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| 1 | 睾酮和代谢综合症显示文摘关于代谢综合症的诊断价值始终存在争议。很多代谢综合症的相关因素亦被认定为心血管疾病的风险因素。尽管代谢综合征的诊断标准包括胰岛素抵抗,但其发生率并不普遍。伴有肥胖和腰围增大的高胰岛素血症及高炎症因子状态可以很好的解释代谢综合症患者的低睾酮和低性激素结合蛋白(SHBG)水平。低SHBG水平可以预测代谢综合症的发病率;低睾酮水平是心血管疾病的风险因素,但不一定是发病因素。国际糖尿病学会推荐的治疗代谢综合症的策略包括心血管风险评估、生活方式及饮食习惯的改善、锻炼、控制体重、以及个体性风险因素的控制等。然而,代谢综合症患者很少可以有效控制自己的体重。近来,有研宄发现睾酮补充可以减轻体重、减少腰围、胰岛素增敏、改善血红蛋白A1c水平,甚至改善代谢综合症的所有发病因素。同时,也有一些观察性研究结果显示睾酮补充会导致心血管事件发生率升高,对此FDA进行了详细追踪,结果显示此类报道有侍商椎。目前,大样本随机对照研究亟待开展,用以验证睾酮补充疗法治疗伴有睾酮水平低下的中老年代谢综合症患者的安全性及有效性。 | Glenn R Cunningham | 2015 | Asian Journal of Andrology2015，17，2： | 9 |
| 2 | Long-Term Outcomes for Patients with Post–Liver Transplant Anastomotic Biliary Strictures Treated by Endoscopic Stent Placement显示文摘 | Joseph Morelli Hugh E Mulcahy Ira R Willner John T Cunningham Peter Draganov | 2003 | Gastrointestinal Endoscopy2003，，3： | 2 |
| 3 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study显示文摘 | Julia Granerod Helen E Ambrose Nicholas WS Davies Jonathan P Clewley Amanda L Walsh Dilys Morgan Richard Cunningham Mark Zuckerman Ken J Mutton Tom Solomon Katherine N Ward Michael PT Lunn Sarosh R Irani Angela Vincent David WG Brown Natasha S Crowcroft | 2010 | The Lancet Infectious Diseases2010，，12： | 2 |
| 4 | Signaling pathway activated during apoptosis of the proSTATe cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for proSTATe cancer显示文摘 | Marcelli M Cunningham G R Walkup M | 1999 | Cancer Res1999，59，2： | 1 |
| 5 | A System for Ex- tracting Three-Dimensional Measurements {rom a Stereo Pair of TV Cameras显示文摘 | Yakimovsky Y Cunningham R | 1978 | Computer Graphics and Image Processing1978，7，2： | 1 |
| 6 | Phytoremediation of contaminated soils显示文摘 | Cunningham S D Berti W R Huang J W | 1995 | Trends in Biotechnology1995，13，9： | 1 |
| 7 | Phytoremediation of contaminated soils显示文摘 | Cunningham S D Berti W R Huang J W | 1995 | Trends in Biotechnology1995，13，9： | 1 |
| 8 | The case for plain packaging 显示文摘 | Cunningham R Kyle K | 1995 | Tob Control1995，4，： | 1 |
| 9 | Randomized trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer显示文摘 | Cunningham D Pyrhonen S James R D | 1998 | Lancet1998，352，： | 1 |
| 10 | Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats 显示文摘 | Sanchez-Pemaute R Harvey-White J Cunningham J | 2001 | Mol Ther2001，4，4： | 1 |
| 11 | Effect on MRSA transmission of rapid PCR testing of patients admitted to critical care显示文摘 | Cunningham R Jenks P Northwood J Wallis M Ferguson S Hunt S | | Journal of Hospital Infection0，，： | 1 |
| 12 | Three-dimensional seismic geomorphology of a deep-water slope-channel system:the Sequoia field, offshore west Nile Delta, Egypt显示文摘 | Cross N E Cunningham A Cook R J | 2008 | AAPG Bulletin2008，92，8： | 1 |
| 13 | Seasonal ice area and volume production of the Arctic Ocean: November 1996 through April 1997显示文摘 | Kwok R F Cunningham G | 2002 | Journal of Geo- physical Research Oceans2002，107，10： | 1 |
| 14 | The importance of cadmium as a factor in calcified upper urinary tract stone disease- A prospective 7-year study 显示文摘 | Scott R Cunningham C Lelland | 1982 | Br J Urol1982，54，6： | 1 |
| 15 | Three-dimen-sional seismic geomorphology of a deep-water slope-channelsystem:The Sequoia field,offshore west Nile Delta,Egypt显示文摘 | Cross N E Cunningham A Cook R J | 2009 | AAPG Bulletin2009，93，： | 1 |
| 16 | On the recursive sequence xn+1=(α-βxn)/(Bxn+Cxn-1)显示文摘 | Cunningham K C Kulenovic M R S Ladas G | 2001 | Nonlinear Analysis TMA2001，47，： | 1 |
| 17 | 'Macrochip' com- puter systems enabled by silicon photonic interconnects 显示文摘 | Raj K Cunningham J E Ho R | 2010 | Proceedings of SPIE2010，7607，： | 1 |
| 18 | Infections associated with haemophagocytic syndrome 显示文摘 | Rouphael NG Talati NJ Vaughan C Cunningham K Moreira R Gould C | 2007 | Lancet Infect Dis2007，7，12： | 1 |
| 19 | Roles for laminin in embryogenesis:exencephaly,syndactyly,and plaeentopathy in mice lacking the laminin alpha 5 chain显示文摘 | Miner J H Cunningham J Sanes J R | 1998 | J Cell Biol1998，14，： | 1 |
| 20 | Dynamic variable speed limit strategies for real-time crashrisk reduction on freeways显示文摘 | ABDEL-AT Y M CUNNINGHAM R J GAY AH V V | 2008 | Transportation Research RecordJournal of the Transportation Reseach Board2008，，2078： | 1 |
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