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| 1 | FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus显示文摘AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. | Keyur Patel Mireen Friedrich-Rust Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem | 2011 | World Journal of Gastroenterology2011，17，41： | 4 |
| 2 | Context Effects in Subjective Mental Workload Ratings 显示文摘 | Colle H A Reid G B | 1998 | Human Factors1998，40，4： | 1 |
| 3 | Electrochemical and spectroscopic studies of ethanol oxidation on Pt stepped surfaces modified by tin adatoms 显示文摘 | Del Colle V Souza-Garcia J Tremiliosi G | 2011 | Physical Chemistry Chemical Physics2011，13，12： | 1 |
| 4 | International HRM inthe 21st century: Emerging themes and contemporary debates 显示文摘 | SCUllION H COllINGS D G GUNNGlE P | 2007 | Human Resource Management Journal2007，17，4： | 1 |
| 5 | Preimplantation genetic diag- nosis for gender selection in the USA显示文摘 | Colls P Silver L Olivera G | 2009 | Reprod Biomed On- line2009，19，2： | 1 |
| 6 | Guidelines on CMVcongenital infection显示文摘 | Coll O Benoist G Ville Y | 2009 | J Perinat Med2009，37，5： | 1 |
| 7 | Uptake and resource allocation of ammonium and nitrate in temperate seagrasses Posidonia and Amphibolis 显示文摘 | Nayar S Collings G J Miller D J Bryars S Cheshire A C | 2010 | Marine Pollution Bulletin2010，60，9： | 1 |
| 8 | Supportive Periodontal therapy using mechanical instrumentation or 2%minocyeline gel:a 12month randomized,controlled,single masked pilot study显示文摘 | Me Coll E Patel K Dahlen G | 2006 | J Clin Periodontol2006，33，2： | 1 |
| 9 | Synthesis of dienic fluorinated analogs of insect sex pheromone显示文摘 | CAMPS F COLL J FABRIAS G | 1984 | Tetrahedron1984，40，： | 1 |
| 10 | All chemical YBa2Cu3O7 superconducting multilayers: Critical role of CeO2 cap layer flatness显示文摘 | M. Coll J. Gàzquez R. Huhne B. Holzapfel Y. Morilla J. García-López A. Pomar F. Sandiumenge T. Puig X. Obradors | 2009 | Journal of Materials Research2009，，4： | 1 |
| 11 | Modelling and hourly simulation of a solar ejector cooling system显示文摘 | VIDAL H COLLE S PEREIRAL G | 2006 | Applied Thermal Engineering2006，26，7： | 1 |
| 12 | The impact of peripheral arterial disease on health-related quality of life in the peripheral arterial disease awareness,risk,and treatment:New resources for survival(PARTNERS)program显示文摘 | Regensteiner J G Hiatt W R coll J R | 2008 | Vasc Med2008，13，1： | 1 |
| 13 | Nanoparticles in rectal can- cer imaging显示文摘 | Koh DM Brown G Collings DJ | 2009 | Cancer Biomark2009，5，2： | 1 |
| 14 | Global Talent Management显示文摘 | SCULLION H COLLINGS D G CALIGIURI P | 2010 | Journal of World Busi- ness2010，45，2： | 1 |
| 15 | On the influence of meteorological input on photochemical modelling of a severe episode over a coastal area显示文摘 | Pirovano G Coll L Bedogni M | 2007 | Atmospheric Environment2007，41，： | 1 |
| 16 | Communicative abillties in autism:Evidence for attentional deficits显示文摘 | BARA B G BUCCIARELLI M COLLE L | 2001 | Brain and Lenguage2001，77，2： | 1 |
| 17 | MaxiUary distrac- tion in cleft lip palate patients: A review of six cases显示文摘 | Swennen G Colle F De May A | 1999 | J Craniofac Surg1999，10，2： | 1 |
| 18 | 显示文摘 | NEWSOME W H YEUNG J M COLLING P G | 1993 | J AOAC Int1993，76，： | 1 |
| 19 | Ezetimibe effectively decreases LDL-cholesterol in HIV-infected patients 显示文摘 | Coll B Aragones G Parra S | 2006 | AIDS2006，20，12： | 1 |
| 20 | Accelerated atherosclemsis,an extra articular feature of rheumatoid arthritis?显示文摘 | Van Doornum S Mc Coll G Wicks ZP | 2002 | Arthdtis Rheum2002，46，4： | 1 |
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