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84篇 您的检索式:作者名="Coco S"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Treatment of acute respiratory failure secondaryto pulmonary edema with bilevel positive airway pressure by nasal mask 显示文摘Lo Coco A Vitale G Marchese S 2001Monaldi Arch Chest Dia2001,63,:1
3Efficacy of caspofungin alone and in combination with voriconazole in guinea pig model of invasive aspergillosis显示文摘Kirkpatrick W R Perea S Coco B J 2002Antimicrob Agents Chemother2002,46,:1
4COCA: A Novel 3-D FE Simulator for the Design of TWTs Multistage Collectors显示文摘Coco S Emma F Laudani A 2001IEEE Trans Electron Devices2001,48,1:1
5A multilayer perceptron neural model for the differentiation of laplacian 3-D finite-element solutions 显示文摘Capizzi G Coco S Laudani A 2003IEEE Transactions on Magnetics2003,39,3:1
6A neural network approach for the differentiation of numerical solutions of 3-D electromagnetic problems 显示文摘Capizzi G Coco S Giuffrida C 2004IEEE Transactions on Magnetics2004,40,2:1
7ATRA and arsenic trioxide (ATO) versus ATRA and idarubicin (AI- DA) for newly diagnosed, non high-risk acute promyelo- cytie leukemia (APL) : results of the phase III, prospec- tive, randomized, intergroup APL0406 study by the Ital- ian-German cooperative groups GIMEMA-SAL-AMLSG 显示文摘Lo Coco F Avvisati G Orlando S M 2012Blood2012,120,1:1
8Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosis显示文摘KirkpatrickWR Perea S Coco BJ 2002Antimicrob Agents Chemother2002,46,8:1
9Variability of GPS satellite differential group delay biases显示文摘Coco David S 1991IEEE Trans on AES1991,27,6:1
10Histone deacetylases:a common molecular target for differentiation treatment of acute myeloid leukemias?显示文摘Minucci S Nervi C Lo Coco F 2001Oncogene2001,20,24:1
11Treatment of acute respiratory failure secondary to pulmonary edema with bilevel positive airway pressure by nasal mask显示文摘L O COCO A VITALE G MARCHESE S 1997Monaldi Arch Chest Dis1997,52,5:1
12Variability of GPS satellite differential group delay biases显示文摘Coco D S 1991IEEE transaction on aerospace and electrical systems1991,27,6:1
13Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias? 显示文摘Minucci S Nervi C Lo Coco F 2001Oncogene2001,20,24:1
14Volatile composition of Baga red wine: assessment of the identification of the would-be impact odoumnts显示文摘ROCHA S M RODRIGUES F COCO P 2004Analytica Chimica Acta2004,513,1:1
15Reducing the incidence of denture stomatitis:are denture cleansers sufficient?显示文摘Jose A Coco BJ Milligan S 2010J Prosthodont2010,19,4:1
16Noninvasive positive-pressure ventilation in ALS:predictors of tolerance and survival显示文摘Lo Coco D Marchese S Peseo MC Neurology0,,:1
17Storage and release of ATP from astrocytes in culture显示文摘Coco S Calegari F Pravettoni E 2003J Biol Chem2003,278,2:1
18Transcribed-Ultra conserver region expression is associated with outcome in high-risk neuroblastoma显示文摘Scaruffi P Stigliani S Coco S 2009BMC Cancer2009,9,:1
19Are attachment dimensions associated with infertility-related stress in couples undergoing their first IVF treatment?A study on the individual and cross-partner effect显示文摘Donarelli Z Lo Coco G Gullo S 2012Hum Reprod2012,27,11:1
20Treatment of acute respiratory failure secondary to pulmonary oedema with bi-level positive airway pressure by nasal mask 显示文摘Lo Coco A Vitale G Marchese S 1997Monaldi Arch Chest Dis1997,52,5:1
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