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| 1 | Contrasted continental rifting via plume-craton interaction: Applications to Central East African Rift显示文摘The East African Rift system(EARS)provides a unique system with the juxtaposition of two contrasting yet simultaneously formed rift branches,the eastern,magma-rich,and the western,magma-poor,on either sides of the old thick Tanzanian craton embedded in a younger lithosphere.Data on the pre-rift,syn-rift and post-rift far-field volcanic and tectonic activity show that the EARS formed in the context of the interaction between a deep mantle plume and a horizontally and vertically heterogeneous lithosphere under far-field tectonic extension.We bring quantitative insights into this evolution by implementing high-resolution 3D thermo-mechanical numerical deformation models of a lithosphere of realistic rheology.The models focus on the central part of the EARS.We explore scenarios of plumelithosphere interaction with plumes of various size and initial position rising beneath a tectonically pre-stretched lithosphere.We test the impact of the inherited rheological discontinuities(suture zones)along the craton borders,of the rheological structure,of lithosphere plate thickness variations,and of physical and mechanical contrasts between the craton and the embedding lithosphere.Our experiments indicate that the ascending plume material is deflected by the cratonic keel and preferentially channeled along one of its sides,leading to the formation of a large rift zone along the eastern side of the craton,with significant magmatic activity and substantial melt amount derived from the mantle plume material.We show that the observed asymmetry of the central EARS,with coeval amagmatic(western)and magmatic(eastern)branches,can be explained by the splitting of warm material rising from a broad plume head whose initial position is slightly shifted to the eastern side of the craton.In that case,neither a mechanical weakness of the contact between the craton and the embedding lithosphere nor the presence of second plume are required to produce simulations that match observations.This result reconciles the passive and active rift models and demonstrates the possibility of development of both magmatic and amagmatic rifts in identical geotectonic environments. | Alexander Koptev Evgueni Burov Eric Calais Sylvie Leroy Taras Gerya Laurent Guillou-Frottier Sierd Cloetingh | 2016 | Geoscience Frontiers2016，7，2： | 4 |
| 2 | Fluorouracil-based adjuvant chemotherapy after preoperative chemoradiotherapy in rectal cancer: long-term results of the EORTC 22921 randomised study显示文摘 | Jean-Fran?ois Bosset Gilles Calais Laurent Mineur Philippe Maingon Suzana Stojanovic-Rundic René-Jean Bensadoun Etienne Bardet Alexander Beny Jean-Claude Ollier Michel Bolla Dominique Marchal Jean-Luc Van Laethem Vincent Klein Jordi Giralt Pierre Clavère | 2014 | Lancet Oncology2014，，2： | 2 |
| 3 | PET/CT在前列腺癌放疗规划中的应用显示文摘放疗及根治性前列腺切除术是局限性前列腺癌的最终治疗选择。根治性前列腺切除术后前列腺特异抗原水平升高提示前列腺癌复发,此类患者仍可通过挽救性放疗治愈。为了使治愈机会最大化,放疗靶区应包括疾病的所有范围。因此,无论是根治性还是挽救性放疗,准确估计疾病位置对放疗规划至关重要。目前一线显像方法对前列腺癌的早期分期和生化复发的检测灵敏度均有限。将PET纳入前列腺癌患者的常规评估可以提高分期的准确性和放疗计划的规范性。目前,18F-脱氧葡萄糖(FDG)PET/CT已被常规用于多种癌症的放疗规划,但其对前列腺癌的灵敏度较低。其他评估前列腺癌的PET探针包括18F-NaF、11C-乙酸盐、11C或18F标记的胆碱、抗1-氨基酸-3-18F-氟环丁烷-1羧酸(18F-fluciclovine)和68Ga或18F标记的配体,均可与前列腺特异膜抗原(PSMA)结合。PSMA似乎是最灵敏和特异的配体,但其尚未获得美国食品与药品监督管理局(FDA)的新药申请批准。回顾性和前瞻性研究显示,PET/CT对前列腺放疗计划可能有潜在的重要价值。将患者随机分配到常规放疗计划与PET/CT辅助放疗计划的前瞻性试验或许可以得出很有意义的临床结果。目前正在进行前瞻性临床试验,评估利用18F-fluciclovine PET/CT对具有临床终点的挽救性放疗进行规划;建议进行前瞻性试验,评估PSMA PET/CT对前列腺放疗计划的临床影响。 | 李冠男(译) 李林(审校) Jeremie Calais Minsong Cao Nicholas G.Nickols | 2020 | 中华核医学与分子影像杂志2020，40，9： | 2 |
| 4 | Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance显示文摘 | Ling Yang Ping Li Suneng Fu Ediz S. Calay G?khan S. Hotamisligil | 2010 | Cell Metabolism2010，，6： | 2 |
| 5 | Intermittent Androgen Deprivation for Locally Advanced and Metastatic Prostate Cancer: Results from a Randomised Phase 3 Study of the South European Uroncological Group显示文摘 | Fernando E.C. Calais da Silva Aldo V. Bono Peter Whelan Maurizio Brausi Anton Marques Queimadelos Jose A. Portillo Martin Ziya Kirkali Fernando M.V. Calais da Silva Chris Robertson | 2009 | European Urology2009，，6： | 2 |
| 6 | Chemotherapy with preoperative radiotherapy in rectal cancer显示文摘 | Bosset JF Collette L Calais G | | New England Journal of Medicine0，，： | 2 |
| 7 | Multilevel Converters Single-phase Grid Connected Photovoltaic System显示文摘 | Agelidis V G Meinhardt M | 1999 | Solar Energy1999，66，5： | 1 |
| 8 | Transpressional rupture of an unmapped fault during the 2010 Haiti earthquake显示文摘 | Calais E Freed A Mattioli G | 2010 | Nature Geo~cience2010，3，11： | 1 |
| 9 | Crustal strain in the Southern Alps,France, 1948-1998显示文摘 | Calais E Gallsson L Stephan J F | 2000 | Tectonophysics2000，319，： | 1 |
| 10 | Multilevel converters single-phase grid converter for photovohaic system 显示文摘 | Calais M Agelidis V G Meinhardt M | 1999 | Solar energy1999，66，5： | 1 |
| 11 | Chemotherapy with preoperative radiotherapy in rectal cancer 显示文摘 | Bosset JF Collette L Calais G | 2006 | N Engl J Med2006，355，11： | 1 |
| 12 | Interseismie plate coupling and strain partitioning in the northeastern Caribbe- an 显示文摘 | Manaker D M Calais E Freed A M | 2008 | Geophysical Journal International2008，174，3： | 1 |
| 13 | Chemotherapy with preoperative radiotherapy in rectal caneer显示文摘 | Bosset JF Collette L Calais G | 2006 | N Engl J Med2006，355，11： | 1 |
| 14 | Chemotherapy withpreoperative radiotherapy in rectal cancei显示文摘 | Bosset JF Collette L Calais G et a/ | 2006 | N Engl J Med2006，355，11： | 1 |
| 15 | The Incidence of placental abnormalities,maternal and cord plasma malondialdehyde and vascular endothelial growth factor levels in women with gestational diabetes mellitus and nondiabetic controls 显示文摘 | Madazl R Tuten A Calay Z | 2008 | Gynecol Obstet Invest2008，65，4： | 1 |
| 16 | Chemotherapy with preoperative radiotherapy in rectal cancer显示文摘 | Bosset JF Collette L Calais G | 2006 | N Engl J Med2006，355，11： | 1 |
| 17 | Apoptosis in the placenta of pregnancies complicated with IUGR 显示文摘 | Erel CT Dane B Calay Z | 2001 | Int J Gynaecol Obstet2001，73，： | 1 |
| 18 | Automatic orbit quality control for near real-time GPS zenith tropospheric delay estimation显示文摘 | Ge M Calais E Haase J | | 0，，： | 1 |
| 19 | Skin-to-skin contact of fullterm infants : an explorative study of promoting and hin- dering factors in two Nordic childbirth settings 显示文摘 | Calais E Dalbye R Nyqvist KH | 2010 | Acta Paediatr2010，99，7： | 1 |
| 20 | Randomized trial of radiation therapy versus concomitant chemoradiotherapy and radiation therapy for advanced-stage oropharynx carcinoma显示文摘 | Alfonsi M Bardet E | 1999 | J Natl Cancer Inst1999，91，： | 1 |
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