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| 1 | Prevalence of Helicobacter pylori infection and intestinal metaplasia in subjects who had undergone surgery for gastric adenocarcinoma in Northwest Italy显示文摘AIM: To investigate the seroprevalence of Helicobacter pylori(H pylorri) infection and its more virulent strains as well as the correlation with the histologic features among patients who had undergone surgery for gastric cancer (GC).METHODS: Samples from 317 (184 males, 133females, mean age 69±3.4 years) consecutive patients who had undergone surgery for gastric non-cardia adenocarcinoma were included in the study. Five hundred and fifty-five (294 males, 261 females, mean age 57.3±4.1 years) patients consecutively admitted to the Emergency Care Unit served as control. Histological examination of tumor, lymph nodes and other tissues obtained at the time of surgery represented the diagnostic 'gold standard'. An enzyme immunosorbent assay was used to detect serum anti-H pylori(IgG)antibodies and Western blotting technique was utilized to search for anti-CagA protein (IgG).RESULTS: Two hundred and sixty-one of three hundred and seventeen (82.3%) GC patients and 314/555 (56.5%)controls were seropositive for anti-H pylori (P<0.0001;OR, 3.58; 95%CI, 2.53-5.07). Out of the 317 cases, 267(84.2%) were seropositive for anti-CagA antibody vs 100 out of 555 (18%) controls (P<0.0001; OR, 24.30;95%CI, 16.5-35.9). There was no difference between the frequency of H pyloriin intestinal type carcinoma (76.2%) and diffuse type cancer (78.8%). Intestinal metaplasia (IM) was more frequent but not significant in the intestinal type cancer (83.4% vs 75.2% in diffuse type and 72.5% in mixed type). Among the patients examined for IM, 39.8% had IM type Ⅰ, 8.3% type Ⅱ and 51.9% type Ⅲ (type Ⅲ vs others, P = 0.4).CONCLUSION; This study confirms a high seroprevalence of H pyloriinfection in patients suffering from gastric adenocarcinoma and provides further evidence that searching for CagA status over H pylori infection might confer additional benefit in identifying populations at greater risk for this tumor. | Giorgio Palestro Rinaldo Pellicano Gian Ruggero Fronda Guido Valente Marco De Giuli Tito Soldati Agostino Pugliese Stefano Taraglio Mauro Garino Donata Campra Miguel Angel Cutufia Elena Margaria Giancarlo Spinzi Aldo Ferrara Giorgio Marenco Mario Rizzetto Antonio Ponzetto | 2005 | World Journal of Gastroenterology2005，11，45： | 5 |
| 2 | New obesity classification criteria as a tool for bariatricsurgery indication显示文摘Obesity plays relevant pathophysiological role in the development of health problems, arising as result of complex interaction of genetic, nutritional, and metabolic factors. Due to the role of adipose tissue in lipid and glucose metabolism, and low grade inflammation, it is necessary to classify obesity on the basis of body fat composition and distribution, rather than the simply increase of body weight, and the Body Mass Index. The new term of adiposopathy(‘‘sick fat'') clearly defines the pathogenic role of adipose tissue. Four phenotypes of obese individuals have been described:(1) normal weight obese(NWO);(2) metabolically obese normal weight;(3) metabolically healthy obese; and(4) metabolically unhealthy obese or 'at risk' obese. Moreover, sarcopenic obesity has been related to all the phenotypes. The category of normal weight lean, represented by metabolically healthy normal weight has been classified to distinguish from NWO. It is crucial to recommend a bariatric surgery taking into account adiposopathy and sick fat that occurs with the expansion of fat mass, changing the inflammatory and metabolic profile of the patient. Body fat percentage and genetic polymorphism have to be evaluated to personalize the best bariatric surgery intervention. | Antonino De Lorenzo Laura Soldati Francesca Sarlo Menotti Calvani Nicola Di Lorenzo Laura Di Renzo | 2016 | World Journal of Gastroenterology2016，22，2： | 3 |
| 3 | International evidence-based recommendations for point-of-care lung ultrasound显示文摘 | Giovanni Volpicelli Mahmoud Elbarbary Michael Blaivas Daniel A. Lichtenstein Gebhard Mathis Andrew W. Kirkpatrick Lawrence Melniker Luna Gargani Vicki E. Noble Gabriele Via Anthony Dean James W. Tsung Gino Soldati Roberto Copetti Belaid Bouhemad Angelika | 2012 | Intensive Care Medicine2012，，4： | 2 |
| 4 | Ultrasound lung comets for the differential diagnosis of acute cardiogenic dyspnoea : a comparison with natriuretic peptides 显示文摘 | Gargani L Frassi F Soldati G | 2008 | Eur J Heart Fail2008，10，1： | 1 |
| 5 | The ultrasonographic deep sul-cus sign in traumatic pneumothorax显示文摘 | Soldati G Testa A Pignataro G | 2006 | Ultrasound Med Biol2006，32，8： | 1 |
| 6 | Role of Toxoplasma gondii myosin A in powering parasite gliding and host cell invasion 显示文摘 | Meissner M Schluter D Soldati D | 2002 | Science2002，29，8： | 1 |
| 7 | Cold tolerance ofmaize seedlings as determined by root morphology and photosyn-thetic traits显示文摘 | Hund A Fracheboud Y Soldati A | 2008 | European Journal of Agronomy2008，28，： | 1 |
| 8 | Growth of human melanoma xenografts is suppressed by systemic angiostatin gene therapy显示文摘 | Monica R Enrica M Soldati S | 2001 | Cancer Gene Therapy2001，，8： | 1 |
| 9 | River flood forecasting with neural network model显示文摘 | CAMPOLO M ANDREUSSI P SOLDATI A | 1999 | Water Resour Res1999，35，4： | 1 |
| 10 | 'Synthetic' comets : a new look at lung sonography 显示文摘 | Soldati G Giunta V Sher S | 2011 | Ultrasound Med Biol2011，37，11： | 1 |
| 11 | Relevance of Mediterra- nean diet and glucose metabolism for nephrolithiasis in obese sub- jects显示文摘 | Soldati L Bertoli S Terranegra A | 2014 | J Transl Med2014，12，： | 1 |
| 12 | The microneme protein MIC4, or an MIC4-1ike protein, is expressed within the macrogamete and associated with oocyst wall formation in Toxoplasma gondii显示文摘 | Ferguson D J Brecht S Soldati D | 2000 | Int J Parasitol2000，30，11： | 1 |
| 13 | Cross-Layer Resource Allocation Model for Cellular-Relaying Network Performance Ev- aluation显示文摘 | TIMUS B SOLDATI P DONGWOO K | 2011 | IEEE Transactions on Vehicular Technology2011，60，6： | 1 |
| 14 | New insights in- to myosin evolution and elassification显示文摘 | FOTH B J GOEDECKE M C SOLDATI D | 2006 | Proc Natl Acad Sci USA2006，103，10： | 1 |
| 15 | Iatrogenic risk of permanent pacemaker and defibrillator implantation显示文摘 | Bongiomi MQ Di Cori A Soldati E | | 0，，： | 1 |
| 16 | End-to-end op- erative repair of Achilles tendon rupture 显示文摘 | Soldatis JJ Goodfellow DB Wilber JH | 1997 | Am J Sports Med1997，25，1： | 1 |
| 17 | Sau-PCR,a novel ampli- fication technique for genetic fingerprinting of microorganisms 显示文摘 | Corieh V Mattiazzi A Soldati E | 2005 | Appl Environ Microbiol2005，71，10： | 1 |
| 18 | Occult traumatic pneumothorax:diagnosticaccuracy of lung ultrasonography in the emergency department显示文摘 | Soldati G Testa A Sher S | 2008 | Chest2008，133，1： | 1 |
| 19 | Horizontal partial laryngectomy for supraglottic squamous cell carcinoma显示文摘 | BRON L P SOLDATI D MONOD M L | 2005 | Eur Arch Otorhinolaryngol2005，262，： | 1 |
| 20 | High resolutionFIB-TEM and FIB-SEM characterization of electrode/elec-trolyte interfaces in solid oxide fuel cells materials显示文摘 | Analia L Soldati Laura B Horacio T | 2011 | Inter-national Journal of Hydrogen Energy2011，，36： | 1 |
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