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| 1 | HIDA scan for functional gallbladder disorder: ensure that you know how the scan was done显示文摘BACKGROUND: Despite the increasing use of fatty meal(FM) as a substitute for cholecystokinin(CCK) in pain reproduction during hepato-imino-diacetic acid(HIDA) scan in functional gallbladder disorder, there are no studies comparing the differences between CCK and FM. The present study was to compare the efficacy of FM in comparison of CCK in FGBD application. METHODS: Patients undergoing HIDA scans from August 2013 to May 2014 were divided into two groups: those undergoing CCK-stimulated HIDA scan versus FM-stimulated HIDA scan. These groups were compared according to demographics and HIDA results.RESULTS: Of 153 patients, 70 received CCK and 83 FM. There was no difference regarding age, gender, gallstones, gallbladder ejection fraction and time to visualization. However, significantly more of the patients receiving CCK than FM experienced pain reproduction(61% vs 30%, P<0.01).CONCLUSIONS: Stimulation of gallbladder contractility with a FM during HIDA is less than half as likely to reproduce biliary symptoms compared to CCK, despite similar ejection fractions and other parameters. It is essential that providers account for this difference when counseling patients regarding cholecystectomy for functional gallbladder disorder. | Naeem Goussous Hadia Maqsood Ethan Spiegler Gopal C Kowdley Steven C Cunningham | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，2： | 5 |
| 2 | Production of citric and oxalic acids and solubilization of calcium phosphate by Penicillium biaii显示文摘 | Cunningham J E and Kuiacy C | 1992 | Appl Env- iron Micro1992，58，5： | 3 |
| 3 | Differentiating intraductal papillary mucinous neoplasms from other pancreatic cystic lesions显示文摘Intraductal papillary mucinous neoplasms(IPMN) can be difficult to distinguish from other cystic lesions of the pancreas.To understand better and discuss the current knowledge on this topic,the literature and the institutional experience at a large pancreatic disease center have been reviewed.A combination of preoperative demographic,historical,radiographic,laboratory data,as well as postoperative pathologic analyses can often distinguish IPMN from other lesions in the differential diagnosis. | Steven C Cunningham Ralph H Hruban Richard D Schulick | 2010 | World Journal of Gastrointestinal Surgery2010，2，10： | 3 |
| 4 | The “Colonial Wig” pancreaticojejunostomy:zero leaks with a novel technique for reconstruction after pancreaticoduodenectomy显示文摘BACKGROUND: Postoperative pancreatic fistula(POPF) remains common and morbid after pancreaticoduodenectomy(PD). A major advance in the study of POPF is the fistula risk score(FRS).METHODS: We analyzed 48 consecutive patients undergoing PD. The 'Colonial Wig' pancreaticojejunostomy(CWPJ) technique was used in the last 22 PDs, we compared 22 CWPJ to 26 conventional PDs. RESULTS: Postoperative morbidity was 49%(27% Clavien grade >2). The median length of hospital stay was 11 days. In the first 26 PDs, the PJ was performed according to standard techniques and the clinically relevant POPF(CR-POPF) rate was 15%, similar to the FRS-predicted rate(14%). In the next 22 PJs, the CWPJ was employed. Although the FRS-predicted rates were similar in these two groups(14% vs 13%), the CRPOPF rate in the CWPJ group was 0(P=0.052).CONCLUSION: Early experience with the CWPJ is encouraging, and this anastomosis may be a safe and effective way to lower POPF rates. | Xihua Yang Pouya Aghajafari Naeem Goussous Shirali T Patel Steven C Cunningham | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，5： | 2 |
| 5 | Minimally invasive and open gallbladder cancer resections: 30-vs 90-day mortality显示文摘BACKGROUND:Minimally invasive surgery is increasingly used for gallbladder cancer resection.Postoperative mortality at 30 days is low,but 90-day mortality is underreported.METHODS:Using National Cancer Database(1998-2012),all resection patients were included.Thirty-and 90-day mortality rates were compared.RESULTS:A total of 36 067 patients were identified,19 139(53%) of whom underwent resection.Median age was 71 years and 70.7% were female.Ninety-day mortality following surgical resection was 2.3-fold higher than 30-mortality(17.1% vs 7.4%).There was a statistically significant increase in 30-and 90-day mortality with poorly differentiated tumors,presence of lymphovascular invasion,tumor stage,incomplete surgical resection and low-volume centers(P<0.001 for all).Even for the 1885 patients who underwent minimally invasive resection between 2010 and 2012,the 90-day mortality was 2.8-fold higher than the 30-day mortality(12.0% vs 4.3%).CONCLUSIONS:Ninety-day mortality following gallbladder cancer resection is significantly higher than 30-day mortality.Postoperative mortality is associated with tumor grade,lymphovascular invasion,tumor stage,type and completeness of surgical resection as well as type and volume of facility. | Naeem Goussous Motahar Hosseini Anne M Sill Steven C Cunningham | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，4： | 2 |
| 6 | Pancreatic duct disruption and nonoperative management: the SEALANTS approach显示文摘Pancreatic-duct disruption (PDD) can be difficult to manage, with diverse etiologies and sequelae in a heterogeneous population. Common etiologies include pancreatitis, iatrogenic injury, and trauma. Sequelae of PDD include pseudocyst, pancreatic ascites, | Alain Abdo Niraj Jani Steven C Cunningham | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，3： | 2 |
| 7 | Primary immunodeficiencies : 2009 update 显示文摘 | Chapel H Conley ME Cunningham -Rundles C | 2009 | Allergy Clin lmmunol2009，124，6： | 1 |
| 8 | Systemic infections and inflammation affect chronic neurodegeneration显示文摘 | Perry VH Cunningham C Holmes C | 2007 | Nat Rev Immunol2007，7，： | 1 |
| 9 | Report of two protocol planned interim analyses in a randomised multicentre phase III study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric cancer receiving ECF显示文摘 | Sumpter K Harper-Wynne C Cunningham D | 2005 | British Journal of Cancer2005，92，11： | 1 |
| 10 | Tibial externa fixation, weight hearing and fracture movement 显示文摘 | Kershaw C J Cunningham JL Kenwright J | 1993 | Cli Orthop1993，293，： | 1 |
| 11 | Biomechanical comparision of five different atlantoaxial posterior fixation techniques显示文摘 | Henriques T Cunningham BW Olerud C | 2000 | Spine2000，25，22： | 1 |
| 12 | In vitro biomeehanical investigation of the stability and stress shielding effect of lumbar interbody fu- sion deviees显示文摘 | Kanayama M Cunningham B W Haggerty C J Abumi K Kaneda K McAfee P C | 2000 | J Neurosurg2000，93，2： | 1 |
| 13 | Phase I and pharmacokinetic study of the dolastatin-15 ana-logue tasidotin (ILX651 ) administered intravenously on days 1,3,and 5 every 3 weeks in patients with advanced solid tumors 显示文摘 | CUNNINGHAM C APPLEMAN L J KIRVAN-VISOVATTI M | 2005 | Clin Cancer Res2005，11，21： | 1 |
| 14 | Biomechanical analysis of rotationaI motions after disc arthroplasty:implications for patients with adult deformities显示文摘 | McAfee P C Cunningham B W Hayes V Sidiqi F Dabbah M Sefter J C | 2006 | Spine2006，31，19： | 1 |
| 15 | Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea,anomura)显示文摘 | Hickerson M J Cunningham C W | 2000 | Molecular Biology and Evolution2000，17，4： | 1 |
| 16 | The effect of nitric oxide donors on insulin secretion,cyclic GMP and cyclic AMP inratislets of Langerhansand the nsulin-secreting cell lines HIT-T15 and RINm5F显示文摘 | Cunningham J M Mabley J G Delaney C A | 1994 | Mol Cell Endocrinol1994，102，12： | 1 |
| 17 | Technology opportunities analysis:integrating technology monitoring, forecasting and assessment with strategic planning显示文摘 | Porter A L Jin X-Y Gilmour J E Cunningham S W Xu H Stanard C WangL | 1994 | SRA Journal (Society of Research Administrators)1994，，2： | 1 |
| 18 | Development and use of a DNA probe for confirmation d cDNA from infectious salmon anaemia virus (ISAV) in PCR products显示文摘 | MCBEATH A J A BURR K L A CUNNINGHAM C O | 2000 | Bull Eur Fish Pathol2000，20，： | 1 |
| 19 | Nanodiamond bioconjugate probes and their collection by electrophoresis 显示文摘 | Hens S C Cunningham G Tyler T | 2008 | Diamond Relat Mater2008，17，11： | 1 |
| 20 | Inside the crossequalization black box显示文摘 | Ross C P Cunningham G B Weber D P | | 0，，： | 1 |
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