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	题名	作者	年代	出处	被引量
1	Positron emission tomography scanning in the evaluation of hepatocellular carcinoma显示文摘	M.Akram Khan Connie S Combs Elizabeth M Brunt Val J Lowe Michael K Wolverson Harvey Solomon Brian T Collins Adrian M.Di Bisceglie	2000	Journal of Hepatology2000，，5：	2
2	A contactless biometric system using multiple hand features 显示文摘	MICHAEL G K O CONNIE T TEOH A B J	2012	Journal of Visual Communication and Image Representation2012，23，7：	1
3	A contactless biometric system using multiple hand features 显示文摘	MICHAEL G K O CONNIE T TEOH A B J	2012	Journal of Visual Communication and Image Representation2012，23，7：	1
4	Touch-less palm print biometrics: Novel design and implementation 显示文摘	MICHAEL G K O CONNIE T TEOH A B J	2008	Image and Vision Computing2008，26，12：	1
5	A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice 显示文摘	Satoko T Connie LM Bobby M	2011	Human Molecular Genetics2011，20，5：	1
6	Personal recognition using multi-angles gait sequences显示文摘	TEE Connie KAH O G M BENG J T A	2011	Communications in Computer and Information Science2011，189，2：	1
7	An automated palmprint recognition system显示文摘	Connie T Jin A T B Ong M G K	2005	Image and Vision Computing2005，23，5：	1
8	A contact- less biometric system using multiple hand features 显示文摘	MICHAEL G K O CONNIE T TEOH A B J	2012	Journal of Visual Communication and Image Representa- tion2012，23，7：	1
9	Ephrin A2 receptor targeting does not increase adenoviral pancreatic cancer transduction in vivo显示文摘AIM:To generate an adenoviral vector specifically targeting the EphA2 receptor(EphA2R) highly expressed on pancreatic cancer cells in vivo.METHODS:YSA,a small peptide ligand that binds the EphA2R with high affinity,was inserted into the HI loop of the adenovirus serotype 5 fiber knob.To further increase the specificity of this vector,binding sites for native adenoviral receptors,the coxsackie and adenovirus receptor(CAR) and integrin,were ablated from the viral capsid.The ablated retargeted adenoviral vector was produced on 293T cells.Specifi c targeting of this novel adenoviral vector to pancreatic cancer was investigated on established human pancreatic cancer cell lines.Upon demonstrating specifi c in vitro targeting,in vivo targeting to subcutaneous growing human pancreatic cancer was tested by intravenous and intraperitoneal administration of the ablated adenoviral vector.RESULTS:Ablation of native cellular binding sites reduced adenoviral transduction at least 100-fold.Insertion of the YSA peptide in the HI loop restored adenoviral transduction of EphA2R-expressing cells but not of cells lacking this receptor.YSA-mediated transduction was inhibited by addition of synthetic YSA peptide.The transduction specificity of the ablated retargeted vector towards human pancreatic cancer cells was enhanced almost 10-fold in vitro.In a subsequent in vivo study in a nude(nu/nu) mouse model however,no increased adenoviral targeting to subcutaneously growing human pancreas cancer nodules was seen upon injection into the tail vein,nor upon injection into the peritoneum.CONCLUSION:Targeting the EphA2 receptor increases specificity of adenoviral transduction of human pancreatic cancer cells in vitro but fails to enhance pancreatic cancer transduction in vivo.	Michael A van Geer Conny T Bakker Naoya Koizumi Hiroyuki Mizuguchi John G Wesseling Ronald PJ Oude Elferink Piter J Bosma	2009	World Journal of Gastroenterology2009，15，22：	1
10	Touch-less palm print biometrics: Novel design and implementation 显示文摘	MICHAEL G K O CONNIE T TEOH A B J	2008	Image and Vision Compu- ting2008，26，12：	1
11	Sequential Anaerobic-Aerobic Biodegradation of PCBs in Soil Slurry Microcosms 显示文摘	Evans B S Connie A D Klasson K T	1996	Applied Biochemistry and Biotechnology1996，57，1：	1
12	An automated palmprint recognition system显示文摘	Connie T Jin A T B Ong M G K		0，，：	1
13	Contingencies of self--worth显示文摘	Jennifer Crocker Connie T Wolfe	2001	Psychological Review2001，，3：	1
14	A contacfless biometric system using multiple hand features显示文摘	G K O Micheal T Connie A B J Teoh	2012	Journal of Visual Commu- nication and Image Representation2012，23，7：	1
15	Expenditure-based segmentation:Taiwanese tourists to Guam显示文摘	Connie Mok Iverson T J	2000	Tourism Management2000，21，2：	1
16	An automated palmprint recognition system 显示文摘	Connie T Jin A T B Ong Michael G K	2005	Image and Vision computing2005，23，5：	1
17	Positron emission tomography scanning in the evaluation of hepatocellular carcinoma显示文摘	M.Akram Khan Connie S Combs Elizabeth M Brunt Val J Lowe Michael K Wolverson Harvey Solomon Brian T Collins Adrian M.Di Bisceglie	2000	Journal of Hepatology2000，，5：	1
18	Improving quality and effi- ciency of postpartum hospital education 显示文摘	Barbara L Connie H Elizabeth T	2012	J Peri Edu2012，21，4：	1
19	Expenditure - based Segmentation; Tai - wanese Tourists to Guam显示文摘	Connie Mok Iverson T J	2000	Tourism Management2000，21，2：	1
20	Practice guidelines for acute pain management in the perioperative setting:an updated report by the American Society of Anesthesiologists Task Force on Acute Pain Management显示文摘	Apfelbaum J L Ashburm M A Connis K T	2004	Anesthesiology2004，100，6：	1

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