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49篇 您的检索式:作者名="Copetti R"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Lung ultrasound in the diagnosis and follow-up of community-acquired pneu-monia: a prospective, multicenter, diagnostic accuracy study 显示文摘ReissigA Copetti R Mathis G 2012Chest2012,142,4:1
3Lung ultrasound in respiratory distress syndrome:a useful tool for early diagnosis显示文摘Copetti R Cattarossi L Macagno F 0,,:1
4Ultrasound diagnosis of pneumonia in children 显示文摘Copetti R CattarossiL 2008Radiol Med2008,113,2:1
5Finite element approximation to a contact problem for a nonlinea thermoviscoelastic beam显示文摘Copetti M I M Fernandez J R 2011J Math Anal Appl2011,383,:1
6Current role of emergency ultrasound of the chest显示文摘Reissig A Copetti R Kroegel C 2011Crit Care Med2011,39,4:1
7Radiation exposure early in life can be reduced by lung ultrasound显示文摘Cattarossi L Copetti R Poskurica B 0,,:1
8Lung ultrasound in the di- agnosis and follow-up of community-acquired pneumonia: a prospective, multicenter, diagnostic accuracy study 显示文摘Reissig A Copetti R Mathis G 2012Chest2012,142,4:1
9Sonographic interstitial syndrome: the sound of lung water 显示文摘Soldati G Copetti R Sher S 2009J Ultrasound Med2009,28,2:1
10The calpain system is involved in the constitutive regulation of beta-catenin signaling functions 显示文摘Benetti R Copetti T Dell'Orso S 2005J Biol Chem2005,280,22:1
11Chest sonography:a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome显示文摘Copetti R Soldati G Copetti P 2008Cardiovasc Ultrasound2008,6,:1
12Sonographic interstitial syndrome: the sound of lung water 显示文摘Soldati G Copetti R Sher S 2009J Ultrasound Med2009,28,2:1
13Early recognition of the 2009 pandemic influenza A ( H1N1 ) pneumonia by chest ultrasound 显示文摘Testa A Soldati G Copetti R 2012Crit Care2012,16,1:1
14Sonographic interstitial syndrome the sound of lung water显示文摘Soldati G Copetti R Sher S 2009Journal of Ultrasound in Medicine2009,28,2:1
15Easily reversible hypoxemia and hypotension induced by nimodipine显示文摘 Copetti R 2004Eur J Emerg Med2004,11,5:1
16Radiation exposure early in life can be reduced by lung ultrasound 显示文摘Cattarossi L Copetti R Poskurica B 2011Chest2011,139,3:1
17The 'double lung point': an ultrasound sign diag- nostic of transient tachypnea of the newborn 显示文摘Copetti R Cattarossi L 2007Neonatology2007,91,3:1
18Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute re- spiratory distress syndrome 显示文摘Copetti R Soldati G Copetti P 2008Cardiovasc Ultrasound2008,6,1:1
19Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratorydistress syndrorne 显示文摘Copetti R Soldati G Copetti P 2008Cardiovasc Ultra- sound2008,29,6:1
20Chest sonography : a useful tool to diffe- rentiate acute cardiogenic pulmonary edema from acute respiratory dis- tress syndrome 显示文摘Copetti R Soldati G Copetti P 2008Cardiovasc Ultrasound2008,6,:1
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