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| 1 | Clindamycin-induced acute cholestatic hepatitis显示文摘我们为牙齿的感染在 clindamycin 的管理以后在一个 42 岁的女人报导尖锐 hepatotoxicity 的一个案例。在治疗的 6 d 以后,她有疲劳,恶心,呕吐,厌食,瘙痒和黄疸。她的实验室分析显示出丙氨酸 aminotransferase (中高音) , 1795 IU/L (正常范围 0-40 ) ;aspartate aminotransferase (著名计算机生产厂商) , 1337 IU/L (正常范围 5-34 ) ;硷性磷酸酯酶(高山) , 339 IU/L (正常范围 40-150 ) ;gamma-glutamyl transpeptidase (GGT ) , 148 IU/L (正常范围 9-64 IU/L ) ;全部的胆红素, 4.1 mg/dL;直接胆红素, 2.9 mg/dL 和前凝血酶时间(磅) , 13.5 s 与国际规范的比率(INR ) , 1.04。她被就医,与立即的药中止。她的肝活体检视标本显示出混合类型(肝细胞和胆汁郁积的) 肝的损害,与导致药的肝炎的诊断兼容。用 Naranjo 概率规模的一个客观诱发性评价建议 clindamycin 是尖锐肝炎的可能的原因。在易受影响的个人, clindamycin 使用可以导致尖锐混合类型肝毒性。如果在严重肝损伤被建立以前,这药被中止,完全的恢复可能是可能的。 | Cem Aygün Orhan Kocaman Yesim Gürbüz mer Sentürk Sadettin Hülagü | 2007 | World Journal of Gastroenterology2007，13，40： | 6 |
| 2 | Mesenchymal stem cell therapy in patients with small bowel transplantation:Single center experience显示文摘AIM:To study the effects of mesenchymal stem cell(MSC) therapy on the prevention of acute rejection and graft vs host disease following small bowel transplantation.METHODS: In our transplantation center, 6 isolated intestinal transplants have been performed with MSC therapy since 2009. The primary reasons for transplants were short gut syndrome caused by surgical intestine resection for superior mesenteric artery thrombosis(n = 4), Crohn's disease(n = 1) and intestinal aganglionosis(n = 1). Two of the patients were children. At the time of reperfusion, the first dose of MSCs cultured from the patient's bone marrow was passedinto the transplanted intestinal artery at a dose of 1000000 cells/kg. The second and third doses of MSCs were given directly into the mesenteric artery through the arterial anastomosis using an angiography catheter on day 15 and 30 post-transplant.RESULTS: The median follow-up for these patients was 10.6 mo(min: 2 mo-max: 30 mo). Three of the patients developed severe acute rejection. One of these patients did not respond to bolus steroid therapy. Although the other two patients did respond to antirejection treatment, they developed severe fungal and bacterial infections. All of these patients died in the 2nd and 3rd months post-transplant due to sepsis. The remaining patients who did not have acute rejection had good quality of life with no complications observed during the follow-up period. In addition, their intestinal grafts were functioning properly in the 13th, 25th and 30th month post-transplant. The patients who survived did not encounter any problems related to MSC transplantation.CONCLUSION: Although this is a small case series and not a randomized study, it is our opinion that small bowel transplantation is an effective treatment for intestinal failure, and MSC therapy may help to prevent acute rejection and graft vs host disease following intestinal transplantation. | Sait Murat Do?an Sel?uk K?l?n? Eyüp Kebap?? Cem Tu?men Mustafa ?lmez Cezmi Karaca Alp Gürkan Ma?allah Baran Yusuf Kurtulmu? | 2014 | World Journal of Gastroenterology2014，20，25： | 3 |
| 3 | Management of Recurrent Malignant Pleural Effusion with Chemical Pleurodesis显示文摘 | Dalokay Kilic Hadi Akay ?evket Kavuk?u Hakan Kutlay Ayten Kayi Cangir Serkan En?n Cem Kadilar | 2005 | Surgery Today2005，，8： | 2 |
| 4 | Vulvar syringoma exacerbated during pregnancy显示文摘 | Cem Turan Mustafa Ugur Lale Kutluay Selahattin Kükner Tülin Dabakoglu Tugrul Aydogdu Yusuf Ergün Omer Cobanoglu | 1996 | European Journal of Obstetrics and Gynecology1996，，1： | 1 |
| 5 | An investigation of the role of justice in turnover intentions, job satisfaction, and organizational citizenship behavior in hospitality industry 显示文摘 | Halil N Cem T | 2010 | International Journal of Hospitality Management2010，29，01： | 1 |
| 6 | Rheological properties of reduced-fat and low-fat ice cream containing whey protein isolate and inulin显示文摘 | Ay?e Sibel Akal?n Cem Karag?zlü Gülfem ünal | | European Food Research and Technology0，，： | 1 |
| 7 | Normal Pancreatic Exocrine Function Does Not Exclude MRI/ MRCP Chronic Pancreatitis Findings 显示文摘 | Alkaade S Cem Balci N Momtahen AJ | 2008 | J Chn Gastroenterol2008，42，8： | 1 |
| 8 | Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice显示文摘 | Furuhashi Masato Fucho Raquel G?rgün Cem Z Tuncman Gürol Cao Haiming Hotamisligil G?khan S | 2008 | Journal of Clinical Investigation2008，，7： | 1 |
| 9 | Neuroendoerine tumors of the pancreas: spectrum of appearances on MRI 显示文摘 | Semelka RC Custodio CM Cem Balci N | 2000 | J Magn Reson Imaging2000，11，： | 1 |
| 10 | Esophageal motility and 24-h pH profiles of patients with heterotopic gastric mucosa in the cervical esophagus显示文摘 | Esin Korkut Mehmet Bekta? Murat Alkan Yusuf üstün Cem Meco Ali ?zden Irfan Soykan | 2009 | European Journal of Internal Medicine2009，，1： | 1 |
| 11 | Neuroendocrine tumors of the pancreas: spectrum of appearances on MRI 显示文摘 | Semelka RC Custodio CM Cem Balci N | 2000 | J Magn Reson Imaging2000，11，2： | 1 |
| 12 | The role of low-molecular-weight heparin in recurrent implantation failure: a prospective, quasi-randomized, controlled study显示文摘 | Bülent Berker Salih Ta?k?n Korhan Kahraman Elif Aylin Ta?k?n Cem Atabeko?lu Murat S?nmezer | 2011 | Fertility and Sterility2011，，8： | 1 |
| 13 | Diagnostic Value of D-Dimer and Antithrombin-Ⅲ Levels in Predicting Prosthetic tteart Valve Thrombosis显示文摘 | Ozan K Bahattin T | 2003 | Tex Heart Inst J2003，30，： | 1 |
| 14 | Comparison of two oral contraceptive forms containing cyproterone acetate and drospirenone in the treatment of patients with polycystic ovary syndrome: a randomized clinical trial显示文摘 | Korhan Kahraman Yavuz Emre ?ükür Cem Somer Atabeko?lu Can Ate? Salih Ta?k?n ?erife Esra ?etinkaya Harun Egemen Tolunay Batuhan ?zmen Murat S?nmezer Bülent Berker | 2014 | Archives of Gynecology and Obstetrics2014，，2： | 1 |
| 15 | Allopurinol Ameliorates Thioacetamide-Induced Acute Liver Failure by Regulating Cellular Redox-Sensitive Transcription Factors in Rats显示文摘 | Ulvi Demirel Mehmet Yaln?z Cem Aygün Cemal Orhan Mehmet Tuzcu Kaz?m Sahin ?brahim Hanifi ?zercan ?brahim Halil Bah?ecio?lu | 2012 | Inflammation2012，，4： | 1 |
| 16 | Asymmetric dimethylarginine contributes to airway nitric oxide deficiency in patients with COPD显示文摘 | Aydin M Altintas N Cem ML | 2015 | Clin Respir J2015，48，4： | 1 |
| 17 | Prevention of acute radiation-induced esophagitis with glutamine in non-small cell lung cancer patients treated with radiotherapy:evaluation of clinical and dosimetric parameters显示文摘 | ERKAN T MELEK N Y CEM O | 2009 | Lung Cancer2009，63，2： | 1 |
| 18 | Short carbon fiber reinforced polycarbonate composites: Effects of different sizing materials显示文摘 | Cem O N Gamze K L Ayse A | 2014 | Composites Part B: Engineering2014，62，： | 1 |
| 19 | Is Rectal Washout Necessary in Anterior Resection for Rectal Cancer? A Prospective Clinical Study显示文摘 | Cem Terzi MD Tarkan ünek MD ?zgül Sa?ol MD Tu?bahan Y?lmaz MD Mehmet Füzün MD Selman S?kmen MD Gül Erg?r MD Ali Küpelio?lu MD | 2006 | World Journal of Surgery2006，，2： | 1 |
| 20 | Neonatal Gastric Perforation: Review of 23 Years’ Experience显示文摘 | Cem Sultan Kara Zekeriya ?l?e Sinan Celay?r Nüvit Sarimurat Ergun Erdogan Daver Yeker | 2004 | Surgery Today2004，，3： | 1 |
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