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17篇 您的检索式：作者名="Copetti P"

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		题名	作者	年代	出处	被引量
	1	一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.	Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P	2014	中华神经外科疾病研究杂志2014，13，5：	6
	2	High specificity of quantitative methylationspecific PCR analysis for MGMT promoter hypermethylation detection in gliomas显示文摘	Parrella P La Torre A Copetti M	2009	J Biomed Biotechnol2009，2009，53：	1
	3	Comparison between real-time quantitative PCR detection of HER2 mRNA copy number in periph- eral blood and ELISA of serum HER2 protein for determining HER2 status in breast cancer patients 显示文摘	Strati A Parrella P Copetti M	2009	Cell Oncol2009，31，3：	1
	4	Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis显示文摘	Sonveaux P Copetti T De Saedeleer C J	2012	Plos One2012，7，33：	1
	5	Chest sonography:a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome显示文摘	Copetti R Soldati G Copetti P	2008	Cardiovasc Ultrasound2008，6，：	1
	6	Tar-geting the lactate transporter MCT1 in endothelial cells inhibitslactate-induced HIF-1 activation and tumor angiogenesis 显示文摘	SONVEAUX P COPETTI T DE SAEDELEER CJ	2012	PLoS One2012，7，33：	1
	7	Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute re- spiratory distress syndrome 显示文摘	Copetti R Soldati G Copetti P	2008	Cardiovasc Ultrasound2008，6，1：	1
	8	Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratorydistress syndrorne 显示文摘	Copetti R Soldati G Copetti P	2008	Cardiovasc Ultra- sound2008，29，6：	1
	9	Chest sonography : a useful tool to diffe- rentiate acute cardiogenic pulmonary edema from acute respiratory dis- tress syndrome 显示文摘	Copetti R Soldati G Copetti P	2008	Cardiovasc Ultrasound2008，6，：	1
	10	Targe-ting the lactate transporter MCT1 in endothelial cells inhibits lac-tate induced HIF - 1 activation and tumor angiogenesis显示文摘	SONVEAUX P COPETTI T DE SAEDELEER C J	2012	PLoSOne2012，7，33：	1
	11	Targeting the lactate transporter MCTI in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis 显示文摘	Sonveaux P Copetti T De Saedeleer CJ	2012	PLoS One2012，7，33：	1
	12	Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis 显示文摘	Sonveaux P Copetti T De Saedeleer C J	2012	PLoS One2012，7，33：	1
	13	Chest sonography:a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome显示文摘	Copetti R Soldati G Copetti P		0，，：	1
	14	Chest sonography , a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome 显示文摘	Copetti R Soldati G Copetti P	2008	Cardiovascular Ultrasound2008，29，6：	1
	15	Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis显示文摘	Sonveaux P Copetti T De Saedeleer C J	2012	PLoS One2012，7，33：	1
	16	Chest sonography:a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome显示文摘	Copetti R Soldati G Copetti P		0，，：	1
	17	Targeting the lac-tate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis显示文摘	Sonveaux P Copetti T De Saedeleer CJ	2012	PLoS One2012，7，33：	1

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