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	题名	作者	年代	出处	被引量
1	胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。	Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉叶鹏	2017	中华高血压杂志2017，25，9：	2
2	Functional mutation in the promoter region of thrombomodulin gene in relation to carotid atherosclerosis 显示文摘	Li YH Chen CH Yeh PS	2001	Atherosclerosis2001，154，1：	1
3	Co-stimulation of T cells for tumor unmunity显示文摘	Chen LP Linsley PS Hellstxom KE	1993	Immunology Today1993，14，10：	1
4	New observations on atrial fibrillation in patients with the Wollf-Parkinson-White syndrome显示文摘	Chen PS Pressley JC Tang AS	1992	J Am Coll Cardiol1992，19，5：	1
5	The role of the VEGF-C/VEGFR3 axis in cancer progression显示文摘	Su JL Yen CJ Chen PS		0，，4：	1
6	Quantitative analysis of the effect of the mutation frequency on the affinity maturation of single chain Fv antibodles显示文摘	Daugherty PS Chen G Iverson BL	2000	Proc Natl Acad Sci U S A2000，97，5：	1
7	Costimulatiou of T cells for tumor immunity显示文摘	Chen L Linstey PS Hellstrom KE	1993	Immunol Today1993，14，：	1
8	The deter- minants and longitudinal course of post - stroke mild cognitive impairment 显示文摘	Sachdev PS Chen X Brodaty H	2009	J lnt Neuropsychol Soc2009，15，：	1
9	Photodynamic therapy for endodontic disinfection显示文摘	Soukos NS Chen PS Morris JT	2006	J Endod2006，32，10：	1
10	Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells显示文摘	Su JL Chen PS Chien MH	2008	Cancer Cell2008，13，6：	1
11	Expressed Cp G island sequence tag microarray for dual screening of DNA hypermethylation and gene silencing in cancer cells显示文摘	Shi H Yan PS Chen CM	2002	Cancer Res2002，62，11：	1
12	In vivo near-infrared fluorescence imaging of integrin ανβ3 in brain tumor xenografts显示文摘	Chen X Conti PS Moats RA	2004	Cancer Res2004，64，：	1
13	The role of the VEGF-C/ VEGFR-3 axis in cancer progression 显示文摘	Su JL Yen C J Chen PS	2007	Br J Cancer2007，96，：	1
14	Role of electrostatic interactions in cohesion of bacterial biofilms显示文摘	Chen X Stewart PS	2002	Appl Microbiol Biotechnol2002，59，：	1
15	Dependence of cardiac ^11C- meta-hydroxyephedrine retention on norepinephrine transporter density显示文摘	Raffel DM Chen W Sherman PS	2006	J Nucl Med2006，47，9：	1
16	Beta 1--Integrin-mediated glioma cell adhesion and free radical--induced apoptosis are regulated by binding to a C-terminal domain of PG--M/versican显示文摘	WuY Chen L Zheng PS	2002	J Biol Chem2002，277，12：	1
17	Dysregulation of microRNAs in cancer显示文摘	Chen PS Su JL Hung MC	2012	J Biomed Sci2012，19，：	1
18	FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low g-glutamyltranspeptidase levels显示文摘	Chen HL Chang PS Hsu HC	2002	J Pediatr2002，140，1：	1
19	Palmitoylation of the HIV-1 envelope glycoprotein is critical for viral infectivity显示文摘	Rousso I Mixon MB Chen BK Kim PS	2000	Proc Natl Acad Sci USA2000，97，13：	1
20	Mechanisms of cardiac nerve sprouting after myocardial infarction in dogs 显示文摘	Zhou S Chen LS Chen PS	2004	Circ Res2004，95，1：	1

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