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| 1 | Intrinsic apoptotic pathway and G2/M cell cycle arrest involved in tubeimoside I-induced EC109 cell death显示文摘Objective: Squamous esophageal carcinoma is highly prevalent in developing countries, especially in China. Tu Bei Mu (TBM), a traditional folk medicine, has been used to treat esophageal squamous cell carcinoma (ESCC) for a long term. tubeimoside I (TBMS1) is the main component of TBM, exhibiting great anticancer potential. In this study, we investigated the mechanism of TBMS1 cytotoxic effect on EC109 cells. Methods: Comparative nuclear proteomic approach was applied in the current study and we identified several altered protein spots. Further biochemical studies were carried out to detect the mitochondrial membrane potential, cell cycle and corresponding proteins' expression and location. Results: Subcellular proteomic study in the nucleus from EC109 cells revealed that altered proteins were associated with mitochondrial function and cell proliferation. Further biochemical studies showed that TBMS1-induced molecular events were related to mitochondria-induced intrinsic apoptosis and P21-cyclin B1/cdc2 complex-related G2/M cell cycle arrest. Conclusions: Considering the conventional application of TBM in esophageal cancer, TBMS1 therefore may have a great potential as a chemotherapeutic drug candidate for ESCC. | Yang Xu Guanghui Wang Quancheng Chen Ting Lin Zhiping Zeng Qiang Luo Jie Liu Cuiling Sun | 2013 | Chinese Journal of Cancer Research2013，25，3： | 12 |
| 2 | Recent progress of composite solid polymer electrolytes for all-solid-state lithium metal batteries显示文摘In comparison with lithium-ion batteries(LIBs)with liquid electrolytes,all-solid-state lithium batteries(ASSLBs)have been considered as promising systems for future energy storage due to their safety and high energy density.As the pivotal component used in ASSLBs,composite solid polymer electrolytes(CSPEs),derived from the incorporation of inorganic fillers into solid polymer electrolytes(SPEs),exhibit higher ionic conductivity,better mechanical strength,and superior thermal/electrochemical stability compared to the single-component SPEs,which can significantly promote the electrochemical performance of ASSLBs.Herein,the recent advances of CSPEs applied in ASSLBs are presented.The effects of the category,morphology and concentration of inorganic fillers on the ionic conductivity,mechanical strength,electrochemical window,interfacial stability and possible Li+transfer mechanism of CSPEs will be systematically discussed.Finally,the challenges and perspectives are proposed for the future development of high-performance CSPEs and ASSLBs. | Qingjiang Yu Kecheng Jiang Cuiling Yu Xianjin Chen Chuanjian Zhang Yi Yao Bin Jiang Huijin Long | 2021 | Chinese Chemical Letters2021，32，9： | 4 |
| 3 | Statin therapy improves response to interferon alfa and ribavirin in chronic hepatitis C: A systematic review and meta-analysis显示文摘 | Qianqian Zhu Na Li Qunying Han Pingping Zhang Cuiling Yang Xiaoyan Zeng Yanping Chen Yi Lv Xi Liu Zhengwen Liu | 2013 | Antiviral Research2013，，3： | 3 |
| 4 | Preparation and characterization of graphite nanosheets from ultrasonic powdering technique显示文摘 | Guohua Chen Wengui Weng Dajun Wu Cuiling Wu Jinrong Lu Pingping Wang Xiangfeng Chen | 2004 | Carbon2004，，4： | 2 |
| 5 | Exfoliation of graphite flake and its nanocomposites显示文摘 | Guohua Chen Dajun Wu Wengui Weng Cuiling Wu | 2002 | Carbon2002，，3： | 1 |
| 6 | Study on the graphite nanosheets/resin shielding coating 显示文摘 | Wang Taosheng Chen Guohua Wu Cuiling | 2007 | Progress in Organic Coatings2007，59，3： | 1 |
| 7 | 3DRGO-NiFe2O4/NiO nanoparticles for fast and simple detection of organophosphorus pesticides显示文摘The residues of organophosphorus pesticide(OPs)on fruits and vegetables pose a threat to human health,so it is very meaningful to explore simple and fast detect methods for OPs residual.In this work,nickel ferrite/nickel oxide nanoparticles co-loaded three-dimensional reduced graphene oxide(3DRGONiFe2O4/NiO NPs),as a new low cost nanocomposite,was prepared.Based on its high performance mimetic peroxidase activity,a colorimetric method for the detection of OPs has been developed.Dichlorvos was chosen as model compounds to evaluate the detection performance.The detection linear range for dichlorvos is from 50μg/mL to 2.5×10^4μg/mL with a detection limit of 10μg/mL.Furthermore,a test paper can be developed based on the 3 DRGO-NiFe2O4/NiO NPs for visual detection of dichlorvos,and the image information of the paper sensor can be converted into digital signal and quantitative detection by a smartphone.Notably,this method can also be used to detect dichlorvos in real samples,including vegetables and fruits.Thus,the developed naked assay holds great potential in simple,inexpensive and rapid detection of OPs in fruit and vegetable samples. | Zhenni Wei Huiqing Li Jing Wu Yalei Dong Hongyi Zhang Hongli Chen Cuiling Ren | 2020 | Chinese Chemical Letters2020，31，1： | 1 |
| 8 | IL21 and IL21R polymorphisms and their interactive effects on serum IL-21 and IgE levels in patients with chronic hepatitis B virus infection显示文摘 | Na Li Qianqian Zhu Zhu Li Qunying Han Jinghong Chen Yi Lv Yawen Wang Xiaoyan Zeng Yanping Chen Cuiling Yang Zhengwen Liu | 2013 | Human Immunology2013，，： | 1 |
| 9 | Existence and construction of compactly suppoeted biorthogonal multiple vector-valued wavelets 显示文摘 | Chen Qingjiang Cheng Zhengxing Wang Cuiling | 2006 | Journal of Applied Mathematics and Computing2006，22，3： | 1 |
| 10 | Study on the graphite nanosheets/resin shielding coatings显示文摘 | Wang Taosheng Chen Guohua Wu Cuiling | 2007 | Progress Organic Coat2007，59，2： | 1 |
| 11 | 显示文摘 | Chen Guohua Wu Cuiling Weng Wengui | 2003 | Polymer2003，44，6： | 1 |
| 12 | Preparation of polystyrene/ graphite nanosheet composite 显示文摘 | Chen Guohua Wu Cuiling | 2003 | Polymer2003，44，6： | 1 |
| 13 | Preparation of polystyrene/graphite nanosheet composite显示文摘 | Cuiling Wu | 2003 | Polymer2003，44，： | 1 |
| 14 | Superior electrocatalytic activity of mesoporous Au film templated from diblock copolymer micelles显示文摘在极端大的毛孔附近由互连的 Au 系带的一个网络组成的 Mesoporous Au 电影被发现向懒惰反应展出一项有希望的 electrocatalytic 活动。有直到 25 nm 的毛孔尺寸的 Mesoporous Au 电影成功地用一条聚合 micelle 途径被制作。向甲醇氧化的 mesoporous Au 电影的一项优异催化活动被证实,它彻底地被分析并且与另外的 Au 材料的相比。在高催化的活动的内在的调查表明同样准备的 mesoporous Au 电影的优异表演在 Au 表面上与它在有使 \O 结晶得好的方面和几个步 / 纽结地点的 mesopores 附近的唯一的原子结构有关。这些调查结果橱窗为准备能在 electrocatalytic 应用被用作有希望的候选人的高度活跃的基于 Au 的催化剂的一个战略、可行的图案。 | Cuiling Lil Bo Jiang Hungru Chen Masataka Imura Liwen Sang Victor Malgras Yoshio Bando Tansir Ahamad Saad M. Atshehri Satoshi Tominaka Yusuke Yamauchi | 2016 | Nano Research2016，9，6： | 1 |
| 15 | Exfoliation of graphite flake and its nanocomposites显示文摘 | Guohua Chen Dajun Wu Wengui Weng Cuiling Wu | 2002 | Carbon2002，，3： | 1 |
| 16 | Preparation of polystyrene/graphite nanosheet composite显示文摘 | Guohua Chen Cuiling Wu Wengui Weng | 2003 | Polymer2003，44，16： | 1 |
| 17 | Preparation and characterization of graphite nanosheets from ultrasonic powdering technique显示文摘 | Guohua Chen Wengui Weng Dajun Wu Cuiling Wu Jinrong Lu Pingping Wang Xiangfeng Chen | 2004 | Carbon2004，，4： | 1 |
| 18 | Preparation of polystyrene/graphite nanosheet composite 显示文摘 | Chen Guohua Wu Cuiling Weng Wengui | 2003 | Polymer2003，44，： | 1 |
| 19 | Preparation of polystyrene/graphite nanosheet composite显示文摘 | Chen Guohua Wu Cuiling Weng Wengui | 2003 | Polymer2003，44，6： | 1 |
| 20 | Preparation of polystyrene/graphite nanosheet composite 显示文摘 | Chen Guohua Wu Cuiling Weng Wengui | 2003 | Polymer2003，44，6： | 1 |
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