌的成功使用与其毒性特征以及蚊库、按蚊的饲食方式有关。使用细菌或原虫及藻类、真菌的可能性现被讨论。推荐具有生物防治的综合防治作为一些敏感地区长期使用与可行的方法。在长期的经济核算中如果包括环境污染的消耗,那使用生物防治则是更为安全与经济的方法。Christine Dahl 薛瑞德 1993医学动物防制1993,9,3:2
14Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli显示文摘Kristin V. T. Engebretsen Ida G. Lunde Mari E. Strand Anne Waehre Ivar Sjaastad Henriette S. Marstein Biljana Skrbic Christen P. Dahl Erik T. Askevold Geir Christensen Johannes L. Bj?rnstad Theis T?nnessen 2013FEBS J2013,,10:2
15幼鼠Sertoli细胞分泌一种刺激Leydig细胞合成雄激素的因子显示文摘本文利用幼鼠Sertoli和Leydig细胞单独或一起培养的方法研究了Sertoli细胞对Leydig细胞的局部影响。结果发现:(1)FSH和LH都能刺激胚胎和幼鼠的睾丸细胞雄激素的生物合成,最大的刺激作用是在生后3—5天;(2)幼鼠Sertoli细胞在FSH作用下分泌一种(些)物质,它能直接(只在幼龄期)或与LH协同刺激Leydig细胞雄激素的合成;(3)Sertoli刺激因子不是类固醇或其他小分子化合物,可能是一种热不稳定的多肽。这种因子可能对幼鼠Leydig细胞向成鼠Leydig细胞的分化和激素合成能力的转化过程中起重要作用。刘以训 K. D. Dahl 1989中国科学(B辑)1989,,3:2
16Pilot Study of Sentinel-Node-Based Adoptive Immunotherapy in Advanced Colorectal Cancer显示文摘Mona Karlsson PhD Per Marits PhD Kjell Dahl PhD Tobias Dag?? MD Sven Enerb?ck Magnus Th?rn Ola Winqvist 2010Annals of Surgical Oncology2010,,7:2
17Mechanisms of acetaldehyde mediated growth inhibition: delayed cell cycle progression and induction of apoptosis显示文摘Zimmerman BT Crawford GD Dahl R 1995Alcohol-clin-exp-res1995,19,2:2
18Hepatic encephalopathy as a complication of liver disease显示文摘INTRODUCTIONHepatic encephalopathy ( HE) is a frequent complication of chronic liver disease .It is defined as a characteristic functional and reversible alteration of the mental state ,due to impaired liver function and / or increased portosystemic shunting .Stephan vom Dahl Gerald Kircheis Dieter Haussinger 2001World Journal of Gastroenterology2001,7,2:2
19Pre-emptive analgesia显示文摘 rgen B. Dahl Steen iniche 2004British Medical Bulletin2004,,:2
20The Nature of Self-Reported Guilt in Consumption Contexts显示文摘Darren W. Dahl Heather Honea Rajesh V. Manchanda 2003Marketing Letters2003,,3:2
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