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| 1 | Using Statistical Downscaling to Quantify the GCM-Related Uncertainty in Regional Climate Change Scenarios: A Case Study of Swedish Precipitation显示文摘有在地区性的气候变化情形的不确定性的很多来源。当统计 downscaling 被用来获得地区性的气候变化情形时,不确定性可以在使用的模型,统计模型的技巧,和强迫的情形用于世界气候模型的世界气候从不确定性发源。与世界气候模型联系的不确定性能被基于一套不同世界气候模型在预言者并且在 downscaled 气候变化情形检验差别评估。什么时候标准化了象 CoupledModel Intercomparison 工程(CMIP2 ) 的第二个阶段那样的世界气候模型模拟,被使用,在 downscaled 变量的差别主要在模仿的气候在气候模型和自然可变性反映差别。Itis 建议估计的传播能作为与世界气候模型联系的不确定性的一项措施被拿。建议方法在瑞典在地区性的降水变化情形被用于评价 ofglobal-climate-model-related 不确定性。尽管在降水的变化的可观的传播存在,基于在整个瑞典的年度降水有全面增加的 17 世界气候模型表演源于统计 downscaling。一般增加能被归因于增加的 large-scaleprecipitation 和提高的偏午。估计的不确定性将近独立于区域。然而,有季节的依赖。为冬季的估计显示出信心的高水平,当为夏天的估计最不出现时。 | Deliang CHEN Christine ACHBERGER Jouni R■IS■NEN Cecilia HELLSTRM | 2006 | Advances in Atmospheric Sciences2006，23，1： | 9 |
| 2 | Multimodality imaging of ovarian cystic lesions: Review with an imaging based algorithmic approach显示文摘Ovarian cystic masses include a spectrum of benign, borderline and high grade malignant neoplasms. Imaging plays a crucial role in characterization and pretreatment planning of incidentally detected or suspected adnexal masses, as diagnosis of ovarian malignancy at an early stage is correlated with a better prognosis. Knowledge of differential diagnosis, imaging features, management trends and an algorithmic approach of such lesions is important for optimal clinical management. This article illustrates a multi-modality approach in the diagnosis of a spectrum of ovarian cystic masses and also proposes an algorithmic approach for the diagnosis of these lesions. | Ashish P Wasnik Christine O Menias Joel F Platt Usha R Lalchandani Deepak G Bedi Khaled M Elsayes | 2013 | World Journal of Radiology2013，5，3： | 7 |
| 3 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 4 | Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients显示文摘AIM: To determine the prevalence of hepatitis B virus (HBV) in adult human immunodeficiency virus (HIV) patients with CD4+ T-cell count less than 500/mm 3 and without antiretroviral therapy; to describe different HBV-HIV coinfection virological profiles; and to search for factors associated with HBs antigen (HBsAg) presence in these HIV positive patients.METHODS: During four months (June through September 2006), 491 patients were received in four HIV positive monitoring clinical centers in Abidjan. Inclusion criteria: HIV-1 or HIV-1 and 2 positive patients, age ≥ 18 years, CD4+ T-cell count < 500/mL and formal and signed consent of the patient. Realized blood tests included HIV serology, CD4+ T-cell count, quantitative HIV RNA load and HBV serological markers, such as HBsAg and HBc antibody (anti-HBcAb). We performed HBeAg, anti-HBe antibody (anti-HBeAb), anti-HBc IgM and quantitative HBV DNA load in HBsAg positive patients. Anti-HBsAb had been tested in HIV patients with HBsAg negative and anti-HBcAb-positive. HBV DNA was also tested in 188 anti-HBcAb positive patients with HBsAg negative status and without anti-HBsAb. Univariate analysis (Pearsonχ 2 test or Fischer exact test) and multivariate analysis (backward step-wise selection logistic regression) were performed as statistical analysis. RESULTS: Mean age of 491 patients was 36 ± 8.68 years and 73.3% were female. Type-1 HIV was found in 97% and dual-type HIV (type 1 plus type 2) in 3%. World Health Organization (WHO) clinical stage was 1, 2, 3 and 4 respectively in 61 (12.4%), 233 (47.5%), 172 (35%) and 25 patients (5.1%). Median CD4+ T-cell count was 341/mm 3 (interquartile range: 221-470). One hundred and twelve patients had less than 200 CD4+ T-cell/mm 3 . Plasma HIV-1 RNA load was elevated (≥ 5 log 10 copies/mL) in 221 patients (45%). HBsAg and anti-HBcAb prevalence was respectively 13.4% and 72.9%. Of the 66 HBsAg positive patients, 22 were inactive HBV carriers (33.3%), 21 had HBeAg positive hepatitis (31.8%) and 20 had HBeAg negative hepatitis (30.3%). HBeAg and anti-HBeAb were indeterminate in 3 of them. Occult B infection prevalence (HBsAg negative, anti-HBcAb positive, anti-HBsAb negative and detectable HBV DNA) was 21.3%. Three parameters were significantly associated with the presence of HBsAg: male [odds ratio (OR): 2.2;P = 0.005; 95% confidence interval (CI): 1.3-3.8]; WHO stage 4 (OR: 3.2;P = 0.01;95% CI: 1.3-7.9); and aspartate aminotransferase (AST) level higher than the standard (OR: 1.9;P = 0.04; 95% CI: 1.02-3.8). CONCLUSION: HBV infection prevalence is high in HIV-positive patients. HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIVpositive patients than in HIV negative ones. Parameters associated with HBsAg positivity were male gender, AIDS status and increased AST level. | Koffi Alain Attia Serge Eholié Eugène Messou Christine Danel Sandrine Polneau Henri Chenal Thomas Toni Myreille Mbamy Catherine Seyler Naomi Wakasugi Thérèse N'dri-Yoman Xavier Anglaret | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 5 | Predictors of double balloon endoscopy outcomes in the evaluation of gastrointestinal bleeding显示文摘AIM:To identify patients' characteristics associated with double balloon endoscopy(DBE)outcomes in investigation of obscure gastrointestinal bleeding(OGIB).METHODS:Retrospective study performed at an academic tertiary referral center.Evaluated endpoints were clinical factors associated with no diagnostic yield or non-therapeutic intervention of DBE performed for OGIB evaluation.RESULTS:We included fifty-five DBE between August 2010 and April 2012.The mean age of the sample was 67 with 32 males(58.2%).Twenty-four DBE had no diagnostic yield and 30 DBE did not require therapy.Non-diagnostic yield was associated with performing two or more DBE studies in one day [odds ratio(OR):13.72,P=0.008],absence of blood transfusions within a year of the DBE(OR:7.16,P=0.03)and absence of ulcers or arteriovenous malformations(AVMs)on prior esophagogastroduodenoscopy(EGD)or colonoscopy(OR:19.30,P=0.033).Non-therapeutic DBE was associated with performing two or more DBE per day(OR:18.579,P=0.007),gastrointestinal bleeding episode within a week of the DBE(OR:11.48,P=0.003),fewer blood transfusion requirements prior to DBE(OR:4.55,P=0.036)and absence of ulcers or AVMs on prior EGD or colonoscopy(OR:8.47,P=0.027).CONCLUSION:Predictors of DBE yield and therapeutic intervention on DBE include blood transfusion requirements,previous endoscopic findings and possibly endoscopist fatigue. | Hisham Hussan Nicholas R Crews Caroline M Geremakis Soubhi Bahna Jennifer L LaBundy Christine Hachem | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，6： | 3 |
| 6 | Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions显示文摘 | Elizabeth M Brunt Christine G Janney Adrian M Di Bisceglie Brent A Neuschwander-Tetri Bruce R Bacon | 1999 | The American Journal of Gastroenterology1999，，9： | 3 |
| 7 | Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions显示文摘 | Elizabeth M Brunt Christine G Janney Adrian M Di Bisceglie Brent A Neuschwander-Tetri Bruce R Bacon | 1999 | The American Journal of Gastroenterology1999，，9： | 2 |
| 8 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 9 | CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges显示文摘 | Philipp Grosse‐Gehling Christine A Fargeas Claudia Dittfeld Yvette Garbe Malcolm R Alison Denis Corbeil Leoni A Kunz‐Schughart | 2012 | J. Pathol2012，，3： | 2 |
| 10 | Translating basic research into clinical practice or what else do we have to learn about olfactory ensheathing cells显示文摘 | Christine R Konstantin W | 2009 | Neurosci Lett2009，456，3： | 1 |
| 11 | The effectiveness of tras-tuzumab (Herceptin) combined with chemotherapy for gastric carcinoma with overexpression of the c-erbB-2 protein显示文摘 | Christine R Raphalle B Laetitia S | 2005 | Gastric Cancer2005，8，： | 1 |
| 12 | Enhancement of mechanical properties of TiN/AlN multilayers by modb lying the number and the quality of interfaces显示文摘 | ANNE T CHRISTOPHE R CHRISTINE C | 2000 | Surface and Coatings Technology2000，124，： | 1 |
| 13 | SiC-matrix composite materials for advanced jet engines显示文摘 | Naslain R Christin F | 2003 | MRS Bull2003，28，9： | 1 |
| 14 | Myocardial cell death in fibrillation and dilated human right artia显示文摘 | CHRISTINE A S FOLLIGUET T CATHERINE R M | 1999 | Circulation1999，34，： | 1 |
| 15 | The new market for federal judicial law clerks显示文摘 | Avery C Christine J Richard P and Alvin E R | 2007 | University of Chicago Law Review2007，，： | 1 |
| 16 | Isolation of a cDNA Encoding a β-1,4 endoglucanase in the root knot nematode Meloidogyne incognita and expression analysis during plant parasitism显示文摘 | MARIE N R BRUNO F CHRISTINE P | 1999 | Mol Plant-Microbe Interact1999，12，7： | 1 |
| 17 | Large Scale Multiple Kernel Learning显示文摘 | Soren S Gunnar R Christin S | 2006 | Journal of Machine Learning Research2006，7，1： | 1 |
| 18 | General mechanisms of prematureovarian failure and clinical check-up显示文摘 | Christin M Braham R | 2008 | Gynecol Obstet Fertil2008，36，9： | 1 |
| 19 | Imaging findings of cochlear nerve de ficiency显示文摘 | CHRISTINE M DAVIDSON H C HARNSBERG ER H R | 2002 | AJNR Am J Neuroradiol2002，4，： | 1 |
| 20 | A meta-analysis of upright position in the second stage to reduce instruments deliveries in women with epidural analgesia显示文摘 | Christine L R | 2005 | Acta Obstet Gynecol Scand2005，84，： | 1 |
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