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| 1 | WONCA研究论文摘要汇编——初级医疗中普里西特治疗模式对2型糖尿病患者的干预效果:整群随机对照试验显示文摘背景性功能障碍在2型糖尿病患者中较为普遍,也是糖尿病护理中最易被忽视的并发症之一。患者和医务工作者在糖尿病护理中对讨论性问题感到困难。普里西特治疗(PLISSIT)模式中的性咨询模型可能是有效工具,可以帮助医务工作者与2型糖尿病患者对性问题进行探讨。PLISSIT的含义是许可(Permission)、有限信息(Limited Information)、特别建议(Specific Suggestions)和强化治疗(Intensive Therapy)。尽管在糖尿病护理中经常建议使用PLISSIT模式,但是并没有证据证明其对2型糖尿病患者的有效性。本研究采用整群随机对照试验,评估PLISSIT模式在初级医疗中对2型糖尿病患者的干预效果。方法 /设计招募年龄40~75岁、表示对性功能不满意且愿意与全科医生讨论性问题的2型糖尿病患者。护士向所有参与者发放相关知识传单。干预组中,每例患者依据PLISSIT模式对全科医生进行性问题咨询;认为知识传单信息不足的患者可以预约全科医生进行常规护理。主要结局指标包括性功能、性功能满意度和生活质量;次要结局指标包括抑郁症状、性痛苦、情绪安康、治疗满意度。在研究开始前及研究3、12个月后,通过自我报告问卷对结局指标进行评估。通过电话采访对治疗满意度进行评估。讨论本研究介绍了整群随机对照试验的设计,对初级护理中使用PLISSIT模式对2型糖尿病患者干预的有效性进行研究。针对男性和女性2型糖尿病患者重要指标结果,提出了关于PLISSIT模式有效性的重要和缺失观点。 | Rutte A van Oppen P Nijpels G | 2015 | 中国全科医学2015，18，20： | 5 |
| 2 | Alanine aminotransferase predicts coronary heart disease events: A 10-year follow-up of the Hoorn Study显示文摘 | Roger K. Schindhelm Jacqueline M. Dekker Giel Nijpels Lex M. Bouter Coen D.A. Stehouwer Robert J. Heine Michaela Diamant | 2006 | Atherosclerosis2006，，2： | 3 |
| 3 | Alanine aminotrans- ferase predicts coronary heart disease events: A 10-year follow--up of the Hoorn Study 显示文摘 | Sch/ndhelm RK Dekker JM Nijpels G | 2007 | Arteriosclerosis2007，191，： | 1 |
| 4 | Serum homocysteinelevels are associated with the development d(micro) album-inuria:The Hoorn Study显示文摘 | Jager A Koetense PJ Nijpels G | 2007 | Arterioscler Thmmb Vasc Bio12007，21，： | 1 |
| 5 | Associations between Depressive Symptoms and Insulin Re- sistance:The Hoorn Study显示文摘 | Adriaanse MC Dekker JM Nijpels G | 2006 | Diabetologia(S0012-186X)2006，49，12： | 1 |
| 6 | Are retinal mierovascular abnormalities associated with large artery endothelial dysfunction and intimamedia thickness? The Hoorn Study显示文摘 | van Hecke MV Dekker JM Nijpels G | 2006 | Clin Sci (Land)2006，110，： | 1 |
| 7 | Anine amino trans- ferase predicts coronary heart disease events:A 10-year follow- up of the Hoorn Study 显示文摘 | Schindhelm EK Dekker JM Nijpels G | 2007 | Atherosclerosis2007，191，2： | 1 |
| 8 | Rates and risks for co-morbid depression in patients with type 2diabetes mellitus:results from a communitybased study显示文摘 | Pouwer F Beekman AT Nijpels G Dekker JM Snoek FJ Kostense PJ | 2003 | Diabetologia2003，46，7： | 1 |
| 9 | Com- bined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First-Phase Glucose-Stimulated Insulin Secretion During Hyperglycemic Clamps 显示文摘 | SIMONIS-BIK A M NIJPELS G VAN HAEFTEN T W | 2010 | Diabetes2010，59，1： | 1 |
| 10 | Alanine aminotransferase predicts coronary heart disease events:a 10-year follow-up of the Hoorn Study显示文摘 | Schindhelm RK Dekker JM Nijpels G | 2007 | Atherosclerosis2007，191，2： | 1 |
| 11 | Coffee consumption and incidence of impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes: the Hoorn Study显示文摘 | Van Dam RM Dekker JM Nijpels G | 2004 | Diabetologia2004，47，： | 1 |
| 12 | Prognostic value of adiponectin for cardiovascular disease and mortality 显示文摘 | Dekker J Funahashi T Nijpels G | 2008 | J Clin Endocrin Metab2008，93，4： | 1 |
| 13 | Homocysteins, Sadenosyl methionine and S-adenosyl homocysteine are associated with retinal microvascular abnormalities: the Hoorn Study 显示文摘 | VAN HECKE M V DEKKER J M NIJPELS G | 2008 | Clin Sci(Lond)2008，114，7： | 1 |
| 14 | Are retinal microvascular abnormalities associated with large artery endothelial dysfunction and intima-media thickness? The Hoorn Study显示文摘 | van Hecke MV Dekker JM Nijpels G | 2006 | Clin Sci(Lond)2006，110，5： | 1 |
| 15 | Prevention of deterioration of ventricular fibrillation by basic life support during out - of - hospital cardiac arrest 显示文摘 | Waalewijn RA Nijpels MA Tijssen JG | 2002 | Resuscitation2002，54，1： | 1 |
| 16 | Cognitive functioning in elderly persons with type 2 diabetes and metabolic syndrome: the Hoorn study显示文摘 | van den Berg E Dekker JM Nijpels G | 2008 | Dement Geriatr Cogn Disord2008，26，26： | 1 |
| 17 | Serum homocysteine levels are associated with the development of(micro) albuminuria:The hoorn study显示文摘 | Jager A Kostense P J Nijpels G | 2007 | Arterioscler Thromb Vasc Biol2007，21，1： | 1 |
| 18 | Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoom Study显示文摘 | Schindhelm RK Dekker JM Nijpels G | 2007 | Atheroslerosis2007，191，2： | 1 |
| 19 | Inflammation and endothelial dysfunction are associated with retinopathy: the Hoorn Study显示文摘 | M. V. Hecke J. M. Dekker G. Nijpels A. C. Moll R. J. Heine L. M. Bouter B. C. P. Polak C. D. A. Stehouwer | 2005 | Diabetologia2005，，7： | 1 |
| 20 | Alanine aminotransferase predicts coronary heart disease events:a 10-year follow-up of the Hoorn Study显示文摘 | Schindhelm RK Dekker JM Nijpels G | 2007 | Atherosclerosis2007，191，2： | 1 |
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