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| 1 | Service-aware 6G:An intelligent and open network based on the convergence of communication,computing and caching显示文摘With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular networks(5G).The future sixth generation of mobile cellular networks(6G)is expected to have the capability to support new and unknown services with changing requirements.Hence,in addition to enhancing its capability by 10–100 times compared with 5G,6G should also be intelligent and open to adapt to the ever-changing services in the IoT,which requires a convergence of Communication,Computing and Caching(3C).Based on the analysis of the requirements of new services for 6G,this paper identifies key enabling technologies for an intelligent and open 6G network,all featured with 3C convergence.These technologies cover fundamental and emerging topics,including 3C-based spectrum management,radio channel construction,delay-aware transmission,wireless distributed computing,and network self-evolution.From the detailed analysis of these 3C-based technologies presented in this paper,we can see that although they are promising to enable an intelligent and open 6G,more efforts are needed to realize the expected 6G network. | Yiqing Zhou Ling Liu Lu Wang Ning Hui Xinyu Cui Jie Wu Yan Peng Yanli Qi Chengwen Xing | 2020 | Digital Communications and Networks2020，6，3： | 57 |
| 2 | Paleoproterozoic volcanic rocks in the southern margin of the North China Craton, central China:Implications for the Columbia supercontinent显示文摘The volcanic rocks of the Xiong’er Group are situated in the southern margin of the North China Craton(NCC).Research on the Xiong er Group is important to understand the tectonic evolution of the NCC and the Columbia supercontinent during the Paleoproterozoic.In this study,to constrain the age of the Xiong’er volcanic rocks and identify its tectonic environment,we report zircon LA-ICP-MS data with Hf isotope,whole-rock major and trace element compositions and Sr-Nd-Pb-Hf isotopes of the volcanic rocks of the Xiong’er Group.The Xiong’er volcanic rocks mainly consist of basaltic andesite,andesite.dacite and rhyolite,with minor basalt.Our new sets of data combined with those from previous studies indicate that Xiong’er volcanism should have lasted from 1827 Ma to 1746 Ma as the major phase of the volcanism.These volcanics have extremely low MgO.Cr and Ni contents,are enriched in LREEs and LILEs but depleted in HFSEs(Nb,Ta,and Ti),similar to arc-related volcanic rocks.They are characterized by negative zirconεHft values of-17.4 to 8.8,whole-rock initial 87Sr/86Sr values of 0.7023 to 0.7177 andεNd(t)values of-10.9 to 6.4.and Pb isotopes(206Pb/204Pb=14.366-16.431,207Pb/204Pb=15.106-15.371,208Pb/204Pb=32.455-37.422).The available elemental and Sr-Nd-Pb-Hf isotope data suggest that the Xiong’er volcanic rocks were sourced from a mantle contaminated by continental crust.The volcanic rocks of the Xiong’er Group might have been generated by high-degree partial melting of a lithospheric mantle that was originally modified by oceanic subduction in the Archean.Thus,we suggest that the subduction-modified lithospheric mantle occurred in an extensional setting during the breakup of the Columbia supercontinent in the Late Paleoproterozoic,rather than in an arc setting. | Changming Wang Xinyu He Emmanuel John M. Carranza Chengmin Cui | 2019 | Geoscience Frontiers2019，10，4： | 14 |
| 3 | Optimization and test for spraying parameters of cotton defoliant sprayer显示文摘Boom sprayer is widely used in large farm crops because of its high working efficiency and favorable spraying effect.But there are still some problems in cotton defoliant spraying in Xinjiang,China.Cotton is planted in a high density in Xinjiang,the row space is(10+66)cm,leaves in two adjacent rows are seriously overlapped,the lower leavers are poorly sprayed,so the defoliation effect is poor,and the cotton quality is degraded.To solve this problem and improve the defoliant droplets coverage on the cotton canopy,the original boom spraying was modified,and the spraying pardameters was optimized by the central combination test and design concept of Box-Behnken based on a single-factor test.A quadratic polynomial model of droplets coverage was created by using working parameters including horizontal spraying boom height,hang boom height and nozzles angle as the influential factors and the mean droplets coverage on cotton canopy as the target function,and the effectiveness of mode and interaction of factors were analyzed.The model was optimized and analyzed using the regression analysis method and response surface analysis method of software Design-Expert 7.0.0,and the optimal combination of spraying parameters was obtained.The results showed that the droplets coverage on cotton canopy were influenced by boom height,sprayer height and angled nozzles sequentially from large to small,and the optimal combination of spraying parameters was under horizontal spraying boom height of 134 cm,hang spraying boom height of 27.5 cm and nozzles angle of 21°.The mean droplets coverage of experimental value and predicted value on cotton canopy were 19.6%and 20.43%respectively in such conditions,and the relative error to the estimated value on the model was–4.25%.The research result can provide a reference for further optimizing the spraying parameters of cotton defoliant sprayer. | Qin Weicai Xue Xinyu Cui Longfei Zhou Qingqing Xu Zhufeng Chang Feilong | 2016 | International Journal of Agricultural and Biological Engineering2016，9，4： | 9 |
| 4 | Immobilization of functional nano-objects in living engineered bacterial biofilms for catalytic applications显示文摘Nanoscale objects feature very large surface-area-to-volume ratios and are now understood as powerful tools for catalysis,but their nature as nanomaterials brings challenges including toxicity and nanomaterial pollution.Immobilization is considered a feasible strategy for addressing these limitations.Here,as a proof-of-concept for the immobilization of nanoscale catalysts in the extracellular matrix of bacterial biofilms,we genetically engineered amyloid monomers of the Escherichia coli curli nanofiber system that are secreted and can self-assemble and anchor nano-objects in a spatially precise manner.We demonstrated three scalable,tunable and reusable catalysis systems:biofilm-anchored gold nanoparticles to reduce nitro aromatic compounds such as the pollutant p-nitrophenol,biofilm-anchored hybrid Cd0.9Zn0.1S quantum dots and gold nanoparticles to degrade organic dyes and biofilm-anchored CdSeS@ZnS quantum dots in a semi-artificial photosynthesis system for hydrogen production.Our work demonstrates how the ability of biofilms to grow in scalable and complex spatial arrangements can be exploited for catalytic applications and clearly illustrates the design utility of segregating high-energy nano-objects from injury-prone cellular components by engineering anchoring points in an extracellular matrix. | Xinyu Wang Jiahua Pu Yi Liu Fang Ba Mengkui Cui Ke Li Yu Xie Yan Nie Qixi Mi Tao Li Lingli Liu Manzhou Zhu Chao Zhong | 2019 | National Science Review2019，6，5： | 9 |
| 5 | Optimized design and test for a pendulum suspension of the crop spray boom in dynamic conditions based on a six DOF motion simulator显示文摘Spray deposit distribution from a field sprayer is mainly affected by the boom movements when the tractor is driven over a rough soil surface,the pendulum suspension that used to reduce and control the movement of spray boom by isolating the boom from vibrations of the tractor will directly enhance uniform deposition of chemicals.However,how to match the parameters of the suspension with the properties of the boom is the key problem.The dynamic rigid-flexible coupling model of the virtual prototype of the spray boom suspension system was established by using ADAMS and ABAQUS software.An optimization of the suspension parameters for a large spay boom was carried out based on the optimal Latin hypercube design,radial basis function neural network,and multi-objective genetic algorithm NSGA-II.After modified parameters of the suspension,the travel of the sprayer on a typical field motion track was simulated based on a six DOF motion simulator,and the dynamic behavior of the boom suspension was measured.The results show that RMS of the measured boom roll angle and the boom center displacement for optimized solution were reduced by 14.76%and 12.43%compared with the original suspension.Finally,the inertial measurement unit(IMU)was used to measure the movements of the sprayer vehicle during the pesticide application on the Hongze Lake Farm,the experiment of field condition reproduced by using the six DOF motion simulator,the standard deviation of the roll angle and vibration displacement for the optimized sprayer boom are only 0.6382°and 62.279 mm respectively.The research provides theoretical basis and experimental method for parameter optimization of large scale boom suspension. | Longfei Cui Hanping Mao Xinyu Xue Suming Ding Baiyu Qiao | 2018 | International Journal of Agricultural and Biological Engineering2018，11，3： | 9 |
| 6 | The heterogeneity of islet autoantibodies and the progression of islet failure in type 1 diabetic patients显示文摘Type 1 diabetes mellitus is heterogeneous in many facets. The patients suffered from type 1 diabetes present several levels of islet function as well as variable number and type of islet-specific autoantibodies. This study was to investigate prevalence and heterogeneity of the islet autoantibodies and clinical phenotypes of type 1 diabetes mellitus; and also discussed the process of islet failure and its risk factors in Chinese type 1 diabetic patients. A total of 1,291 type 1 diabetic patients were enrolled in this study. Demographic information was collected. Laboratory tests including mixed-meal tolerance test, human leukocyte antigen alleles, hemoglobin A1 c, lipids, thyroid function and islet autoantibodies were conducted. The frequency of islet-specific autoantibody in newly diagnosed T1 DM patients(duration shorter than half year) was 73% in East China. According to binary logistic regressions, autoantibody positivity, longer duration and lower Body Mass Index were the risk factors of islet failure. As the disease developed, autoantibodies against glutamic acid decarboxylase declined as well as the other two autoantibodies against zinc transporter 8 and islet antigen 2. The decrease of autoantibodies was positively correlated with aggressive beta cell destruction. Autoantibodies can facilitate the identification of classic T1 DM from other subtypes and predict the progression of islet failure. As there were obvious heterogeneity in autoantibodies and clinical manifestation in different phenotypes of the disease, we should take more factors into consideration when identifying type 1 diabetes mellitus. | Jin Liu Lingling Bian Li Ji Yang Chen Heng Chen Yong Gu Bingqin Ma Wei Gu Xinyu Xu Yun Shi Jian Wang Dalong Zhu Zilin Sun Jianhua Ma Hui Jin Xing Shi Heng Miao Bing Xin Yan Zhu Zhenwen Zhang Ruifang Bu Lan Xu Guangde Shi Wei Tang Wei Li Dongmei Zhou Jun Liang Xingbo Cheng Bimin Shi Jixiang Dong Ji Hu Chen Fang Shao Zhong Weinan Yu Weiping Lu Chenguang Wu Li Qian Jiancheng Yu Jialin Gao Xiaoqiang Fei Qingqing Zhang Xueqin Wang Shiwei Cui Jinluo Cheng Ning Xu Guofeng Wang Guoqing Han Chunrong Xu Yun Xie Minmin An Wei Zhang Zhixiao Wang Yun Cai Qi Fu Yu Fu Shuai Zheng Fan Yang Qingfang Hu Hao Dai Yu Jin Zheng Zhang Kuanfeng Xu Yifan Li Jie Shen Hongwen Zhou Wei He Xuqin Zheng Xiao Han Liping Yu Jinxiong She Mei Zhang Tao Yang | 2016 | Science China(Life Sciences)2016，59，9： | 5 |
| 7 | Evaluation of COC183B2 antibody targeting ovarian cancer by near-infrared fluorescence imaging显示文摘Objective: To evaluate the imaging potential of a novel near-infrared(NIR) probe conjugated to COC183 B2 monoclonal antibodies(MAb) in ovarian cancer(OC).Methods: The expression of OC183 B2 antigen in OC was determined by immunohistochemical(IHC) staining using tissue microarrays with the H-score system and immunofluorescence(IF) staining of tumor cell lines.Imaging probes with the NIR fluorescent dye cyanine 7(Cy7) conjugated to COC183 B2 Mab were chemically engineered. OC183 B2-positive human OC cells(SKOV3-Luc) were injected subcutaneously into BALB/c nude mice. Bioluminescent imaging(BLI) was performed to detect tumor location and growth. COC183 B2-Cy7 at 1.1,3.3, 10, or 30 μg were used for in vivo fluorescence imaging, and phosphate-buffered saline(PBS), free Cy7 dye and mouse isotype immunoglobulin G(IgG)-Cy7(delivered at the same doses as COC183 B2-Cy7) were used as controls.Results: The expression of OC183 B2 with a high H-score was more prevalent in OC tissue than fallopian tube(FT) tissue. Among 417 OC patients, the expression of OC183 B2 was significantly correlated with the histological subtype, histological grade, residual tumor size, relapse state and survival status. IF staining demonstrated that COC183 B2 specifically expressed in SKOV3 cells but not HeLa cells. In vivo NIR fluorescence imaging indicated that COC183 B2-Cy7 was mainly distributed in the xenograft and liver with optimal tumor-to-background(T/B)ratios in the xenograft at 30 μg dose. The highest fluorescent signals in the tumor were observed at 96 h postinjection(hpi). Ex vivo fluorescence imaging revealed the fluorescent signals mainly from the tumor and liver. IHC analysis confirmed that xenografts were OC183 B2 positive.Conclusions: COC183 B2 is a good candidate for NIR fluorescence imaging and imaging-guided surgery in OC. | Chen Zhang Xinyu Ling Yanxiu Guo Cunzhong Yuan Hongyan Cheng Xue Ye Ruiqiong Ma Yinli Zhang Yi Li Xiaohong Chang Beihua Kong Tao Liu Heng Cui | 2019 | Chinese Journal of Cancer Research2019，31，4： | 4 |
| 8 | A male-ABCD algorithm for hepatocellular carcinoma risk prediction in HBs Ag carriers显示文摘Objective: Hepatocellular carcinoma(HCC) development among hepatitis B surface antigen(HBs Ag) carriers shows gender disparity, influenced by underlying liver diseases that display variations in laboratory tests. We aimed to construct a risk-stratified HCC prediction model for HBs Ag-positive male adults.Methods: HBs Ag-positive males of 35-69 years old(N=6,153) were included from a multi-center populationbased liver cancer screening study. Randomly, three centers were set as training, the other three centers as validation. Within 2 years since initiation, we administrated at least two rounds of HCC screening using Bultrasonography and α-fetoprotein(AFP). We used logistic regression models to determine potential risk factors,built and examined the operating characteristics of a point-based algorithm for HCC risk prediction.Results: With 2 years of follow-up, 302 HCC cases were diagnosed. A male-ABCD algorithm was constructed including participant's age, blood levels of GGT(γ-glutamyl-transpeptidase), counts of platelets, white cells,concentration of DCP(des-γ-carboxy-prothrombin) and AFP, with scores ranging from 0 to 18.3. The area under receiver operating characteristic was 0.91(0.90-0.93), larger than existing models. At 1.5 points of risk score,26.10% of the participants in training cohort and 14.94% in validation cohort were recognized at low risk, with sensitivity of identifying HCC remained 100%. At 2.5 points, 46.51% of the participants in training cohort and 33.68% in validation cohort were recognized at low risk with 99.06% and 97.78% of sensitivity, respectively. At 4.5 points, only 20.86% of participants in training cohort and 23.73% in validation cohort were recognized at high risk,with positive prediction value of 22.85% and 12.35%, respectively.Conclusions: Male-ABCD algorithm identified individual's risk for HCC occurrence within short term for their HCC precision surveillance. | Yuting Wang Minjie Wang He Li Kun Chen Hongmei Zeng Xinyu Bi Zheng Zhu Yuchen Jiao Yong Wang Jian Zhu Hui Zhao Xiang Liu Chunyun Dai Chunsun Fan Can Zhao Deyin Guo Hong Zhao Jianguo Zhou Dongmei Wang Zhiyuan Wu Xinming Zhao Wei Cui Xuehong Zhang Jianqiang Cai Wanqing Chen Chunfeng Qu | 2021 | Chinese Journal of Cancer Research2021，33，3： | 3 |
| 9 | Design and experiment of electro hydraulic active suspension for controlling the rolling motion of spray boom显示文摘Boom sprayer is one of the most commonly used plant protection machinery for spraying pesticide.Studies have shown that the efficiency of chemicals is highly correlated with the uniformity of spray distribution patterns.As the boom is a large and flexible structure,boom rolling leads to overlapping and leakage of the pesticides.In order to improve spray uniformity,the boom attitude should be kept parallel to the ground slope or to the crop canopy beneath the boom.Passive suspension can attenuate frequencies above its resonance frequency,but nothing can be done to align the boom to the sloping ground.Therefore,an active suspension system is designed,which includes DSP-based controller,a servo valve,a hydraulic cylinder,two ultrasonic sensors,one inertial attitude sensor,and the developed control procedures.In order to prevent the wrong response of the control system caused by the high frequency component due to uneven crop canopy or rough ground.A special signal processing algorithm was proposed,including the limiting filter,smoothing algorithm and data fusion algorithm based on optimal weight.The transient and steady-state performances of the boom control system using velocity feedforward PID algorithm were tested on a six DOF motion simulator.It can be seen that the low-frequency tracking performance of the boom was greatly improved after the electro-hydraulic active suspension was added.At the resonance frequency,the peak angle of active suspension and passive suspensions are 0.72°and 1.29°respectively,and the resonance peak is greatly reduced.The controller was implemented on a self-propelled boom sprayer and validated under field conditions,the standard deviation of the roll angle of the boom with active suspension is 0.40°,compared with 1.04°of the sprayer chassis.Experimental results show that the active suspension control system can effectively reduce the effect of ground excitation disturbance on the application process,and has good tracking performance for low frequency terrain change. | Longfei Cui Xinyu Xue Feixiang Le Hanping Mao Suming Ding | 2019 | International Journal of Agricultural and Biological Engineering2019，12，4： | 3 |
| 10 | Microstructure and bioactivity of a cold sprayed rough/porous Ta coating on Ti6Al4V substrate显示文摘To improve the bioactivity and biocompatibility of titanium implants,a rough/porous tantalum(Ta)coating was firstly prepared on Ti6Al4V substrate by cold spraying.The results indicated that the surface of Ta coating is extremely rough with lots of visible holes,because of poor deposition quality.Microstructure and microhardness results showed that different layers appeared in the inner and outer parts of coatings,corresponding to porosity,due to lack of subsequent compaction.The simulated body fluid(SBF)soaking test showed that spherical apatite sediments were mineralized on rough/porous surface in SBF after 2–4 weeks,which demonstrated that the cold sprayed Ta coating had good bioactivity.This was mainly attributed to the rough/porous surface of Ta coating obtained by cold spraying,which is conducive to the heterogeneous nucleation of apatite on it. | TANG JunRong ZHAO ZhiPo CUI XinYu WANG JiQiang XIONG TianYing | 2020 | Science China(Technological Sciences)2020，63，5： | 3 |
| 11 | GOLM1 restricts colitis and colon tumorigenesis by ensuring Notch signaling equilibrium in intestinal homeostasis显示文摘Intestinal epithelium serves as the first barrier against the infections and injuries that mediate colonic inflammation.Colorectal cancer is often accompanied with chronic inflammation.Differed from its well-known oncogenic role in many malignancies,we present here that Golgi membrane protein 1(G0LM1,also referred to as GP73)suppresses colorectal tumorigenesis via maintenance of intestinal epithelial barrier.G0LM1 deficiency in mice conferred susceptibility to mucosal inflammation and colitis-induced epithelial damage,which consequently promoted colon cancer.Mechanistically,depletion of G0LM1 in intestinal epithelial cells(lECs)led to aberrant Notch activation that interfered with IEC differentiation,maturation,and lineage commitment in mice.Pharmacological inhibition of Notch pathway alleviated epithelial lesions and restrained pro-tumorigenic inflammation in G0LM1-deficient mice.Therefore,G0LM1 maintains IEC homeostasis and protects against colitis and colon tumorigenesis by modulating the equilibrium of Notch signaling pathway. | Yang Pu Ya Song Mengdi Zhang Caifeng Long Jie Li Yanan Wang Yinzhe Xu Fei Pan Na Zhao Xinyu Zhang Yanan Xu Jianxin Cui Hongying Wang Yan Li Yong Zhao Di Jin Hongbing Zhang | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 2 |
| 12 | Multi-Hop Routing Optimization Method Based on Improved Ant Algorithm for Vehicle to Roadside Network显示文摘 | Hao Dong Xiaohui Zhao Liangdong Qu Xuefen Chi Xinyu Cui | 2014 | Journal of Bionic Engineering2014，11，3： | 2 |
| 13 | A micro-nano optogenetic system based on probiotics for in situ host metabolism regulation显示文摘Genetically engineered bacteria have aroused attention as micro-nano drug delivery systems in situ.However,conventional designs of engineered bacteria usually function constantly or autonomously,which might be non-specific or imprecise.Therefore,designing and optimizing in situ control strategy are important methodological progress for therapeutic researches of intestinal engineered bacteria.Here,a micro-nano optogenetic system based on probiotic was developed combining microelectronics,nanotechnology,and synthetic biology to achieve in situ controllable drug delivery.Firstly,optogenetic engineered Lactococcus lactis was orally administrated in the intestinal tract.A wearable optical device was designed to control optical signals remotely.Then,L.lactis could be customized to secrete peptides according to optical signals.As an example,optogenetic L.lactis system can be constructed to secrete glucagon-like peptide-1(GLP-1)under the control of the wearable optical device to regulate metabolism.To improve the half-life of GLP-1 in vivo,Fc-domain fused GLP-1 was optimally used.Using this strategy,blood glucose,weight,and other features were well controlled in rats and mice models.Furthermore,upconversion microcapsules were introduced to increase the excitation wavelength of the optogenetic system for better penetrability.This strategy has biomedical potential to expand the toolbox for intestinal engineered bacteria. | Xinyu Zhang Ning Ma Wei Ling Gaoju Pang Tao Sun Jing Liu Huizhuo Pan Meihui Cui Chunli Han Chun Yang Jin Chang Xian Huang Hanjie Wang | 2023 | Nano Research2023，16，2： | 2 |
| 14 | Vehicle emissions of primary air pollutants from 2009 to 2019 and projection for the 14th Five-Year Plan period in Beijing, China显示文摘Over the past decade,the emission standards and fuel standards in Beijing have been upgraded twice,and the vehicle structure has been improved by accelerating the elimination of 2.95 million old vehicles.Through the formulation and implementation of these policies,the emissions of carbon monoxide(CO),volatile organic compounds(VOCs),nitrogen oxides(NO_(x)),and fine particulate matter(PM_(2.5))in 2019 were 147.9,25.3,43.4,and 0.91 kton in Beijing,respectively.The emission factor method was adopted to better understand the emissions characteristics of primary air pollutants from combustion engine vehicles and to improve pollution control.In combination with the air quality improvement goals and the status of social and economic development during the 14th Five-Year Plan period in Beijing,different vehicle pollution control scenarios were established,and emissions reductions were projected.The results show that the emissions of four air pollutants(CO,VOCs,NO_(x),and PM_(2.5))fromvehicles in Beijing decreased by an average of 68% in 2019,compared to their levels in 2009.The contribution of NOx emissions from diesel vehicles increased from 35% in 2009 to 56% in 2019,which indicated that clean and energy-saving diesel vehicle fleets should be further improved.Electric vehicle adoption could be an important measure to reduce pollutant emissions.With the further upgrading of vehicle structure and the adoption of electric vehicles,it is expected that the total emissions of the four vehicle pollutants can be reduced by 20%-41% by the end of the 14th Five-Year Plan period. | Tongran Wu Yangyang Cui Aiping Lian Ye Tian Renfei Li Xinyu Liu Jing Yan Yifeng Xue Huan Liu Bobo Wu | 2023 | Journal of Environmental Sciences2023，，2： | 1 |
| 15 | Characteristics of porosity and permeability layer of fossil Halimeda reef mineral rock of Miocene in the Xisha Islands and its genetic model显示文摘Halimeda is one of the major reef-building algas in the middle Miocene of Xisha, and one of the significant reefbuilding algas in the algal reef oil and gas field of the South China Sea. However, there have been few reports regarding the characteristics of mineral rocks, reservoir porosity and permeability layers, and sedimentationdiagenetic-evolution of fossil Halimeda systems. The present paper briefly introduces the relevant studies on chlorophyta Halimeda and the research status of oil and gas exploration. Through the 1 043 m core of the Xichen-1 well, we studied the characteristics of the mineral rocks and porosity and permeability of the middle Miocene Halimeda of the Yongle Atoll, identified and described the segments of fossil Halimeda, and pointed out that most of the segment slides are vertical sections in ovular, irregular or long strips. The overwhelming majority of these fossil Halimeda found and studied are vertical sections instead of cross sections. In this paper, knowledge regarding the cross sections of fossil Halimeda is reported and proven to be similar with the microscopic characteristics of modern living Halimeda; fossil Halimeda are buried in superposition; it is shown that there are different structures present, including typical bio-segment structure, and due to its feature of coexisting with red alga, tying structure, twining structure and encrusting structure are all present; and finally, it is suggested to classify the fossil Halimeda into segment algal reef dolomites. In addition, all of the studied intervals are moderately dolomitized. Secondary microcrystalline-dolosparite dominates the original aragonite raphide zones,and aphanitic-micrite dolomite plays the leading role in the cortexes and medullas; in the aragonite raphide zones between medulla and cysts, secondary dissolved pores and intercrystalline pores are formed inside the segments, and algal frame holes are formed between segments; therefore, a pore space network system(dissolved pores + intragranular dissolved pores—intercrystalline pores + algal frame holes) is established. Segment Halimeda dolomite has a porosity of 16.2%–46.1%, a permeability of 0.203×10–3–2 641×10–3 μm2, and a throatradius of 23.42–90.43 μm, therefore it is shown to be a good oil and gas reservoir. For the reasons mentioned above, we suggest building the neogene organic reef-modern reef sedimentation-diagenetic-evolution models for the Xisha Islands. | XU Hong ZHU Yurui EBERLI G.P. LUO Wei ZHAO Xinwei CAI Ying LIU Xinyu YAN Guijing ZHANG Bolin WEI Kai CUI Ruyong | 2015 | Acta Oceanologica Sinica2015，34，4： | 1 |
| 16 | Isoflavone Reduces Body Weight by Decreasing Food Intake in Ovariectomized Rats显示文摘 | Zhang Yunbo Na Xiaolin Zhang Yang Li Lina Zhao Xinyu Cui Hongbin | 2009 | Annals of Nutrition & Metabolism2009，，： | 1 |
| 17 | ESCRT-Ⅲ component OsSNF7.2 modulates leaf rolling by trafficking and endosomal degradation of auxin biosynthetic enzyme OsYUC8 in rice显示文摘The endosomal sorting complex required for transport(ESCRT)is highly conserved in eukaryotic cells and plays an essential role in the biogenesis of multivesicular bodies and cargo degradation to the plant vacuole or lysosomes.Although ESCRT components affect a variety of plant growth and development processes,their impact on leaf development is rarely reported.Here,we found that OsSNF7.2,an ESCRT-Ⅲ component,controls leaf rolling in rice(Oryza sativa).The Ossnf7.2 mutant rolled leaf 17(rl17)has adaxially rolled leaves due to the decreased number and size of the bulliform cells.OsSNF7.2is expressed ubiquitously in all tissues,and its protein is localized in the endosomal compartments.OsSNF7.2 homologs,including OsSNF7,OsSNF7.3,and OsSNF7.4,can physically interact with OsSNF7.2,but their single mutation did not result in leaf rolling.Other ESCRT complex subunits,namely OsVPS20,OsVPS24,and OsBRO1,also interact with OsSNF7.2.Further assays revealed that OsSNF7.2 interacts with OsYUC8 and aids its vacuolar degradation.Both Osyuc8and rl17 Osyuc8 showed rolled leaves,indicating that OsYUC8 and OsSNF7.2 function in the same pathway,conferring leaf development.This study reveals a new biological function for the ESCRT-Ⅲcomponents,and provides new insights into the molecular mechanisms underlying leaf rolling. | Liang Zhou Saihua Chen Maohong Cai Song Cui Yulong Ren Xinyue Zhang Tianzhen Liu Chunlei Zhou Xin Jin Limin Zhang Minxi Wu Shuyi Zhang Zhijun Cheng Xin Zhang Cailin Lei Qibing Lin Xiuping Guo Jie Wang Zhichao Zhao Ling Jiang Shanshan Zhu Jianmin Wan | 2023 | Journal of Integrative Plant Biology2023，65，6： | 1 |
| 18 | Auxin signaling module OsSK41-OsIAA10-OsARF regulates grain yield traits in rice显示文摘Auxin is an important phytohormone in plants, and auxin signaling pathways in rice play key roles in regulating its growth, development, and productivity. To investigate how rice grain yield traits are regulated by auxin signaling pathways and to facilitate their application in rice improvement, we validated the functional relationships among regulatory genes such as OsIAA10, OsSK41, and OsARF21 that are involved in one of the auxin(OsIAA10) signaling pathways. We assessed the phenotypic effects of these genes on several grain yield traits across two environments using knockout and/or overexpression transgenic lines.Based on the results, we constructed a model that showed how grain yield traits were regulated by OsIAA10 and OsTIR1, OsAFB2, and OsSK41 and OsmiR393 in the OsSK41-OsIAA10-OsARF module and by OsARF21 in the transcriptional regulation of downstream auxin response genes in the OsSK41-OsIAA10-OsARF module. The population genomic analyses revealed rich genetic diversity and the presence of major functional alleles at most of these loci in rice populations. The strong differentiation of many major alleles between Xian/indica and Geng/japonica subspecies and/or among modern varieties and landraces suggested that they contributed to improved productivity during evolution and breeding. We identified several important aspects associated with the genetic and molecular bases of rice grain and yield traits that were regulated by auxin signaling pathways.We also suggested rice auxin response factor(OsARF) activators as candidate target genes for improving specific target traits by overexpression and/or editing subspecies-specific alleles and by searching and pyramiding the ‘best' gene allelic combinations at multiple regulatory genes in auxin signaling pathways in rice breeding programs. | Fuying Ma Fan Zhang Yu Zhu Dengyong Lan Peiwen Yan Ying Wang Zejun Hu Xinwei Zhang Jian Hu Fuan Niu Mingyu Liu Shicong He Jinhao Cui Xinyu Yuan Ying Yan Shujun Wu Liming Cao Hongwu Bian Jinshui Yang Zhikang Li Xiaojin Luo | 2023 | Journal of Integrative Plant Biology2023，65，7： | 1 |
| 19 | Preparation of bioactive Ti and its alloys via electrochemical treatment in sulfuric acid solution显示文摘 | Xinyu CUI Hyun-Min KIM | 2008 | Journal of the Ceramic Society of Japan2008，116，2： | 1 |
| 20 | Uniform Persistence and Global Attractivity for Nonautonomous Competitive Systems with Nonlinear Dispersion and Delays显示文摘 | Song Xinyu Jing'an Cui | 2003 | Appl Math Comp2003，146，： | 1 |
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