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| 1 | 猪舍环境温湿度对育成猪的生理及生产指标的影响显示文摘试验采用美国 DSI公司生产的动物生理参数无线遥测系统与猪舍环境参数及动物行为自动检测系统研究了长白猪在夏季湿热环境下的行为生理反应。结果表明猪舍高温将导致猪的体温升高、心率加快 ,猪的生产性能降低等热应激反应 ,高温高湿环境下猪的热应激反应更为严重 ,高温时环境湿度增大 10 % ,相当于环境温度升高1℃对猪的影响。环境温度对猪的体温和心率影响极显著 ;环境湿度对猪的体温影响显著 。 | 汪开英 苗香雯 崔绍荣 Coen M Hogenboom R.Geers | 2002 | 农业工程学报2002,18,1: | 55 |
| 2 | 四川紫色土区土壤养分径流和泥沙流失特征研究显示文摘对四川紫色土区土壤养分径流和泥沙流失特征进行了研究 ,结果表明 :土壤氮素主要随径流流失 ,主要土内径流和地下径流携带NO3 N所造成 ;土壤磷主要随泥沙流失 ,泥沙中的养分有明显的富集现象 ,但不同流域以及不同雨次的富集系数明显不同 ;同时泥沙N、P的富集系数与泥沙浓度有一定的关联 ,一般是泥沙浓度高 ,N富集系数低 。 | 李宪文 史学正 Coen Ritsema | 2002 | 资源科学2002,24,6: | 24 |
| 3 | Functional brain imaging of gastrointestinal sensation in health and disease显示文摘It has since long been known, from everyday experience as well as from animal and human studies, that psychological processes-both affective and cognitive- exert an influence on gastrointestinal sensorimotor function. More specifi cally, a link between psychological factors and visceral hypersensitivity has been suggested, mainly based on research in functional gastrointestinal disorder patients. However, until recently, the exact nature of this putative relationship remained unclear, mainly due to a lack of non-invasive methods to study the (neurobiological) mechanisms underlying this relationship in non-sleeping humans. As functional brain imaging, introduced in visceral sensory neuroscience some 10 years ago, does provide a method for in vivo study of brain-gut interactions, insight into the neurobiological mechanisms underlying visceral sensation in general and the influence of psychological factors more particularly, has rapidly grown. In this article, an overview of brain imaging evidence on gastrointestinal sensation will be given, with special emphasis on the brain mechanisms underlying the interaction between affective & cognitive processes and visceral sensation. First, the reciprocal neural pathways between the brain and the gut (brain- gut axis) will be briefky outlined, including brain imaging evidence in healthy volunteers. Second, functional brain imaging studies assessing the influence of psychological factors on brain processing of visceral sensation in healthy humans will be discussed in more detail. Finally, brain imaging work investigating differences in brain responses to visceral distension between healthy volunteers and functional gastrointestinal disorderpatients will be highlighted. | Lukas Van Oudenhove Steven J Coen Qasim Aziz | 2007 | World Journal of Gastroenterology2007,13,25: | 9 |
| 4 | 应用红外传感器进行母猪的发情及最佳配种时间鉴定显示文摘应用红外行为传感器监测系统对 38头母猪的发情行为及最佳配种时间进行鉴定 .结果表明 ,该系统鉴定的准确率 (84 .2 %)较人工观察法鉴定有明显提高 ,同时可大大降低生产成本 ,具有较大的推广应用价值 . | 汪开英 苗香雯 谢江明 Coen M Hogenboom 邵胜育 | 2001 | 浙江大学学报(农业与生命科学版)2001,27,6: | 8 |
| 5 | 骨科教程 膝关节内侧副韧带及内侧结构的损伤显示文摘内侧副韧带浅层及其他内侧的膝关节稳定结构——如,内侧副韧带深层和后斜韧带——是损伤最为多见的膝关节韧带性结构。 | Coen A. Wijdicks, PhD Chad J. Griffith, MD Steinar Johansen, MD Lars Engebretsen, MD, PhD Robert F. LaPrade, MD, PhD 夏志敏(译) | 2010 | 中华骨科杂志2010,30,9: | 8 |
| 6 | Quality of terrestrial data derived from UAV photogrammetry:A case study of Hetao irrigation district in northern China显示文摘Most crops in northern China are irrigated,but the topography affects the water use,soil erosion,runoff and yields.Technologies for collecting high-resolution topographic data are essential for adequately assessing these effects.Ground surveys and techniques of light detection and ranging have good accuracy,but data acquisition can be time-consuming and expensive for large catchments.Recent rapid technological development has provided new,flexible,high-resolution methods for collecting topographic data,such as photogrammetry using unmanned aerial vehicles(UAVs).The accuracy of UAV photogrammetry for generating high-resolution Digital Elevation Model(DEM)and for determining the width of irrigation channels,however,has not been assessed.A fixed-wing UAV was used for collecting high-resolution(0.15 m)topographic data for the Hetao irrigation district,the third largest irrigation district in China.112 ground checkpoints(GCPs)were surveyed by using a real-time kinematic global positioning system to evaluate the accuracy of the DEMs and channel widths.A comparison of manually measured channel widths with the widths derived from the DEMs indicated that the DEM-derived widths had vertical and horizontal root mean square errors of 13.0 and 7.9 cm,respectively.UAV photogrammetric data can thus be used for land surveying,digital mapping,calculating channel capacity,monitoring crops,and predicting yields,with the advantages of economy,speed and ease. | Hongming Zhang Jiangtao Yang Jantiene E.M.Baartman Shuqin Li Bei Jin Wenting Han Xiaomei Yang Lingtong Gai Coen J.Ritsema Violette Geissen | 2018 | International Journal of Agricultural and Biological Engineering2018,11,3: | 4 |
| 7 | Coeliac disease in Dutch patients with Hashimoto’s thyroiditis and vice versa显示文摘AIM: To define the association between Hashimoto’s thyroiditis and coeliac disease in Dutch patients. METHODS: A total of 104 consecutive patients with Hashimoto’s thyroiditis underwent coeliac serological tests (antigliadins, transglutaminase and endomysium antibodies) and HLA-DQ typing. Small intestinal biopsy was performed when any of coeliac serological tests was positive. On the other hand, 184 patients with coeliac disease were subjected to thyroid biochemical (thyroid stimulating hormone and free thyroxine) and thyroid serological tests (thyroglobulin and thyroid peroxidase antibodies). RESULTS: Of 104 patients with Hashimoto’s thyroiditis, sixteen (15%) were positive for coeliac serology and five patients with documented villous atrophy were diagnosed with coeliac disease (4.8%; 95% CI 0.7-8.9). HLA-DQ2 (and/or -DQ8) was present in all the five and 53 patients with Hashimoto’s thyroiditis (50%; 95% CI 43-62). Of 184 patients with coeliac disease, 39 (21%) were positive for thyroid serology. Based on thyroid biochemistry, the 39 patients were subclassified into euthyroidism in ten (5%; 95% CI 2-9), subclinicalhypothyroidism in seven (3.8%; 95% CI 1.8-7.6), and overt hypothyroidism (Hashimoto’s thyroiditis) in 22 (12%; 95% CI 8-16). Moreover, four patients with coeliac disease had Graves’ disease (2%; 95% CI 0.8-5) and one patient had post-partum thyroiditis. CONCLUSION: The data from a Dutch population confirm the association between Hashimoto’s thyroiditis and coeliac disease. Screening patients with Hashimoto’s thyroiditis for coeliac disease and vice versa is recom- mended. | Muhammed Hadithi Hans de Boer Jos WR Meijer Frans Willekens Jo A Kerckhaert Roel Heijmans Amado Salvador Pea Coen DA Stehouwer Chris JJ Mulder | 2007 | World Journal of Gastroenterology2007,13,11: | 4 |
| 8 | Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study显示文摘 | Roger K. Schindhelm Jacqueline M. Dekker Giel Nijpels Lex M. Bouter Coen D.A. Stehouwer Robert J. Heine Michaela Diamant | 2006 | Atherosclerosis2006,,2: | 3 |
| 9 | 华南石炭纪杜内-维宪界线期牙形石演化和层型标志显示文摘据华南牙形石系统研究成果,提出石炭纪杜内阶-维宪阶候选全球界线层型剖面、剖面点和化石标志.选择代表扬子板块边缘和内部,及不同沉积相型的剖面,分析各剖面的沉积微相和旋回(层序)构成,统计牙形石在剖面上的分异度和丰度,研究各类(属)牙形石相分布和生态环境.从而确定在分布广泛、浮游生存的gnathodids类中选择化石标志.完善和建立杜内-维宪过渡期各类(属)牙形石演化谱系,划分早石炭世牙形石发展阶段,即Siphonodella阶段,Gnathodustypicus阶段和Gnathodusbilineatus阶段,进一步选定praebilineatus带的底界是两个发展阶段的转换面.最后提出了石炭系杜内阶-维宪阶全球界线候选层型为台盆相广西柳州碰冲剖面,界线点为层58的底,界线层型的牙形石标志定在Gnathodussemiglaber支系中Gnathoduspraebilineatus的首现. | 田树刚 M. Coen | 2005 | 中国科学(D辑)2005,35,11: | 3 |
| 10 | Emerging pollutants in the environment:A challenge for water resource management显示文摘A significant number of emerging pollutants(EPs)resulting from point and diffuse pollution is present in the aquatic environment.These are chemicals that are not commonly monitored but have the potential to enter the environment and cause adverse ecological and human health effects.According to the NORMAN network,at least 700 substances categorized into 20 classes,have been identified in the European aquatic environment.In light of their potential impact action is urgently required.In this study,we present a concept that shows the current state of art and challenges for monitoring programs,fate and risk assessment tools and requirements for policies with respect to emerging pollutants as a base for sustainable water resource management.Currently,methods for sampling and analysis are not harmonized,being typically focused on certain EP classes.For a number of known highly hazardous EPs detection limits are too high to allow proper risk assessment.For other EPs such as microplastics method development is in its infancy.Advanced ultra-sensitive instrumental techniques should be used for quantitative determination of prioritized EPs in water,suspended matter,soil and biota.Data on EPs'and their metabolites'properties that determine their fate in the environment are often not available.National surveys on water quality often use different parameters for water quality assessment and often do not include EPs.A harmonized monitoring of surface and groundwater is not yet achieved and urgently required.Specific component integrated into models assessing the fate of EPs in a multi compartment environmental approach are missing and must be developed.The main goal of risk assessment is the overall protection of ecological communities in the aquatic environment and human health.New methods for assessing the cumulative risks from combined exposures to several stressors,including mixtures of EPs in a multi-scale approach are required.A combination of regulations and management measures with respect to use/emissions of EPs into the environment,as well as to their occurrence in the environment are fundamental to reach an efficient water resource management. | Violette Geissen Hans Mol Erwin Klumpp Günter Umlauf Marti Nadal Martine van der Ploeg Sjoerd E.A.T.M.van de Zee Coen J.Ritsema | 2015 | International Soil and Water Conservation Research2015,3,1: | 3 |
| 11 | Effect of B vitamin supplementation on plasma homocysteine levels in celiac disease显示文摘AIM: To investigate the effect of vitamin supplements on homocysteine levels in patients with celiac disease. METHODS: Vitamin B6, folate, vitamin B12, and fasting plasma homocysteine levels were measured in 51 consecutive adults with celiac disease [median (range) age 56 (18-63) years; 40% men, 26 (51%) had villous atrophy, and 25 (49%) used B-vitamin supplements] and 50 healthy control individuals matched for age and sex. Finally, the C677T polymorphism of 5,10-methylene tetrahydrofolate reductase (MTHFR) was evaluated in 46 patients with celiac disease and all control individuals. RESULTS: Patients with celiac disease and using vitamin supplements had higher serum vitamin B6 (P = 0.003),folate (P < 0.001), and vitamin B12 (P = 0.012) levels than patients who did not or healthy controls (P = 0.035, P < 0.001, P = 0.007, for vitamin B6, folate, and vitamin B12, respectively). Lower plasma homocysteine levels were found in patients using vitamin supplements than in patients who did not (P = 0.001) or healthy controls (P = 0.003). However, vitamin B6 and folate, not vitamin B12, were significantly and independently associated with homocysteine levels. Twenty-four (48%) of 50 controls and 23 (50%) of 46 patients with celiac disease carried the MTHFR thermolabile variant T-allele (P = 0.89). CONCLUSION: Homocysteine levels are dependent on Marsh classification and the regular use of B-vitamin supplements is effective in reduction of homocysteine levels in patients with celiac disease and should be considered in disease management. | Muhammed Hadithi Chris JJ Mulder Frank Stam Joshan Azizi J Bart A Crusius Amado Salvador Pea Coen DA Stehouwer Yvo M Smulders | 2009 | World Journal of Gastroenterology2009,15,8: | 3 |
| 12 | Conodont evolution and stratotype sign of carboniferous Tournaisian-Visean boundary in South China显示文摘A stratotype section, boundary point and conodont sign have been recommended for GSSP of the Tournaisian-Visean boundary, based on studies of sectional sedimentology, conodont facies and phylogeneses in South China. Two areas representing margin and inner of the Yangtzi Plate and three sections of different facies were chosen, i.e. the Longdianshan sec-tion of the platform facies in Liuzhou of Guangxi, the Yudong section of the ramp facies in Shidian of Yunnan and the Pengchong section of the basin facies in Liuzhou of Guangxi. Stratigraphic frameworks of two areas were set up by systematical studies of carbonate facies and cycles. Conodont facies-distribution and paleoecologic conditions were researched on statistics of fossil variation and richness, and a kind of planktonic conodont, gnathodids that were widespread, is chosen to select the sign-fossil from it. Seven conodont pedigrees were supplemented or erected by studies of statistics and transitional forms. Conodont evolution in the Early Carboniferous could be divided into three stages, i.e. the Siphonodella stage, the Gnathodus typicus stage and the Gnathodus bilineatus stage. The transform-surface between the later two stages could be put as the Tournaisian-Visean boundary. Finally, this paper proposes that the Pengchong section can be the stratotype candidate of the Tournaisian-Visean boundary, the boundary point be put at the bottom of bed 58 and the stratotype sign of conodont be the first occurrence of Gnathodus praebilineatus of the Gnathodus semiglaber branch. | Michel Coen | 2005 | Science China Earth Sciences2005,48,12: | 3 |
| 13 | 二甲双胍长期治疗2型糖尿病患者以及维生素B12缺乏的危险性:随机安慰剂对照研究(摘要)显示文摘目的 研究接受胰岛素治疗的2型糖尿病患者中,二甲双胍所致维生素B12缺乏(〈150pmol/L)、低浓度维生素B12(150—220pmol/L)的发生率,以及叶酸和同型半胱氨酸的浓度。 | Jolien de Jager Adriaan Kooy Philippe Lehert Michiel G Wulffele Jan van der Kolk Daniel Bets Joop Verburg Ab J M Donker Coen D A Stehouwer 许翎岭(译) | 2010 | 英国医学杂志中文版2010,13,5: | 2 |
| 14 | White-light supercontinuum generation with 60- ps pump pulses in a photonic crystal fiber显示文摘 | Stophane Coen | 2001 | Optics Letters2001,26,17: | 2 |
| 15 | The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase 显示文摘 | ZUCCOLA H J FILMAN D J COEN D M | 2000 | Mol Cell2000,5,2: | 1 |
| 16 | Clogging of biliary endoprosthesis: a new perspective显示文摘 | Coene P Groen A Cheng J | 1990 | Gut1990,31,: | 1 |
| 17 | Morphologic changes of extrahepatic bile ducts during obstruction and subsequent decompression by endoprosthesis显示文摘 | Karsten TM Coene PP Van Gulik TM | 1992 | Surgery1992,111,5: | 1 |
| 18 | Molecular mechanisms of antiviral resistance 显示文摘 | Kimberlin D W Coen D M Biron K K | 1995 | Antiviral Res1995,26,4: | 1 |
| 19 | Floricaula:a homeotic gene required for flower development in Antirrhinum majus显示文摘 | Coen E S Romero J M Doyle S | 1990 | Cell1990,63,: | 1 |
| 20 | The war of the whorls : genetic interactions controlling flower development显示文摘 | Coen E S Meyerowitz E M | 1991 | Nature1991,353,: | 1 |